ilana brin | Hadassah-Hebrew University Medical Center (original) (raw)
Papers by ilana brin
British journal of orthodontics, Aug 1, 1997
The prevalence of occlusal features in 939 children, aged 6-13 years, belonging to an ultra-ortho... more The prevalence of occlusal features in 939 children, aged 6-13 years, belonging to an ultra-orthodox community of Jewish Ashkenazi descent living in Jerusalem was studied clinically. Sexual dimorphism was found for overjet, overbite, and habit practising. About one-quarter of the sample exhibited some degree of occlusal mutilation due to caries, thus creating a 'caries-affected' subgroup, the rest forming the 'caries-free' subgroup. In the latter set, normocclusion was scarce (7.4 per cent), Class I being the most frequent malocclusion (49.1 per cent). Caries had a significant effect on the symmetry of bilateral occlusal relationships, lower dental midline deviation, and on crowding/spacing conditions in the mixed dentition stage (except for the maxilla in late mixed dentition). The low prevalence of normocclusion can be attributed to genetic background, environmental influences and the definition attached to normal occlusion.
PubMed, Sep 1, 1991
The effect of premature extractions of primary molars on further development of their successors ... more The effect of premature extractions of primary molars on further development of their successors was studied. A group of forty-six children with fifty-three unilaterally extracted mandibular primary molars was examined when the successors completed their root development. Radiographs of the successors to the extracted molars and their antimeres, which served as internal controls, were taken using the long-cone technique. Crown and root length and area in cross-section, were measured from tracings of the studied teeth and crown/root ratios were calculated. Significantly (p less than 0.05) larger area ratio in the extraction group was found suggesting a smaller root area. In addition, root foreshortening for the first premolars and diminished root area for the second premolars, both successors to teeth extracted after the age of eight years, were found. Although statistically significant, all of the differences were of no clinical importance.
PubMed, 1989
Lower face height indicators and mandibular rotation are assessed at 7 and 12 years of age in a s... more Lower face height indicators and mandibular rotation are assessed at 7 and 12 years of age in a sample of 46 children, comparing the corpus axis and mandibular plane as indicators of change in mandibular position. The parameters involving the mandibular plane consistently show higher correlations.
American Journal of Orthodontics, Feb 1, 1981
Previous experiments indicate that bone cells respond to externally applied stimuli with jhtctuat... more Previous experiments indicate that bone cells respond to externally applied stimuli with jhtctuations of cyclic nucleotide levels. The objective of this experiment was to study the response of bone at the midpalatal suture to the application of tensile forces in young and old animals, through an examination of the osteoblastic staining pattern jor CAMP and cGMP. The midpalatal suture was rapidly expanded for 0, 10, and 15 days, respectively, in three young and three old cats. Fresh, ,frozen, unhxed, undecalcij5ed maxillae were sectioned transversely and stained immunohistochemically for CAMP and cGMP. The staining intensity for both nucleotides was increased in the osteoblasts of the young treated animals, while in the old animals the osteoblasts were only faintly stained for CAMP and cGMP. These results demonstrate that bone cells of old animals are less responsive to tensile jorces than the corresponding cells in young animals.
Dental Traumatology, Jun 1, 2000
Increased overjet and inadequate lip coverage of the maxillary incisors are considered significan... more Increased overjet and inadequate lip coverage of the maxillary incisors are considered significant risk factors in many clinical studies. The purpose of the present study was to examine this issue of dental injury by actual cephalometric measurements in orthodontic patients. Pretreatment cephalograms (taken with lips in repose) of consecutive patients were used. The patients were allotted to two groups Group T (trauma): 56 patients who had injured their maxillary incisors prior to their orthodontic treatment, mean age at the start of treatment 11.9 years (SD = 1.5); and Group C (control): 98 patients with intact maxillary incisors, mean age at the start of treatment 11.6 years (SD = 1.3). Twelve cephalometric landmarks on the soft and hard tissue profile were identified and digitized and the relevant dental, skeletal and soft tissue measurements recorded. The variables in Groups T and C were compared and their predictive values for possible occurrence of trauma were tested by logistic regression analysis. No statistically significant differences between boys and girls were found. Overjet or maxillary incisor exposure or interlabial gap, each as a single variable, could differentiate between the two groups. Logistic regression analysis indicated that only a small percentage (28.7%) of the dependent variable variation (trauma vs control) can be explained by interlabial gap, gender, upper incisor long axis to facial plane (degree), upper incisor long axis to interlabial gap and overjet.
