Atif Mahmood | Dow University of Health Sciences (original) (raw)

Papers by Atif Mahmood

Research paper thumbnail of Challenges Linked With Adherence to Treatment by Adult TB Patients in Pakistan

IOSR Journal of Dental and Medical Sciences, 2013

To be aware of non compliant TB patients for drug loyalty and also investigating the dread for dr... more To be aware of non compliant TB patients for drug loyalty and also investigating the dread for drugs in them. For public health community, tuberculosis (TB) has accessible confront in the developing countries although curative drugs exist, yet TB has remained the foremost killers among infectious diseases. The TB treatment regimen is long, intensive and fraught with potential side effects. For these reasons, only about 20% of people with TB successfully complete treatment. Cross sectional survey was conducted on a non-probability purposive sample of 349 TB patients attending JPMC Chest OPD, Malir Chest Clinic and Ojha Institute of Chest Diseases, Karachi in the month of June and July, 2007. All the patients who were administered Antituberculous drugs (ATT) under Direct Observed Treatment Strategy (DOTS) in the above mentioned period were included in the study. The total response rate was 93%. Out of 349 TB patients observed, 43% [150] were males and 57% [199] were females. 94% of the patients were following DOTS i.e. they regularly came to the clinics, but 5% were those who did not follow it regularly and skipped the daily medicine. Only 13% have quit taking medication themselves. 60% of the patients experienced side effects of the anti-TB drugs whereas 40% didn't experience any side effects. Proper counseling regarding the treatment options and side effects of the treatment can help reduce the challenges associated with adherence to the TB treatment.

Research paper thumbnail of Perceptions and Preference of Contemporary Teaching Methods among University Students of Pakistan- A Cross-Sectional Survey

IOSR Journal of Nursing and health Science, 2012

To determine difference in the perceptions and preferences of medical and non-medical students ab... more To determine difference in the perceptions and preferences of medical and non-medical students about utilization of different teaching methods. White Board, Overhead Projector, PowerPoint presentations, Computer Assisted (CD ROM's)/Web Based learning and Problem Based learning in order to recommend ways for their optimal utilization. Methods: Cross sectional survey was conducted on a convenient sample of 1173 undergraduate students belonging to medical and non-medical colleges from May 2011 to September 2011. The total response rate was 90.23%. Results: Over all 30.2% of the students chose PBL to be a reliable mode of teaching and 32.4 % believed that it provides a better learning experience. Majority of the students (34.8%, 43.5% and 40.8%) preferred case studies over PBL, Lectures, role playing and video tapes and believed that case studies develops the ability to understand the topic better and it is an interesting and interactive teaching method respectively. Majority of the medical students chose PBL whereas the non-medical students preferred case studies to be the best teaching method. Conclusion: Students have chosen PBL and case studies as the best teaching method and have preferred the integration of different teaching methods for better understanding.

Research paper thumbnail of Statin as a Risk Factor for Cataract in Cases of Antioxidant Gene Polymorphism in Pakistani Population

Journal of Pharmaceutical Research International, 2022

Introduction: Cataract is main cause of reversible blindness and visual impairment. Risk factors ... more Introduction: Cataract is main cause of reversible blindness and visual impairment. Risk factors include anti-hyperlipidemic drugs such as statin. However, the mechanism of statins as a risk factor for cataracts is not clear. The antioxidant effect of statin is reported in some studies while other studies showed negative results. This study was conducted to understand the association of cataract in statin users with antioxidant gene abnormalities. Objective: To investigate the risk factor of statin in the formation of cataracts in the Pakistani population. Methods: This was a multi-centric case-control study in Karachi, Pakistan between September 2019 and 2020. A single nucleotide polymorphism (SNP) at rs2070424 locus for superoxide dismutase (SOD1) gene, at rs1050450 for glutathione peroxidase (GPX) and rs7943316 locus for catalase (CAT), were examined with polymerase chain reaction (PCR) using high resolution melting curve (HRM) technique in 250 cataract patients. Results: The ri...

Research paper thumbnail of Prevalence Of Osteoporosis And Osteopenia Among Pakistani Pre And Post Menopausal Women

IOSR Journal of Dental and Medical Sciences, 2012

A cross-sectional study was conducted on 1416 women (age: 25 years or more), belonging to Pre and... more A cross-sectional study was conducted on 1416 women (age: 25 years or more), belonging to Pre and post-menopausal women (1351 & 65 respectively). All subjects were interviewed by using a structured Performa for prevalence of risk factors. Bone mineral density (BMD) was measured to determine the degree of Osteoporosis and Osteopenia by speed of sound (SOS) and broad band ultrasound attenuation (BUA) in the calcaneus bone. It was observed that 272 (19.2%) amongst all subjects were osteoporotic, 890 (62.9%) osteopenic whereas only 254 (17.9%) were normal. When assessment was done in groups, it was found that out of the total postmenopausal women (n=65), 32 (49.5%) were osteoporotic while 28 (43.1%) were found to be osteopenic. On the other hand, in premenopausal women group (n=1351), 240 (17.83%) were found to be Osteoporotic while 862 (63.8%) were found to be Osteopenic. There was however no significant relation in the BMI of all the three groups. The prevalence of osteoporosis was found to be high in postmenopausal but Osteopenia in premenopausal women was reported to be alarmingly high in premenopausal women probably due to lifestyle and dietary risk factors. There is a need to explore the precise causative factors associated with the high prevalence of Osteopenia recorded in the present study.

