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Papers by Ahmet Aslan

Case Reports in Gastroenterology, 2008

Hepatic tuberculosis is a rare manifestation of extra-pulmonary tuberculosis. Hepatic tuberculous... more Hepatic tuberculosis is a rare manifestation of extra-pulmonary tuberculosis. Hepatic tuberculous lesions are especially mimicking tumour-like mass or cystic lesions in the liver and so can be misdiagnosed with several diseases. Histopathological examination of the specimen is essential in the diagnosis for hepatic tuberculosis. In this report, two cases with hepatic tuberculosis having cystic solid mass and abscess liver lesions are described.

Advances in Therapy, 2008

Introduction Propolis is the generic name for the resinous substance collected by honeybees, whic... more Introduction Propolis is the generic name for the resinous substance collected by honeybees, which is known to have antioxidant, anti-inflammatory, apoptosis-inducible effects. Anastomotic dehiscence after colorectal surgery is an important cause of morbidity and mortality. We aimed to assess the effect of propolis on healing in an experimental colon anastomosis in rats. Methods Forty adult male Wistar albino rats were randomly assigned into 5 treatment groups with 8 rats in each: Group I, anastomosis+no treatment; Group II, anastomosis+oral propolis (600 mg/kg/d); Group III, anastomosis+oral ethyl alcohol (1 cc/d); Group IV, anastomosis+rectal propolis (600 mg/kg/d); Group V, anastomosis+rectal ethyl alcohol (1 cc/d). The bursting pressures, hydroxiproline levels and histopathological changes in each group were measured. Results When bursting pressures were compared between groups, we observed that they were increased in the groups treated with propolis in contrast to all other groups. Hydroxiproline levels in the propolis groups were also significantly increased in contrast to the other groups. There was also a statistically significant difference in histopathological changes between the treatment types. When propolis administration methods were compared, we did not observe a statistically significant difference. Conclusion Propolis has a significantly favourable effect on healing in experimental colon anastomosis, independent from the method of administration.

Advances in Therapy, 2007

This study was conducted to investigate the effects of propolis and mesalamine on experimental co... more This study was conducted to investigate the effects of propolis and mesalamine on experimental colitis in rats. Distal colitis was induced in rats by intracolonic instillation of 2 mL of 4% acetic acid. The animals were randomly assigned to 5 groups: group 1, control, (n=8); group 2, colitis, received no treatment (n=8); group 3, colitis+mesalamine, 2 mL once a day via an enema (n=8); group 4, colitis+propolis, 600 mg/kg once a day via intragastric lavage (n=8); and group 5, colitis+ mesalamine+propolis for 1 wk (n=8). Levels of nitric oxide were statistically significantly different in comparisons between groups 1 and 2, groups 2 and 3, and groups 4 and 5. Malondialdehyde levels were significantly different when group 2 was compared with groups 3, 4, and 5. A significant difference was observed when group 3 was compared with group 4 for myeloperoxidase. Most propolis-treated rats had normal histology; mesalamine-treated and propolis+mesalamine-treated rats had inflammatory cell infiltration at rates of 50% and 33%, respectively. The investigators concluded that propolis and mesalamine are efficient independently and in combination, but that their combined effect was not observed to be additive in experimental colitis.

International Journal of Surgery, 2008

Breast Care, 2008

Brustkrebs · Diagnose · Früherkennung · Epidemiologie Zusammenfassung Hintergrund: Ziel dieser St... more Brustkrebs · Diagnose · Früherkennung · Epidemiologie Zusammenfassung Hintergrund: Ziel dieser Studie war die Untersuchung des Wissens, der Einstellung und des Verhaltens von Lehrerinnen in der südlichen Türkei in Bezug auf Brustkrebs. Material und Methoden: Fast 5000 Lehrerinnen sind in Hatay, Türkei tätig. Unser Ziel war es, 10% dieser Population zu erreichen. Unser Fragebogen enthielt 14 personenbezogene Fragen, 14 Fragen zum Wissen um Brustkrebs und 14 Fragen zu Einstellung und Verhalten der Lehrerinnen. Ergebnisse: Insgesamt nahmen 490 Lehrerinnen an der Studie teil. Das Durchschnittsalter betrug 34,6 Jahre, und die Mehrzahl der Teilnehmerinnen war verheiratet (77,1%). 62,9% gaben an, über unzureichendes Wissen bezüglich Brustkrebs zu verfügen. Zu den Informationsquellen gehörten Zeitungen/ Fernsehen in 84,6% der Fälle, und das Gesundheitswesen in 22,8%. Obgleich alle Teilnehmerinnen der Meinung sind, dass Brustkrebsfrüherkennung von Bedeutung ist, glauben 19%, dass Körperpflege vor Brustkrebs schützt. 53,7% der Teilnehmerinnen haben noch nie eine Brustselbstuntersuchung durchgeführt. 80,6% derjenigen, die ihre Brust selbst untersuchen, tun dies wann immer sie daran denken, 12,5% untersuchen sich einmal im Monat. 38,4% haben die Selbstuntersuchung von einem Arzt gelernt, 38,0% aus dem Fernsehen. Gründe, keine Selbstuntersuchung durchzuführen, waren Unterschätzung in 46,7% der Fälle und Unwissen in 37,9%. 152 Teilnehmerinnen haben in der Vergangenheit eine klinische Brustuntersuchung durchführen lassen. 145 dieser Untersuchungen wurden von einem Spezialisten durchgeführt. Eine Mammographie war bei insgesamt 86 Teilnehmerinnen vorgenommen worden. 67 Frauen über 40 Jahren haben bisher an keiner Mammographie teilgenommen. Schlussfolgerung: 3/5 Lehrerinnen meinen, über unzureichendes Wissen bezüglich Brustkrebs zu verfügen. Mehr als die Hälfte führen keine Brustselbstuntersuchung durch, und nur 12,5% tun dies regelmäßig.