American Journal of Orthodontics, May 1, 1982
American Journal of Orthodontics and Dentofacial Orthopedics, Nov 1, 1992
Knowledge of the normal dentofacial patterns of various ethnic groups is important for clinical a... more Knowledge of the normal dentofacial patterns of various ethnic groups is important for clinical and research purposes. The objective of this study was to describe the dentofacial pattern of one Jewish ethnic group and to compare it with accepted standards for other white populations. Lateral cephalometric radiographs of 18 children of Jewish East European origin with clinically acceptable permanent occlusion, ages 11 to 13 years, were used. A computer-aided cephalometric analysis was performed, and the mean values and standard deviations for the various cephalometric variables were obtained. When compared with some classical standards, it was found that this ethnic group tended toward a mild skeletal Class II, a convex profile, and a more vertical direction of growth. These features appeared in persons selected on the basis of a clinically acceptable occlusion, suggesting the existence of dental compensations. Understanding these natural accommodations of the dentition to skeletal variations can be clinically useful when establishing treatment goals. (AM J ORTHOD DENTOFAC ORTHOP 1992;102:443-8.) Cephalometric characteristics of various races and ethnic groups have been presented by several researchers t7 as this knowledge is important for clinical and research purposes. The present study is a survey of the skeletal and dental patterns of Jewish adolescents of East European origin who have normal occlusion, cephalometric analysis being the method used. The dispersal of the Jews from Ancient Palestine resulted in the foundation of Jewish communities throughout the world. At the end of the 18th century, the Jews began to return to Israel in waves, which reached a climax after the establishment of the state in 1948. In the Middle Ages, the Jews from Central and Eastern Europe were referred to as Ashkenazi Jews. They comprise one of the largest Jewish ethnic groups. Our objective is to describe the characteristic cephalometric dentofacial pattern of a sample of this ethnic group, and in addition, to document the differences between this sample and some American white samples. MATERIALS AND METHODS The data base for this report originates from the material collected in 1969 to 1971 for a growth study of seven ethnic
The Cleft Palate-Craniofacial Journal, Mar 1, 1992
International Journal of Anthropology, 1996
Archives of Oral Biology, Oct 1, 2001
The periodontal vasculature encircling the entire length of the rat lower incisor was studied at ... more The periodontal vasculature encircling the entire length of the rat lower incisor was studied at the time of tipping movement and 3 months later. In 12 rats (212+/-4 g b.w.), loads (0.19+/-0.016 N) were applied to the lower left incisor in a linguointrusive direction. After 2 weeks of loading, six experimental animals were killed with the loading springs in place. The springs were removed in the six remaining rats, which were killed 12 weeks later. Six additional rats with intact teeth served as control. All incisors were fixed, demineralized, embedded in glycol methacrylate and cross-sectioned perpendicular to the long axis of the tooth. The distance of each section (2 microm) from the apex was calculated. A computerized image-analysis program was used to measure the width and area of the labial and lingual periodontal ligament to establish whether the measured segments corresponded to the compressed or expanded zones. In each cross-section, the various types of blood vessels were counted and the cross-sectional area of all venous vessels was measured. The results showed that after 2 weeks of loading (1) the general trend of vascular changes was similar under pressure and tension; (2) the large-diameter vessels were unaffected by loading; (3) the mean number of terminal arterioles had decreased significantly, while the number of capillaries and postcapillary venules had increased significantly in the apical tooth part; (4) the venous blood vessel area had decreased significantly in the apical tooth part; (5) the intensity of the vascular reaction was dependent on the degree of tissue distortion; and (6) after 12 weeks' recovery the vascular changes were still present, demonstrating a rebound effect. The findings suggest that microvascular alterations following tooth loading are not directly related to the spatial effect of loading itself and are of a much longer duration than expected.
