The interaction of intestinal epithelial cells and intraepithelial lymphocytes in host defense (original) (raw)
Goodman T, LefranÇois L: Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes. Nature 1988;333: 855–858. ArticlePubMedCAS Google Scholar
Bonneville M, Janeway CA, Ito K, Haser W, Ishida I, Nakanishi N, Tonegawa S: Intestinal intraepithelial lymphocytes are a distinct set of γδ T cells. Nature 1988; 336:479–481. ArticlePubMedCAS Google Scholar
Klein JR: Advances in intestinal T-cell development and function. Immunol Today 1995;16:322–324. ArticlePubMedCAS Google Scholar
Vaage JT, Dissen E, Ager A, Roberts I, Fossum S, Rolstad B: T cell receptor-bearing cells among rat intestinal intraepithelial lymphocytes are mainly α/Β+ and are thymus dependent. Eur J Immunol 1990;20:1193–1196. ArticlePubMedCAS Google Scholar
Jarry A, Cerf-Bensussan N, Brousse N, Seif F, Guy-Grand D: Subsets of CD3+ (T cell receptor α/Β or γ/ δ) and CD3- lymphocytes isolated from normal human gut epithelium display phenotypical features different from their counterparts in peripheral blood. Eur J Immunol 1990;20:1097–1103. ArticlePubMedCAS Google Scholar
VanKerckhove C, Russel GJ, Deusch K, Reich K, Bhan AK, DerSimonian H, Brenner MB: Oligoclonality of human intestinal intraepithelial T cells. J Exp Med 1992;175:57–63. ArticlePubMed Google Scholar
Fangmann J, Schwinzer R, Wonight K: Unusual phenotype of intestinal intraepithelial lymphocytes in the rat: predominance of T cell receptor α/Β+/CD2- cells and high expression of the RT6 alloantigen. Eur J Immunol 1991; 21:753–760. ArticlePubMedCAS Google Scholar
Takimoto H, Nakamura T, Takeuchi M, Sumi Y, Tanaka T, Nomoto K, Yoshikai Y: Age associated increase in number of CD4+CD8+ intestinal intraepithelial lymphocytes in rats. Eur J Immunol 1992; 22:159–164. ArticlePubMedCAS Google Scholar
Rocha B, Vassalli P, Guy-Grand D: Thymic and extrathymic origins of gut intraepitherial lymphocyte populations in mice. J Exp Med 1994;180:681–686. ArticlePubMedCAS Google Scholar
Takeuchi M, Miyazaki H, Mirokawa K, Yokokura T, Yoshikai Y: Age-related changes of T cell subsets in intestinal intraepithelial lymphocytes of mice. Eur J Immunol 1993;23:1409–1411. ArticlePubMedCAS Google Scholar
Mosley RL, Styre D, Klein JR: CD4+CD8+ murine intestinal intraepithelial lymphocyte. Int Immunol 1990;2:361–365. ArticlePubMedCAS Google Scholar
Kimura Y, Sakai T, Takeuchi M, Matsumoto Y, Watanabe K, Yuuki M, Takada T, Yoshikai Y: An unique CD4+ CD8+ intestinal intraepithelial lymphocyte specific for DnaK_(Escherichia coli_ HSP70) may be selected by intestinal microflora of rats. Immunobiology 1996-1997;196:550–566. PubMed Google Scholar
Paliard X, Malefijt RW, deVries JE, Spits H: Interleukin-4 mediates CD8 induction on human CD4+T-cell clones. Nature 1988; 335:642–644. ArticlePubMedCAS Google Scholar
Ramirez F, McKnight AJ, Silva A, Mason D: Glucocorticoid induce the expression of CD8 α chains on concanavalin A-acti vated rat CD4+ T cells: Induction is inhibited by rat recombinant interleukin 4. J Exp Med 1992;176:1551–1559. ArticlePubMedCAS Google Scholar
Reimann J, Rudolphi A: Co-expression of CD8α in CD4+ T cell receptor αΒ+ T cells migrating into the murine small intestine epithelial layer. Eur J Immunol 1995; 25:1580–1588. ArticlePubMedCAS Google Scholar
Balk SP, Ebert EC, Blumenthal RL, McDermott FV, Wucherpfennig KW, Landau SB, Blumberg RS: Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes. Science 1991;253:1411–1415. ArticlePubMedCAS Google Scholar