Research paper thumbnail of Comparison of level of Stress among Bedside Nurses Working in Different Specialties at Private Sector Tertiary Care Hospital in Karachi, Pakistan

Journal of Research Development in Nursing and Midwifery, 2020

Background: Stressful situation are among the challenging experiences especially in clinical sett... more Background: Stressful situation are among the challenging experiences especially in clinical setting. The aim of this study was to compare the level of work-related stress among nurses working in Intensive Care Units (ICUs), General ward and Emergency setting. Methods: This cross-sectional study was conducted at different private tertiary hospitals of Karachi in 2017-2018. Two stage sampling technique including quota and convenient sampling technique was used to collect the data. A total of 225 participants were recruited. Pre-validated questionnaire was used which contained different stress related categories. Midwives, nursing assistants, part time nurses and nurses employed at management positions were excluded from the study. Data were presented as frequency and percentage and mean and standard deviation. The chi-square test was used for examine association of categorical variables. The SPSS used for data analysis. Results: The mean age of participants was 26.5±2.4 years. Stre...

Research paper thumbnail of Public's Attitude Towards Seeking Healthcare and Their Satisfaction with Health Services

Keywords: Health seeking behavior, satisfaction, socioeconomic determinants, and healthcare barri... more Keywords: Health seeking behavior, satisfaction, socioeconomic determinants, and healthcare barriers. Background: Health is an imperative feature of an individual's life, by and large health status is considered as reduce in illness, low burden of disease and morbidity in general population. It is generally accepted that improved health is not simply controlled level of fertility or reduce in the mortality and morbidity but improvement in the overall productivity of an individual Objectives:To determine the determinant of public attitude towards seeking health service, and identify the level of their satisfaction with healthcare services. Methodology: This is a descriptive cross sectional study which was carried out in private and public hospitals of Karachi and Hyderabad. Questionnaire based survey was conducted to measure the health seeking behavior; as no standardize tool was available on this subject a self-designed questionnaire with the help of relevant studies, that was r...

Research paper thumbnail of A Performance Comparison of Segmentation Techniques for the Urdu Text

Computing Algorithms with Applications in Engineering

Research paper thumbnail of Attitude and Practices of General Practitioners of Sub-Urban Area of Karachi in Lifestyle Counseling and Health Promotion

The objective of the study was to determine the attitude and practices of General Practitioners o... more The objective of the study was to determine the attitude and practices of General Practitioners of sub-urban area of Karachi related to lifestyle counseling and health promotion. It was a cross-sectional study conducted using a survey questionnaire filled by General Practitioners working in Primary Healthcare clinics in Lyari-Korangi area of Karachi. Two hundred and ten GPs were eligible for the survey non-probability purposive sampling. The mean, standard deviation and ranges of all measurements were compared with the norms established by Steiner. All statistical evaluation was performed by SPSS 16 .0 version software, the student t-test were performed to compare the sample with Steiner means. Those GPs assigning a high priority level to preventive medicine also practiced lifestyle counseling and disease promotion more often. Most GPs said they were prepared to counsel patients regarding different lifestyle behaviors. A large percentage of GPs opined that their effectiveness to hel...

Research paper thumbnail of Association of BMI with Testosterone in Infertile Males among Local Population ORIGINAL ARTICLE

Objective: To ascertain association of raised BMI with Testosterone levels among infertile males.... more Objective: To ascertain association of raised BMI with Testosterone levels among infertile males. Methods: A cross sectional study was conducted from April 2010 to March 2011. Sample size was 300 males (147 infertile and 153 healthy fertile control subjects) aged 30 and 60 years, selected from the Jinnah Postgraduate Medical Center (JPMC), Aziz Medical Center and Abbasi Shaheed Hospital, Karachi. All the subjects were grouped to BMI criteria (Ascian pacific region for WHO). They were selected by purposive sampling after a detailed medical history and physical examination. Semen analysis was done and blood samples were collected for serum Testosterone levels. Data was analyzed via SPSS 16.0 by using Analysis of Variances (ANOVA) and independent t test to compare the means and to observe sensitivity of tests and to evaluate the significant association with in the group. Results: A significant negative correlation existed between Testosterone and BMI .Raised BMI appear to have an assoc...

Research paper thumbnail of M (2012) Prevalence Of Osteoporosis And Osteopenia Among Pakistani Pre And Post Menopausal Women

A cross-sectional study was conducted on 1416 women (age: 25 years or more), belonging to Pre and... more A cross-sectional study was conducted on 1416 women (age: 25 years or more), belonging to Pre and post-menopausal women (1351 & 65 respectively). All subjects were interviewed by using a structured Performa for prevalence of risk factors. Bone mineral density (BMD) was measured to determine the degree of Osteoporosis and Osteopenia by speed of sound (SOS) and broad band ultrasound attenuation (BUA) in the calcaneus bone. It was observed that 272 (19.2%) amongst all subjects were osteoporotic, 890 (62.9%) osteopenic whereas only 254 (17.9%) were normal. When assessment was done in groups, it was found that out of the total postmenopausal women (n=65), 32 (49.5%) were osteoporotic while 28 (43.1%) were found to be osteopenic. On the other hand, in premenopausal women group (n=1351), 240 (17.83%) were found to be Osteoporotic while 862 (63.8%) were found to be Osteopenic. There was however no significant relation in the BMI of all the three groups. The prevalence of osteoporosis was found to be high in postmenopausal but Osteopenia in premenopausal women was reported to be alarmingly high in premenopausal women probably due to lifestyle and dietary risk factors. There is a need to explore the precise causative factors associated with the high prevalence of Osteopenia recorded in the present study.

