Posttraining androgens’ enhancement of cognitive performance is temporally distinct from androgens’ increases in affective behavior (original) (raw)

References

• Aggleton, J. P., Hunt, P. R., & Rawlins, J. N. P. (1989). Effects of amygdaloid and amygdaloid-hippocampal lesions on object recognition and spatial working memory in rats. Behavioral Neuroscience, 103, 962–974.
  Article PubMed Google Scholar
• Alexander, G., Packard, M., & Hines, M. (1994). Testosterone has rewarding affective properties in male rats: Implications for the biological basis of sexual motivation. Behavioral Neuroscience, 108, 424–428.
  Article PubMed Google Scholar
• Almeida, O. P. (1999). Sex playing with the mind: Effects of oestrogen and testosterone on mood and cognition. Arquivos de Neuro-psiquiatria, 57, 701–706
  PubMed Google Scholar
• Banfi, S., Cornelli, U., Fonio, W., & Dorigotti, L. (1982). A screening method for substances potentially active on learning and memory. Journal of Pharmacology Methods, 8, 255–263.
  Article Google Scholar
• Beatty, W. W. (1984). Hormonal organization of sex differences in play fighting and spatial behavior. Progress in Brain Research, 61, 315–330.
  Article PubMed Google Scholar
• Belanger, A., Cusan, L., Barden, L., & Dupont, A. (1981). Ovarian progestins, androgens and estrogen throughout the 4-day estrous cycle in the rat. Biology of Reproduction, 24, 591–596.
  Article PubMed Google Scholar
• Berry, B., McMahan, R., & Gallagher, M. (1997). Spatial learning and memory at defined points of the estrous cycle: Effects on performance of a hippocampal-dependent task. Behavioral Neuroscience, 111, 267–274.
  Article PubMed Google Scholar
• Bitran, D., Hilvers, R. J., Frye, C. A., & Erskine, M. S. (1996). Chronic anabolic-androgenic steroid treatment affects brain GABAA receptor-gated chloride ion transport. Life Sciences, 58, 573–583.
  Article PubMed Google Scholar
• Bitran, D., Kellogg, C. K., & Hilvers, R. J. (1993). Treatment with anabolic-androgenic steroid affects anxiety-related behavior and alters the sensitivity of cortical GABAA receptors. Hormones & Behavior, 27, 568–583.
  Article Google Scholar
• Blizard, D. A., Lipman, H. R., & Chen, J. J. (1975). Sex differences in open-field behavior in the rat: The inductive and activational role of gonadal hormones. Physiology & Behavior, 14, 601–608.
  Article Google Scholar
• Boissy, A., & Bouissou, M. F. (1994). Effects of androgen treatment on behavioral and physiological responses of heifers to fear-eliciting situations. Hormones & Behavior, 28, 66–83.
  Article Google Scholar
• Christiansen, K., & Knussmann, R. (1987). Androgen levels and components of aggressive behavior in men. Hormones & Behavior, 21, 170–180.
  Article Google Scholar
• D’Amour, F. E., & Smith, D. L. (1941). A method for determining loss of pain sensation. Journal of Pharmacology & Experimental Therapy, 72, 74–79.
  Google Scholar
• Daniel, J. M., Fader, A. J., Spencer, A. L., & Dohanich, G. P. (1997). Estrogen enhances performance of female rats during acquisition of a radial arm maze. Hormones & Behavior, 32, 217–225.
  Article Google Scholar
• Daniel, J. M., Roberts, S. L., & Dohanich, G. P. (1999). Effects of ovarian hormones and environment on radial maze and water maze performance of female rats. Physiology & Behavior, 66, 11–20.
  Article Google Scholar
• Dawson, J. L. M. (1972). Effects of sex hormones on cognitive style in rats and men. Behavior: General, 2, 21–42.
  Article Google Scholar
• Dunn, R. W., Reed, T. A. W., Copeland, P. D., & Frye, C. A. (1998). The nitric oxide synthase inhibitor 7-nitroindazole displays enhanced anxiolytic eff icacy without tolerance in rats following subchronic administration. Neuropharmacology, 37, 899–904.
