Thyroid Disorders in Subjects with Down Syndrome: An Update (original) (raw)

Thyroid Disorders in Subjects with Down Syndrome: An Update

Authors

Keywords:

Down syndrome, hypothyroidism, subclinical hypothyroidism, autoimmune thyroid disorders

Abstract

Down syndrome (DS) is the commonest chromosomal disorder among live born infants. DS is associated with increased risk of endocrine abnormalities particularly thyroid gland disorders. The spectrum of thyroid dysfunction in patients with DS include congenital hypothyroidism, subclinical hypothyroidism, acquired hypothyroidism (autoimmune - non autoimmune), and hyperthyroidism. This review will focus on the characteristics of the different presentations of thyroid abnormalities in DS, screening and management recommendations.

Issue

Section

Up to Date: Pediatric Endocrinology Update

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

Amr NH. Thyroid Disorders in Subjects with Down Syndrome: An Update. Acta Biomed. 2018;89(1):132-139. doi:10.23750/abm.v89i1.7120