Research paper thumbnail of Prevalence of Risk Factors of Non communicable Diseases Amongst Female

Objective: To determine the prevalence and the differences in the prevalence of risk factors for ... more Objective: To determine the prevalence and the differences in the prevalence of risk factors for noncommunicable diseases among the female prisoners of all four provinces of Pakistan. Method: Cross-sectional study which was conducted at the Female Prison of Karachi (Sindh), Koth Lakh Patt (Punjab), Quetta (Baluchistan) and Haripur Jail (Khyber Pakhtoon Khuwah). Sample size was determined by the rule of thumb and 269 adult female prisoners of all the four Prisons (66% population of each prison) were recruited, thereby, determining one prison of each province of Pakistan, the age of whom ranged from 16 years and onwards. The blood pressure, random blood sugar and anthropometric measurements including height, weight, BMI and waist hip circumference of the prisoners were performed. Result: Among the female prisoners of Pakistan, 71% belonged to Pakistani origin, while 23% (n=61) were foreigners. Amongst the foreigners, 79% belonged to African countries e.g. Nigeria, Guinea etc. Among the female prisoners, 24.9% were smokers of whom 5% smoked a maximum of 40 cigarettes per day. Majority of these prisoners (75.4%) had no access to fruits. Vegetable oil consumption was found in 39% prisoners while 44.2% used ghee, 16.3% were not sure about the type of oil used in their meals. A significance difference was observed in the type of oil consumed in meals in all the four prisons visited (p < 0.01). Among the subjects, 55% were satisfied with the food that they get. The mean BMI assessed was 36.63, 1.57m is the mean height, and 67 kg is the mean weight. 46.5% females were found to have a normal BMI, 26.4% were overweight , while 27.13% were found to be obese. Conclusion: The prevalence of risk factor of Non-communicable diseases in the female prisoners of Pakistan was found to be high. There was a higher incidence of smoking amongst the female prisoners than the normal female population of Pakistan. The dietary habits and less use of Fruits were seen in all the four prisons, thereby, increasing the risk of having Non-communicable diseases

Research paper thumbnail of Y Chromosome Microdeletions in Pakistani Infertile Men

Objective: To determine the prevalence of Y chromosome microdeletions in Pakistani idiopathic inf... more Objective: To determine the prevalence of Y chromosome microdeletions in Pakistani idiopathic infertile men, using multiplex polymerase chain reaction. Patients and Methods: A case control study was conducted on the infertile male patients attending OPD’s of Aziz Medical Hospital and National Center for Fertility Control, Jinnah Post Graduate Medical Center (JPMC), Karachi. A total of 220 primary infertile men, of which 150 (68.2%) had azoospermia, 40 (18.2%) had severe oligozoospermia and 30 (13.6%) had oligozoospermia and 220 fertile men as control group were studied. Six sequence-tagged sites: sY84 and sY86 for AZFa, sY127 and sY134 for AZFb, and sY254 and sY255 for AZFc were used for amplification of the azoospermia factor region of Y chromosome according to the recommendations of European Academy of Andrology and the European Quality Monitoring Network Group. Results: Yq microdeletions were found in (12) 5.45% cases, while none in the control group (p =<0.007). All the micro...

Research paper thumbnail of Perception and Preferences of Undergraduate Medical Students Regarding the Use of Contemporary Teaching Aids at Dow International Medical College, Karachi

Journal of the Dow University of Health Sciences, 2011

In this study, perception and preferences of the medical students’ studying at Dow International ... more In this study, perception and preferences of the medical students’ studying at Dow International Medical Collegehave been described about the use of different teaching aids. Methods: Cross sectional survey was conducted on a stratified random sample of 200 undergraduate medicalstudentsduring the month of October 2010at Dow International Medical College, Karachi, Pakistan. Results: 80% of the students responded to the questions asked. Over all 40% of the students chose PowerPointpresentations as a reliable mode of teaching and favoured it as interesting and interactive teaching aid overProblem Based Learning (28.8%), Audio visual Aid (18.6%) and White Board (12%). They believe thatPowerPoint provides a better learning experience as compared to other teaching tools. Projectors as a teachingtool was rejected by the students. Conclusion: This article serves as a source of valuable information for the faculty members. Students havechosen PowerPoint presentations as the best teaching aid ...

Research paper thumbnail of Hospital Acquired Infections

A hospital is a health care setting that provides care and treatment to patients through trained ... more A hospital is a health care setting that provides care and treatment to patients through trained staff and specialized equipment. Recovery from diseases and attainment of health is crucial for everybody. Therefore, health care professionals gain core position in the treatment of diseases and prevention of other health hazards like Hospital Acquired Infections (HAI). The HAI is one of those hazardous conditions which adversely affect patients thus further contributing to ill health. This term paper defines this scorching issue in depth. It reviews the prevalence of nosocomial infections in relation to the globe and specifically in Pakistan. Furthermore, the paper also explains some of the causes which lead to hospital acquired infections. In addition, the paper also discusses its therapeutic management based on different pharmacological and non-pharmacological interventions. The pharmacological approaches include antibiotics and non-pharmacological include awareness about universal p...

Research paper thumbnail of Effect of Dyslipedemia on Insulin Resistance , in Centrally Obese Adult Groups in Karachi Population

Aim: To observe the effect of dyslipedemia on insulin resistance in centrally obese adult groups.... more Aim: To observe the effect of dyslipedemia on insulin resistance in centrally obese adult groups. Methods: This study was carried out by arranging free camp for obesity in Clifton area and Punjab colony for adults (20-40 years) from November 2010 to April 2011. For assessment hundred overweight patients were involved. After taking history & physical examination, samples were collected for fasting blood sugar, insulin and lipid profile. The BMI, and waist hip ratio was measured by following the criteria of the national heart lung and blood institute. Results: One hundred patients select for the purposes of study. In centrally obese, body mass index was high in female (34.1±0.67) as compared with males (31.68±0.53), but waist hip ratio was elevated in male cases (2.16 ±0.14) as compared to females (1.64±0.17). Statistical analysis was carried out. The lipid profile including, cholesterol (280.4±3.44) and LDL (175.15±3.085) was high in male cases as compared with female cases, choleste...

