Browse by Glasgow Author (original) (raw)

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Number of items: 130.

2025

Bilsland, A. E. et al. (2025)Relative telomere length and senescence-associated inflammatory cytokines as blood-based prognostic markers in patients with advanced or resectable gastro-oesophageal adenocarcinoma. British Journal of Cancer, (doi: 10.1038/s41416-025-03221-z) (PMID:41249451) (Early Online Publication)

Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580, Smykowski, Anja, Welisch, Gaston, Mannarprayil, Nilanjana, Emadi, Azadeh ORCID: https://orcid.org/0000-0001-7079-5011, De Smet, Ise, Chipole, Bong’eni, Yousafzai, Yasar, Thorne, John and van Teijlingen Bakker, Nikki(2025)Career Moments: Stories that Shape our Journeys. Project Report. OSF.(doi: 10.17605/OSF.IO/VQNS2).

Keith, N. et al. (2025)Reciprocal Systems of Health in the Climate Era: Personal, Public & Planetary Health. (doi: 10.17605/OSF.IO/UHR94) [Exhibitions]

Jones, R. et al. (2025)Driving the Carbon Economy through Healthcare. Project Report. OSF.(doi: 10.17605/OSF.IO/DHACN).

van Duuren, Paul, Wieringa, Thomas H., Duiverman, Marieke, Witjes, Max, Snijder, Anke, Welisch, Gaston, Smykowski, Anja and Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580(2025)Reimagining Patient Involvement in Research. Project Report. OSF.(doi: 10.17605/OSF.IO/5H9DY).

2024

Keith, N. et al. (2024)Emerging Ecologies of Health, Heritage, and Habitat: Looking into Living and Working in 2033. (doi: 10.17605/OSF.IO/BTNZ9) [Exhibitions]

Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580, Ross, Kirsty, Campbell, Hannah, McCrum, Patrick, Uribe, Valentina and Rowan, Fraser(2024)Designing Future Experiences: The value of exhibition spaces as creative environments for collaborative, multidisciplinary research, exhibitions, and audiences. Project Report. OSF.(doi: 10.17605/OSF.IO/N7MD9).

Skeldon, K. et al. (2024)HACK the ARC - A Grassroots Improvement Initiative. Project Report. OSF.(doi: 10.17605/OSF.IO/WSTZV).

Welisch, Gaston, Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580, Jones, Rob ORCID: https://orcid.org/0000-0002-2904-6980 and Hanna, Catherine ORCID: https://orcid.org/0000-0002-0907-7747(2024)Creative approaches to reimagining patient and public involvement (PPI) in cancer research. Project Report. OSF.(doi: 10.17605/OSF.IO/243XN).

Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580 and Donaldson, Mary ORCID: https://orcid.org/0000-0002-1936-3499(2024)Professional and Technical Staff supporting Open Research: Case Study 4. Research-enabling staff and Open Research. Other. OSF. UKRN Shared Resources.

2023

Skeldon, K. et al. (2023)Research Firsts Exhibition. (doi: 10.17605/OSF.IO/ZQC5P) [Exhibitions]

Keith, N. et al. (2023)Regenerative Futures: From Global to Local Development in 2032. (doi: 10.36399/gla.pubs.295862) [Exhibitions]

2022

Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580, Welisch, Gaston, Ross, Kirsty and Smykowski, Anja(2022)The Curious Researchers. [Website]

Evans, Jeff ORCID: https://orcid.org/0000-0002-4175-914X, Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580 and Paul, James ORCID: https://orcid.org/0000-0001-7367-5816(2022)An analysis of Relative Telomere Length (RTL) during peri-operative chemotherapy in patients with operable gastric or gastro-oesophageal junction adenocarcinoma. [Protocols]

Evans, Jeff ORCID: https://orcid.org/0000-0002-4175-914X, Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580 and Paul, James ORCID: https://orcid.org/0000-0001-7367-5816(2022)An analysis of Relative Telomere Length (RTL) during chemotherapy in patients with advanced gastro-oesophageal adenocarcinoma. [Protocols]

2021

Welisch, G. et al. (2021)First in Human: who and what makes a cancer phase 1 trial and why are they so important? Project Report. OSF.(doi: 10.17605/OSF.IO/KWHQF).

Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580, Plummer, Ruth, Coyle, Vicky, Cameron, David, Evans, Jeff ORCID: https://orcid.org/0000-0002-4175-914X, Twelves, Chris, Palmer, Dan, Danson, Sarah, Graham, Donna and Welisch, Gaston(2021)Early Phase Cancer Research in the COVID-19 Pandemic: an ECMC North Initiative. Project Report. OSF.(doi: 10.17605/OSF.IO/6WTN2).

2020

Ivanova, Yoana, Aitchison, Iain, Cannon, Paul ORCID: https://orcid.org/0000-0001-8721-1481, Butler, Darrell, Gadegaard, Nikolaj ORCID: https://orcid.org/0000-0002-3396-846X and Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580(2020)Mapping of University Research Output and Impact to the United Nations Sustainable Development Goals. Project Report. OSF.(doi: 10.17605/OSF.IO/UFYTA).