Regnault A, Cumano A, Vassalli P, Guy-Grand D, Kourilsky, P: Oligoclonal repertoire of the CD8αα and the CD8αΒ TCR-α/Β murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells. J Exp Med 1994;180:1345–1358. ArticlePubMedCAS Google Scholar
Rocha B, Vassalli P, Guy-Grand D: The VΒ repertoire of mouse gut homodimeric a CD8+ intraepithelial T cell receptor α/Β+ lymphocytes reveals a major extrathymic pathway of T cell differentiation. J Exp Med 1991;173:483–486. ArticlePubMedCAS Google Scholar
Murosaki S, Yoshikai Y, Ishida A, Nakamura T, Matsuzaki G, Takimoto H, Yuuki H, Nomoto K: Failure of T cell receptor VΒ negative selection in murine intestinal intra-epithelial lymphocytes. Int Immunol 1991;3: 1005–1013. ArticlePubMedCAS Google Scholar
Regnault A, Levraud JP, Lim A, Moreau C, Cumano A, Kourilsky P: The expansion and selection of T cell receptor αΒ intestinal intraepithelial T cell clones. Eur J Immunol 1996;26:914–915. ArticlePubMedCAS Google Scholar
Beagley KW, Fujihashi K, Black CA, Lagoo AS, Yamamoto M, McGhee JR, Kiyono H: The mycobacterium tuberculosis 71kDa heat-shock protein induces proliferation and cytokine secretion by murine gut intraepithelial lymphocytes. Eur J Immunol 1993;23: 2049–2052. ArticlePubMedCAS Google Scholar
Blumberg RS, Balk SP: Intraepithelial lymphocytes and their recognition of non-classical MHC molecules. Int Rev Immunol 1994; 11:15–30. ArticlePubMedCAS Google Scholar
Nakamura T, Matsuzaki G, Takimoto H, Nomoto K: Age-associated changes in the proliferative response of rat intestinal intraepithelial leukocytes to bacterial antigens. Gastroenterology 1995; 109: 748–754. ArticlePubMedCAS Google Scholar
Sydora BC, Brossay L, Hagenbaugh A, Kronenberg M, Cheroutre H: TAP-independent selection of CD8+ intestinal intraepithelial lymphocytes. J Immunol 1996;156:4209–4216. PubMedCAS Google Scholar
Guy-Grand D, Cuenod-Jabri B, Malassis-Seris M, Selz F, Vassalli P: Complexity of the mouse gut T cell immune system: identification of two distinct natural killer T cell intraepithelial lineages. Eur J Immunol 1996;26:2248–2256. ArticlePubMedCAS Google Scholar
Sakai T, Kimura Y, Inagaki-Ohara K, Kusugami K, Lynch DH, Yoshikai Y: Fas-mediated cytotoxicity by intestinal intraepithelial lymphocytes during acute graftversus-host disease in mice. Gastroenterology 1997;113:168–174. ArticlePubMedCAS Google Scholar
Inagaki-Ohara K, Nishimura H, Inagaki H, Sakai T, Takano M, Lynch DH, Yoshikai Y: Involvement of fas antigen/fas ligand interaction in apoptosis of epithelial cells by intraepithelial lymphocytes in murine small intestine. Lab Invest 1997;77:421–429. PubMedCAS Google Scholar
Fujihashi K, Taguchi T, Aicher WK, McGhee JR, Bluestone JA, Eldridge J H, Kiyono H: Immunoregulatory functions for murine intraepithelial lymphocytes: γ/δ Tcell receptor-positive (TCR+) T cells abrogate oral tolerance, while α/Β TCR+ T cells provide B cell help. J Exp Med 1992;175: 695–707. ArticlePubMedCAS Google Scholar
Komano H, Fujiura Y, Kawaguchi M, Matsumoto S, Hashimoto Y, Obana S, Mombaerts P, Tonegawa S, Yamamoto H, Itohara S, Nanno M, Ishikawa H: Homeostatic regulation of intestinal epithelia by intraepithelial γδ T cells. Proc Natl Acad Sci USA 1995;92:6147–6151. ArticlePubMedCAS Google Scholar
Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL: Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986;136:2348–2357. PubMedCAS Google Scholar
Bottomly K: A functional dichotomy in CD4+ T lymphocytes. Immuno Today 1988;9:268–274. ArticleCAS Google Scholar
