Francisella tularensis Harvests Nutrients Derived via ATG5-Independent Autophagy to Support Intracellular Growth (original) (raw)
Figure 2
Autophagic flux and transfer of amino acids in F. tularensis infected cells.
(A) S35 counts in the TCA insoluble fraction of uninfected or infected J774 cells 16 hours post inoculation (mean +/− SEM, 3 independent experiments). (B) S35 counts in the bead purified F. tularensis fraction that was TCA insoluble from either uninfected MEFs or F. tularensis infected MEFs exposed to the indicated treatments (mean +/− SEM, 6 independent experiments) (* p<0.05, **p<0.01, *** <0.001).