Archives of Gynecology and Obstetrics, 2008

Background Accessory ovaries are rare anomalies and cysts arising from accessory ovaries are extr... more Background Accessory ovaries are rare anomalies and cysts arising from accessory ovaries are extremely rare. Their reported incidence is 1/29,000–1/700,000. Establishing the diagnosis preoperatively is difficult. Radiologic methods are usually inadequate in recognizing the origin of these tumors. Thus, they are usually confused with other intraabdominal tumors. Case A 22-year-old nulliparous girl presented with abdominal pain and tumoral growth for 1.5 years. Abdominal ultrasound and computed tomography revealed a 33 × 26 × 15 cm cystic mass filling the abdominal cavity. The preoperative diagnosis was a mesenteric cyst. Diagnostic laparotomy revealed a giant cystic mass arising in an accessory ovary. The left tuba and fimbrias were adhered to the cyst. The tumor was totally removed and fimbrioplasty performed. Conclusion In spite of being rare entities, paraovarian anomalies should be considered in the differential diagnosis of intraabdominal tumors, especially when the origin is not identified by radiologic means. Case A 22-year-old single, nulliparious female was admitted to our hospital with abdominal pain, nausea and a growing abdominal swelling since 1.5 years. A tumoral mass was palpated on physical examination. Abdominal ultrasound and computed tomography revealed a 33 × 26 × 15 cm cystic mass filling the abdominal cavity. The origin of the tumor could not be detected. Operation revealed a giant cystic mass arising from an accessory ovary. Histopathologic diagnosis was serous cystadenoma. Conclusion Ovarian or accessory ovarian pathologies must be considered in the differential diagnosis of intraabdominal tumors, especially in young female population.

Advances in Therapy, 2008

This case report involves a 60-year-old diabetic man who developed septic arthritis as a result o... more This case report involves a 60-year-old diabetic man who developed septic arthritis as a result of the pathogen Morganella morganii. The patient had complaints of elevated body temperature, malaise, rigors and pain in the left knee, despite no history of trauma. On examination of the knee, erythema, warmth, tenderness and swelling was observed. Arthrocentesis performed on his left knee indicated the presence of straw-coloured, cloudy fluid without crystals. Bacterial identification based on biochemical and automated methods indicated the growth of M morganii. M morganii was also isolated sedimentafrom the exudate of a diabetic ulcer in the left foot, with antibiotic susceptibilities identical to those from the knee effusion. This case indicates that M morganii may be considered as a possible cause of septic arthritis in diabetic patients, especially those with diabetic foot infections.

*Ahmet Aslan, Mustafa Kemal Üniv. Tıp Fak., Genel Cerrahi AD, Bağrıyanık M. Antakya, Hatay. Tel: ... more *Ahmet Aslan, Mustafa Kemal Üniv. Tıp Fak., Genel Cerrahi AD, Bağrıyanık M. Antakya, Hatay. Tel: 326.2141649. E-posta: aslan@mku.edu.tr ... Özet: Bu çalışmada, Hemşirelik Yüksekokulu öğrencilerinin meme kanseri hakkındaki bilgi, tutum ve davranışlarının saptanması ...

Breast Care, 2008

17 Praktische Anwendung der klinischen Brustuntersuchung und Brustselbstuntersuchung in der Brust... more 17 Praktische Anwendung der klinischen Brustuntersuchung und Brustselbstuntersuchung in der Brustkrebsvorsorge und Früherkennung Miller, A.B. (Toronto, ON) 21 Betreuung von Brustkrebspatientinnen in Indien: Momentane Gegebenheiten und Herausforderungen für die Zukunft Agarwal, G.; Ramakant, P. (Lucknow) 29 Einführung eines Brustkrebsfrüherkennungsprogrammes in Kolumbien Murillo, R.; Díaz, S.; Sánchez, O.; Perry, F.; Piñeros, M.; Poveda, C.; Salguero, E.; Osorio, D. (Bogota) 33 Pilotprojekt zur Formulierung von auf Checklisten basierenden Empfehlungen für klinische Krebsforschungszentren in Ländern mit beschränkten Mitteln Eniu, A. (Cluj-Napoca) CONTENTS INHALT Breast Care Brauch, H.; Schroth, W.; Eichelbaum, M.; Schwab, M. (Stuttgart, Tübingen); Harbeck, N. (München); in cooperation with the AGO TRAFO Comission Case Report 51 Bilateral Nonsynchronous Male Breast Cancer: Two Case Reports Horimoto, Y.; Hino, M.; Saito, M.; Arakawa, A.; Matsumoto, T.; Kasumi, F. (Tokyo)

ÖZET Gebelikte ileusa neden olan sigmoid kolon kanseri: ‹ki olgunun sunumu Gebelikte kolorektal k... more ÖZET Gebelikte ileusa neden olan sigmoid kolon kanseri: ‹ki olgunun sunumu Gebelikte kolorektal kanser çok nadir olup bildirilen insidans %0.001-0.1'dir. Gecikmifl tan› ve hastal›¤›n ilerlemesi nedeni ile prognozu kötüdür. Sigmoid kolon tümörüne ba¤l› akut bat›n geliflmesi çok nadirdir. Gebelik esnas›nda ileus ile kendini gösteren iki sigmoid kolon kanseri olgusunu literatür eflli¤inde sunduk. Biri 35, di¤eri 32 yafl›nda ve s›ras› ile 32 ve 27 haftal›k gebe iki kad›n hasta kar›n a¤r›s› ve ileus tablosu ile baflvurdular. Her ikisinde de eksploratif laparotomide t›kay›c› sigmoid kolon kanseri tespit edildi. Uterus büyüklü¤ü izin vermedi¤i için vakalar›n birinde kolon mezo disseksiyonu genifl olarak yap›lamad›. Ayn› vakada kolon polipoid lezyonlarla dolu idi. Gebelerde sigmoid kolon tümörüne ba¤l› akut bat›n geliflmesi çok nadirdir ve cerrahi esnas›nda eksplorasyon tam olarak yap›lmazsa tümör kolayl›kla atlanabilir. Klinik flüphe tan›y› koymakta çok önemlidir.

Current Therapeutic Research-clinical and Experimental, 2009

Background: Clinical effects, recovery characteristics, and costs of total intravenous anesthesia... more Background: Clinical effects, recovery characteristics, and costs of total intravenous anesthesia with different inhalational anesthetics have been investigated and compared; however, there are no reported clinical studies focusing on the effects of anesthesia with propofol and desflurane in patients undergoing laparoscopic cholecystectomy.

