Shafia Allaqaband | Hamdard University (original) (raw)

Papers by Shafia Allaqaband

International Journal of Advanced Research, 2017

Asian Journal of Pharmaceutical and Clinical Research, 2022

Objective: The objective of the study was to evaluate the laboratory parameters of polyherbal Una... more Objective: The objective of the study was to evaluate the laboratory parameters of polyherbal Unani formulation with simple shampoo base used in seborrheic dermatitis (Huzaz) of scalp. Methods: Evaluation of test drug formulation with shampoo base was done for its appearance, pH, % of solid contents, wetting time, density, viscosity, dirt dispersion test, froth test, and skin irritation test. Results: Polyherbal formulation along with simple shampoo base was dark brown in color, thin in consistency, and with pungent aroma. pH of poly herbal formulation was 8.27 which will have positive effect on greasy and thin hairs. Solid contents were moderately easy to wash. Wetting time was 200 s, density was 1.17 g, and viscosity was 2.33 moderately good. Froth test showed froth >8 cm. Skin sensitivity on albino rats showed no allergic reaction. Conclusion: Polyherbal Unani formulation can be a promising drug with least side-effects and cost-effective in treating dandruff which relapses eve...

International Journal of Advanced Research, 2022

Psoriasis is a chronic disorder with impact on quality of life and its high rate of relapse is no... more Psoriasis is a chronic disorder with impact on quality of life and its high rate of relapse is noted every now and then. The disease of psoriasis has been prevalent in mankind since time immorial and the disease runs a chronic course. Da-us-sadaf (psoriasis) is an Arabic word da meaning disease and as sadaf meaning molluscum shell. Psoriasis is marked by shell like silvery white scales or flakes which keep on shedding from the horny layer of skin. Many eitioathological conditions predispose to psoriasis which includes genetic, environmental and immunological factors. According to Unani system of medicine, preponderance of melancholic humours present in human body is believed to be the cause. The prevalence of psoriasis in India varies from 0.44 to 2.8%. Hijamah (cupping) is one of the oldest method of treatment of Unani system of medicine in with cups are used to produce suction and bloodletting is done from the affected area. During our study cups were applied at interscapular area...

According to Unani system of medicine, health is attributed to the quantitative and qualitative e... more According to Unani system of medicine, health is attributed to the quantitative and qualitative equilibrium of Akhlat (humours) i.e Damvi (sanguinous), Safra (bilious), Balgham (Phelgamatic) and Saudah (melancholic). Besides this, there is Asbab e Sittah Zarooriya (six essential factors) which are the main determinants of health.These include atmosphereric air (hawa), food and drinks (makool mashroobat), bodily movements and repose (Harkat-wa-Sakoon Badni), mental activity and repose (Harkatwa- Sakoon Nafsani), sleep and wakefulness (Naum Wa Yaqza) and retention and excretion (Ahtibas wa Istifiragh).These factors are highly modifiable and any imbalance in any of these factors is likely to cause diseases. Proper evacuation of morbid materials is the prerequisite of humoral equilibrium or in other words maintenance and restoration of health. The elimination of morbid materials can effectively be achieved by the process of Nuzj (concoction) and Is’haal (purgation) which is one of the b...

There are no adequate data that evaluate the safety and effectiveness of lowering triglyceride le... more There are no adequate data that evaluate the safety and effectiveness of lowering triglyceride levels in infants. The authors report a neonate affected by Familial hyperchylomicronemia syndrome, while being investigated for sepsis the serum sample obtained for blood counts was discovered to be lipaemic and the case was subsequently investigated for dyslipidemia. Based on this very abnormal lipid profile compared to her age, we started her on statins. The parents were referred to a dietitian vigorous dietary fat restriction supplemented by fat-soluble vitamins including mixing food with olive oil and giving skimmed dairy products as she is growing. Follow up is ongoing.

International Archives of BioMedical and Clinical Research, 2017

Turmus (Lupinus albus) is an annual and perennial herbs, confined mostly to North and South Ameri... more Turmus (Lupinus albus) is an annual and perennial herbs, confined mostly to North and South America, Africa and Europe. It is sown in Italy, Sicily. It was indigenous to Mediterranean region from where it spread to other countries. None of them recorded wild in India. An herbaceous erect annual plant 45-120cm. leaves are digitate. Leaflets are obviate-oblong. Flowers are white. Pods are large, stout beaked hairy. Seeds are orbicular, compressed and white in colour, bitter in taste and yellowish orange in color internally. It has two varieties wild and garden lupinus with little difference. Its Chemical constituents include Lupinine, Luplinin, Lupanine and hydroxylupanine, carbohydrates, asparagines, Protein, Fat, Sugar, Minerals K, Ca, Mg, Na, P and Fe etc. Based on its rich chemical constituents it has many pharmacological actions such as anti inflammatory, cleansing, diuretic, ammenogoggue, Abortificient, antihelminthic, analgesic etc. It has many therapeutic uses such as in hemorrhoids, Ascitis, pruritis, anorexia, sciatica, herpes, ulcers, acne etc. recently it has been seen to be effective in diabetes and hypertension. It has been important as a hair tonic, it is used against dandruff and is used for straightening of hairs. Key words; Abortificient, antihelminthic, analgesic, Lupinous