2019

Bilsland, Alan E. ORCID: https://orcid.org/0000-0003-0957-3908, Liu, Yu, Turnbull, Andrew, Sumpton, David, Stevenson, Katrina, Cairney, Claire J., Boyd, Susan M., Roffey, Jon, Jenkinson, David and Keith, W. Nicol ORCID: https://orcid.org/0000-0001-7862-3580(2019)A novel pyrazolopyrimidine ligand of human PGK1 and stress sensor DJ1 modulates the shelterin complex and telomere length regulation. Neoplasia, 21(9), pp. 893-907. (doi: 10.1016/j.neo.2019.07.008) (PMID:31401411) (PMCID:PMC6700475)

2018

Smit, Sharon, Kwakkel, Jaliene and Keith, Nicol ORCID: https://orcid.org/0000-0001-7862-3580(2018)Accomplissh: creating societal impact from social sciences and humanities research. In: Open Innovation 2.0 Yearbook 2017-2018. European Commission: Luxembourg, pp. 31-37. ISBN 9789279925856(doi: 10.2759/737501)

Keith, W. Nicol ORCID: https://orcid.org/0000-0001-7862-3580, Yu, Xinzi and Barbeau, Rose-Marie(2018)Diversity of institutional support for research impact implementation. Zeitschrift für Diversitätsforschung und –management, 3(2), pp. 199-207.

2017

Cairney, C. J. et al. (2017)A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds. PLoS Genetics, 13(8), e1006942. (doi: 10.1371/journal.pgen.1006942) (PMID:28806777) (PMCID:PMC5570495)

Letsolo, Boitelo T., Jones, Rhiannon E., Rowson, Jan, Grimstead, Julia W., Keith, W. Nicol ORCID: https://orcid.org/0000-0001-7862-3580, Jenkins, Gareth J.S. and Baird, Duncan M.(2017)Extensive telomere erosion is consistent with localised clonal expansions in Barrett's metaplasia. PLoS ONE, 12(3), e0174833. (doi: 10.1371/journal.pone.0174833) (PMID:28362812) (PMCID:PMC5375150)

2015

Amin, A.R.M. R. et al. (2015)Evasion of anti-growth signaling: a key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds. Seminars in Cancer Biology, 35, S55-S77. (doi: 10.1016/j.semcancer.2015.02.005) (PMID:25749195) (PMCID:PMC4561219)

Block, K. I. et al. (2015)Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars in Cancer Biology, 35, S276-S304. (doi: 10.1016/j.semcancer.2015.09.007) (PMID:26590477) (PMCID:PMC4819002)

Casey, S. C. et al. (2015)Cancer prevention and therapy through the modulation of the tumor microenvironment. Seminars in Cancer Biology, 35, S199-S223. (doi: 10.1016/j.semcancer.2015.02.007) (PMID:25865775) (PMCID:PMC4930000)

Feitelson, M. A. et al. (2015)Sustained proliferation in cancer: mechanisms and novel therapeutic targets. Seminars in Cancer Biology, 35(Suppl), S25-S54. (doi: 10.1016/j.semcancer.2015.02.006) (PMID:25892662) (PMCID:PMC4898971)

Ferguson, L. R. et al. (2015)Genomic instability in human cancer: molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. Seminars in Cancer Biology, 35(Suppl), S5-S24. (doi: 10.1016/j.semcancer.2015.03.005) (PMID:25869442) (PMCID:PMC4600419)

Jiang, W.G. et al. (2015)Tissue invasion and metastasis: Molecular, biological and clinical perspectives. Seminars in Cancer Biology, 35, S244-S275. (doi: 10.1016/j.semcancer.2015.03.008) (PMID:25865774)

Mohammad, R. M. et al. (2015)Broad targeting of resistance to apoptosis in cancer. Seminars in Cancer Biology, 35(Suppl.), S78-S103. (doi: 10.1016/j.semcancer.2015.03.001) (PMID:25936818)

Samadi, A. K. et al. (2015)A multi-targeted approach to suppress tumor-promoting inflammation. Seminars in Cancer Biology, 35(Suppl), S151-S184. (doi: 10.1016/j.semcancer.2015.03.006) (PMID:25951989) (PMCID:PMC4635070)

Vinay, D. S. et al. (2015)Immune evasion in cancer: mechanistic basis and therapeutic strategies. Seminars in Cancer Biology, 35(Suppl.), S185-S198. (doi: 10.1016/j.semcancer.2015.03.004) (PMID:25818339)

Wang, Z. et al. (2015)Broad targeting of angiogenesis for cancer prevention and therapy. Seminars in Cancer Biology, 35(Suppl.), S224-S243. (doi: 10.1016/j.semcancer.2015.01.001) (PMID:25600295) (PMCID:PMC4737670)