Advances in Therapy, 2008

Introduction Propolis is the generic name for the resinous substance collected by honeybees, whic... more Introduction Propolis is the generic name for the resinous substance collected by honeybees, which is known to have antioxidant, anti-inflammatory, apoptosis-inducible effects. Anastomotic dehiscence after colorectal surgery is an important cause of morbidity and mortality. We aimed to assess the effect of propolis on healing in an experimental colon anastomosis in rats. Methods Forty adult male Wistar albino rats were randomly assigned into 5 treatment groups with 8 rats in each: Group I, anastomosis+no treatment; Group II, anastomosis+oral propolis (600 mg/kg/d); Group III, anastomosis+oral ethyl alcohol (1 cc/d); Group IV, anastomosis+rectal propolis (600 mg/kg/d); Group V, anastomosis+rectal ethyl alcohol (1 cc/d). The bursting pressures, hydroxiproline levels and histopathological changes in each group were measured. Results When bursting pressures were compared between groups, we observed that they were increased in the groups treated with propolis in contrast to all other groups. Hydroxiproline levels in the propolis groups were also significantly increased in contrast to the other groups. There was also a statistically significant difference in histopathological changes between the treatment types. When propolis administration methods were compared, we did not observe a statistically significant difference. Conclusion Propolis has a significantly favourable effect on healing in experimental colon anastomosis, independent from the method of administration.

Advances in Therapy, 2007

This study was conducted to investigate the effects of propolis and mesalamine on experimental co... more This study was conducted to investigate the effects of propolis and mesalamine on experimental colitis in rats. Distal colitis was induced in rats by intracolonic instillation of 2 mL of 4% acetic acid. The animals were randomly assigned to 5 groups: group 1, control, (n=8); group 2, colitis, received no treatment (n=8); group 3, colitis+mesalamine, 2 mL once a day via an enema (n=8); group 4, colitis+propolis, 600 mg/kg once a day via intragastric lavage (n=8); and group 5, colitis+ mesalamine+propolis for 1 wk (n=8). Levels of nitric oxide were statistically significantly different in comparisons between groups 1 and 2, groups 2 and 3, and groups 4 and 5. Malondialdehyde levels were significantly different when group 2 was compared with groups 3, 4, and 5. A significant difference was observed when group 3 was compared with group 4 for myeloperoxidase. Most propolis-treated rats had normal histology; mesalamine-treated and propolis+mesalamine-treated rats had inflammatory cell infiltration at rates of 50% and 33%, respectively. The investigators concluded that propolis and mesalamine are efficient independently and in combination, but that their combined effect was not observed to be additive in experimental colitis.

International Journal of Surgery, 2008

We aimed to investigate the effect of mesalamine on healing of experimental colon anastomosis mod... more We aimed to investigate the effect of mesalamine on healing of experimental colon anastomosis model.Forty adult male Wistar albino rats were performed segmentary colonic resection and end-to-end anastomosis. Animals were randomly divided into four groups: group I, anastomosis group, received no treatment (GI, n = 8); group II, anastomosis + oral mesalamine group (100 mg/kg/day); group III, anastomosis + rectal mesalamine (2 mL) group, (GIII, n = 8); group IV, anastomosis + oral mesalamine + rectal mesalamine (GIV, n = 8) group. A sham group (n = 8) was constituted and was performed laparotomy. Bursting pressure, hydroxyproline levels and histopathological characteristics of the anastomosis were analyzed.Although it was not statistically significant, there was an increase in the burst pressure of the mesalamine group. When hydroxyproline measurements were compared there were statistically significant difference between the non-treated colon and all groups. There were significant differences between GI and GIII–GIV, GII and GIV. The differences between group I and II and group II and III were not statistically significant.When we compared the median amount of the histopathological changes, we found significant difference between the anastomosis and the mesalamine groups (P < 0.05). But when mesalamine groups were compared with each other we did not observe a significant difference.Mesalamine had positive effects which were not statistically significant on bursting pressure and statistically different significant effects on hydroxyproline (HP) levels based on the way of administration and statistically significant positive effects on histopathologic anastomotic healing in experimental anastomosis model

Breast Care, 2008

Brustkrebs · Diagnose · Früherkennung · Epidemiologie Zusammenfassung Hintergrund: Ziel dieser St... more Brustkrebs · Diagnose · Früherkennung · Epidemiologie Zusammenfassung Hintergrund: Ziel dieser Studie war die Untersuchung des Wissens, der Einstellung und des Verhaltens von Lehrerinnen in der südlichen Türkei in Bezug auf Brustkrebs. Material und Methoden: Fast 5000 Lehrerinnen sind in Hatay, Türkei tätig. Unser Ziel war es, 10% dieser Population zu erreichen. Unser Fragebogen enthielt 14 personenbezogene Fragen, 14 Fragen zum Wissen um Brustkrebs und 14 Fragen zu Einstellung und Verhalten der Lehrerinnen. Ergebnisse: Insgesamt nahmen 490 Lehrerinnen an der Studie teil. Das Durchschnittsalter betrug 34,6 Jahre, und die Mehrzahl der Teilnehmerinnen war verheiratet (77,1%). 62,9% gaben an, über unzureichendes Wissen bezüglich Brustkrebs zu verfügen. Zu den Informationsquellen gehörten Zeitungen/ Fernsehen in 84,6% der Fälle, und das Gesundheitswesen in 22,8%. Obgleich alle Teilnehmerinnen der Meinung sind, dass Brustkrebsfrüherkennung von Bedeutung ist, glauben 19%, dass Körperpflege vor Brustkrebs schützt. 53,7% der Teilnehmerinnen haben noch nie eine Brustselbstuntersuchung durchgeführt. 80,6% derjenigen, die ihre Brust selbst untersuchen, tun dies wann immer sie daran denken, 12,5% untersuchen sich einmal im Monat. 38,4% haben die Selbstuntersuchung von einem Arzt gelernt, 38,0% aus dem Fernsehen. Gründe, keine Selbstuntersuchung durchzuführen, waren Unterschätzung in 46,7% der Fälle und Unwissen in 37,9%. 152 Teilnehmerinnen haben in der Vergangenheit eine klinische Brustuntersuchung durchführen lassen. 145 dieser Untersuchungen wurden von einem Spezialisten durchgeführt. Eine Mammographie war bei insgesamt 86 Teilnehmerinnen vorgenommen worden. 67 Frauen über 40 Jahren haben bisher an keiner Mammographie teilgenommen. Schlussfolgerung: 3/5 Lehrerinnen meinen, über unzureichendes Wissen bezüglich Brustkrebs zu verfügen. Mehr als die Hälfte führen keine Brustselbstuntersuchung durch, und nur 12,5% tun dies regelmäßig.