There is no direct concept of Alopecia areata in Unani medicine. However there is a comprehensive... more There is no direct concept of Alopecia areata in Unani medicine. However there is a comprehensive description of Daus Saalab, Daul Hyya and Safa in classical Unani literature. The clinical features of these disease entities resembles with alopecia described in contemporary medicine. Alopecia areata means loss of hairs in areas where ordinarily hair would be found. It is actually a type of non scaring alopecia that affects males and females equally and occurs in both children and adults .The peak age of occurrence is 20 to 50 years .The most common clinical presentation is asymptomatic shedding of telogen hairs followed by patchy non scarring hair loss in association with nail pitting, Beau’s line and nail dystrophy. The disease may progress from this limited presentation to loss of all scalp hair (Alopecia totalis) or all body hair (alopecia universalis) with significant onychodystrophy. It may also affect eye brows, eye lashes and beard. According to Ibn e Sina, a legendary Unani physician, the disease can occur in any part of body but scalp, face and eyebrows are the commonest sites. Its various causes are elucidated as accumulation of Ratoobate Fasida, Saudae khabes, Fasade Dam, Balgami shoor,Safra Lazae, Ajsaame Khabeesa, Zoafe Asaab, excessive coitus, unhygienic conditions etc. Despite the effective therapeutic regimes currently available for Alopecia in western medicine, there remain many patients who fail to respond adequately or develop side effects. Unani system of medicine offers a very effective treatment for this disease based on its holistic approach. Key words: Alopecia areata, Daus Saalab, Daul Hyya, Safa and Unani medicine

In Unani system of medicine there are four modes of treatment these are; Illaj bil ghiza (dietoth... more In Unani system of medicine there are four modes of treatment these are; Illaj bil ghiza (dietotherapy), Illaj bil Dawa (pharmacotherapy), Illaj bit tadbeer (Regimenal therapy) and Illaj bil yad (surgery). Illaj bit Tadbeer includes a number of regimenal interventions such as Hijamah (cupping), Irsal alaq (leeching), Fasd (venesection), Dalak (massage), Nutool (irrigation), Qay (Emesis), Idrar-i-Bawl (Diuresis), Tariq (Diaphoresis), Munzij and Mu'shil therapy (Concoction and purgation), Bukhoor (medicated steam), kayy (cauterization), Huqna (enema) etc. Among these regimens Nutool is a novel method in which water, oil or medicated decoction is poured from a height over specific sites of body in certain diseases. This process is called Tanteel (irrigation). Depending upon the nature of liquids used for desired actions in this therapy it has been broadly divided into two types; Nutool Haar and Nutool Barid. Nutool or irrigation is done with a purpose of acceleration of process of ...

Bafa (dandruff) is a common scalp disorder affecting almost half of the population at the pre-pub... more Bafa (dandruff) is a common scalp disorder affecting almost half of the population at the pre-pubertal age of either gender or ethnicity. No population in any geographical region would have passed through freely without being affected by dandruff at some stage in their life. Dandruff (pityriasis capitis, seborrheic dermatitis confined to scalp) is a disease that has been around for centuries despite several treatment options. Although the exact cause of SD has yet to be known, Malassezia yeasts, hormones (androgens), sebum levels and immune response are known to play important roles in its etiopathogenesis. Since centuries, Unani medicine has been used in the treatment of Bafa. Keeping in mind the desirable action, the quantitative analysis for saponins of a polyherbal formulation used in Bafa was done. Saponins are high-molecularweight glycosides, consisting of a sugar unit(s) linked to a triterpene or a steroid aglycone. Many saponins have detergent properties. Saponins lower the ...

According to Unani system of medicine, health is attributed to the equilibrium of akhlat (humors)... more According to Unani system of medicine, health is attributed to the equilibrium of akhlat (humors), besides this there is asbab-e-sittah zarooriya (six essential factors). These are air, food and drinks, bodily movements and repose (harkat-wa-sakoon badni), mental activity and repose (harkat-wa-sakoon nafsani), sleep and wakefulness (naum wa yaqza) and retention and excretion (ahtibas wa istifiragh). Any imbalance in any of the above factors is likely to cause disease. Normal sleep is thought to be because of ratoobat wa baroodat i.e. wetness and cold in our body and if there is derailment of balance in sleep and wakefulness, it implies the predominance of yuboosat wa hararat i.e. dryness and hotness widespread in the brain. Insomniacs complain of difficulty falling asleep, difficulty staying asleep, poor quality sleep, or inadequate sleep despite adequate opportunity. In addition, the sleep disturbance causes clinically significant distress or impairment in social, occupational, edu...