Yaswen, P. et al. (2015)Therapeutic targeting of replicative immortality. Seminars in Cancer Biology, 35(Supp.), S104-S128. (doi: 10.1016/j.semcancer.2015.03.007) (PMID:25869441) (PMCID:PMC4600408)

Sadaie, M., Dillon, C., Narita, M., Young, A.R.J., Cairney, C., Godwin, L.S., Torrance, C.J., Bennett, D.C., Keith, N. ORCID: https://orcid.org/0000-0001-7862-3580 and Narita, M.(2015)Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition. Molecular Biology of the Cell, 26(17), pp. 2971-2985. (doi: 10.1091/mbc.E15-01-0003) (PMID:26133385) (PMCID:PMC4551313)

Bilsland, A. E. et al. (2015)Identification of a selective G1-phase benzimidazolone inhibitor by a senescence-targeted virtual screen using artificial neural networks. Neoplasia, 17(9), pp. 704-715. (doi: 10.1016/j.neo.2015.08.009) (PMID:26476078) (PMCID:PMC4611071)

Hartmann, Daniel, von Figura, Guido, Song, Zhangfa, Harden, Sharon, Scott, Lucy C, Evans, TR Jeffry ORCID: https://orcid.org/0000-0002-4175-914X, Rudolph, Karl Lenhard, Bilsland, Alan E ORCID: https://orcid.org/0000-0003-0957-3908 and Keith, W Nicol ORCID: https://orcid.org/0000-0001-7862-3580(2015)PlasmaN-acetyl-glucosaminidase in advanced gastro-intestinal adenocarcinoma correlates with age, stage and outcome. Future Oncology, 11(2), pp. 193-203. (doi: 10.2217/fon.14.166)

2014

Degerman, S. et al. (2014)Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias. Neoplasia, 16(7), pp. 606-615. (doi: 10.1016/j.neo.2014.07.001)

Bilsland, Alan E. ORCID: https://orcid.org/0000-0003-0957-3908, Stevenson, Katrina, Liu, Yu, Hoare, Stacey, Cairney, Claire J., Roffey, Jon and Keith, W. Nicol ORCID: https://orcid.org/0000-0001-7862-3580(2014)Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms. PLoS Computational Biology, 10(2), e1003448. (doi: 10.1371/journal.pcbi.1003448) (PMID:24550717) (PMCID:PMC3923661)

Godwin, Lauren S., Castle, Joanna T., Kohli, Jaskaren S., Goff, Philip S., Cairney, Claire J., Keith, W. Nicol ORCID: https://orcid.org/0000-0001-7862-3580, Sviderskaya, Elena V. and Bennett, Dorothy C.(2014)Isolation, culture, and transfection of melanocytes. In: Current Protocols in Cell Biology. Wiley-Blackwell, 1.8.1-1.8.20. ISBN 9780471143031(doi: 10.1002/0471143030.cb0108s63)

2013

Bilsland, Alan E. ORCID: https://orcid.org/0000-0003-0957-3908, Revie, John and Keith, W.Nicol ORCID: https://orcid.org/0000-0001-7862-3580(2013)MicroRNA and senescence: the senectome, integration and distributed control. Critical Reviews in Oncogenesis, 18(4), pp. 373-390. (doi: 10.1615/CritRevOncog.2013007197)

2012

Mohanty, S.T. et al. (2012)A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice. Stem Cells, 30(6), pp. 1134-43. (doi: 10.1002/stem.1065)

Venturini, L., Daidone, M.G., Motta, R., Cimino-Reale, G., Hoare, S.F., Gronchi, A., Folini, M., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Zaffaroni, N.(2012)Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance. Neuro-Oncology, 14(6), pp. 736-744. (doi: 10.1093/neuonc/nos083)

Cairney, C.J., Bilsland, A.E. ORCID: https://orcid.org/0000-0003-0957-3908, Evans, T.R.J. ORCID: https://orcid.org/0000-0002-4175-914X, Roffey, J., Bennett, D.C., Narita, M., Torrance, C. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2012)Cancer cell senescence: a new frontier in drug development. Drug Discovery Today, 17(5-6), pp. 269-276. (doi: 10.1016/j.drudis.2012.01.019)

Bellantuono, I., Sanguinetti, G. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2012)Progeroid syndromes: models for stem cell aging? Biogerontology, 13(1), pp. 63-75. (doi: 10.1007/s10522-011-9347-2)

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Lafferty-Whyte, K, Cairney, C.J., Zaffaroni, N. and Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908(2012)Response to ‘Validating a gene expression signature proposed to differentiate liposarcomas that use different telomere maintenance mechanism. Oncogene, 31(2), pp. 267-268. (doi: 10.1038/onc.2011.374)