Archives of Gynecology and Obstetrics, 2008

Background Accessory ovaries are rare anomalies and cysts arising from accessory ovaries are extr... more Background Accessory ovaries are rare anomalies and cysts arising from accessory ovaries are extremely rare. Their reported incidence is 1/29,000–1/700,000. Establishing the diagnosis preoperatively is difficult. Radiologic methods are usually inadequate in recognizing the origin of these tumors. Thus, they are usually confused with other intraabdominal tumors. Case A 22-year-old nulliparous girl presented with abdominal pain and tumoral growth for 1.5 years. Abdominal ultrasound and computed tomography revealed a 33 × 26 × 15 cm cystic mass filling the abdominal cavity. The preoperative diagnosis was a mesenteric cyst. Diagnostic laparotomy revealed a giant cystic mass arising in an accessory ovary. The left tuba and fimbrias were adhered to the cyst. The tumor was totally removed and fimbrioplasty performed. Conclusion In spite of being rare entities, paraovarian anomalies should be considered in the differential diagnosis of intraabdominal tumors, especially when the origin is not identified by radiologic means. Case A 22-year-old single, nulliparious female was admitted to our hospital with abdominal pain, nausea and a growing abdominal swelling since 1.5 years. A tumoral mass was palpated on physical examination. Abdominal ultrasound and computed tomography revealed a 33 × 26 × 15 cm cystic mass filling the abdominal cavity. The origin of the tumor could not be detected. Operation revealed a giant cystic mass arising from an accessory ovary. Histopathologic diagnosis was serous cystadenoma. Conclusion Ovarian or accessory ovarian pathologies must be considered in the differential diagnosis of intraabdominal tumors, especially in young female population.

Advances in Therapy, 2008

This case report involves a 60-year-old diabetic man who developed septic arthritis as a result o... more This case report involves a 60-year-old diabetic man who developed septic arthritis as a result of the pathogen Morganella morganii. The patient had complaints of elevated body temperature, malaise, rigors and pain in the left knee, despite no history of trauma. On examination of the knee, erythema, warmth, tenderness and swelling was observed. Arthrocentesis performed on his left knee indicated the presence of straw-coloured, cloudy fluid without crystals. Bacterial identification based on biochemical and automated methods indicated the growth of M morganii. M morganii was also isolated sedimentafrom the exudate of a diabetic ulcer in the left foot, with antibiotic susceptibilities identical to those from the knee effusion. This case indicates that M morganii may be considered as a possible cause of septic arthritis in diabetic patients, especially those with diabetic foot infections.

*Ahmet Aslan, Mustafa Kemal Üniv. Tıp Fak., Genel Cerrahi AD, Bağrıyanık M. Antakya, Hatay. Tel: ... more *Ahmet Aslan, Mustafa Kemal Üniv. Tıp Fak., Genel Cerrahi AD, Bağrıyanık M. Antakya, Hatay. Tel: 326.2141649. E-posta: aslan@mku.edu.tr ... Özet: Bu çalışmada, Hemşirelik Yüksekokulu öğrencilerinin meme kanseri hakkındaki bilgi, tutum ve davranışlarının saptanması ...

Breast Care, 2008

17 Praktische Anwendung der klinischen Brustuntersuchung und Brustselbstuntersuchung in der Brust... more 17 Praktische Anwendung der klinischen Brustuntersuchung und Brustselbstuntersuchung in der Brustkrebsvorsorge und Früherkennung Miller, A.B. (Toronto, ON) 21 Betreuung von Brustkrebspatientinnen in Indien: Momentane Gegebenheiten und Herausforderungen für die Zukunft Agarwal, G.; Ramakant, P. (Lucknow) 29 Einführung eines Brustkrebsfrüherkennungsprogrammes in Kolumbien Murillo, R.; Díaz, S.; Sánchez, O.; Perry, F.; Piñeros, M.; Poveda, C.; Salguero, E.; Osorio, D. (Bogota) 33 Pilotprojekt zur Formulierung von auf Checklisten basierenden Empfehlungen für klinische Krebsforschungszentren in Ländern mit beschränkten Mitteln Eniu, A. (Cluj-Napoca) CONTENTS INHALT Breast Care Brauch, H.; Schroth, W.; Eichelbaum, M.; Schwab, M. (Stuttgart, Tübingen); Harbeck, N. (München); in cooperation with the AGO TRAFO Comission Case Report 51 Bilateral Nonsynchronous Male Breast Cancer: Two Case Reports Horimoto, Y.; Hino, M.; Saito, M.; Arakawa, A.; Matsumoto, T.; Kasumi, F. (Tokyo)

ÖZET Gebelikte ileusa neden olan sigmoid kolon kanseri: ‹ki olgunun sunumu Gebelikte kolorektal k... more ÖZET Gebelikte ileusa neden olan sigmoid kolon kanseri: ‹ki olgunun sunumu Gebelikte kolorektal kanser çok nadir olup bildirilen insidans %0.001-0.1'dir. Gecikmifl tan› ve hastal›¤›n ilerlemesi nedeni ile prognozu kötüdür. Sigmoid kolon tümörüne ba¤l› akut bat›n geliflmesi çok nadirdir. Gebelik esnas›nda ileus ile kendini gösteren iki sigmoid kolon kanseri olgusunu literatür eflli¤inde sunduk. Biri 35, di¤eri 32 yafl›nda ve s›ras› ile 32 ve 27 haftal›k gebe iki kad›n hasta kar›n a¤r›s› ve ileus tablosu ile baflvurdular. Her ikisinde de eksploratif laparotomide t›kay›c› sigmoid kolon kanseri tespit edildi. Uterus büyüklü¤ü izin vermedi¤i için vakalar›n birinde kolon mezo disseksiyonu genifl olarak yap›lamad›. Ayn› vakada kolon polipoid lezyonlarla dolu idi. Gebelerde sigmoid kolon tümörüne ba¤l› akut bat›n geliflmesi çok nadirdir ve cerrahi esnas›nda eksplorasyon tam olarak yap›lmazsa tümör kolayl›kla atlanabilir. Klinik flüphe tan›y› koymakta çok önemlidir.