Journal of Dental Education, Dec 1, 1990
International Journal of Osteoarchaeology
Malocclusion is a well‐known phenomenon since antiquity. Previous studies found an increase in ma... more Malocclusion is a well‐known phenomenon since antiquity. Previous studies found an increase in malocclusion in the modern population. This study was undertaken to assess the frequency and severity of malocclusions in a sample of ancient skulls and to compare these findings with a modern sample, using the same examination protocol. The archaeological sample comprised 63 skulls from Dor, northern Israel, dated to the 16th–19th centuries. Skull examination was performed in maximal occlusion by using a clinically based approach. The modern sample comprised a random, ethnicity‐matched group of 340 school students, aged 11–16 years, who underwent a clinical orthodontic examination. The following parameters were recorded for both groups: Angle's classification, overjet, overbite, crowding, spacing, midlines, and crossbite. Descriptive statistics was obtained for all the parameters examined, and the results were compared between the groups. Differences were considered significant at p &...
Journal of clinical orthodontics, Sep 1, 1984
Journal of clinical orthodontics : JCO, 1985
Pediatric dentistry, 1985
This clinical and radiographic investigation was undertaken in an attempt to correlate the develo... more This clinical and radiographic investigation was undertaken in an attempt to correlate the developmental stage of the permanent tooth buds, the chronological age at the time of trauma, and the degree of primary root resorption with mineralization defects in the permanent Successors. One hundred children who had experienced trauma to their primary incisors were recalled and their immediate posttrauma radiographs were examined. Sixty-four exhibited possible signs of previously unnoticed and unreported trauma and were eliminated from the study. This high percentage of unnoticed injury indicates the need for careful radiographic examination to discover signs of previous trauma when attempting to correlate developmental disturbances with injury to primary incisors. Discoloration of the crown of the permanent tooth was evident in 16% of the children with the incisal one-third being the most common site. Hypoplasia was evident in 9% of the permanent teeth. No association could be established between the amount of primary root resorption and the appearance of mineralization defects on the permanent successors. Correlation between trauma to the primary teeth and the presence of mineralization defects in the permanent dentition has been described previously.
Pediatric dentistry, 1984
One hundred and twenty-four children who had experienced trauma to their primary incisors were in... more One hundred and twenty-four children who had experienced trauma to their primary incisors were included in this clinical investigation in an attempt to correlate the type of injury occurring to the primary teeth, the age of the patient at the time of trauma with mineralization defects, and intra- and interarch relationships of the permanent incisors. Thirty-four per cent of the
Pediatric dentistry, 1986
Trauma to the primary incisors may, by their displacement, cause developmental disturbances in th... more Trauma to the primary incisors may, by their displacement, cause developmental disturbances in the root formation of the permanent incisors. To verify this hypothesis, dental radiographs of 34 children, whose primary incisors had been previously injured, were evaluated. Only 6 children showed disturbances in root development of maxillary permanent incisors. Three cases in which trauma to the primary dentition resulted in pathology to the permanent dentition are presented, stressing the need for close periodic examination and early detection of possible developmental defects in the permanent dentition.
Israel journal of dental sciences, 1988
Israel journal of dental sciences, 1988
ASDC journal of dentistry for children
The effect of premature extractions of primary molars on further development of their successors ... more The effect of premature extractions of primary molars on further development of their successors was studied. A group of forty-six children with fifty-three unilaterally extracted mandibular primary molars was examined when the successors completed their root development. Radiographs of the successors to the extracted molars and their antimeres, which served as internal controls, were taken using the long-cone technique. Crown and root length and area in cross-section, were measured from tracings of the studied teeth and crown/root ratios were calculated. Significantly (p less than 0.05) larger area ratio in the extraction group was found suggesting a smaller root area. In addition, root foreshortening for the first premolars and diminished root area for the second premolars, both successors to teeth extracted after the age of eight years, were found. Although statistically significant, all of the differences were of no clinical importance.