Mosmann TR, Coffman RL: Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145–173. ArticlePubMedCAS Google Scholar
Coffman RL, Varkila K., Scotto P, Chatelain R: Role of cytokines in the differentiation of CD4+ T-cell subsets in vivo. Immunol Rev 1991;123:189–207. ArticlePubMedCAS Google Scholar
Kopf M, LeGros G, Bachmann M, Lamers MC, Bluethmann H, Kohler G: Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 1993; 362:245–248. ArticlePubMedCAS Google Scholar
Chen Y, Inobe J, Marks R, Gonnella P, Kuchroo VK, Weiner HL: Peripheral depletion of antigenreactive T cell in oral tolerance. Nature 1995;376:177–180. ArticlePubMedCAS Google Scholar
Fukaura H, Kent SC, Pietrusewicz MJ, Khoury SJ, Weiner HL, Hafler DA: Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-gb1-secreting Th3 cells by oral administration of myelin in multiple sclerosis patients. J Clin Invest 1996;98:70–77. ArticlePubMedCAS Google Scholar
Fujihashi K, Yamamoto M, McGhee JR, Beagley KW, Kiyono H: Function of αΒ TCR+ intestinal intraepithelial lymphocytes: Th1-and Th2-type cytokine production by CD4+CD8-and CD4+CD8+ T cells for helper activity. Int Immunol 1993;5:1473–1481. ArticlePubMedCAS Google Scholar
He YW, Malek TR: Interkeukin-7 receptor a is essential for the development of γδ+ T cells, but not natural killer cells. J Exp Med 1996;184:289–293. ArticlePubMedCAS Google Scholar
Maki K, Sunaga S, Komagata Y, Kodaira Y, Mabuchi A, Karasuyama H, Yokomuro K, Miyazaki J, Ikuta K: Interleukin 7 receptordeficient mice lack γδ T cells. Proc Natl Acad Sci USA 1996;93: 7172–7177. ArticlePubMedCAS Google Scholar
Puddington L, Olson S, LefranÇois L: Interactions between stem cell factor and c-Kit are required for intestinal immune system homeostasis. Immunity 1994;l:733–739. Article Google Scholar
Inagaki-Ohara K, Nishimura H, Mitani A, Yoshikai Y: Interleukin-15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing γδ T cell receptor in mice. Eur J Immunol 1997;27:2885–2891. ArticlePubMedCAS Google Scholar
Giri JG, Ahdieh M, Eisenman J, Shanebeck K, Grabstein KH, Kumaki S, Namen A, Park LS, Cosman D, Anderson D: Utilization of the Β and γ chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J 1994;13:2822–2830. PubMedCAS Google Scholar
Armitage RJ, Macduff BM, Eisenman J, Paxton R, Grabstein KH: IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. J Immunol 1995;154:483–490. PubMedCAS Google Scholar
Carson WE, Giri JG, Lindemann MJ, Linett ML, Ahdieh M, Paxton R, Anderson D, Eisenmann J, Grabstein K, Caligiuri MA: Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp Med 1994;180: 1395–1403. ArticlePubMedCAS Google Scholar
Nishimura H, Hiromatsu K, Kobayashi N, Grabstein KH, Paxton R, Sugamura K, Bluestone J A, Yoshikai Y: IL-15 is a novel growth factor for murine γδ T cells induced by Salmonella infection. J Immunol 1996;156:663–669. PubMedCAS Google Scholar
Grabstein KH, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, Beers C, Richardson J, Schoenborn MA, Ahdieh M, Johnson L, Alderson MR, Watson JD, Anderson DM, Giri JG: Utilization of the Β and γ chains of a T cell growth factor that interacts with the Β chain of the interleukin-2 receptor. Science 1994;264:965–967. ArticlePubMedCAS Google Scholar
Ellis RE, Yuan J, Horvitz HR: Mechanosms and functions of cells death. Annu Rev Cell Biol 1991; 7:663–698 ArticlePubMedCAS Google Scholar
Iwanaga T, Hoshi O, Han H, Takahashi-Iwanaga H, Uchiyama Y, Fujita T. Lamina propria macrophages involved in cell death(apoptosis) of enterocytes in the small intestine of rats. Arch Histol Cytol. 1994;57:267–276. PubMedCAS Google Scholar