Case Reports in Gastroenterology, 2008

Hepatic tuberculosis is a rare manifestation of extra-pulmonary tuberculosis. Hepatic tuberculous... more Hepatic tuberculosis is a rare manifestation of extra-pulmonary tuberculosis. Hepatic tuberculous lesions are especially mimicking tumour-like mass or cystic lesions in the liver and so can be misdiagnosed with several diseases. Histopathological examination of the specimen is essential in the diagnosis for hepatic tuberculosis. In this report, two cases with hepatic tuberculosis having cystic solid mass and abscess liver lesions are described.

Advances in Therapy, 2008

Introduction Propolis is the generic name for the resinous substance collected by honeybees, whic... more Introduction Propolis is the generic name for the resinous substance collected by honeybees, which is known to have antioxidant, anti-inflammatory, apoptosis-inducible effects. Anastomotic dehiscence after colorectal surgery is an important cause of morbidity and mortality. We aimed to assess the effect of propolis on healing in an experimental colon anastomosis in rats. Methods Forty adult male Wistar albino rats were randomly assigned into 5 treatment groups with 8 rats in each: Group I, anastomosis+no treatment; Group II, anastomosis+oral propolis (600 mg/kg/d); Group III, anastomosis+oral ethyl alcohol (1 cc/d); Group IV, anastomosis+rectal propolis (600 mg/kg/d); Group V, anastomosis+rectal ethyl alcohol (1 cc/d). The bursting pressures, hydroxiproline levels and histopathological changes in each group were measured. Results When bursting pressures were compared between groups, we observed that they were increased in the groups treated with propolis in contrast to all other groups. Hydroxiproline levels in the propolis groups were also significantly increased in contrast to the other groups. There was also a statistically significant difference in histopathological changes between the treatment types. When propolis administration methods were compared, we did not observe a statistically significant difference. Conclusion Propolis has a significantly favourable effect on healing in experimental colon anastomosis, independent from the method of administration.

Advances in Therapy, 2007

This study was conducted to investigate the effects of propolis and mesalamine on experimental co... more This study was conducted to investigate the effects of propolis and mesalamine on experimental colitis in rats. Distal colitis was induced in rats by intracolonic instillation of 2 mL of 4% acetic acid. The animals were randomly assigned to 5 groups: group 1, control, (n=8); group 2, colitis, received no treatment (n=8); group 3, colitis+mesalamine, 2 mL once a day via an enema (n=8); group 4, colitis+propolis, 600 mg/kg once a day via intragastric lavage (n=8); and group 5, colitis+ mesalamine+propolis for 1 wk (n=8). Levels of nitric oxide were statistically significantly different in comparisons between groups 1 and 2, groups 2 and 3, and groups 4 and 5. Malondialdehyde levels were significantly different when group 2 was compared with groups 3, 4, and 5. A significant difference was observed when group 3 was compared with group 4 for myeloperoxidase. Most propolis-treated rats had normal histology; mesalamine-treated and propolis+mesalamine-treated rats had inflammatory cell infiltration at rates of 50% and 33%, respectively. The investigators concluded that propolis and mesalamine are efficient independently and in combination, but that their combined effect was not observed to be additive in experimental colitis.

International Journal of Surgery, 2008

Breast Care, 2008

Brustkrebs · Diagnose · Früherkennung · Epidemiologie Zusammenfassung Hintergrund: Ziel dieser St... more Brustkrebs · Diagnose · Früherkennung · Epidemiologie Zusammenfassung Hintergrund: Ziel dieser Studie war die Untersuchung des Wissens, der Einstellung und des Verhaltens von Lehrerinnen in der südlichen Türkei in Bezug auf Brustkrebs. Material und Methoden: Fast 5000 Lehrerinnen sind in Hatay, Türkei tätig. Unser Ziel war es, 10% dieser Population zu erreichen. Unser Fragebogen enthielt 14 personenbezogene Fragen, 14 Fragen zum Wissen um Brustkrebs und 14 Fragen zu Einstellung und Verhalten der Lehrerinnen. Ergebnisse: Insgesamt nahmen 490 Lehrerinnen an der Studie teil. Das Durchschnittsalter betrug 34,6 Jahre, und die Mehrzahl der Teilnehmerinnen war verheiratet (77,1%). 62,9% gaben an, über unzureichendes Wissen bezüglich Brustkrebs zu verfügen. Zu den Informationsquellen gehörten Zeitungen/ Fernsehen in 84,6% der Fälle, und das Gesundheitswesen in 22,8%. Obgleich alle Teilnehmerinnen der Meinung sind, dass Brustkrebsfrüherkennung von Bedeutung ist, glauben 19%, dass Körperpflege vor Brustkrebs schützt. 53,7% der Teilnehmerinnen haben noch nie eine Brustselbstuntersuchung durchgeführt. 80,6% derjenigen, die ihre Brust selbst untersuchen, tun dies wann immer sie daran denken, 12,5% untersuchen sich einmal im Monat. 38,4% haben die Selbstuntersuchung von einem Arzt gelernt, 38,0% aus dem Fernsehen. Gründe, keine Selbstuntersuchung durchzuführen, waren Unterschätzung in 46,7% der Fälle und Unwissen in 37,9%. 152 Teilnehmerinnen haben in der Vergangenheit eine klinische Brustuntersuchung durchführen lassen. 145 dieser Untersuchungen wurden von einem Spezialisten durchgeführt. Eine Mammographie war bei insgesamt 86 Teilnehmerinnen vorgenommen worden. 67 Frauen über 40 Jahren haben bisher an keiner Mammographie teilgenommen. Schlussfolgerung: 3/5 Lehrerinnen meinen, über unzureichendes Wissen bezüglich Brustkrebs zu verfügen. Mehr als die Hälfte führen keine Brustselbstuntersuchung durch, und nur 12,5% tun dies regelmäßig.