2011

Bilsland, A.E. ORCID: https://orcid.org/0000-0003-0957-3908, Cairney, C.J. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2011)Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives. Journal of Cellular and Molecular Medicine, 15(2), pp. 179-186. (doi: 10.1111/j.1582-4934.2010.01253.x)

Serakinci, N., Christensen, R., Fahrioglu, U., Sorensen, F.B., Dagnæs-Hansen, F., Hajek, M., Jensen, T.H., Kolvraa, S. and Keith, N.W. ORCID: https://orcid.org/0000-0001-7862-3580(2011)Mesenchymal stem cells as therapeutic delivery vehicles targeting tumor stroma. Cancer Biotherapy and Radiopharmaceuticals, 26(6), pp. 767-773. (doi: 10.1089/cbr.2011.1024)

Soo, J.K. et al. (2011)Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression. Pigment Cell and Melanoma Research, 24(3), pp. 490-503. (doi: 10.1111/j.1755-148X.2011.00850.x)

2010

Lafferty-Whyte, K., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Hoare, S.F., Burns, S., Zaffaroni, N., Cairney, C.J. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2010)TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression. Neoplasia, 12(5), pp. 405-414.

Degerman, S., Siwicki, J. K., Osterman, P., Lafferty-Whyte, K., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Roos, G.(2010)Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures. Aging Cell, 9(2), pp. 220-235. (doi: 10.1111/j.1474-9726.2010.00550.x)

Bilsland, Alan. E. ORCID: https://orcid.org/0000-0003-0957-3908 and Keith, W. Nicol ORCID: https://orcid.org/0000-0001-7862-3580(2010)Mining cellular senescence for drug targets. In: Adams, Peter. D. and Sedivy, John M. (eds.)Cellular Senescence and Tumor Suppression. Springer: New York, pp. 235-266. ISBN 9781441910745(doi: 10.1007/978-1-4419-1075-2_10)

Lafferty-Whyte, K. et al. (2010)Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma. BMC Genomics, 11(1), p. 532. (doi: 10.1186/1471-2164-11-532)

Stolzenburg, S., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Rots, M.G.(2010)Modulation of gene expression using zinc finger-based artificial transcription factors. Methods in Molecular Biology, 649(2), pp. 117-132. (doi: 10.1007/978-1-60761-753-2_7)

2009

Lafferty-Whyte, K., Cairney, C.J., Will, M.B., Serakinci, N., Daidone, M.G., Zaffaroni, N., Bilsland, A.E. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2009)A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT. Oncogene, 28(43), pp. 3765-3774. (doi: 10.1038/onc.2009.238)

Sitaram, R.T., Cairney, C.J., Grabowski, P., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Hallberg, B., Ljungberg, B. and Roos, G.(2009)The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma. International Journal of Cancer, 125(4), pp. 783-790. (doi: 10.1002/ijc.24335)

Bilsland, A.E., Hoare, S.F., Stevenson, K.H., Plumb, J.A., Gomez-Roman, N. ORCID: https://orcid.org/0000-0002-2325-7517, Cairney, C.J., Burns, S., Lafferty-Whyte, K., Hammonds, T. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2009)Dynamic telomerase gene suppression via network effects of GSK3 inhibition. PLoS ONE, 4(7), e6459. (doi: 10.1371/journal.pone.0006459) (PMID:19649288) (PMCID:PMC2714081)

Cairney, C.J., Sanguinetti, G., Ranghini, E., Chantry, A.D., Nostro, M.C., Bhattacharyya, A., Svendsen, C.N., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Bellantuono, I.(2009)A systems biology approach to Down syndrome: Identification of Notch/Wnt dysregulation in a model of stem cells aging. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1792(4), pp. 353-363. (doi: 10.1016/j.bbadis.2009.01.015)

Lafferty-Whyte, K., Cairney, C.J., Jamieson, N., Oien, K.A. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2009)Pathway analysis of senescence-associated miRNA targets reveals common processes to different senescence induction mechanisms. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1792(4), pp. 341-352. (doi: 10.1016/j.bbadis.2009.02.003)

Shay, J. and Keith, N. ORCID: https://orcid.org/0000-0001-7862-3580(2009)Cellular immortality and cancer: From telomerase to cancer stem cells Preface. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1792(4), pp. 227-228. (doi: 10.1016/j.bbadis.2009.03.006)

Zhang, X. et al. (2009)A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. Journal of Cell Biology, 184(1), pp. 67-82. (doi: 10.1083/jcb.200801009)

2008

Stewart, R., Yang, C., Anyfantis, G., Przyborski, S., Hole, N., Strachan, T., Stojkovic, M., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Armstrong, L. and Lako, M.(2008)Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells. Regenerative Medicine, 3(4), pp. 505-522. (doi: 10.2217/17460751.3.4.505)

Cairney, CJ, Hoare, SF, Daidone, MG, Zaffaroni, N and Keith, WN ORCID: https://orcid.org/0000-0001-7862-3580(2008)High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma. British Journal of Cancer, 98(8), pp. 1467-1474. (doi: 10.1038/sj.bjc.6604328)

