Eurasian-Origin Gene Segments Contribute to the Transmissibility, Aerosol Release, and Morphology of the 2009 Pandemic H1N1 Influenza Virus (original) (raw)
Figure 2
Pandemic precursor viruses transmit to 50% of exposed ferrets by RD.
Four ferrets were inoculated IN to test the RD transmission of TRS (A) or the Eurasian (B) viruses. Nasal washes were collected on the indicated days. Each bar represents the titer of virus from an individual ferret. Inf stands for infected ferret. The limit of detection is represented as the dashed line and is 100.5 TCID50 per mL. Serum was collected on day 0 and day 14. Anti-influenza antibodies were measured by HAI and neutralization assay (C). The limit of detection is 1∶10 for HAI and 1∶20 for the neutralization assay. Antibody titers in the day 0 sera were below the limit of detection.