Archives of Gynecology and Obstetrics, 2008

Background Accessory ovaries are rare anomalies and cysts arising from accessory ovaries are extr... more Background Accessory ovaries are rare anomalies and cysts arising from accessory ovaries are extremely rare. Their reported incidence is 1/29,000–1/700,000. Establishing the diagnosis preoperatively is difficult. Radiologic methods are usually inadequate in recognizing the origin of these tumors. Thus, they are usually confused with other intraabdominal tumors. Case A 22-year-old nulliparous girl presented with abdominal pain and tumoral growth for 1.5 years. Abdominal ultrasound and computed tomography revealed a 33 × 26 × 15 cm cystic mass filling the abdominal cavity. The preoperative diagnosis was a mesenteric cyst. Diagnostic laparotomy revealed a giant cystic mass arising in an accessory ovary. The left tuba and fimbrias were adhered to the cyst. The tumor was totally removed and fimbrioplasty performed. Conclusion In spite of being rare entities, paraovarian anomalies should be considered in the differential diagnosis of intraabdominal tumors, especially when the origin is not identified by radiologic means. Case A 22-year-old single, nulliparious female was admitted to our hospital with abdominal pain, nausea and a growing abdominal swelling since 1.5 years. A tumoral mass was palpated on physical examination. Abdominal ultrasound and computed tomography revealed a 33 × 26 × 15 cm cystic mass filling the abdominal cavity. The origin of the tumor could not be detected. Operation revealed a giant cystic mass arising from an accessory ovary. Histopathologic diagnosis was serous cystadenoma. Conclusion Ovarian or accessory ovarian pathologies must be considered in the differential diagnosis of intraabdominal tumors, especially in young female population.

Advances in Therapy, 2008

This case report involves a 60-year-old diabetic man who developed septic arthritis as a result o... more This case report involves a 60-year-old diabetic man who developed septic arthritis as a result of the pathogen Morganella morganii. The patient had complaints of elevated body temperature, malaise, rigors and pain in the left knee, despite no history of trauma. On examination of the knee, erythema, warmth, tenderness and swelling was observed. Arthrocentesis performed on his left knee indicated the presence of straw-coloured, cloudy fluid without crystals. Bacterial identification based on biochemical and automated methods indicated the growth of M morganii. M morganii was also isolated sedimentafrom the exudate of a diabetic ulcer in the left foot, with antibiotic susceptibilities identical to those from the knee effusion. This case indicates that M morganii may be considered as a possible cause of septic arthritis in diabetic patients, especially those with diabetic foot infections.

*Ahmet Aslan, Mustafa Kemal Üniv. Tıp Fak., Genel Cerrahi AD, Bağrıyanık M. Antakya, Hatay. Tel: ... more *Ahmet Aslan, Mustafa Kemal Üniv. Tıp Fak., Genel Cerrahi AD, Bağrıyanık M. Antakya, Hatay. Tel: 326.2141649. E-posta: aslan@mku.edu.tr ... Özet: Bu çalışmada, Hemşirelik Yüksekokulu öğrencilerinin meme kanseri hakkındaki bilgi, tutum ve davranışlarının saptanması ...

Breast Care, 2008

17 Praktische Anwendung der klinischen Brustuntersuchung und Brustselbstuntersuchung in der Brust... more 17 Praktische Anwendung der klinischen Brustuntersuchung und Brustselbstuntersuchung in der Brustkrebsvorsorge und Früherkennung Miller, A.B. (Toronto, ON) 21 Betreuung von Brustkrebspatientinnen in Indien: Momentane Gegebenheiten und Herausforderungen für die Zukunft Agarwal, G.; Ramakant, P. (Lucknow) 29 Einführung eines Brustkrebsfrüherkennungsprogrammes in Kolumbien Murillo, R.; Díaz, S.; Sánchez, O.; Perry, F.; Piñeros, M.; Poveda, C.; Salguero, E.; Osorio, D. (Bogota) 33 Pilotprojekt zur Formulierung von auf Checklisten basierenden Empfehlungen für klinische Krebsforschungszentren in Ländern mit beschränkten Mitteln Eniu, A. (Cluj-Napoca) CONTENTS INHALT Breast Care Brauch, H.; Schroth, W.; Eichelbaum, M.; Schwab, M. (Stuttgart, Tübingen); Harbeck, N. (München); in cooperation with the AGO TRAFO Comission Case Report 51 Bilateral Nonsynchronous Male Breast Cancer: Two Case Reports Horimoto, Y.; Hino, M.; Saito, M.; Arakawa, A.; Matsumoto, T.; Kasumi, F. (Tokyo)

ÖZET Gebelikte ileusa neden olan sigmoid kolon kanseri: ‹ki olgunun sunumu Gebelikte kolorektal k... more ÖZET Gebelikte ileusa neden olan sigmoid kolon kanseri: ‹ki olgunun sunumu Gebelikte kolorektal kanser çok nadir olup bildirilen insidans %0.001-0.1'dir. Gecikmifl tan› ve hastal›¤›n ilerlemesi nedeni ile prognozu kötüdür. Sigmoid kolon tümörüne ba¤l› akut bat›n geliflmesi çok nadirdir. Gebelik esnas›nda ileus ile kendini gösteren iki sigmoid kolon kanseri olgusunu literatür eflli¤inde sunduk. Biri 35, di¤eri 32 yafl›nda ve s›ras› ile 32 ve 27 haftal›k gebe iki kad›n hasta kar›n a¤r›s› ve ileus tablosu ile baflvurdular. Her ikisinde de eksploratif laparotomide t›kay›c› sigmoid kolon kanseri tespit edildi. Uterus büyüklü¤ü izin vermedi¤i için vakalar›n birinde kolon mezo disseksiyonu genifl olarak yap›lamad›. Ayn› vakada kolon polipoid lezyonlarla dolu idi. Gebelerde sigmoid kolon tümörüne ba¤l› akut bat›n geliflmesi çok nadirdir ve cerrahi esnas›nda eksplorasyon tam olarak yap›lmazsa tümör kolayl›kla atlanabilir. Klinik flüphe tan›y› koymakta çok önemlidir.

Current Therapeutic Research-clinical and Experimental, 2009

Background: Clinical effects, recovery characteristics, and costs of total intravenous anesthesia... more Background: Clinical effects, recovery characteristics, and costs of total intravenous anesthesia with different inhalational anesthetics have been investigated and compared; however, there are no reported clinical studies focusing on the effects of anesthesia with propofol and desflurane in patients undergoing laparoscopic cholecystectomy.