Journal of Pharmaceutical & Scientific Innovation, 2014

Journal of Drug Delivery and Therapeutics

Objective: to report cases of Telogen effluvium (T.E) as a sequele of COVID 19 Material and metho... more Objective: to report cases of Telogen effluvium (T.E) as a sequele of COVID 19 Material and methods: Ten patients were reported between May and august 2021with median age group of 21years. There were five males and five females in the study. All the cases were diagnosed with positive RTPCR when they had COVID and recovered fully without need for hospitalization. T.E occurred in our group after median of two months (range 1-2months) following COVID 19 infection. Detailed medical history of all the patients was taken. Results: all the ten cases showed early onset of T.E within three months of infection. Keywords: Telogen Effluvium, Covid 19, RTPCR

Introduction: Skin disease are been successfully treated with Unani system of medicine for thousa... more Introduction: Skin disease are been successfully treated with Unani system of medicine for thousands of years. Here we report three cases of various skin diseases commonly prevalent in Kashmir i.e. frost bite, contact irritant dermatitis and ringworm infection. Methodology: here we report three cases of frost bite, contact irritant dermatitis and ringworm infection respectively that were given same Unani treatment both orally and locally respectively. Results were based on liker scale for sign and symptoms. Photographs were taken before and after treatment. Results: All the three patients were treated by same mode of treatment successfully revalidating its efficacy and have promising results which could further be evaluated in large clinical trials.

International Journal of Scientific Reports, 2017

Contact dermatitis is an allergic reaction of skin which occurs in response to a substance that c... more Contact dermatitis is an allergic reaction of skin which occurs in response to a substance that comes in contact with surface of skin. Irritant contact dermatitis is one of the type of contact dermatitis, most frequently caused by occupational exposure either as an industrial contact or household contact. In Unani medicine, contact dermatitis has been described as an eruption on skin surface in which initially there is erythema, burning sensation followed by formation of papules along with itching on the affected site. Here we report a case study of 54 years male, working in sewage treatment plant having being diagnosed of Irritant contact dermatitis on palmer surfaces of both hands. Patient was given Unani treatment both oral as well as local and was asked for follow up every week. After 28 days of treatment patient had significant improvement with mild scales and no erythema .

Background: we report a case 16 years old young female who suffered from frostbite on dorsum of b... more Background: we report a case 16 years old young female who suffered from frostbite on dorsum of both feet. Case presentation: socio-demographic background, cause, resulting lesion and subsequent management by Unani system of medicine are discussed. Conclusion: such cases are frequently found in high altitude areas and can be managed well by Unani system of medicine.

Alopecia areata (AA) is a disease marked by extreme variability in hair loss, not only at the tim... more Alopecia areata (AA) is a disease marked by extreme variability in hair loss, not only at the time of initial onset of hair loss but in the duration, extent and pattern of hair loss during any given episode. This variable and unpredictable nature of spontaneous re-growth and lack of a uniform response to various therapies has made clinical trials in alopecia areata difficult to plan and implement. It is a type of alopecia that affects males and females equally. It occurs in both children and adults. The peak age of occurrence is 20 to 50 years .The most common clinical presentation is asymptomatic shedding of telogen hairs followed by patchy non scarring hair loss in association with nail pitting, Beau's line and nail dystrophy. The disease may progress from this limited presentation to total loss of all scalp hairs (Alopecia totalis) or all body hair (alopecia universalis) with significant onychodystrophy. Mostly it is characterised by reversible hair loss involving the scalp although others areas of head including eyelashes, eyebrows and beard may also be affected. Although, it is a mostly cosmetic problem but it often has devastating effects on quality of life and self-esteem. The paper aims at providing an overview of Alopecia areata.

Background: Gilbert’s Syndrome (GS) is the most common form of congenital, non haemolytic, mild U... more Background: Gilbert’s Syndrome (GS) is the most common form of congenital, non haemolytic, mild Unconjugated Hyperbilirubinaemia. Familial cases linked with mutation in enzyme UDP glucoronosyl transferase 1producing decreased conjugation of bilirubin which accumulates in the form of unconjugated bilirubin. Hyperbilirubinaemia is mild (<6 mg/dl) while liver enzymes & histology are always found normal. It is clinically characterized by vague symptoms like loss of appetite, abdominal pain, weight loss and mild Jaundice. A review of Unani literature showed disease similarity clinically with Su-e-Mizaj Jigar Har Yabis, with dominating features of Safra (yellow bile). Material & Methods: We report our experience with such a case of GS by validated integrative assessment and management with Unani Medicine e.g Arqayat (Makoh+Kasni+Biranjasif), Jigreen, Sharbat-e-Bazoori and Majoon Dabid-ul-Ward along with a short review of literature. Results were analyzed based on clinical and LFT outcomes. Results: Significant symptomatic relief was achieved over 5 weeks of treatment. Bilirubin levels normalized but rose after 5 weeks. Literature review showed disease similarity with Su-e-Mizaj Har Yabis Sadaa which under the aggravating factors progressed to Su-e-Mizaj Har Safrawi. Conclusion: As single abnormal gene in the GS runs in the families & leads to reduced enzymatic expression. This decreases conjugation of unconjugated bilirubin and ultimately unconjugated hyperbilirubinaemia. There by normal levels of bilirubin were achieved for concise period of time with symptomatic relief which proves the effectiveness of Unani medicine in GS but establishment of the therapy needs planned study on multiple patients.