Research paper thumbnail of A Comparison of Platelet Indices of Normotensive , Hypertensive , and Preeclamptic Pregnant Women in Pakistan

This study aimed to assess and compare the platelet profiles of normotensive, hypertensive, and p... more This study aimed to assess and compare the platelet profiles of normotensive, hypertensive, and preeclamptic pregnant women. Further, to find out if mean platelet volume (MPV) and/or platelet distribution width (PDW) could serve as an indicator of the severity of hypertension and the diagnostic marker of preeclampsia. This is a case-control study, in which we included 300 hypertensive and preeclamptic pregnant females aged between 20 to 40 years. Blood samples were analyzed using the Roche model at Dow Diagnostic Research and Reference laboratory (DDRRL). Data were analyzed using Statistical Package for Social Sciences 23 (SPSS Inc., Chicago, IL). A p-value of less than 0.05 was considered statistically significant. High MPV were observed as 9.57 + 2.6, 10.9 + 5.4 and 12.3 + 34 among control, hypertensive and preeclamptic females. Statistically significant differences were observed between control vs. hypertensive with a p-value of 0.005, and 0.0001 between control vs. preeclampsia....

Research paper thumbnail of Public’s Attitude Towards Seeking Healthcare and Their Satisfaction with Health Services

Background: Health is an imperative feature of an individual’s life, by and large health status i... more Background: Health is an imperative feature of an individual’s life, by and large health status is considered as reduce in illness, low burden of disease and morbidity in general population. It is generally accepted that improved health is not simply controlled level of fertility or reduce in the mortality and morbidity but improvement in the overall productivity of an individual Objectives: To determine the determinant of public attitude towards seeking health service, and identify the level of their satisfaction with healthcare services. Methodology: This is a descriptive cross sectional study which was carried out in private and public hospitals of Karachi and Hyderabad. Questionnaire based survey was conducted to measure the health seeking behavior; as no standardize tool was available on this subject a self-designed questionnaire with the help of relevant studies, that was reviewed by subject experts and the corrections were made based on the experts suggestion. Data was collec...

Research paper thumbnail of “Eating Disorders among MBA Students in a Business School of Karachi

Journal of Nutrition & Food Sciences, 2014

Eating Disorders are crucial and multifaceted distressing and substantial habits distinguished by... more Eating Disorders are crucial and multifaceted distressing and substantial habits distinguished by critical disruptions in eating attitudes. If not treated, eating disorders result in physical problems, psychiatric illnesses and possible mortality. Anorexia nervosa and bulimia nervosa are the two renowned eating disorders around the world. Eating disorders are prevalent in both the genders and all the age groups with females and younger age group more prone towards the development of the disease. Prognosis and treatment of these disorders is critical. A descriptive cross sectional study was designed to evaluate the MBA students in a business school for eating disorders using EAT-26 and SCOFF questionnaires. Data was collected from 150 MBA students during university timings using the non-probability convenient sampling. Written informed consent was obtained from each and every participant and confidentiality and anonymity of data was ensured. SPSS-17 was used for statistical analysis. It was found that out of 150 students, 35 (23.33%) and 16 (10.67%) were at high risk to suffer from eating disorders on EAT-26 and SCOFF scales respectively. Moreover females (41.77%) and younger (31.58%) age group were found to be more vulnerable to eating disorders. It has been concluded that a considerable number of students are susceptible to development of eating disorders, females being more vulnerable than males. It has also been suggested that strategies should be planned to avert incidence of such ailments among students.

Research paper thumbnail of Comparison of level of Stress among Bedside Nurses Working in Different Specialties at Private Sector Tertiary Care Hospital in Karachi, Pakistan

Background: Stressful situation are among the challenging experiences especially in clinical sett... more Background: Stressful situation are among the challenging experiences especially in clinical setting. The aim of this study was to compare the level of work-related stress among nurses working in Intensive Care Units (ICUs), General ward and Emergency setting. Methods: This cross-sectional study was conducted at different private tertiary hospitals of Karachi in 2017-2018. Two stage sampling technique including quota and convenient sampling technique was used to collect the data. A total of 225 participants were recruited. Pre-validated questionnaire was used which contained different stress related categories. Midwives, nursing assistants, part time nurses and nurses employed at management positions were excluded from the study. Data were presented as frequency and percentage and mean and standard deviation. The chi-square test was used for examine association of categorical variables. The SPSS used for data analysis. Results: The mean age of participants was 26.5±2.4 years. Stress...

Research paper thumbnail of Perceptions and Preference of Contemporary Teaching Methods among University Students of Pakistan- A Cross-Sectional Survey

IOSR -JNHS, Oct 1, 2013

To determine difference in the perceptions and preferences of medical and non-medical students ab... more To determine difference in the perceptions and preferences of medical and non-medical students about utilization of different teaching methods. White Board, Overhead Projector, PowerPoint presentations, Computer Assisted (CD ROM's)/Web Based learning and Problem Based learning in order to recommend ways for their optimal utilization. Methods: Cross sectional survey was conducted on a convenient sample of 1173 undergraduate students belonging to medical and non-medical colleges from May 2011 to September 2011. The total response rate was 90.23%. Results: Over all 30.2% of the students chose PBL to be a reliable mode of teaching and 32.4 % believed that it provides a better learning experience. Majority of the students (34.8%, 43.5% and 40.8%) preferred case studies over PBL, Lectures, role playing and video tapes and believed that case studies develops the ability to understand the topic better and it is an interesting and interactive teaching method respectively. Majority of the medical students chose PBL whereas the non-medical students preferred case studies to be the best teaching method. Conclusion: Students have chosen PBL and case studies as the best teaching method and have preferred the integration of different teaching methods for better understanding.

