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Research paper thumbnail of Cardiac resynchronization therapy

University Heart Journal, 2009

In this issue of the Journal, Giraldi et al. (1) compare transvenous and epicardial lead placemen... more In this issue of the Journal, Giraldi et al. (1) compare transvenous and epicardial lead placement in patients with unfavorable coronary sinus anatomy. Patients who met standard criteria for cardiac resynchronization therapy (CRT) including left ventricular (LV) dysfunction, New York Heart Association class III to IV congestive heart failure, and left bundle branch block, who were on optimal medical therapy underwent pre-operative multislice computed tomography to evaluate coronary sinus (CS) anatomy. Patients with CS veins that were absent, tortuous, angled acutely, or very small were prospectively randomized to LV lead implantation by epicardial minimally invasive thoracotomy versus conventional endocardial lead placement.

Research paper thumbnail of Effects of hyperuricemia on perinatal outcome in hypertensive disorder of pregnancy

University Heart Journal, 2008

The purpose of this study was to detect elevated uric acid level in maternal blood, presumably du... more The purpose of this study was to detect elevated uric acid level in maternal blood, presumably due to decrease renal urate excretion, for early detection of hypertensive disorder in pregnancy. This study showed that serum uric acid was significantly elevated in all cases of preeclampsia. The present study showed that serum uric acid levels were significantly elevated in eclampsia as compared with the levels in pregnancies complicated by hypertension (p<0.05). The level of uric acid above 4.5 mg/dl is indicative of preeclamptic process and in such cases; the subjects deserve careful and close clinical follow up. Increasing higher concentration of uric acid i.e. 5.7 mg/dl, 6.3mg/dl, and 6.72mg/dl was observed in pregnancy with chronic hypertension, preeclampsia and eclampsia respectively. These results showed that serum uric acid could be used as a sensitive indicator of severity of preeclampsia. Out of 100 cases, there were 20 preterm baby and others such as stillbirth and IUD. So, these entire abnormal fetal outcomes were in the hyperuricaemic group and 5.37 times higher as compared to low serum uric acid group. Mean birth weight of preeclampsia and eclampsia were 2.31kg and 2.30kg respectively compared with 2.5kg in chronic hypertension group.

Research paper thumbnail of Units converter

Research paper thumbnail of Cardiac resynchronization therapy

University Heart Journal, 2009

In this issue of the Journal, Giraldi et al. (1) compare transvenous and epicardial lead placemen... more In this issue of the Journal, Giraldi et al. (1) compare transvenous and epicardial lead placement in patients with unfavorable coronary sinus anatomy. Patients who met standard criteria for cardiac resynchronization therapy (CRT) including left ventricular (LV) dysfunction, New York Heart Association class III to IV congestive heart failure, and left bundle branch block, who were on optimal medical therapy underwent pre-operative multislice computed tomography to evaluate coronary sinus (CS) anatomy. Patients with CS veins that were absent, tortuous, angled acutely, or very small were prospectively randomized to LV lead implantation by epicardial minimally invasive thoracotomy versus conventional endocardial lead placement.

Research paper thumbnail of Effects of hyperuricemia on perinatal outcome in hypertensive disorder of pregnancy

University Heart Journal, 2008

The purpose of this study was to detect elevated uric acid level in maternal blood, presumably du... more The purpose of this study was to detect elevated uric acid level in maternal blood, presumably due to decrease renal urate excretion, for early detection of hypertensive disorder in pregnancy. This study showed that serum uric acid was significantly elevated in all cases of preeclampsia. The present study showed that serum uric acid levels were significantly elevated in eclampsia as compared with the levels in pregnancies complicated by hypertension (p<0.05). The level of uric acid above 4.5 mg/dl is indicative of preeclamptic process and in such cases; the subjects deserve careful and close clinical follow up. Increasing higher concentration of uric acid i.e. 5.7 mg/dl, 6.3mg/dl, and 6.72mg/dl was observed in pregnancy with chronic hypertension, preeclampsia and eclampsia respectively. These results showed that serum uric acid could be used as a sensitive indicator of severity of preeclampsia. Out of 100 cases, there were 20 preterm baby and others such as stillbirth and IUD. So, these entire abnormal fetal outcomes were in the hyperuricaemic group and 5.37 times higher as compared to low serum uric acid group. Mean birth weight of preeclampsia and eclampsia were 2.31kg and 2.30kg respectively compared with 2.5kg in chronic hypertension group.

Research paper thumbnail of Units converter

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