Saretzki, G. et al. (2008)Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells. Stem Cells, 26(2), pp. 455-464. (doi: 10.1634/stemcells.2007-0628)

Shay, J W and Keith, W N ORCID: https://orcid.org/0000-0001-7862-3580(2008)Targeting telomerase for cancer therapeutics. British Journal of Cancer, 98(4), pp. 677-683. (doi: 10.1038/sj.bjc.6604209)

Cairney, CJ and Keith, WN ORCID: https://orcid.org/0000-0001-7862-3580(2008)Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity. Biochimie, 90(1), pp. 13-23. (doi: 10.1016/j.biochi.2007.07.025)

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Bilsland, A.E.(2008)Targeting telomerase: therapeutic options for cancer treatment. In: Rudolph, K.L. (ed.)Telomeres and Telomerase in Aging, Disease, and Cancer: Molecular Mechanisms of Adult Stem Cell Ageing. Springer: Berlin, Germany, pp. 247-283. ISBN 9783540737087(doi: 10.1007/978-3-540-73709-4_13)

2007

Atkinson, S.P. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2007)Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention. Expert Reviews in Molecular Medicine, 9(7), pp. 1-26. (doi: 10.1017/S1462399407000269)

Bellantuono, I. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2007)Stem cell ageing: does it happen and can we intervene? Expert Reviews in Molecular Medicine, 9(31), pp. 1-20. (doi: 10.1017/S146239940700049X)

Bilsland, A.E. ORCID: https://orcid.org/0000-0003-0957-3908, Merron, A., Vassaux, G. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2007)Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses. Cancer Research, 67(3), pp. 1299-1307. (doi: 10.1158/0008-5472.CAN-06-3000)

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Thomson, C.M., Howcroft, J., Maitland, N.J. and Shay, J.W.(2007)Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells. Drug Discovery Today, 12, pp. 611-621.

Serakinci, N., Christensen, R., Graakjaer, J., Cairney, C.J., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Alsner, J., Saretzki, G. and Koluraa, S.(2007)Ectopically hTERT expressing adult human mesenchymal stem cells are less radiosensitive than their telomerase negative counterpart. Experimental Cell Research, 313, pp. 1056-1067. (doi: 10.1016/j.yexcr.2007.01.002)

2006

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2006)European Journal of Cancer Special Issue on Cancer Stem Cells: Opportunities for Novel Diagnostics and Drug Discovery. European Journal of Cancer, 42(9), pp. 1195-1316. (doi: 10.1016/j.ejca.2006.02.003)

Anderson, C.J., Hoare, S.F., Ashcroft, M., Bilsland, A.E. ORCID: https://orcid.org/0000-0003-0957-3908 and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2006)Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms. Oncogene, 25(1), pp. 61-69. (doi: 10.1038/sj.onc.1209011)

Bilsland, AE, Stevenson, K, Atkinson, S, Kolch, W and Keith, WN ORCID: https://orcid.org/0000-0001-7862-3580(2006)Transcriptional repression of telomerase RNA gene expression by c-Jun-NH2-kinase and Sp1/Sp3. Cancer Research, 66(3), pp. 1363-1370. (doi: 10.1158/0008-5472.CAN-05-1941)

Serakinci, N., Hoare, S.F., Kassem, M., Atkinson, S.P. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2006)Telomerase promoter reprogramming and interaction with general transcription factors in the human mesenchymal stem cell. Regenerative Medicine, 1(1), pp. 125-131. (doi: 10.2217/17460781.1.1.125)

Serakinci, N. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2006)Therapeutic potential of adult stem cells. European Journal of Cancer, 42(9), pp. 1243-1246. (doi: 10.1016/j.ejca.2006.01.036)

2005

Zhao, J., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Jackson, K. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2005)MDM2 negatively regulates the human telomerase RNA gene promoter. BMC Cancer, 5, 6. (doi: 10.1186/1471-2407-5-6) (PMID:15656906) (PMCID:PMC546012)

Atkinson, S.P., Hoare, S.F., Glasspool, R.M. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2005)Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters. Cancer Research, 65(17), pp. 7585-7590. (doi: 10.1158/0008-5472.CAN-05-1715)

Bilsland, A.E. ORCID: https://orcid.org/0000-0003-0957-3908, Fletcher-Monaghan, A. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2005)Properties of a telomerase-specific Cre/Lox switch for transcriptionally targeted cancer gene therapy. Neoplasia, 7(11), pp. 1020-1029. (doi: 10.1593/neo.05385)

Dennis, J. et al. (2005)Markers of adenocarcinoma characteristic of the site of origin: Development of a diagnostic algorithm. Clinical Cancer Research, 11(10), pp. 3766-3772.