Research paper thumbnail of Challenges Linked With Adherence to Treatment by Adult TB Patients in Pakistan

IOSR Journal of Dental and Medical Sciences, 2013

To be aware of non compliant TB patients for drug loyalty and also investigating the dread for dr... more To be aware of non compliant TB patients for drug loyalty and also investigating the dread for drugs in them. For public health community, tuberculosis (TB) has accessible confront in the developing countries although curative drugs exist, yet TB has remained the foremost killers among infectious diseases. The TB treatment regimen is long, intensive and fraught with potential side effects. For these reasons, only about 20% of people with TB successfully complete treatment. Cross sectional survey was conducted on a non-probability purposive sample of 349 TB patients attending JPMC Chest OPD, Malir Chest Clinic and Ojha Institute of Chest Diseases, Karachi in the month of June and July, 2007. All the patients who were administered Antituberculous drugs (ATT) under Direct Observed Treatment Strategy (DOTS) in the above mentioned period were included in the study. The total response rate was 93%. Out of 349 TB patients observed, 43% [150] were males and 57% [199] were females. 94% of the patients were following DOTS i.e. they regularly came to the clinics, but 5% were those who did not follow it regularly and skipped the daily medicine. Only 13% have quit taking medication themselves. 60% of the patients experienced side effects of the anti-TB drugs whereas 40% didn't experience any side effects. Proper counseling regarding the treatment options and side effects of the treatment can help reduce the challenges associated with adherence to the TB treatment.

Research paper thumbnail of Perceptions and Preference of Contemporary Teaching Methods among University Students of Pakistan- A Cross-Sectional Survey

IOSR Journal of Nursing and health Science, 2012

To determine difference in the perceptions and preferences of medical and non-medical students ab... more To determine difference in the perceptions and preferences of medical and non-medical students about utilization of different teaching methods. White Board, Overhead Projector, PowerPoint presentations, Computer Assisted (CD ROM's)/Web Based learning and Problem Based learning in order to recommend ways for their optimal utilization. Methods: Cross sectional survey was conducted on a convenient sample of 1173 undergraduate students belonging to medical and non-medical colleges from May 2011 to September 2011. The total response rate was 90.23%. Results: Over all 30.2% of the students chose PBL to be a reliable mode of teaching and 32.4 % believed that it provides a better learning experience. Majority of the students (34.8%, 43.5% and 40.8%) preferred case studies over PBL, Lectures, role playing and video tapes and believed that case studies develops the ability to understand the topic better and it is an interesting and interactive teaching method respectively. Majority of the medical students chose PBL whereas the non-medical students preferred case studies to be the best teaching method. Conclusion: Students have chosen PBL and case studies as the best teaching method and have preferred the integration of different teaching methods for better understanding.

Research paper thumbnail of Statin as a Risk Factor for Cataract in Cases of Antioxidant Gene Polymorphism in Pakistani Population

Journal of Pharmaceutical Research International, 2022

Introduction: Cataract is main cause of reversible blindness and visual impairment. Risk factors ... more Introduction: Cataract is main cause of reversible blindness and visual impairment. Risk factors include anti-hyperlipidemic drugs such as statin. However, the mechanism of statins as a risk factor for cataracts is not clear. The antioxidant effect of statin is reported in some studies while other studies showed negative results. This study was conducted to understand the association of cataract in statin users with antioxidant gene abnormalities. Objective: To investigate the risk factor of statin in the formation of cataracts in the Pakistani population. Methods: This was a multi-centric case-control study in Karachi, Pakistan between September 2019 and 2020. A single nucleotide polymorphism (SNP) at rs2070424 locus for superoxide dismutase (SOD1) gene, at rs1050450 for glutathione peroxidase (GPX) and rs7943316 locus for catalase (CAT), were examined with polymerase chain reaction (PCR) using high resolution melting curve (HRM) technique in 250 cataract patients. Results: The ri...

Research paper thumbnail of Prevalence Of Osteoporosis And Osteopenia Among Pakistani Pre And Post Menopausal Women

IOSR Journal of Dental and Medical Sciences, 2012

A cross-sectional study was conducted on 1416 women (age: 25 years or more), belonging to Pre and... more A cross-sectional study was conducted on 1416 women (age: 25 years or more), belonging to Pre and post-menopausal women (1351 & 65 respectively). All subjects were interviewed by using a structured Performa for prevalence of risk factors. Bone mineral density (BMD) was measured to determine the degree of Osteoporosis and Osteopenia by speed of sound (SOS) and broad band ultrasound attenuation (BUA) in the calcaneus bone. It was observed that 272 (19.2%) amongst all subjects were osteoporotic, 890 (62.9%) osteopenic whereas only 254 (17.9%) were normal. When assessment was done in groups, it was found that out of the total postmenopausal women (n=65), 32 (49.5%) were osteoporotic while 28 (43.1%) were found to be osteopenic. On the other hand, in premenopausal women group (n=1351), 240 (17.83%) were found to be Osteoporotic while 862 (63.8%) were found to be Osteopenic. There was however no significant relation in the BMI of all the three groups. The prevalence of osteoporosis was found to be high in postmenopausal but Osteopenia in premenopausal women was reported to be alarmingly high in premenopausal women probably due to lifestyle and dietary risk factors. There is a need to explore the precise causative factors associated with the high prevalence of Osteopenia recorded in the present study.