  Article PubMed Google Scholar
• Erskine, M. S. (1989). Effect of 5a-dihydrotestosterone and flutamide on the facilitation of lordosis by LHRH and naloxone in estrogenprimed female rats. Physiology & Behavior, 43, 753–759.
  Article Google Scholar
• Erskine, M. S., Hippensteil, M., & Kornberg, E. (1992). Metabolism of dihydrotestosterone to 3α-androstanediol in brain and plasma: Effect on behavioral activity in female rats. Journal of Endocrinology, 134, 183–195.
  Article PubMed Google Scholar
• Fingerhood, M. I., Sullivan, J. T., Testa, M., & Jasinski, D. R. (1997). Abuse liability of testosterone. Journal of Psychopharmacology, 11, 59–63.
  Article PubMed Google Scholar
• Forman, L. J., Tingle, V., Estilow, S., & Cater, J. (1945). The response to analgesia testing is affected by gonadal steroids in the rat. Life Sciences, 45, 447–454.
  Article Google Scholar
• Frye, C. A. (1995). Estrus-associated decrements in water maze task are limited to acquisition. Physiology & Behavior, 57, 5–14.
  Article Google Scholar
• Frye, C. A. (2001). Estradiol prevents inhibitory avoidance deficits and pyknotic cells in the granule layer of the dentate gyrus induced by adrenalectomy in rats. Brain Research, 889, 358–363.
  Article PubMed Google Scholar
• Frye, C. A., Bock, B. C., & Kanarek, R. B. (1992). Hormonal milieu affects tailflick latency in female rats and may be attenuated by access to sucrose. Physiology & Behavior, 52, 699–706.
  Article Google Scholar
• Frye, C. A., & Duncan, J. E. (1994). Progesterone metabolites, effective at the GABAA receptor complex, attenuate pain sensitivity in rats. Brain Research, 643, 194–203.
  Article PubMed Google Scholar
• Frye, C. A., & Duncan, J. E. (1996). Estradiol benzoate potentiates neuroactive steroids’ effects on pain sensitivity. Pharmacology, Biochemistry & Behavior, 53, 27–32.
  Article Google Scholar
• Frye, C. A., Duncan, J. E., Basham, M., & Erskine, M. S. (1996). Behavioral effects of 3α-androstanediol II: Hypothalamic and preoptic area actions via a GABAergic mechanism. Behavioural Brain Research, 79, 119–130.
  Article PubMed Google Scholar
• Frye, C. A., & Lacey, E. H. (1999). The neurosteroids DHEA and DHEAS may influence cognitive performance by altering affective state. Physiology & Behavior, 66, 85–92.
  Article Google Scholar
• Frye, C. A., & Lacey, E. H. (2000). Progestins influence performance on cognitive tasks independent of changes in affective behavior. Psychobiology, 28, 550–563.
  Google Scholar
• Frye, C. A., & McCormick, C. M. (2000). The neurosteroid 3a-Androstanediol prevents inhibitory avoidance deficits and pyknotic cells in the granule layer of the dentate gyrus induced by adrenalectomy in rats. Brain Research, 855, 166–170.
  Article PubMed Google Scholar
• Frye, C. A., McCormick, C. M., Coopersmith, C., & Erskine, M. S. (1996). Effects of paced and non-paced mating stimulation on plasma progesterone, 3α-Diol and corticosterone. Psychoneuroendocrinology, 21, 431–439.
  Article PubMed Google Scholar
• Frye, C. A., Park, D., Tanaka, M., Rosellini, R., & Svare, B. (in press). 3α-androstanediol conditions a place preference. Psychoneuroendocrinology.
• Frye, C. A., Petralia, S. M., & Rhodes, M. E. (2000). Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3α,5α-THP. Pharmacology, Biochemistry & Behavior, 67, 1–10.
  Article Google Scholar
• Frye, C. A., & Reed, T. A. W. (1998). Androgenic neurosteroids: Antiseizure effects in an animal model of epilepsy. Psychoneuroendocrinology, 23, 385–399.
  Article PubMed Google Scholar
• Frye, C. A., Rhodes, M. E., Rosellini, R., & Svare, B. (2001). The testosterone metabolite 3a-androstanediol may mediate the effects of testosterone on conditioned place preference through actions in the nucleus accumbens. Manuscript submitted for publication.
