ICD-10-CM Diagnosis Code C48.1 - Malignant neoplasm of specified parts of peritoneum (original) (raw)

ICD List 2025-2026 Edition

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2. ICD-10-CM Codes
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5. C48
6. 2026 ICD-10-CM Code C48.1

Malignant neoplasm of specified parts of peritoneum

ICD-10-CM Code:

C48.1

ICD-10 Code for:

Malignant neoplasm of specified parts of peritoneum

Is Billable?

Yes - Valid for Submission

Chronic Condition Indicator: [1]

Chronic

Code Navigator:

C48.1 is a billable diagnosis code used to specify a medical diagnosis of malignant neoplasm of specified parts of peritoneum. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic cul-de-sac (Douglas') ; Neoplasm, neoplastic Douglas' cul-de-sac or pouch ; Neoplasm, neoplastic mesentery, mesenteric ; Neoplasm, neoplastic mesoappendix ; Neoplasm, neoplastic mesocolon ; Neoplasm, neoplastic omentum ; Neoplasm, neoplastic peritoneum, peritoneal (cavity) parietal ; etc

1. Code Information
2. Approximate Synonyms
3. Clinical Classification
4. Clinical Information
5. Tabular List of Diseases and Injuries
6. Diagnostic Related Groups Mapping
7. Convert to ICD-9 Code
8. Table of Neoplasms
9. Patient Education
10. Other Codes Used Similar Conditions
11. Code History

• Neoplasms
  C00–D49
  • Malignant neoplasms of mesothelial and soft tissue
    C45-C49
    * Malignant neoplasm of retroperitoneum and peritoneum
    C48

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

• Malignant neoplasm of mesentery
• Malignant neoplasm of mesocecum
• Malignant neoplasm of mesocolon
• Malignant neoplasm of mesorectum
• Malignant neoplasm of omentum
• Malignant neoplasm of pelvic peritoneum
• Malignant neoplasm of the pouch of Douglas
• Neoplasm of omentum
• Neoplasm of omentum
• Neoplasm of omentum
• Neoplasm of omentum
• Neoplasm of rectouterine pouch
• Neoplasm of rectouterine pouch
• Neoplasm of the mesocolon
• Neoplasm of the mesocolon
• Primary malignant neoplasm of omentum
• Primary malignant neoplasm of parietal peritoneum
• Primary malignant neoplasm of pelvic peritoneum
• Primary malignant neoplasm of rectouterine pouch
• Primary malignant neoplasm of the mesentery
• Primary malignant neoplasm of the mesocolon
• Primary myosarcoma of omentum
• Primary sarcoma of peritoneum
• Primary sarcoma of soft tissues of abdomen
• Sarcoma of mesentery
• Sarcoma of omentum
• Sarcoma of pelvic peritoneum
• Sarcoma of peritoneum
• Sarcoma of peritoneum
• Sarcoma of peritoneum
• Sarcoma of peritoneum

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

CCSR Code: NEO020

Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

• Mesocolon

the fold of peritoneum by which the colon is attached to the posterior abdominal wall.

• Omentum

a double-layered fold of peritoneum that attaches the stomach to other organs in the abdominal cavity.

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

ICD-9-CM: 158.8

Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Filter table of neoplasms:

Cancer

What is cancer?

Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor.

Tumors can be benign or malignant. Benign tumors aren't cancer, while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of your body. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the type of cancer and how advanced it is.

What are the types of cancer?

There are more than 100 different types of cancer. Cancer can start almost anywhere in your body. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast.

Cancer may also be described by the type of cell that formed it, such as sarcoma if cancer begins in your bone and soft tissue. Carcinoma is the most common type of cancer. It is formed by epithelial cells, the cells that cover the inside and outside surfaces of your body.

How does cancer develop?

Cancer is a genetic disease. That means changes in your genes cause it. Changes in your genes are also called gene variants or mutations. Genes are parts of DNA in your cells that you inherit from your parents. However, only some cancers are caused by genes passed down from your parents.

Genetic changes can occur to your genes over your lifetime that affect how your cells function. Usually, your body gets rid of damaged cells before they turn cancerous, but this ability goes down as you age. Other factors that may affect your risk of developing cancer can include:

• Exposure to ultraviolet (UV) rays from the sun
• Smoking
• Your diet
• Physical inactivity

What are the symptoms of cancer?

Cancer symptoms depend on the type of cancer. For example, some of the symptoms that cancer may cause can include:

• A lump in your breast
• Blood in your urine (pee) or stool (poop)
• Bleeding or bruising for no known reason
• A sore that doesn't heal
• Trouble swallowing
• A new mole or a change to a mole you already have

Cancer may cause various symptoms but often doesn't cause pain. Don't wait until you're having pain before seeing your health care provider. See your provider if you have symptoms that don't get better in a few weeks.

How is cancer diagnosed?

There is no single test that can diagnose cancer. The tests ordered are usually based on your symptoms. Your provider may:

• Ask about your medical history
• Ask about your family health history, including relatives who have had cancer
• Do a physical exam
• Do a screening test such as a mammogram, colonoscopy, or a Pap test
• Order blood tests or imaging tests

To find out if you have cancer, your provider may order a biopsy. A biopsy is the procedure of removing and examining tissue, cells, or fluids from your body.

What are the treatments for cancer?

Treatment depends on the type of cancer and how advanced it is. Most treatment plans may include surgery, radiation, and/or chemotherapy. Some may involve hormone therapy, immunotherapy or other types of biological therapy, or stem cell transplantation.

Can cancer be prevented?

It's usually not possible to know exactly why cancer develops in some people but not others. There are some things that you can't control which may increase or decrease your risk of getting cancer, such as inheriting certain genes or your age. But some lifestyle habits may increase your risk of certain types of cancer. Avoid or reduce lifestyle habits such as:

• Smoking and tobacco use
• Having too much sun exposure
• Drinking too much alcohol
• Not getting enough physical activity
• Having obesity

NIH: National Cancer Institute

[Learn More in MedlinePlus]

Peritoneal Disorders

Your peritoneum is the tissue that lines your abdominal wall and covers most of the organs in your abdomen. A liquid, peritoneal fluid, lubricates the surface of this tissue.

Disorders of the peritoneum are not common. They include:

• Peritonitis - an inflammation of the peritoneum
• Cancer
• Complications from peritoneal dialysis

Your doctor may use imaging tests or lab tests to analyze the peritoneal fluid to diagnose the problem. Treatment of peritoneal disorders depends on the cause.

[Learn More in MedlinePlus]

Ovarian Epithelial, Fallopian Tube, and Primary Peritoneal Cancer Treatment (PDQ®)

Learn about ovarian epithelial, fallopian tube, and primary peritoneal cancer risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.
[Learn More in MedlinePlus]

Soft Tissue Sarcoma-Patient Version

Learn about soft tissue sarcoma risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.
[Learn More in MedlinePlus]

• FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026

• FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024

• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023

• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022

• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019

• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018

• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017

• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

• Previous Code: C48.0

• Parent Code: C48

• Next Code: C48.2