Pottem CS, Loeffler M: Stemcells: attributes, cycles, spirals, pitfalls, and uncertainties: Lessons for and from the crypt. Development 1990; 110:1001–1020. Google Scholar
Guy-Grand D, Cerf-Bensussan N, Malissen B, Malassis-Seris M, Briottet C, Vassalli P: Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J Exp Med 1991;173:47–481. Google Scholar
LefranÇois L: Phenotypic complexity of intraepithelial lymphocytes of the small intestine. J Immunol 1991;147:1746–1750. PubMed Google Scholar
Barrett TA, Gajewski TF, Danielpour D, Chang EB, Beagley KW, Bluestone JA. Differential function of intestinal intraepithelial lymphocyte subsets. J Immunol 1992;149:1124–1130. PubMedCAS Google Scholar
Guy-Grand D, Malassis-Seris M, Briottet C, Vassalli P. Cytotoxic differentiation of mouse gut thymodependent and independent intraepithelial T lymphocytes is induced locally. Correlation between functional assays, presence of perforin and granzyme transcripts, and cytoplasmic granules. J Exp Med 1991;173:1549–1552. ArticlePubMedCAS Google Scholar
Itoh N, Yonehara S, Ishii, Yonehara M, Mizushima SI, Sameshima M, Hase A, Seto Y, Nagata S: The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 1991;66:233–243. ArticlePubMedCAS Google Scholar
Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, LiWeker M, Richards S, Dhein J, Trauth BC, Ponstingl H, Krammer PH: Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily: sequence identity with the Fas antigen. J Biol Chem 1992;267: 10709–10715. PubMedCAS Google Scholar
Watanabe-Fukunaga R, Brannan IC, Itoh N, Yonehara S, Copeland GN, Jenkins AN, Nagata S: The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol 1992;148:1274–1279. PubMedCAS Google Scholar
Suda T, Takahashi T, Golstein P, Nagata S: Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993; 75:1169–1178. ArticlePubMedCAS Google Scholar
Arase H, Arase N, Kobayashi Y, Nishimura Y, Yonehara S, Onoe K: Cytotoxicity of Fresh NK1.1+T cell receptor α/Β+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target. J Exp Med 1994;180:423–432. ArticlePubMedCAS Google Scholar
Suda T, Okazaki T, Naito Y, Yokota T, Arai N, Ozaki S, Nakao K, Nagata S: Expression of the Fas ligand in cells of T cell lineage. J Immunol 1995;154:3806–3813. PubMedCAS Google Scholar
Ramsdell F, Seaman MS, Miller RE, Picha KS, Kennedy MK, Lynch DH: Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activationinduced cell death. Int Immnuol 1994;6:1545–1553. ArticleCAS Google Scholar
Cerf-Bensussan, Quaroni NA, Kurnick JT, Bhan AK: Intraepithelial lymphocytes modulate la expression by intestinal epithelial cells. J Immunol 1984; 132:2244–2249. PubMedCAS Google Scholar
Petit A, Ernst PB, Befus AD, Clark DA, Rosenthal KL, Ishizuka T, Bienenstock J: Murine intestinal intraepithelial lymphocytes: I—Relationship of a novel Thy-1-, Lyt-1-, Lyt-2+, granulated subpopulation to natural killer cells and mast cells. Eur J Immunol 1985;15:211–215. ArticlePubMedCAS Google Scholar
Brunner T, Mogil JR, La Face D, Yoo JN, Mahboubi A, Echeverri F, Martin JS, Force RW, Lynch HD, Ware FC, Green RD: Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995;373: 441–444. ArticlePubMedCAS Google Scholar
Ju TS, Panka JD, Cui H, Ettinger R, El-Khatib M, Sherr HD, Stanger ZB, Marshak-Rothstein A: Fas(CD95)/Fas L interactions required for programmed cell death after T-cell activation. Nature 1995; 373:444–448. ArticlePubMedCAS Google Scholar
Dhein J, Walczak H, BÄumler C, Debatin KM, Krammer PH: Autocrine T-cell suicide mediated by APO-l(Fas/CD95). Nature 1995; 373:438–441. ArticlePubMedCAS Google Scholar
