Effect of Flash Glucose Monitoring Technology on Glycemic Control and Treatment Satisfaction in Patients With Type 2 Diabetes (original) (raw)

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Clinical Care/Education/Nutrition/Psychosocial Research| April 29 2019

Marianna Yaron;

1Diabetes Medical Center, Tel Aviv, Israel

2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Eytan Roitman;

1Diabetes Medical Center, Tel Aviv, Israel

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Genya Aharon-Hananel;

1Diabetes Medical Center, Tel Aviv, Israel

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Zohar Landau;

1Diabetes Medical Center, Tel Aviv, Israel

2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

3Diabetes Unit, E. Wolfson Medical Center, Holon, Israel

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Tali Ganz;

3Diabetes Unit, E. Wolfson Medical Center, Holon, Israel

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Ilan Yanuv;

4Hebrew University, Jerusalem, Israel

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Aliza Rozenberg;

4Hebrew University, Jerusalem, Israel

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Moshe Karp;

1Diabetes Medical Center, Tel Aviv, Israel

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Maya Ish-Shalom;

1Diabetes Medical Center, Tel Aviv, Israel

2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Joelle Singer;

1Diabetes Medical Center, Tel Aviv, Israel

2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Julio Wainstein;

1Diabetes Medical Center, Tel Aviv, Israel

2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

3Diabetes Unit, E. Wolfson Medical Center, Holon, Israel

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Itamar Raz

1Diabetes Medical Center, Tel Aviv, Israel

4Hebrew University, Jerusalem, Israel

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1

M.Y. and E.R. contributed equally to this work.

Diabetes Care 2019;42(7):1178–1184

Citation

Marianna Yaron, Eytan Roitman, Genya Aharon-Hananel, Zohar Landau, Tali Ganz, Ilan Yanuv, Aliza Rozenberg, Moshe Karp, Maya Ish-Shalom, Joelle Singer, Julio Wainstein, Itamar Raz; Effect of Flash Glucose Monitoring Technology on Glycemic Control and Treatment Satisfaction in Patients With Type 2 Diabetes. _Diabetes Care 1 July 2019; 42 (7): 1178–1184. https://doi.org/10.2337/dc18-0166

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OBJECTIVE

To assess treatment satisfaction and the effectiveness of a flash glucose monitoring (FGM) system in patients with type 2 diabetes using insulin.

RESEARCH DESIGN AND METHODS

A total of 101 patients with type 2 diabetes on multiple daily insulin injections (MDI) for at least 1 year were assigned randomly to the FGM intervention (n = 53) or the standard care (control) group (n = 48) and followed for 10 weeks. Both groups were instructed to adjust their insulin doses in face-to-face and telephone visits. Satisfaction with treatment, quality of life, comfort using FGM, HbA1c, and frequency of hypoglycemic events were evaluated.

RESULTS

The intervention group found treatment significantly more flexible (P = 0.019) and would recommend it to their counterparts (P = 0.023). Satisfaction using the FGM system was high. The changes in HbA1c were –0.82% (9 mmol/mol) vs. –0.33% (3.6 mmol/mol) in the intervention and control group, respectively (P = 0.005); in nonprespecified post hoc analysis, 68.6% of the patients in the intervention group had their HbA1c reduced by ≥0.5% (5.5 mmol/mol) compared with 30.2% in the control group (P < 0.001), and 39.2% had their HbA1c reduced by ≥1.0% (10.9 mmol/mol) vs. 18.6% in the control group (P = 0.0023) without an increased frequency of hypoglycemia.

CONCLUSIONS

FGM tends to improve treatment satisfaction and may lead to amelioration of glycemic control in patients with type 2 diabetes on MDI without increasing the frequency of hypoglycemia.

© 2019 by the American Diabetes Association.

2019

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