Research paper thumbnail of Comparison of level of Stress among Bedside Nurses Working in Different Specialties at Private Sector Tertiary Care Hospital in Karachi, Pakistan

Journal of Research Development in Nursing and Midwifery, 2020

Background: Stressful situation are among the challenging experiences especially in clinical sett... more Background: Stressful situation are among the challenging experiences especially in clinical setting. The aim of this study was to compare the level of work-related stress among nurses working in Intensive Care Units (ICUs), General ward and Emergency setting. Methods: This cross-sectional study was conducted at different private tertiary hospitals of Karachi in 2017-2018. Two stage sampling technique including quota and convenient sampling technique was used to collect the data. A total of 225 participants were recruited. Pre-validated questionnaire was used which contained different stress related categories. Midwives, nursing assistants, part time nurses and nurses employed at management positions were excluded from the study. Data were presented as frequency and percentage and mean and standard deviation. The chi-square test was used for examine association of categorical variables. The SPSS used for data analysis. Results: The mean age of participants was 26.5±2.4 years. Stre...

Research paper thumbnail of Public's Attitude Towards Seeking Healthcare and Their Satisfaction with Health Services

Keywords: Health seeking behavior, satisfaction, socioeconomic determinants, and healthcare barri... more Keywords: Health seeking behavior, satisfaction, socioeconomic determinants, and healthcare barriers. Background: Health is an imperative feature of an individual's life, by and large health status is considered as reduce in illness, low burden of disease and morbidity in general population. It is generally accepted that improved health is not simply controlled level of fertility or reduce in the mortality and morbidity but improvement in the overall productivity of an individual Objectives:To determine the determinant of public attitude towards seeking health service, and identify the level of their satisfaction with healthcare services. Methodology: This is a descriptive cross sectional study which was carried out in private and public hospitals of Karachi and Hyderabad. Questionnaire based survey was conducted to measure the health seeking behavior; as no standardize tool was available on this subject a self-designed questionnaire with the help of relevant studies, that was r...

Research paper thumbnail of A Performance Comparison of Segmentation Techniques for the Urdu Text

Computing Algorithms with Applications in Engineering

Research paper thumbnail of Attitude and Practices of General Practitioners of Sub-Urban Area of Karachi in Lifestyle Counseling and Health Promotion

The objective of the study was to determine the attitude and practices of General Practitioners o... more The objective of the study was to determine the attitude and practices of General Practitioners of sub-urban area of Karachi related to lifestyle counseling and health promotion. It was a cross-sectional study conducted using a survey questionnaire filled by General Practitioners working in Primary Healthcare clinics in Lyari-Korangi area of Karachi. Two hundred and ten GPs were eligible for the survey non-probability purposive sampling. The mean, standard deviation and ranges of all measurements were compared with the norms established by Steiner. All statistical evaluation was performed by SPSS 16 .0 version software, the student t-test were performed to compare the sample with Steiner means. Those GPs assigning a high priority level to preventive medicine also practiced lifestyle counseling and disease promotion more often. Most GPs said they were prepared to counsel patients regarding different lifestyle behaviors. A large percentage of GPs opined that their effectiveness to hel...

Research paper thumbnail of Association of BMI with Testosterone in Infertile Males among Local Population ORIGINAL ARTICLE

Objective: To ascertain association of raised BMI with Testosterone levels among infertile males.... more Objective: To ascertain association of raised BMI with Testosterone levels among infertile males. Methods: A cross sectional study was conducted from April 2010 to March 2011. Sample size was 300 males (147 infertile and 153 healthy fertile control subjects) aged 30 and 60 years, selected from the Jinnah Postgraduate Medical Center (JPMC), Aziz Medical Center and Abbasi Shaheed Hospital, Karachi. All the subjects were grouped to BMI criteria (Ascian pacific region for WHO). They were selected by purposive sampling after a detailed medical history and physical examination. Semen analysis was done and blood samples were collected for serum Testosterone levels. Data was analyzed via SPSS 16.0 by using Analysis of Variances (ANOVA) and independent t test to compare the means and to observe sensitivity of tests and to evaluate the significant association with in the group. Results: A significant negative correlation existed between Testosterone and BMI .Raised BMI appear to have an assoc...

Research paper thumbnail of M (2012) Prevalence Of Osteoporosis And Osteopenia Among Pakistani Pre And Post Menopausal Women

A cross-sectional study was conducted on 1416 women (age: 25 years or more), belonging to Pre and... more A cross-sectional study was conducted on 1416 women (age: 25 years or more), belonging to Pre and post-menopausal women (1351 & 65 respectively). All subjects were interviewed by using a structured Performa for prevalence of risk factors. Bone mineral density (BMD) was measured to determine the degree of Osteoporosis and Osteopenia by speed of sound (SOS) and broad band ultrasound attenuation (BUA) in the calcaneus bone. It was observed that 272 (19.2%) amongst all subjects were osteoporotic, 890 (62.9%) osteopenic whereas only 254 (17.9%) were normal. When assessment was done in groups, it was found that out of the total postmenopausal women (n=65), 32 (49.5%) were osteoporotic while 28 (43.1%) were found to be osteopenic. On the other hand, in premenopausal women group (n=1351), 240 (17.83%) were found to be Osteoporotic while 862 (63.8%) were found to be Osteopenic. There was however no significant relation in the BMI of all the three groups. The prevalence of osteoporosis was found to be high in postmenopausal but Osteopenia in premenopausal women was reported to be alarmingly high in premenopausal women probably due to lifestyle and dietary risk factors. There is a need to explore the precise causative factors associated with the high prevalence of Osteopenia recorded in the present study.