• Frye, C. A., & Sturgis, J. D. (1995). Neurosteroids affect spatial/reference, working and long-term memory of female rats. Behavioral & Neural Biology, 64, 83–96.
  Google Scholar
• Frye, C. A., van Keuran, K. R., & Erskine, M. S. (1996). Behavioral effects of 3a-androstanediol: I. Modulation of sexual receptivity and promotion of GABA-stimulated chloride flux. Behavioural Brain Research, 79, 109–118.
  Article PubMed Google Scholar
• Frye, C. A., van Keuran, K. R., Rao, P. N., & Erskine, M. S. (1996a). Analgesic effects of the neurosteroid 3a-androstanediol. Brain Research, 709, 1–9.
  Article PubMed Google Scholar
• Frye, C. A., van Keuran, K. R., Rao, P. N., & Erskine, M. S. (1996b). Progesterone and 3a-androstanediol conjugated to bovine serum albumin affects estrous behavior when applied to the MBH and POA. Behavioral Neuroscience, 110, 603–612.
  Article PubMed Google Scholar
• Fugger, H. N., Cunningham, S. G., Rissman, E. F., & Foster, T. C. (1998). Sex differences in the activational effects of Era on spatial learning. Hormones & Behavior, 34, 163–170.
  Article Google Scholar
• Galea, L. A. M., Kavaliers, M., Ossenkopp, K.-P., & Hampson, E. (1995). Gonadal hormone levels and spatial learning performance in the Morris water maze in male and female meadow voles, Microtus pennsylvanicus. Hormones & Behavior, 29, 106–125.
  Article Google Scholar
• Gaulin, S. J. C., & Fitzgerald, R. W. (1989). Sexual selection for spatiallearning ability. Animal Behaviour, 37, 322–331.
  Article Google Scholar
• Gee, K. W. (1988). Steroid modulation of the GABA/benzodiazepine receptor-linked chloride ionophore. Molecular Neurobiology, 2, 291–317.
  Article PubMed Google Scholar
• Gouchie, C., & Kimura, D. (1991). The relationship between testosterone levels and cognitive ability patterns. Psychoneuroendocrinology, 16, 323–334.
  Article PubMed Google Scholar
• Hassler, M. (1992). Creative musical behavior and sex hormones: Musical talent and spatial ability in the 2 sexes. Psychoneuroendocrinology, 17, 55–70.
  Article PubMed Google Scholar
• Isgor, C., & Sengelaub, D. R. (1998). Prenatal gonadal steroids affect spatial behavior, CA1 and CA3 pyramidal cell morphology in rats. Hormones & Behavior, 34, 183–198.
  Article Google Scholar
• Janowsky, J. S., Chavez, B., & Orwoll, E. S. (2000). Sex steroids modify working memory. Journal of Cognitive Neuroscience, 12, 407–414.
  Article PubMed Google Scholar
• Janowsky, J. S., Oviatt, S. K., & Orwoll, E. S. (1994). Testosterone influences spatial cognition in older men. Behavioral Neuroscience, 108, 325–332.
  Article PubMed Google Scholar
• Joseph, R., Hess, S., & Birecree, E. (1978). Effect of hormone manipulations and exploration on sex differences in maze learning. Behavioral Biology, 24, 364–377.
  Article PubMed Google Scholar
• Kelsey, J. E., Sanderson, K. L., & Frye, C. A. (2000). Perforant path stimulation produces seizures, loss of hippocampal neurons, and a deficit in spatial mapping in rats which is reduced by prior MK-801. Behavioural Brain Research, 107, 59–69.
  Article PubMed Google Scholar
• Klimek, A. (1985). Use of testosterone in the treatment of cluster headache. European Journal of Neurology, 24, 53–56.
  Article Google Scholar
• Luine, V. N. (1997). Steroid hormone modulation of hippocampal dependent spatial memory. Stress, 2, 21–36.
  Article PubMed Google Scholar
• Luine, V. N., Richards, S. T., Wu, V. Y., & Beck, K. D. (1998). Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters. Hormones & Behavior, 34, 149–162.