British journal of orthodontics, Aug 1, 1997
The prevalence of occlusal features in 939 children, aged 6-13 years, belonging to an ultra-ortho... more The prevalence of occlusal features in 939 children, aged 6-13 years, belonging to an ultra-orthodox community of Jewish Ashkenazi descent living in Jerusalem was studied clinically. Sexual dimorphism was found for overjet, overbite, and habit practising. About one-quarter of the sample exhibited some degree of occlusal mutilation due to caries, thus creating a 'caries-affected' subgroup, the rest forming the 'caries-free' subgroup. In the latter set, normocclusion was scarce (7.4 per cent), Class I being the most frequent malocclusion (49.1 per cent). Caries had a significant effect on the symmetry of bilateral occlusal relationships, lower dental midline deviation, and on crowding/spacing conditions in the mixed dentition stage (except for the maxilla in late mixed dentition). The low prevalence of normocclusion can be attributed to genetic background, environmental influences and the definition attached to normal occlusion.
PubMed, Sep 1, 1991
The effect of premature extractions of primary molars on further development of their successors ... more The effect of premature extractions of primary molars on further development of their successors was studied. A group of forty-six children with fifty-three unilaterally extracted mandibular primary molars was examined when the successors completed their root development. Radiographs of the successors to the extracted molars and their antimeres, which served as internal controls, were taken using the long-cone technique. Crown and root length and area in cross-section, were measured from tracings of the studied teeth and crown/root ratios were calculated. Significantly (p less than 0.05) larger area ratio in the extraction group was found suggesting a smaller root area. In addition, root foreshortening for the first premolars and diminished root area for the second premolars, both successors to teeth extracted after the age of eight years, were found. Although statistically significant, all of the differences were of no clinical importance.
PubMed, 1989
Lower face height indicators and mandibular rotation are assessed at 7 and 12 years of age in a s... more Lower face height indicators and mandibular rotation are assessed at 7 and 12 years of age in a sample of 46 children, comparing the corpus axis and mandibular plane as indicators of change in mandibular position. The parameters involving the mandibular plane consistently show higher correlations.
American Journal of Orthodontics, Feb 1, 1981
Previous experiments indicate that bone cells respond to externally applied stimuli with jhtctuat... more Previous experiments indicate that bone cells respond to externally applied stimuli with jhtctuations of cyclic nucleotide levels. The objective of this experiment was to study the response of bone at the midpalatal suture to the application of tensile forces in young and old animals, through an examination of the osteoblastic staining pattern jor CAMP and cGMP. The midpalatal suture was rapidly expanded for 0, 10, and 15 days, respectively, in three young and three old cats. Fresh, ,frozen, unhxed, undecalcij5ed maxillae were sectioned transversely and stained immunohistochemically for CAMP and cGMP. The staining intensity for both nucleotides was increased in the osteoblasts of the young treated animals, while in the old animals the osteoblasts were only faintly stained for CAMP and cGMP. These results demonstrate that bone cells of old animals are less responsive to tensile jorces than the corresponding cells in young animals.
Dental Traumatology, Jun 1, 2000
Increased overjet and inadequate lip coverage of the maxillary incisors are considered significan... more Increased overjet and inadequate lip coverage of the maxillary incisors are considered significant risk factors in many clinical studies. The purpose of the present study was to examine this issue of dental injury by actual cephalometric measurements in orthodontic patients. Pretreatment cephalograms (taken with lips in repose) of consecutive patients were used. The patients were allotted to two groups Group T (trauma): 56 patients who had injured their maxillary incisors prior to their orthodontic treatment, mean age at the start of treatment 11.9 years (SD = 1.5); and Group C (control): 98 patients with intact maxillary incisors, mean age at the start of treatment 11.6 years (SD = 1.3). Twelve cephalometric landmarks on the soft and hard tissue profile were identified and digitized and the relevant dental, skeletal and soft tissue measurements recorded. The variables in Groups T and C were compared and their predictive values for possible occurrence of trauma were tested by logistic regression analysis. No statistically significant differences between boys and girls were found. Overjet or maxillary incisor exposure or interlabial gap, each as a single variable, could differentiate between the two groups. Logistic regression analysis indicated that only a small percentage (28.7%) of the dependent variable variation (trauma vs control) can be explained by interlabial gap, gender, upper incisor long axis to facial plane (degree), upper incisor long axis to interlabial gap and overjet.