Advances in Therapy, 2008

Introduction Propolis is the generic name for the resinous substance collected by honeybees, whic... more Introduction Propolis is the generic name for the resinous substance collected by honeybees, which is known to have antioxidant, anti-inflammatory, apoptosis-inducible effects. Anastomotic dehiscence after colorectal surgery is an important cause of morbidity and mortality. We aimed to assess the effect of propolis on healing in an experimental colon anastomosis in rats. Methods Forty adult male Wistar albino rats were randomly assigned into 5 treatment groups with 8 rats in each: Group I, anastomosis+no treatment; Group II, anastomosis+oral propolis (600 mg/kg/d); Group III, anastomosis+oral ethyl alcohol (1 cc/d); Group IV, anastomosis+rectal propolis (600 mg/kg/d); Group V, anastomosis+rectal ethyl alcohol (1 cc/d). The bursting pressures, hydroxiproline levels and histopathological changes in each group were measured. Results When bursting pressures were compared between groups, we observed that they were increased in the groups treated with propolis in contrast to all other groups. Hydroxiproline levels in the propolis groups were also significantly increased in contrast to the other groups. There was also a statistically significant difference in histopathological changes between the treatment types. When propolis administration methods were compared, we did not observe a statistically significant difference. Conclusion Propolis has a significantly favourable effect on healing in experimental colon anastomosis, independent from the method of administration.

Advances in Therapy, 2007

This study was conducted to investigate the effects of propolis and mesalamine on experimental co... more This study was conducted to investigate the effects of propolis and mesalamine on experimental colitis in rats. Distal colitis was induced in rats by intracolonic instillation of 2 mL of 4% acetic acid. The animals were randomly assigned to 5 groups: group 1, control, (n=8); group 2, colitis, received no treatment (n=8); group 3, colitis+mesalamine, 2 mL once a day via an enema (n=8); group 4, colitis+propolis, 600 mg/kg once a day via intragastric lavage (n=8); and group 5, colitis+ mesalamine+propolis for 1 wk (n=8). Levels of nitric oxide were statistically significantly different in comparisons between groups 1 and 2, groups 2 and 3, and groups 4 and 5. Malondialdehyde levels were significantly different when group 2 was compared with groups 3, 4, and 5. A significant difference was observed when group 3 was compared with group 4 for myeloperoxidase. Most propolis-treated rats had normal histology; mesalamine-treated and propolis+mesalamine-treated rats had inflammatory cell infiltration at rates of 50% and 33%, respectively. The investigators concluded that propolis and mesalamine are efficient independently and in combination, but that their combined effect was not observed to be additive in experimental colitis.

International Journal of Surgery, 2008

We aimed to investigate the effect of mesalamine on healing of experimental colon anastomosis mod... more We aimed to investigate the effect of mesalamine on healing of experimental colon anastomosis model.Forty adult male Wistar albino rats were performed segmentary colonic resection and end-to-end anastomosis. Animals were randomly divided into four groups: group I, anastomosis group, received no treatment (GI, n = 8); group II, anastomosis + oral mesalamine group (100 mg/kg/day); group III, anastomosis + rectal mesalamine (2 mL) group, (GIII, n = 8); group IV, anastomosis + oral mesalamine + rectal mesalamine (GIV, n = 8) group. A sham group (n = 8) was constituted and was performed laparotomy. Bursting pressure, hydroxyproline levels and histopathological characteristics of the anastomosis were analyzed.Although it was not statistically significant, there was an increase in the burst pressure of the mesalamine group. When hydroxyproline measurements were compared there were statistically significant difference between the non-treated colon and all groups. There were significant differences between GI and GIII–GIV, GII and GIV. The differences between group I and II and group II and III were not statistically significant.When we compared the median amount of the histopathological changes, we found significant difference between the anastomosis and the mesalamine groups (P < 0.05). But when mesalamine groups were compared with each other we did not observe a significant difference.Mesalamine had positive effects which were not statistically significant on bursting pressure and statistically different significant effects on hydroxyproline (HP) levels based on the way of administration and statistically significant positive effects on histopathologic anastomotic healing in experimental anastomosis model

Breast Care, 2008

Brustkrebs · Diagnose · Früherkennung · Epidemiologie Zusammenfassung Hintergrund: Ziel dieser St... more Brustkrebs · Diagnose · Früherkennung · Epidemiologie Zusammenfassung Hintergrund: Ziel dieser Studie war die Untersuchung des Wissens, der Einstellung und des Verhaltens von Lehrerinnen in der südlichen Türkei in Bezug auf Brustkrebs. Material und Methoden: Fast 5000 Lehrerinnen sind in Hatay, Türkei tätig. Unser Ziel war es, 10% dieser Population zu erreichen. Unser Fragebogen enthielt 14 personenbezogene Fragen, 14 Fragen zum Wissen um Brustkrebs und 14 Fragen zu Einstellung und Verhalten der Lehrerinnen. Ergebnisse: Insgesamt nahmen 490 Lehrerinnen an der Studie teil. Das Durchschnittsalter betrug 34,6 Jahre, und die Mehrzahl der Teilnehmerinnen war verheiratet (77,1%). 62,9% gaben an, über unzureichendes Wissen bezüglich Brustkrebs zu verfügen. Zu den Informationsquellen gehörten Zeitungen/ Fernsehen in 84,6% der Fälle, und das Gesundheitswesen in 22,8%. Obgleich alle Teilnehmerinnen der Meinung sind, dass Brustkrebsfrüherkennung von Bedeutung ist, glauben 19%, dass Körperpflege vor Brustkrebs schützt. 53,7% der Teilnehmerinnen haben noch nie eine Brustselbstuntersuchung durchgeführt. 80,6% derjenigen, die ihre Brust selbst untersuchen, tun dies wann immer sie daran denken, 12,5% untersuchen sich einmal im Monat. 38,4% haben die Selbstuntersuchung von einem Arzt gelernt, 38,0% aus dem Fernsehen. Gründe, keine Selbstuntersuchung durchzuführen, waren Unterschätzung in 46,7% der Fälle und Unwissen in 37,9%. 152 Teilnehmerinnen haben in der Vergangenheit eine klinische Brustuntersuchung durchführen lassen. 145 dieser Untersuchungen wurden von einem Spezialisten durchgeführt. Eine Mammographie war bei insgesamt 86 Teilnehmerinnen vorgenommen worden. 67 Frauen über 40 Jahren haben bisher an keiner Mammographie teilgenommen. Schlussfolgerung: 3/5 Lehrerinnen meinen, über unzureichendes Wissen bezüglich Brustkrebs zu verfügen. Mehr als die Hälfte führen keine Brustselbstuntersuchung durch, und nur 12,5% tun dies regelmäßig.