  Article Google Scholar
• Luine, V. [N.], & Rodriguez, M. (1994). Effects of estradiol on radial arm maze performance of young and aged rats. Behavioral & Neural Biology, 62, 230–236.
  Article Google Scholar
• Maren, S., De Oca, B., & Fanselow, M. S. (1994). Sex differences in hippocampal and long-term potentiation (LTP) and Pavlovian fear conditioning in rats: Positive correlation between LTP and contextual learning. Brain Research, 661, 25–34.
  Article PubMed Google Scholar
• Markus, E. J., & Zecevic, M. (1997). Sex differences and estrous cycle changes in hippocampus-dependent fear conditioning. Psychobiology, 25, 246–252.
  Google Scholar
• Martini, L. (1982). The 5a-reduction of testosterone in the neuroendocrine structures. Biochemical and physiological implications. Endocrine Reviews, 3, 1–25.
  Article PubMed Google Scholar
• McCarthy, M. M., Felzenberg, E., Robbins, A., Pfaff, D. W., & Schwartz-Giblin, S. (1995). Infusions of diazepam and allopregna allopregnanolone into the midbrain central gray facilitate open-field behavior and sexual receptivity in female rats. Hormones & Behavior, 29, 279–295.
  Article Google Scholar
• McCormick, C. M., McNamara, M., Mukhopadhyay, S., & Kelsey, J. E. (1997). Acute corticosterone replacement reinstates performance on spatial and nonspatial memory tasks 3 months after adrenalectomy despite degeneration in the dentate gyrus. Behavioral Neuroscience, 111, 518–531.
  Article PubMed Google Scholar
• McKeever, W.F., & Deyo, R. A. (1990). Testosterone, dihydrotestosterone, and spatial task performance of males. Bulletin of the Psychonomic Society, 28, 305–308.
  Google Scholar
• McKeever, W. F., Rich, D. A., Deyo, R. A., & Conner, R. L. (1987). Androgens and spatial ability: Failure to find a relationship between testosterone and ability measures. Bulletin of the Psychonomic Society, 25, 438–440.
  Google Scholar
• Meijs-Roelofs, H.M.A., Kramer, P., Gribling-Hegge, L., & Woutersen, P. J.A. (1986). Periovulatory changes in serum concentration and of 5α-androstane-3α, 17β-diol in the androgenized rat. Biology of Reproduction, 35, 890–896.
  Article PubMed Google Scholar
• Meijs-Roelofs, H. M. A., Kramer, P., van Cappellen, W. A., & Woutersen, P. J. A. (1985). Changes in serum concentration and ovarian content of 5-androstane-3α, 17β-diol in the female rat approaching first ovulation. Biology of Reproduction, 32, 301–308.
  Article PubMed Google Scholar
• O’Connell, A., Earley, B., & Leonard, B. E. (1994). Phencyclidine prevents spatial navigation and passive avoidance deficits in ibotenate lesioned rats. Neuropharmacology, 33, 1095–1101.
  Article PubMed Google Scholar
• Packard, M. G. (1998). Posttraining estrogen and memory modulation. Hormones & Behavior, 34, 126–139.
  Article Google Scholar
• Packard, M. G., Cornell, A. H., & Alexander, G. M. (1997). Rewarding affective properties of intra-nucleus accumbens injections of testosterone. Behavioral Neuroscience, 111, 219–224.
  Article PubMed Google Scholar
• Packard, M. G., & Teather, L. A. (1997a). Intra-hippocampal estradiol infusion enhances memory in ovariectomized rats. NeuroReport, 8, 3009–3013.
  Article PubMed Google Scholar
• Packard, M. G., & Teather, L. A. (1997b). Post-training estradiol injections enhance memory in ovariectomized rats: Cholinergic blockade and synergism. Neurobiology of Learning & Memory, 68, 172–188.
  Article Google Scholar
• Pellow, S., & File, S. E. (1986). Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat. Pharmacology, Biochemistry & Behavior, 24, 525–529.