American Journal of Orthodontics, May 1, 1982
American Journal of Orthodontics and Dentofacial Orthopedics, Nov 1, 1992
Knowledge of the normal dentofacial patterns of various ethnic groups is important for clinical a... more Knowledge of the normal dentofacial patterns of various ethnic groups is important for clinical and research purposes. The objective of this study was to describe the dentofacial pattern of one Jewish ethnic group and to compare it with accepted standards for other white populations. Lateral cephalometric radiographs of 18 children of Jewish East European origin with clinically acceptable permanent occlusion, ages 11 to 13 years, were used. A computer-aided cephalometric analysis was performed, and the mean values and standard deviations for the various cephalometric variables were obtained. When compared with some classical standards, it was found that this ethnic group tended toward a mild skeletal Class II, a convex profile, and a more vertical direction of growth. These features appeared in persons selected on the basis of a clinically acceptable occlusion, suggesting the existence of dental compensations. Understanding these natural accommodations of the dentition to skeletal variations can be clinically useful when establishing treatment goals. (AM J ORTHOD DENTOFAC ORTHOP 1992;102:443-8.) Cephalometric characteristics of various races and ethnic groups have been presented by several researchers t7 as this knowledge is important for clinical and research purposes. The present study is a survey of the skeletal and dental patterns of Jewish adolescents of East European origin who have normal occlusion, cephalometric analysis being the method used. The dispersal of the Jews from Ancient Palestine resulted in the foundation of Jewish communities throughout the world. At the end of the 18th century, the Jews began to return to Israel in waves, which reached a climax after the establishment of the state in 1948. In the Middle Ages, the Jews from Central and Eastern Europe were referred to as Ashkenazi Jews. They comprise one of the largest Jewish ethnic groups. Our objective is to describe the characteristic cephalometric dentofacial pattern of a sample of this ethnic group, and in addition, to document the differences between this sample and some American white samples. MATERIALS AND METHODS The data base for this report originates from the material collected in 1969 to 1971 for a growth study of seven ethnic
The Cleft Palate-Craniofacial Journal, Mar 1, 1992
International Journal of Anthropology, 1996
Archives of Oral Biology, Oct 1, 2001
The periodontal vasculature encircling the entire length of the rat lower incisor was studied at ... more The periodontal vasculature encircling the entire length of the rat lower incisor was studied at the time of tipping movement and 3 months later. In 12 rats (212+/-4 g b.w.), loads (0.19+/-0.016 N) were applied to the lower left incisor in a linguointrusive direction. After 2 weeks of loading, six experimental animals were killed with the loading springs in place. The springs were removed in the six remaining rats, which were killed 12 weeks later. Six additional rats with intact teeth served as control. All incisors were fixed, demineralized, embedded in glycol methacrylate and cross-sectioned perpendicular to the long axis of the tooth. The distance of each section (2 microm) from the apex was calculated. A computerized image-analysis program was used to measure the width and area of the labial and lingual periodontal ligament to establish whether the measured segments corresponded to the compressed or expanded zones. In each cross-section, the various types of blood vessels were counted and the cross-sectional area of all venous vessels was measured. The results showed that after 2 weeks of loading (1) the general trend of vascular changes was similar under pressure and tension; (2) the large-diameter vessels were unaffected by loading; (3) the mean number of terminal arterioles had decreased significantly, while the number of capillaries and postcapillary venules had increased significantly in the apical tooth part; (4) the venous blood vessel area had decreased significantly in the apical tooth part; (5) the intensity of the vascular reaction was dependent on the degree of tissue distortion; and (6) after 12 weeks' recovery the vascular changes were still present, demonstrating a rebound effect. The findings suggest that microvascular alterations following tooth loading are not directly related to the spatial effect of loading itself and are of a much longer duration than expected.