Archives of Gynecology and Obstetrics, 2008

Background Accessory ovaries are rare anomalies and cysts arising from accessory ovaries are extr... more Background Accessory ovaries are rare anomalies and cysts arising from accessory ovaries are extremely rare. Their reported incidence is 1/29,000–1/700,000. Establishing the diagnosis preoperatively is difficult. Radiologic methods are usually inadequate in recognizing the origin of these tumors. Thus, they are usually confused with other intraabdominal tumors. Case A 22-year-old nulliparous girl presented with abdominal pain and tumoral growth for 1.5 years. Abdominal ultrasound and computed tomography revealed a 33 × 26 × 15 cm cystic mass filling the abdominal cavity. The preoperative diagnosis was a mesenteric cyst. Diagnostic laparotomy revealed a giant cystic mass arising in an accessory ovary. The left tuba and fimbrias were adhered to the cyst. The tumor was totally removed and fimbrioplasty performed. Conclusion In spite of being rare entities, paraovarian anomalies should be considered in the differential diagnosis of intraabdominal tumors, especially when the origin is not identified by radiologic means. Case A 22-year-old single, nulliparious female was admitted to our hospital with abdominal pain, nausea and a growing abdominal swelling since 1.5 years. A tumoral mass was palpated on physical examination. Abdominal ultrasound and computed tomography revealed a 33 × 26 × 15 cm cystic mass filling the abdominal cavity. The origin of the tumor could not be detected. Operation revealed a giant cystic mass arising from an accessory ovary. Histopathologic diagnosis was serous cystadenoma. Conclusion Ovarian or accessory ovarian pathologies must be considered in the differential diagnosis of intraabdominal tumors, especially in young female population.

Advances in Therapy, 2008

This case report involves a 60-year-old diabetic man who developed septic arthritis as a result o... more This case report involves a 60-year-old diabetic man who developed septic arthritis as a result of the pathogen Morganella morganii. The patient had complaints of elevated body temperature, malaise, rigors and pain in the left knee, despite no history of trauma. On examination of the knee, erythema, warmth, tenderness and swelling was observed. Arthrocentesis performed on his left knee indicated the presence of straw-coloured, cloudy fluid without crystals. Bacterial identification based on biochemical and automated methods indicated the growth of M morganii. M morganii was also isolated sedimentafrom the exudate of a diabetic ulcer in the left foot, with antibiotic susceptibilities identical to those from the knee effusion. This case indicates that M morganii may be considered as a possible cause of septic arthritis in diabetic patients, especially those with diabetic foot infections.

*Ahmet Aslan, Mustafa Kemal Üniv. Tıp Fak., Genel Cerrahi AD, Bağrıyanık M. Antakya, Hatay. Tel: ... more *Ahmet Aslan, Mustafa Kemal Üniv. Tıp Fak., Genel Cerrahi AD, Bağrıyanık M. Antakya, Hatay. Tel: 326.2141649. E-posta: aslan@mku.edu.tr ... Özet: Bu çalışmada, Hemşirelik Yüksekokulu öğrencilerinin meme kanseri hakkındaki bilgi, tutum ve davranışlarının saptanması ...

Breast Care, 2008

17 Praktische Anwendung der klinischen Brustuntersuchung und Brustselbstuntersuchung in der Brust... more 17 Praktische Anwendung der klinischen Brustuntersuchung und Brustselbstuntersuchung in der Brustkrebsvorsorge und Früherkennung Miller, A.B. (Toronto, ON) 21 Betreuung von Brustkrebspatientinnen in Indien: Momentane Gegebenheiten und Herausforderungen für die Zukunft Agarwal, G.; Ramakant, P. (Lucknow) 29 Einführung eines Brustkrebsfrüherkennungsprogrammes in Kolumbien Murillo, R.; Díaz, S.; Sánchez, O.; Perry, F.; Piñeros, M.; Poveda, C.; Salguero, E.; Osorio, D. (Bogota) 33 Pilotprojekt zur Formulierung von auf Checklisten basierenden Empfehlungen für klinische Krebsforschungszentren in Ländern mit beschränkten Mitteln Eniu, A. (Cluj-Napoca) CONTENTS INHALT Breast Care Brauch, H.; Schroth, W.; Eichelbaum, M.; Schwab, M. (Stuttgart, Tübingen); Harbeck, N. (München); in cooperation with the AGO TRAFO Comission Case Report 51 Bilateral Nonsynchronous Male Breast Cancer: Two Case Reports Horimoto, Y.; Hino, M.; Saito, M.; Arakawa, A.; Matsumoto, T.; Kasumi, F. (Tokyo)

ÖZET Gebelikte ileusa neden olan sigmoid kolon kanseri: ‹ki olgunun sunumu Gebelikte kolorektal k... more ÖZET Gebelikte ileusa neden olan sigmoid kolon kanseri: ‹ki olgunun sunumu Gebelikte kolorektal kanser çok nadir olup bildirilen insidans %0.001-0.1'dir. Gecikmifl tan› ve hastal›¤›n ilerlemesi nedeni ile prognozu kötüdür. Sigmoid kolon tümörüne ba¤l› akut bat›n geliflmesi çok nadirdir. Gebelik esnas›nda ileus ile kendini gösteren iki sigmoid kolon kanseri olgusunu literatür eflli¤inde sunduk. Biri 35, di¤eri 32 yafl›nda ve s›ras› ile 32 ve 27 haftal›k gebe iki kad›n hasta kar›n a¤r›s› ve ileus tablosu ile baflvurdular. Her ikisinde de eksploratif laparotomide t›kay›c› sigmoid kolon kanseri tespit edildi. Uterus büyüklü¤ü izin vermedi¤i için vakalar›n birinde kolon mezo disseksiyonu genifl olarak yap›lamad›. Ayn› vakada kolon polipoid lezyonlarla dolu idi. Gebelerde sigmoid kolon tümörüne ba¤l› akut bat›n geliflmesi çok nadirdir ve cerrahi esnas›nda eksplorasyon tam olarak yap›lmazsa tümör kolayl›kla atlanabilir. Klinik flüphe tan›y› koymakta çok önemlidir.