  Article Google Scholar
• Postma, A., Meyer, G., Tuiten, A., van Honk, J., Kessels, R. P., & Thijssen, J. (2000). Effects of testosterone administration on selective aspects of object-location memory in healthy young women. Psychoneuroendocrinology, 25, 563–575.
  Article PubMed Google Scholar
• Roselli, C. E. (1991). Sex differences in androgen receptors and aromatase activity in microdissected regions of the rat brain. Endocrinology, 128, 1310–1315.
  Article PubMed Google Scholar
• Sfikakis, A., Spyraki, C., Sitaras, N., & Varonos, D. (1978). Implication of estrous cycle on conditioned avoidance behavior in the rat. Physiology & Behavior, 21, 441–446.
  Article Google Scholar
• Sherwin, B. B. (1988a). A comparative analysis of the role of androgen in human male and female sexual behavior: Behavioral specificity, critical thresholds, and sensitivity. Psychobiology, 16, 416–425.
  Google Scholar
• Sherwin, B. B. (1988b). Estrogen and/or androgen replacement therapy and cognitive functioning in surgically menopausal women. Psychoneuroendocrinology, 13, 345–357.
  Article PubMed Google Scholar
• Sih, R., Morley, J. E., Kaiser, F. E., Perry, H. M., Patrick, P., & Ross, C. (1997). Testosterone replacement in older hypogonadal men: A 12-month randomized controlled trial. Journal of Clinical Endocrinology & Metabolism, 82, 1661–1667.
  Article Google Scholar
• Silverman, I., Kastuk, D., Choi, J., & Phillips, K. (1999). Testosterone levels and spatial ability in men. Psychoneuroendocrinology, 24, 813–822.
  Article PubMed Google Scholar
• Smith, E. E., Jonides, J., & Koeppe, R. A. (1996). Dissociating verbal and spatial working memory using PET. Cerebral Cortex, 6, 11–20.
  Article PubMed Google Scholar
• Squire, L. R. (1992). Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psychological Review, 99, 195–231.
  Article PubMed Google Scholar
• Stackman, R. W., Blasberg, M. E., Langan, C. J., & Clark, A. S. (1997). Stability of spatial working memory across the estrous cycle of Long-Evans rats. Neurobiology of Learning & Memory, 67, 167–171.
  Article Google Scholar
• Stewart, J., Skvarenina, A., & Pottier, J. (1975). Effects of neonatal androgens on open-field behavior and maze learning in the prepubescent and adult rats. Physiology & Behavior, 14, 291–295.
  Article Google Scholar
• Vandenheede, M., & Bouissou, M. F. (1993). Effect of androgen treatment on fear reactions in ewes. Hormones & Behavior, 27, 435–448.
  Article Google Scholar
• van Goozen, S. H., Cohen-Kettenis, P. T., Gooren, L. J., Frijda, N. H., & van de Poll, N. E. (1994). Activating effects of androgens on cognitive performance: Causal evidence in a group of female-tomale transsexuals. Neuropsychologia, 32, 1153–1157.
  Article PubMed Google Scholar
• Vazquez-Pereyra, F., Rivas-Arancibia, S., Loaeza-Del Castillo, A., & Schneider-Rivas, S. (1995). Modulation of short-term memory by steroid sex hormones. Life Sciences, 56, 255–260.
  Google Scholar
• Venault, P., Chapouthier, G., de Carvalho, L. P., Simiand, J., Morre, M., Dodd, R. H., & Rossier, J. (1986). Benzodiazepine impairs and beta-carboline enhances performance in learning and memory tasks. Nature, 321, 864–866.
  Article PubMed Google Scholar
• Warren, S. G., & Juraska, J. M. (1997). Spatial and nonspatial learning across the rat estrous cycle. Behavioral Neuroscience, 111, 259–266.
  Article PubMed Google Scholar
• Williams, C. L., Barnett, A., & Meck, W. H. (1991). Organizational effects of early gonadal secretions on sexual differentiation in spatial memory. Behavioral Neuroscience, 104, 84–97.
  Article Google Scholar
• Williams, C. L., & Meck, W. H. (1991). The organizational effects of gonadal steroids on sexually dimorphic spatial ability. Psychoneuroendocrinology, 16, 155–176.
  Article PubMed Google Scholar

Download references