Journal of Dental Education, Dec 1, 1990
International Journal of Osteoarchaeology
Malocclusion is a well‐known phenomenon since antiquity. Previous studies found an increase in ma... more Malocclusion is a well‐known phenomenon since antiquity. Previous studies found an increase in malocclusion in the modern population. This study was undertaken to assess the frequency and severity of malocclusions in a sample of ancient skulls and to compare these findings with a modern sample, using the same examination protocol. The archaeological sample comprised 63 skulls from Dor, northern Israel, dated to the 16th–19th centuries. Skull examination was performed in maximal occlusion by using a clinically based approach. The modern sample comprised a random, ethnicity‐matched group of 340 school students, aged 11–16 years, who underwent a clinical orthodontic examination. The following parameters were recorded for both groups: Angle's classification, overjet, overbite, crowding, spacing, midlines, and crossbite. Descriptive statistics was obtained for all the parameters examined, and the results were compared between the groups. Differences were considered significant at p &...
Journal of clinical orthodontics, Sep 1, 1984
Journal of clinical orthodontics : JCO, 1985
Pediatric dentistry, 1985
This clinical and radiographic investigation was undertaken in an attempt to correlate the develo... more This clinical and radiographic investigation was undertaken in an attempt to correlate the developmental stage of the permanent tooth buds, the chronological age at the time of trauma, and the degree of primary root resorption with mineralization defects in the permanent Successors. One hundred children who had experienced trauma to their primary incisors were recalled and their immediate posttrauma radiographs were examined. Sixty-four exhibited possible signs of previously unnoticed and unreported trauma and were eliminated from the study. This high percentage of unnoticed injury indicates the need for careful radiographic examination to discover signs of previous trauma when attempting to correlate developmental disturbances with injury to primary incisors. Discoloration of the crown of the permanent tooth was evident in 16% of the children with the incisal one-third being the most common site. Hypoplasia was evident in 9% of the permanent teeth. No association could be established between the amount of primary root resorption and the appearance of mineralization defects on the permanent successors. Correlation between trauma to the primary teeth and the presence of mineralization defects in the permanent dentition has been described previously.
Pediatric dentistry, 1984
One hundred and twenty-four children who had experienced trauma to their primary incisors were in... more One hundred and twenty-four children who had experienced trauma to their primary incisors were included in this clinical investigation in an attempt to correlate the type of injury occurring to the primary teeth, the age of the patient at the time of trauma with mineralization defects, and intra- and interarch relationships of the permanent incisors. Thirty-four per cent of the
Pediatric dentistry, 1986
Trauma to the primary incisors may, by their displacement, cause developmental disturbances in th... more Trauma to the primary incisors may, by their displacement, cause developmental disturbances in the root formation of the permanent incisors. To verify this hypothesis, dental radiographs of 34 children, whose primary incisors had been previously injured, were evaluated. Only 6 children showed disturbances in root development of maxillary permanent incisors. Three cases in which trauma to the primary dentition resulted in pathology to the permanent dentition are presented, stressing the need for close periodic examination and early detection of possible developmental defects in the permanent dentition.
Israel journal of dental sciences, 1988
Israel journal of dental sciences, 1988
ASDC journal of dentistry for children
The effect of premature extractions of primary molars on further development of their successors ... more The effect of premature extractions of primary molars on further development of their successors was studied. A group of forty-six children with fifty-three unilaterally extracted mandibular primary molars was examined when the successors completed their root development. Radiographs of the successors to the extracted molars and their antimeres, which served as internal controls, were taken using the long-cone technique. Crown and root length and area in cross-section, were measured from tracings of the studied teeth and crown/root ratios were calculated. Significantly (p less than 0.05) larger area ratio in the extraction group was found suggesting a smaller root area. In addition, root foreshortening for the first premolars and diminished root area for the second premolars, both successors to teeth extracted after the age of eight years, were found. Although statistically significant, all of the differences were of no clinical importance.