Bamford RN, Grant AJ, Burton JD, Peters C, Kurys G, Goldman CK, Brennan J, Roessler E, Waldmann TA: The interleukin (IL) 2 receptor Β chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Nat Acad Sci USA 1994;91:4940–4944. ArticlePubMedCAS Google Scholar
Washizu J, Nishimura H, Nakamura Y, Yoshikai Y: The NF-kB binding sites is essential for transcriptional activation of the IL-15 gene. Immunogenetics 1998;48:l-7 Article Google Scholar
Nishimura H, Washizu J, Nakamura N, Enomoto A, Yoshikai Y: Translational efficiency is upregulated by alternative exon in murine IL-15 mRNA. J Immunol 1998;160:936–942. PubMedCAS Google Scholar
Reinecker HC, MacDermott RP, Mirau S, Dignass A, Podolsky DK: Intestinal epithelial cells both express and respond to interleukin 15. Gastroenterology 1996;111: 1706–1713. ArticlePubMedCAS Google Scholar
Doherty TM, Seder RA, Sher A: Induction and regulation of IL-15 expression in murine macrophages. J Immunol 1996;156:735–741. PubMedCAS Google Scholar
Jullien D, Sieling PA, Uyemura K, Mar ND, Rea TH, Modlin RL: IL-15, an immunomodulator of T cell responses in intracellular infection. J Immunol 1997;158:800–806. PubMedCAS Google Scholar
Chehimi J, Marshall JD, Salvucci O, Frank I, Chehimi S, Kawecki S, Bachelier D, Rifat S, Chouaib S: IL-15 enhances immune functions during HIV infection. J Immunol 1997;158:5978–5987. PubMedCAS Google Scholar
Khan IA, Kasper LH: IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice. J Immunol 1996;157:2103–2108. PubMedCAS Google Scholar
Kakumu S, Okumura A, Ishikawa T, Yano M, Enomoto A, Nishimura H, Yoshioka K, Yoshikai Y: Serum levels of IL-10, IL-15 and soluble tumour necrosis factoralpha (TNF-alpha) receptors in type C chronic liver disease. Clin Exp Immunol 1997;109:458–463. ArticlePubMedCAS Google Scholar
Yamamoto S, Russ F, Teixeira HC, Conradt P, Kaufmann SH: Listeria monocytogenes-induced gamma interferon secretion by intestinal intraepithelial gamma/delta T lymphocytes. Infect Immun 1993;61: 2154–2161. PubMedCAS Google Scholar
Yamamoto M, Fujihashi K, Beagley KW, McGhee JR, Kiyono H: Cyokine synthesis by intestinal intraepithelial lymphocytes. J Immunol 1993;150:106–114. PubMedCAS Google Scholar
Baeuerle PA, Henkel T: Function and activation of NF-kB in ths immune system. Annu Rev Immunol 1994;12:141–179. PubMedCAS Google Scholar
Naumann M, Wessler S, Bartsch CWieland B, Meyer TF: Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor kappaB and activator protein 1 and the induction of inflammatory cytokines. J Exp Med 1997;186: 247–258. ArticlePubMedCAS Google Scholar
Mengaud J, Ohayon H, Gounon P, Mege RM, Cossart P: E-cadherin is the receptor for internalin, a surface protein required for entry of_Lmonocytogenes_ into epithelial cells. Cell 1996;84:923–932. ArticlePubMedCAS Google Scholar
Boller K, Vestweber D, Kemler R: Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells. J Cell Biol 1985; 100:327–332. ArticlePubMedCAS Google Scholar
Cepek KL, Shaw SK, Parker CM, Russell GJ, Morrow JS, Rimm DL, Brenner MB: Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin. Nature 1994;372:190–193. ArticlePubMedCAS Google Scholar
Hermiston ML, Gordon JI: Invivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J Cell Biol 1995;129:489–506. ArticlePubMedCAS Google Scholar
Kirkpatrick C, Peifer M: Not just glue: cell-cell junctions as cellular signaling centers. Curr Opin Genet Dev 1995;5:56–65. ArticlePubMedCAS Google Scholar
