Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases (original) (raw)
Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ et al. (2002). Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell1: 269–277. ArticleCAS Google Scholar
Boockvar JA, Kapitonov D, Kapoor G, Schouten J, Counelis GJ, Bogler O et al. (2003). Constitutive EGFR signaling confers a motile phenotype to neural stem cells. Mol Cell Neurosci24: 1116–1130. ArticleCAS Google Scholar
Cheng LC, Pastrana E, Tavazoie M, Doetsch F . (2009). miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat Neurosci12: 399–408. ArticleCAS Google Scholar
Ciafrè SA, Galardi S, Mangiola A, Ferracin M, Liu CG, Sabatino G et al. (2005). Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun334: 1351–1358. Article Google Scholar
Conaco C, Otto S, Han J-J, Mandel G . (2006). Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci USA103: 2422–2427. ArticleCAS Google Scholar
Conti A, Aguennouz MH, La Torre D, Tomasello C, Cardali S, Angileri F et al. (2009). miR-21 and 221 upregulation and miR-181b downregulation in human grade II–IV astrocytic tumors. J Neurooncol93: 325–332. ArticleCAS Google Scholar
Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC . (2001). PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev15: 1913–1925. ArticleCAS Google Scholar
Doetsch F, Petreanu L, Caille I, Garcia-Verdugo J-M, Alvarez-Buylla A . (2002). EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron36: 1021–1034. ArticleCAS Google Scholar
Filipowicz W, Bhattacharyya SN, Sonenberg N . (2008). Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet9: 102–114. ArticleCAS Google Scholar
Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A et al. (2007). Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev21: 2683–2710. ArticleCAS Google Scholar
Gangaraju VK, Lin H . (2009). MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol10: 116–125. ArticleCAS Google Scholar
Godlewski J, Nowicki MO, Bronisz A, Williams S, Otsuki A, Nuovo G et al. (2008). Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res68: 9125–9130. ArticleCAS Google Scholar
Hatley ME, Patrick DM, Garcia MR, Richardson JA, Bassel-Duby R, van Rooij E et al. (2010). Modulation of K-Ras-dependent lung tumorigenesis by microRNA-21. Cancer Cell18: 282–293. ArticleCAS Google Scholar
Huse JT, Brennan C, Hambardzumyan D, Wee B, Pena J, Rouhanifard SH et al. (2009). The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. Genes Dev23: 1327–1337. ArticleCAS Google Scholar
Jackson EL, Garcia-Verdugo JM, Gil-Perotin S, Roy M, Quinones-Hinojosa A, VandenBerg S et al. (2006). PDGFR±-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron51: 187–199. ArticleCAS Google Scholar
Krichevsky AM, King KS, Donahue CP, Khrapko K, Kosik KS . (2003). A microRNA array reveals extensive regulation of microRNAs during brain development. RNA9: 1274–1281. ArticleCAS Google Scholar
Krichevsky AM, Sonntag K-C, Isacson O, Kosik KS . (2006). Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells24: 857–864. ArticleCAS Google Scholar
Lewis BP, Shih Ih, Jones-Rhoades MW, Bartel DP, Burge CB . (2003). Prediction of mammalian microRNA targets. Cell115: 787–798. ArticleCAS Google Scholar
Liu C, Sage JC, Miller MR, Verhaak RG, Hippenmeyer S, Vogel H et al. (2011). Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell146: 209–221. ArticleCAS Google Scholar
Liu T, Papagiannakopoulos T, Puskar K, Qi S, Santiago F, Clay W et al. (2007). Detection of a microRNA signal in an in vivo expression set of mRNAs. PLoS One2: e804. Article Google Scholar
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D et al. (2005). MicroRNA expression profiles classify human cancers. Nature435: 834–838. ArticleCAS Google Scholar
Marumoto T, Tashiro A, Friedmann-Morvinski D, Scadeng M, Soda Y, Gage FH et al. (2009). Development of a novel mouse glioma model using lentiviral vectors. Nat Med15: 110–116. ArticleCAS Google Scholar
Mukasa A, Wykosky J, Ligon KL, Chin L, Cavenee WK, Furnari F . (2010). Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence. Proc Natl Acad Sci107: 2616–2621. ArticleCAS Google Scholar
: Network TCGA (2008). Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature455: 1061–1068. Article Google Scholar
Neveu P, Kye MJ, Qi S, Buchholz DE, Clegg DO, Sahin M et al. (2010). MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell7: 671–681. ArticleCAS Google Scholar
Papagiannakopoulos T, Shapiro A, Kosik KS . (2008). MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res68: 8164–8172. ArticleCAS Google Scholar
Piccirillo SGM, Reynolds BA, Zanetti N, Lamorte G, Binda E, Broggi G et al. (2006). Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature444: 761–765. ArticleCAS Google Scholar
Shih AH, Dai C, Hu X, Rosenblum MK, Koutcher JA, Holland EC . (2004). Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Res64: 4783–4789. ArticleCAS Google Scholar
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T et al. (2004). Identification of human brain tumour initiating cells. Nature432: 396–401. ArticleCAS Google Scholar
Stiles CD, Rowitch DH . (2008). Glioma stem cells: a midterm exam. Neuron58: 832–846. ArticleCAS Google Scholar
Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Greenwald DR et al. (2010). Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs. Science328: 1031–1035. ArticleCAS Google Scholar
Verhaak RGW, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD et al. (2010). Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell17: 98–110. ArticleCAS Google Scholar
Visvanathan J, Lee S, Lee B, Lee JW, Lee S-K . (2007). The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev21: 744–749. ArticleCAS Google Scholar
Wuchty S, Arjona D, Li AG, Kotliarov Y, Walling J, Ahn S et al. (2011). Prediction of associations between microRNAs and gene expression in glioma biology. PLoS One6: e14681. ArticleCAS Google Scholar
Xu N, Papagiannakopoulos T, Pan GJ, Thomson JA, Kosik KS . (2009). MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell137: 647–658. ArticleCAS Google Scholar
Zhang Y, Chao T, Li R, Liu W, Chen Y, Yan X et al. (2009). MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. J Mol Med87: 43–51. ArticleCAS Google Scholar
Zhang Y, Zhang Y-f, Bryant J, Charles A, Boado RJ, Pardridge WM . (2004). Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer. Clin Cancer Res10: 3667–3677. ArticleCAS Google Scholar
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen A-J et al. (2008). p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature455: 1129–1133. ArticleCAS Google Scholar