Drummond, M.W., Hoare, S.F., Monaghan, A., Graham, S.M., Alcorn, M.J., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Holyoake, T.L.(2005)Dysregulated expression of the major telomerase components in leukaemic stem cells. Leukemia, 19(3), pp. 381-389. (doi: 10.1038/sj.leu.2403616)

Dufes, C., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Proutski, I., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Uchegbu, I.F. and Schõtzlein, A.G.(2005)Synthetic anti-cancer gene medicine exploits intrinsic anti-tumour activity of cationic vector to cure established tumours. Cancer Research, 65(18), pp. 8079-8084. (doi: 10.1158/0008-5472.CAN-04-4402)

Fullerton, NE, Mairs, RJ, Kirk, D, Keith, WN ORCID: https://orcid.org/0000-0001-7862-3580, Carruthers, R, McCluskey, AG, Brown, M, Wilson, L and Boyd, M(2005)Application of targeted radiotherapy/gene therapy to bladder cancer cell lines. European Urology, 47(2), pp. 250-256. (doi: 10.1016/j.eururo.2004.09.009)

Glasspool, R.M., Burns, S., Hoare, S.F., Svensson, C. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2005)The hTERT and hTERC telomerase gene promoters are activated by the second Exon of the adenoviral protein, E1A, identifying the transcriptional co-repressor CtBP as a potential repressor of both genes. Neoplasia, 7(6), pp. 614-622. (doi: 10.1593/neo.04766)

Westra, J. et al. (2005)Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase protein expression on survival in adjuvantly treated stage III colon cancer patients. Annals of Oncology, 16(10), pp. 1646-1653. (doi: 10.1093/annonc/mdi316)

2004

Boyd, M. et al. (2004)An efficient targeted radiotherapy/gene therapy strategy utilising human telomerase promoters and radioastatine and harnessing radiation-mediated bystander effects. Journal of Gene Medicine, 6(8), pp. 937-947. (doi: 10.1002/jgm.578)

Evans, T.R.J. ORCID: https://orcid.org/0000-0002-4175-914X and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2004)Intra-Peritoneal Administration of Genetic Therapies: promises and pitfalls. Minerva Ginecologica, 56(6), pp. 529-538.

Fullerton, N.E., Boyd, M., Mairs, R.J. ORCID: https://orcid.org/0000-0001-6843-3900, Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Alderwish, O., Brown, M.M., Livingstone, A. and Kirk, D.(2004)Combining a targeted radiotherapy and gene therapy approach for adenocarcinoma of prostate. Prostate Cancer and Prostatic Diseases, 7(4), pp. 355-363. (doi: 10.1038/sj.pcan.4500760)

Going, J.J., Fletcher-Monaghan, A.J., Neilson, L., Wisman, B.A., van der Zee, A., Stuart, R.C. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2004)Zoning of mucosal phenotype, dysplasia, and telomerase activity measured by telomerase repeat assay protocol in Barrett's esophagus. Neoplasia, 6(1), pp. 85-92.

Groot-Wassink, T., Aboagye, E.O., Wang, Y.H., Lemoine, N.R., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Vassaux, G.(2004)Noninvasive imaging of the transcriptional activities of human telomerase promoter fragments in mice. Cancer Research, 64(14), pp. 4906-4911.

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2004)From stem cells to cancer: balancing immortality and neoplasia. Oncogene, 23(29), pp. 5092-5094. (doi: 10.1038/sj.onc.1207762)

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Hoare, S.F.(2004)Detection of telomerase hTERT gene expression and its splice variants by RT-PCR. In: Roulston, J.E. and Bartlett, J.M.S. (eds.)Molecular Diagnosis of Cancer: Methods and Protocols. Series: Methods in molecular medicine (97). Humana Press: Totowa, NJ, USA, pp. 297-309. ISBN 9781588291608

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Monaghan, A.J.(2004)Detection of telomerase enzyme activity by TRAP assay. In: Roulston, J.E. and Bartlett, J.M.S. (eds.)Molecular Diagnosis of Cancer: Methods and Protocols. Series: Methods in molecular medicine (97). Humana Press: Totowa, NJ, USA, pp. 311-322. ISBN 9781588291608

Keith, W.N. et al. (2004)A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria. BMC Blood Disorders, 4(3), (doi: 10.1186/1471-2326-4-3)

Keith, WN ORCID: https://orcid.org/0000-0001-7862-3580, Bilsland, A ORCID: https://orcid.org/0000-0003-0957-3908, Hardie, M and Evans, TRJ ORCID: https://orcid.org/0000-0002-4175-914X(2004)Drug Insight: cancer cell immortality - telomerase as a target for novel cancer gene therapies. Nature Clinical Practice Oncology, 1(2), pp. 88-96. (doi: 10.1038/ncponc0044)