Mason I: Cell signaling. Do adhesion molecules signal via FGF receptors? Curr Biol 1994;4:1158–1161. ArticlePubMedCAS Google Scholar
Carson WE, Ross ME, Baiocchi RA, Marien MJ, Boiani N, Grabstein K, Caligiuri MA: Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro. J Clin Invest 1995;96: 2578–2582. PubMedCAS Google Scholar
Ohteki T, Ho S, Suzuki H, Mak TW, Ohashi PS: Role for IL-15/ IL-15 Receptor Β-chain in natural killer 1.1+T cell receptor-αΒ+ cell development. J Immunol 1997;159:5931–5935. PubMedCAS Google Scholar
Warren HS, Kinnear BF, Kastelein RL, Lanier LL: Analysis of the costimulatory role of IL-2 and IL-15 in initiating proliferation of resting (CD56dim) human NK cells. J Immunol 1996; 156: 3254–3259. PubMedCAS Google Scholar
Voss SD, Sondel PM, Robb RJ: Characterization of the interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: association of the p64 IL-2R gamma chain with the IL-2R beta chain in functional intermediate-affinity IL-2R. J Exp Med 1992;176:531–541. ArticlePubMedCAS Google Scholar
DiSanto JP, Muller W, Guy-Grand D, Fischer A, Rajewsky K: Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain. Proc Natl Acad Sci USA 1995;92:377–381. ArticlePubMedCAS Google Scholar
Suzuki H, Duncan GS, Takimoto H, Mak TW: Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor Β chain. J Exp Med 1997;185:499–505. ArticlePubMedCAS Google Scholar
Tanaka T, Kitamura F, Nagasaka Y, Kuida K, Suwa H, Miyasaka M: Selective long-term elimination of natural killer cells in vivo by an anti-interleukin 2 receptor beta chain monoclonal antibody in mice. J Exp Med 1993;178: 1103–1107. ArticlePubMedCAS Google Scholar
Lodolce JP, Boone DL, Chai S, Swain RE, Dassopoulos T, Trettin S, Ma AIL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998; 9:669–676. ArticlePubMedCAS Google Scholar
Hiromatsu K, Yoshikai Y, Matsuzaki G, Ohga S, Muramori K, Matsumoto K, Bluestone JA, Nomoto K: A protective role of 65-kDa heat shock protein-specific γδ T cells in primary infection with Listeria monocytogenes in mice. J Exp Med 1992;175:49–56. ArticlePubMedCAS Google Scholar
Kaufmann SHE, Emoto M, Szalay G, Barsig J, Flesch IEA: Interleukin-4 and listeriosis. Immunol Rev 1997;158:95–105. ArticlePubMedCAS Google Scholar
North RJ, Dunn PL, Conlan JW: Murine listeriosis as a model of antimicrobial defense. Immunol Rev 1997;158:27–36. ArticlePubMedCAS Google Scholar
Yamada K, Kimura Y, Nishimura H, Namii Y, Murase M, Yoshikai Y: Characterization of CD4+ CD8αα+ and CD4- CD8αα+ intestinal intraepithelial lymphocytes in rats. Int lmunol 1999;11:21–28. ArticleCAS Google Scholar
Hirose K, Suzuki H, Nishimura H, Mitani A, Washizu J, Matsuguchi T, Yoshikai Y: Interleukin-15 might be responsible early activation of intestinal intraepithelial lymphocytes after oral infection with Listeria monocytogenes in rats. Infect Immun 1998;66:5677–5683. PubMedCAS Google Scholar
Mitani A, Nishimura H, Hirose K, Washizu J, Kimura Y, Tanaka S, Noguchi T, Yoshikai Y: Interleukin-15 might be responsible for early activation of intestinal intraepithelial lymphocytes after oral infection with Listeria monocytogenes in mice. Immunolgy in press. 1999.
Hirose K, Nishimura H, Matsuguchi T, Yoshikai Y: Endogenous IL-15 might be responsible for early protection by natural killer cells against infection with avirulent strain of Salmonella choleraesuis in mice. J Leukocyte Biol in press, 1999.
Kimura K, Nishimura H, Kirose K, Matsuguchi T, Nimura Y, Yoshikai Y: Immunogene therapy for murine fibrosarcoma using IL-15 gene with high translation efficiency. Eur J Immunol in press 1999.