Castleman disease - Weblio 英和・和英辞典 (original) (raw)
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例文
The treatment agent for rheumatoid arthritis, juvenile chronic arthritis, and Castleman's disease which has, as an active ingredient, the IL-6 receptor antibody having improved material properties, safety, immunogenicity, pharmacokinetics (retentivity in blood plasma), and antigen neutralization which are superior to tocilizumab, provided by properly combining CDR region amino acid sequence modification, variable region amino acid sequence modification, and constant region amino acid sequence modification.例文帳に追加
ＣＤＲ領域アミノ酸配列の改変、可変領域アミノ酸配列の改変、定常領域アミノ酸配列の改変を適切に組み合わせることでＴＯＣＩＬＩＺＵＭＡＢより優れた抗原中和能、薬物動態（血漿中滞留性）、免疫原性、安全性、物性が改善された抗ＩＬ−６受容体抗体を有効成分とする関節リウマチ、小児慢性関節炎またはキャッスルマン病の治療剤。 - 特許庁