Research paper thumbnail of Prevalence of Risk Factors of Non communicable Diseases Amongst Female

Objective: To determine the prevalence and the differences in the prevalence of risk factors for ... more Objective: To determine the prevalence and the differences in the prevalence of risk factors for noncommunicable diseases among the female prisoners of all four provinces of Pakistan. Method: Cross-sectional study which was conducted at the Female Prison of Karachi (Sindh), Koth Lakh Patt (Punjab), Quetta (Baluchistan) and Haripur Jail (Khyber Pakhtoon Khuwah). Sample size was determined by the rule of thumb and 269 adult female prisoners of all the four Prisons (66% population of each prison) were recruited, thereby, determining one prison of each province of Pakistan, the age of whom ranged from 16 years and onwards. The blood pressure, random blood sugar and anthropometric measurements including height, weight, BMI and waist hip circumference of the prisoners were performed. Result: Among the female prisoners of Pakistan, 71% belonged to Pakistani origin, while 23% (n=61) were foreigners. Amongst the foreigners, 79% belonged to African countries e.g. Nigeria, Guinea etc. Among the female prisoners, 24.9% were smokers of whom 5% smoked a maximum of 40 cigarettes per day. Majority of these prisoners (75.4%) had no access to fruits. Vegetable oil consumption was found in 39% prisoners while 44.2% used ghee, 16.3% were not sure about the type of oil used in their meals. A significance difference was observed in the type of oil consumed in meals in all the four prisons visited (p < 0.01). Among the subjects, 55% were satisfied with the food that they get. The mean BMI assessed was 36.63, 1.57m is the mean height, and 67 kg is the mean weight. 46.5% females were found to have a normal BMI, 26.4% were overweight , while 27.13% were found to be obese. Conclusion: The prevalence of risk factor of Non-communicable diseases in the female prisoners of Pakistan was found to be high. There was a higher incidence of smoking amongst the female prisoners than the normal female population of Pakistan. The dietary habits and less use of Fruits were seen in all the four prisons, thereby, increasing the risk of having Non-communicable diseases

Research paper thumbnail of Y Chromosome Microdeletions in Pakistani Infertile Men

Objective: To determine the prevalence of Y chromosome microdeletions in Pakistani idiopathic inf... more Objective: To determine the prevalence of Y chromosome microdeletions in Pakistani idiopathic infertile men, using multiplex polymerase chain reaction. Patients and Methods: A case control study was conducted on the infertile male patients attending OPD’s of Aziz Medical Hospital and National Center for Fertility Control, Jinnah Post Graduate Medical Center (JPMC), Karachi. A total of 220 primary infertile men, of which 150 (68.2%) had azoospermia, 40 (18.2%) had severe oligozoospermia and 30 (13.6%) had oligozoospermia and 220 fertile men as control group were studied. Six sequence-tagged sites: sY84 and sY86 for AZFa, sY127 and sY134 for AZFb, and sY254 and sY255 for AZFc were used for amplification of the azoospermia factor region of Y chromosome according to the recommendations of European Academy of Andrology and the European Quality Monitoring Network Group. Results: Yq microdeletions were found in (12) 5.45% cases, while none in the control group (p =<0.007). All the micro...

Research paper thumbnail of Perception and Preferences of Undergraduate Medical Students Regarding the Use of Contemporary Teaching Aids at Dow International Medical College, Karachi

Journal of the Dow University of Health Sciences, 2011

In this study, perception and preferences of the medical students’ studying at Dow International ... more In this study, perception and preferences of the medical students’ studying at Dow International Medical Collegehave been described about the use of different teaching aids. Methods: Cross sectional survey was conducted on a stratified random sample of 200 undergraduate medicalstudentsduring the month of October 2010at Dow International Medical College, Karachi, Pakistan. Results: 80% of the students responded to the questions asked. Over all 40% of the students chose PowerPointpresentations as a reliable mode of teaching and favoured it as interesting and interactive teaching aid overProblem Based Learning (28.8%), Audio visual Aid (18.6%) and White Board (12%). They believe thatPowerPoint provides a better learning experience as compared to other teaching tools. Projectors as a teachingtool was rejected by the students. Conclusion: This article serves as a source of valuable information for the faculty members. Students havechosen PowerPoint presentations as the best teaching aid ...

Research paper thumbnail of Hospital Acquired Infections

A hospital is a health care setting that provides care and treatment to patients through trained ... more A hospital is a health care setting that provides care and treatment to patients through trained staff and specialized equipment. Recovery from diseases and attainment of health is crucial for everybody. Therefore, health care professionals gain core position in the treatment of diseases and prevention of other health hazards like Hospital Acquired Infections (HAI). The HAI is one of those hazardous conditions which adversely affect patients thus further contributing to ill health. This term paper defines this scorching issue in depth. It reviews the prevalence of nosocomial infections in relation to the globe and specifically in Pakistan. Furthermore, the paper also explains some of the causes which lead to hospital acquired infections. In addition, the paper also discusses its therapeutic management based on different pharmacological and non-pharmacological interventions. The pharmacological approaches include antibiotics and non-pharmacological include awareness about universal p...

Research paper thumbnail of Effect of Dyslipedemia on Insulin Resistance , in Centrally Obese Adult Groups in Karachi Population

Aim: To observe the effect of dyslipedemia on insulin resistance in centrally obese adult groups.... more Aim: To observe the effect of dyslipedemia on insulin resistance in centrally obese adult groups. Methods: This study was carried out by arranging free camp for obesity in Clifton area and Punjab colony for adults (20-40 years) from November 2010 to April 2011. For assessment hundred overweight patients were involved. After taking history & physical examination, samples were collected for fasting blood sugar, insulin and lipid profile. The BMI, and waist hip ratio was measured by following the criteria of the national heart lung and blood institute. Results: One hundred patients select for the purposes of study. In centrally obese, body mass index was high in female (34.1±0.67) as compared with males (31.68±0.53), but waist hip ratio was elevated in male cases (2.16 ±0.14) as compared to females (1.64±0.17). Statistical analysis was carried out. The lipid profile including, cholesterol (280.4±3.44) and LDL (175.15±3.085) was high in male cases as compared with female cases, choleste...