Oien, K.A. ORCID: https://orcid.org/0000-0002-5237-275X, McGregor, F., Butler, S., Ferrier, R.K., Downie, I., Bryce, S., Burns, S. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2004)Gastrokine 1 is abundantly and specifically expressed in superficial gastric epithelium, down-regulated in gastric carcinoma, and shows high evolutionary conservation. Journal of Pathology, 203(3), pp. 789-797. (doi: 10.1002/path.1583)

2003

Keith, N. ORCID: https://orcid.org/0000-0001-7862-3580 and Bagnis, C.(2003)Why a Special Issue on Gene Therapy? Journal of Biomedicine and Biotechnology, 2003(1), pp. 1-2. (doi: 10.1155/S1110724303003000)

Bilsland, A.E. ORCID: https://orcid.org/0000-0003-0957-3908, Anderson, C.J., Fletcher-Monaghan, A.J., McGregor, F., Evans, T.R.J. ORCID: https://orcid.org/0000-0002-4175-914X, Ganly, I., Knox, R.J., Plumb, J.A. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2003)Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase. Oncogene, 22(3), pp. 370-380. (doi: 10.1038/sj.onc.1206168)

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2003)In situ analysis of telomerase RNA gene expression as a marker for tumor progression. In: Driscoll, B. (ed.)Lung Cancer. Series: Methods in Molecular Medicine, Volume (75. II). Humana Press: Totowa, NJ, USA, pp. 163-176. ISBN 9780896039209(doi: 10.1385/1-59259-324-0:163)

Oien, K.A. ORCID: https://orcid.org/0000-0002-5237-275X, Vass, J.K., Downie, I., Fullarton, G. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2003)Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomach. Oncogene, 22(27), pp. 4287-4300. (doi: 10.1038/sj.onc.1206615)

Zhao, J.Q., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Hoare, S.F. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2003)Involvement of NF-Y and Sp1 binding sequences in basal transcription of the human telomerase RNA gene. FEBS Letters, 536(1-3), pp. 111-119. (doi: 10.1016/S0014-5793(03)00038-3)

2002

Dennis, J.L., Vass, J.K., Wit, E.C., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Oien, K.A. ORCID: https://orcid.org/0000-0002-5237-275X(2002)Identification from public data of molecular markers of adenocarcinoma characteristic of the site of origin. Cancer Research, 62(21), pp. 5999-6005.

Evans, TR and Keith, WN ORCID: https://orcid.org/0000-0001-7862-3580(2002)Telomerase and the senescence-like phenotype in cancer progression. Gastrointestinal Cancer Abstracts, 8, pp. 2-5.

Going, J.J., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Neilson, L., Stoeber, K., Stuart, R.C. and Williams, G.H.(2002)Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and Barrett's mucosa. Gut, 50(3), pp. 373-377. (doi: 10.1136/gut.50.3.373)

Going, J.J., Stuart, R.C., Downie, M., Fletcher-Monaghan, A.J. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2002)'Senescence-associated' beta-galactosidase activity in the upper gastrointestinal tract. Journal of Pathology, 196(4), pp. 394-400. (doi: 10.1002/path.1059)

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2002)Molecular biology techniques. In: Cassidy, J., Bisset, D. and Spence, R. (eds.)Oxford Handbook of Oncology. Oxford University Press: Oxford, UK, pp. 15-20. ISBN 9780192630353

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Evans, T.R.J. ORCID: https://orcid.org/0000-0002-4175-914X and Glasspool, R.M.(2002)Telomerase-Directed Molecular Therapeutics. Expert Reviews in Molecular Medicine(4), pp. 1-25. (doi: 10.1017/S1462399402004507)

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Sarvesvaran, J. and Downey, M.(2002)Analysis of telomerase RNA gene expression by in situ hybridization. Methods in Molecular Biology, 191, pp. 65-81. (doi: 10.1385/1-59259-189-2:65)

2001

Boyd, M., Mairs, R.J. ORCID: https://orcid.org/0000-0001-6843-3900, Mairs, S.C., Wilson, L., Livingstone, A., Cunningham, S.H., Brown, M.M., Quigg, M. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2001)Expression in UVW glioma cells of the noradrenaline transporter gene, driven by the telomerase RNA promoter, induces active uptake of [I-131]MIBG and clonogenic cell kill. Oncogene, 20(53), pp. 7804-7808.

Downey, M.G., Going, J.J., Stuart, R.C. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2001)Expression of telomerase RNA in oesophageal and oral cancer. Journal of Oral Pathology and Medicine, 30(10), pp. 577-581. (doi: 10.1034/j.1600-0714.2001.301001.x)

Hoare, S.F., Bryce, L.A., Wisman, G.B.A., Burns, S., Going, J.J., van der Zee, A.G.J. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2001)Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter. Cancer Research, 61(1), pp. 27-32.

Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Evans, T.R.J. ORCID: https://orcid.org/0000-0002-4175-914X and Glasspool, R.M.(2001)Telomerase and cancer: time to move from a promising target to a clinical reality. Journal of Pathology, 195(4), pp. 404-414. (doi: 10.1002/path.1001)

Plumb, J.A., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Kakani, R., Zhao, J.Q., Glasspool, R.M., Knox, R.J., Evans, T.R.J. ORCID: https://orcid.org/0000-0002-4175-914X and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2001)Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954. Oncogene, 20(53), pp. 7797-7803.

2000

Bryce, L.A., Morrison, N., Hoare, S.F., Muir, S. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2000)Mapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridization. Neoplasia, 2(3), pp. 197-201.

Wisman, G.B.A., De Jong, S., Meersma, G.J., Helder, M.N., Hollema, H., de Vries, E.G.E., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and van der Zee, A.G.J.(2000)Telomerase in (pre)neoplastic cervical disease. Human Pathology, 31(10), pp. 1304-1312. (doi: 10.1053/hupa.2000.19299)

Zhao, J.Q., Glasspool, R.M., Hoare, S.F., Bilsland, A. ORCID: https://orcid.org/0000-0003-0957-3908, Szatmari, I. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(2000)Activation of telomerase RNA gene promoter activity by NF-Y, Sp1, and the retinoblastoma protein and repression by Sp3. Neoplasia, 2(6), pp. 531-539.

1999

Agochiya, M., Brunton, V.G., Owens, D.W., Parkinson, E.K., Paraskeva, C., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Frame, M.C.(1999)Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells. Oncogene, 18(41), pp. 5646-5653.

Al Mulla, F., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Pickford, I.R., Going, J.J. and Birnie, G.D.(1999)Comparative genomic hybridization analysis of primary colorectal carcinomas and their synchronous metastases. Genes, Chromosomes and Cancer, 24(4), pp. 306-314.

Russell, A.J., Sibbald, J., Haak, H., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and McNicol, A.M.(1999)Increasing genome instability in adrenocortical carcinoma progression with involvement of chromosomes 3, 9 and X at the adenoma stage. British Journal of Cancer, 81(4), pp. 684-689. (doi: 10.1038/sj.bjc.6690748)

Sarvesvaran, J., Going, J.J., Milroy, R., Kaye, S.B. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(1999)Is small cell lung cancer the perfect target for anti- telomerase treatment? Carcinogenesis, 20(8), pp. 1649-1651. (doi: 10.1093/carcin/20.8.1649)

1998

Soder, A.I., Going, J.J., Kaye, S.B. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(1998)Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization. Oncogene, 16(8), pp. 979-983.

Zhao, J.Q., Hoare, S.F., McFarlane, R., Muir, S., Parkinson, E.K., Black, D.M. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(1998)Cloning and characterization of human and mouse telomerase RNA gene promoter sequences. Oncogene, 16(10), pp. 1345-1350.

1997

Gause, P.R., LluriaPrevatt, M., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580, Balmain, A., Linardopolous, S., Warneke, J. and Powell, M.B.(1997)Chromosomal and genetic alterations of 7,12- dimethylbenz[a]anthracene-induced melanoma from TP-ras transgenic mice. Molecular Carcinogenesis, 20(1), pp. 78-87.

Hoare, S.F., Freeman, C.A., Coutts, J.C., Varley, J.M., James, L. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(1997)Identification of genetic changes associated with drug resistance by reverse in situ hybridization. British Journal of Cancer, 75(2), pp. 275-282.

Mckay, J.A., Murray, G.I., Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580 and Mcleod, H.L.(1997)Amplification of fluorescent in situ hybridisation signals in formalin fixed paraffin wax embedded sections of colon tumour using biotinylated tyramide. Journal of Clinical Pathology, 50(6), pp. 322-325.

Parkinson, E.K., Newbold, R.F. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(1997)The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: The role of telomerase reactivation. European Journal of Cancer, 33(5), pp. 727-734. (doi: 10.1016/S0959-8049(97)00063-4)

Soder, A.I., Hoare, S.F., Muir, S., Going, J.J., Parkinson, E.K. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(1997)Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer. Oncogene, 14(9), pp. 1013-1021.

Soder, A.I., Hoare, S.F., Muire, S., Balmain, A., Parkinson, E.K. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(1997)Mapping of the gene for the mouse telomerase RNA component, Terc, to chromosome 3 by fluorescence in situ hybridization and mouse chromosome painting. Genomics, 41(2), pp. 293-294. (doi: 10.1006/geno.1997.4621)

1994

van der Zee, A.G.J., de Vries, E.G.E., Hollema, H., Kaye, S.B., Brown, R. and Keith, W.N. ORCID: https://orcid.org/0000-0001-7862-3580(1994)Molecular analysis of the topoisomerase II α gene and its expression in human ovarian cancer. Annals of Oncology, 5(1), pp. 75-81. (doi: 10.1093/oxfordjournals.annonc.a058700) (PMID:8172796)

This list was generated on Mon Feb 16 23:48:40 2026 GMT.