Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures (original) (raw)
Fig 5
RSV infection of WT and CX3CR1-/- mice.
For each experiment, WT and CX3CR1-/- mice (3 mice per group) were intranasally inoculated with (A) 106 PFU rgRSV or (B) 105 PFU rgRSV-F, which lacks the G and SH genes and grows to lower titers than rgRSV. Lungs were harvested at 5 dpi and PFU per lung was determined. Data for three rgRSV experiments were combined and expressed as the mean ± s.d. of 9 mice. The two-sided student's t test was used to determine significance.