Research paper thumbnail of A Comparison of Platelet Indices of Normotensive , Hypertensive , and Preeclamptic Pregnant Women in Pakistan

This study aimed to assess and compare the platelet profiles of normotensive, hypertensive, and p... more This study aimed to assess and compare the platelet profiles of normotensive, hypertensive, and preeclamptic pregnant women. Further, to find out if mean platelet volume (MPV) and/or platelet distribution width (PDW) could serve as an indicator of the severity of hypertension and the diagnostic marker of preeclampsia. This is a case-control study, in which we included 300 hypertensive and preeclamptic pregnant females aged between 20 to 40 years. Blood samples were analyzed using the Roche model at Dow Diagnostic Research and Reference laboratory (DDRRL). Data were analyzed using Statistical Package for Social Sciences 23 (SPSS Inc., Chicago, IL). A p-value of less than 0.05 was considered statistically significant. High MPV were observed as 9.57 + 2.6, 10.9 + 5.4 and 12.3 + 34 among control, hypertensive and preeclamptic females. Statistically significant differences were observed between control vs. hypertensive with a p-value of 0.005, and 0.0001 between control vs. preeclampsia....

Research paper thumbnail of Public’s Attitude Towards Seeking Healthcare and Their Satisfaction with Health Services

Background: Health is an imperative feature of an individual’s life, by and large health status i... more Background: Health is an imperative feature of an individual’s life, by and large health status is considered as reduce in illness, low burden of disease and morbidity in general population. It is generally accepted that improved health is not simply controlled level of fertility or reduce in the mortality and morbidity but improvement in the overall productivity of an individual Objectives: To determine the determinant of public attitude towards seeking health service, and identify the level of their satisfaction with healthcare services. Methodology: This is a descriptive cross sectional study which was carried out in private and public hospitals of Karachi and Hyderabad. Questionnaire based survey was conducted to measure the health seeking behavior; as no standardize tool was available on this subject a self-designed questionnaire with the help of relevant studies, that was reviewed by subject experts and the corrections were made based on the experts suggestion. Data was collec...

Research paper thumbnail of “Eating Disorders among MBA Students in a Business School of Karachi

Journal of Nutrition & Food Sciences, 2014

Eating Disorders are crucial and multifaceted distressing and substantial habits distinguished by... more Eating Disorders are crucial and multifaceted distressing and substantial habits distinguished by critical disruptions in eating attitudes. If not treated, eating disorders result in physical problems, psychiatric illnesses and possible mortality. Anorexia nervosa and bulimia nervosa are the two renowned eating disorders around the world. Eating disorders are prevalent in both the genders and all the age groups with females and younger age group more prone towards the development of the disease. Prognosis and treatment of these disorders is critical. A descriptive cross sectional study was designed to evaluate the MBA students in a business school for eating disorders using EAT-26 and SCOFF questionnaires. Data was collected from 150 MBA students during university timings using the non-probability convenient sampling. Written informed consent was obtained from each and every participant and confidentiality and anonymity of data was ensured. SPSS-17 was used for statistical analysis. It was found that out of 150 students, 35 (23.33%) and 16 (10.67%) were at high risk to suffer from eating disorders on EAT-26 and SCOFF scales respectively. Moreover females (41.77%) and younger (31.58%) age group were found to be more vulnerable to eating disorders. It has been concluded that a considerable number of students are susceptible to development of eating disorders, females being more vulnerable than males. It has also been suggested that strategies should be planned to avert incidence of such ailments among students.

Research paper thumbnail of Comparison of level of Stress among Bedside Nurses Working in Different Specialties at Private Sector Tertiary Care Hospital in Karachi, Pakistan

Background: Stressful situation are among the challenging experiences especially in clinical sett... more Background: Stressful situation are among the challenging experiences especially in clinical setting. The aim of this study was to compare the level of work-related stress among nurses working in Intensive Care Units (ICUs), General ward and Emergency setting. Methods: This cross-sectional study was conducted at different private tertiary hospitals of Karachi in 2017-2018. Two stage sampling technique including quota and convenient sampling technique was used to collect the data. A total of 225 participants were recruited. Pre-validated questionnaire was used which contained different stress related categories. Midwives, nursing assistants, part time nurses and nurses employed at management positions were excluded from the study. Data were presented as frequency and percentage and mean and standard deviation. The chi-square test was used for examine association of categorical variables. The SPSS used for data analysis. Results: The mean age of participants was 26.5±2.4 years. Stress...

Research paper thumbnail of Perceptions and Preference of Contemporary Teaching Methods among University Students of Pakistan- A Cross-Sectional Survey

IOSR -JNHS, Oct 1, 2013

To determine difference in the perceptions and preferences of medical and non-medical students ab... more To determine difference in the perceptions and preferences of medical and non-medical students about utilization of different teaching methods. White Board, Overhead Projector, PowerPoint presentations, Computer Assisted (CD ROM's)/Web Based learning and Problem Based learning in order to recommend ways for their optimal utilization. Methods: Cross sectional survey was conducted on a convenient sample of 1173 undergraduate students belonging to medical and non-medical colleges from May 2011 to September 2011. The total response rate was 90.23%. Results: Over all 30.2% of the students chose PBL to be a reliable mode of teaching and 32.4 % believed that it provides a better learning experience. Majority of the students (34.8%, 43.5% and 40.8%) preferred case studies over PBL, Lectures, role playing and video tapes and believed that case studies develops the ability to understand the topic better and it is an interesting and interactive teaching method respectively. Majority of the medical students chose PBL whereas the non-medical students preferred case studies to be the best teaching method. Conclusion: Students have chosen PBL and case studies as the best teaching method and have preferred the integration of different teaching methods for better understanding.