Alba Avila - Academia.edu (original) (raw)
Papers by Alba Avila
Revista De Ingenieria, Nov 1, 2004
An experimental method was developed in order to join in vivo fibroblasts to an electronic device... more An experimental method was developed in order to join in vivo fibroblasts to an electronic device, a field effect transistor (ISFET), attempting to give a general view of the implications and requirements of animal cell culture and the different techniques required to handle the ...
Journal of Biomedical Materials Research Part A, 2016
Bacterial cellulose (BC) has been used as a scaffold for tissue regeneration (TR). Improving func... more Bacterial cellulose (BC) has been used as a scaffold for tissue regeneration (TR). Improving functional TR requires highly selective strategies for specific cell attraction. Embedding iron oxide nanoparticles into a BC matrix can drive magnetically labeled cells to specific tissues where they may begin to heal injured tissue. This article focuses on characterization and in vitro toxicity assessment of magnetic BC (MBC). We proposed to detect the production of radical oxygen species (ROS), esterase activity, and apoptosis to study cytotoxic interactions of MBC within its bioenvironment. Morphological characterization was performed using scanning electron microscopy where evidence shows that the diameter of MBC fibers compared to BC fibers was 33% smaller, and the pore areas were 25% bigger. Cytotoxicity assays in porcine aortic smooth muscle cells exposed for 24 hours to BC, MBC, and poly(ethylene glycol)-coated MBC (MBC-PEG) reveals 96% viability and 9% ROS production for MBC-PEG. In contrast, 25% of cells exposed to MBC were apoptotic, suggesting that even when the cells were metabolically active, MBC can induce damage. These outcomes support the need for more integral assessment in the hopes of assessing the potential biosafety and uses of nanocomposites for TR. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 00B:000-000, 2016.
Critical Reviews in Solid State and Materials Sciences, Feb 5, 2010
... Bhushan b pages 38-51. ... The inset shows the AFM's operating modes: contact, noncontac... more ... Bhushan b pages 38-51. ... The inset shows the AFM's operating modes: contact, noncontact, and tapping mode. (Reprinted with kind permission from Bhushan, 3 3. Bhushan, B. 2007. Springer Handbook of Nanotechnology, , 2nd ed., Heidelberg, , Germany: Springer-Verlag. ...
Ingenieria E Investigacion, Mar 17, 2015
Revista De Ingenieria, May 1, 2008
Revista De Ingenieria, May 1, 2008
Page 1. 43 técnica #27 revista de ingeniería. Universidad de los Andes. Bogotá, Colombia. rev.ing... more Page 1. 43 técnica #27 revista de ingeniería. Universidad de los Andes. Bogotá, Colombia. rev.ing. ISSN. 0121-4993. Mayo de 2008 Reproducible Fabrication of Scanning Tunneling Microscope Tips Fabricación reproducible de puntas de barrido para ...
Revista Facultad De Ingenieria, Dec 1, 2010
La microscopía de fuerza electrostática es una técnica de medición de propiedades eléctricas loca... more La microscopía de fuerza electrostática es una técnica de medición de propiedades eléctricas locales de materiales. Las mediciones de gradiente de fuerza eléctrica sobre muestras dieléctricas son sensibles no sólo a la distribución de carga inicial en la misma sino también a la ...
Mundo Nano Revista Interdisciplinaria En Nanociencia Y Nanotecnologia, Oct 3, 2014
Revista De Ingenieria, Nov 1, 2004
Revista Facultad De Ingenieria, Jan 17, 2014
Revista De Ingenieria, May 1, 2005
Momento Revista De Fisica, Dec 19, 2013
Revista De Ingenieria, May 1, 2005
Revista Facultad De Ingenieria Universidad De Antioquia, 2009
Revista De Ingenieria, May 1, 2007
Revista Colombiana De Materiales, May 19, 2014
Http Dx Doi Org 10 1080 10807039 2012 740653, Feb 6, 2014
ABSTRACT The database analysis allows the return of experience needed to support decision-making ... more ABSTRACT The database analysis allows the return of experience needed to support decision-making processes in risk management. A Colombian toxicological database (TED) developed and maintained by the Center of Safety Information and Chemical Products (CISPROQUIM by its Spanish abbreviation in) is analyzed here using a demographic clustering technique. Data-quality processes were performed on the raw data (more than 170 variables) and as a result the database was reduced to 20 meaningful variables. The variables characterized by values with categories were selected for clustering analysis: gender, age, type of emergency, emergency location, means of poisoning, product use, and physical state of the toxic substance. Clustering analysis showed that there are three profiles that are prevalent in the TED database: Young Adult Suicidal Woman, Unsupervised Child, and Man at Work. These profiles could not be identified using traditional statistical analyses performed on the data collected by CISPROQUIM or defined a priori from the categorical variables. The identification of vulnerable populations and the cause of the toxicological events are critical in order to develop national prevention programs and policies. The analysis described provided a methodology for a critical analysis of toxicological databases that can be applied to other databases such as security databases.
Revista De Ingenieria, May 1, 2007
Revista De Ingenieria, Nov 1, 2004
An experimental method was developed in order to join in vivo fibroblasts to an electronic device... more An experimental method was developed in order to join in vivo fibroblasts to an electronic device, a field effect transistor (ISFET), attempting to give a general view of the implications and requirements of animal cell culture and the different techniques required to handle the ...
Journal of Biomedical Materials Research Part A, 2016
Bacterial cellulose (BC) has been used as a scaffold for tissue regeneration (TR). Improving func... more Bacterial cellulose (BC) has been used as a scaffold for tissue regeneration (TR). Improving functional TR requires highly selective strategies for specific cell attraction. Embedding iron oxide nanoparticles into a BC matrix can drive magnetically labeled cells to specific tissues where they may begin to heal injured tissue. This article focuses on characterization and in vitro toxicity assessment of magnetic BC (MBC). We proposed to detect the production of radical oxygen species (ROS), esterase activity, and apoptosis to study cytotoxic interactions of MBC within its bioenvironment. Morphological characterization was performed using scanning electron microscopy where evidence shows that the diameter of MBC fibers compared to BC fibers was 33% smaller, and the pore areas were 25% bigger. Cytotoxicity assays in porcine aortic smooth muscle cells exposed for 24 hours to BC, MBC, and poly(ethylene glycol)-coated MBC (MBC-PEG) reveals 96% viability and 9% ROS production for MBC-PEG. In contrast, 25% of cells exposed to MBC were apoptotic, suggesting that even when the cells were metabolically active, MBC can induce damage. These outcomes support the need for more integral assessment in the hopes of assessing the potential biosafety and uses of nanocomposites for TR. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 00B:000-000, 2016.
Critical Reviews in Solid State and Materials Sciences, Feb 5, 2010
... Bhushan b pages 38-51. ... The inset shows the AFM's operating modes: contact, noncontac... more ... Bhushan b pages 38-51. ... The inset shows the AFM's operating modes: contact, noncontact, and tapping mode. (Reprinted with kind permission from Bhushan, 3 3. Bhushan, B. 2007. Springer Handbook of Nanotechnology, , 2nd ed., Heidelberg, , Germany: Springer-Verlag. ...
Ingenieria E Investigacion, Mar 17, 2015
Revista De Ingenieria, May 1, 2008
Revista De Ingenieria, May 1, 2008
Page 1. 43 técnica #27 revista de ingeniería. Universidad de los Andes. Bogotá, Colombia. rev.ing... more Page 1. 43 técnica #27 revista de ingeniería. Universidad de los Andes. Bogotá, Colombia. rev.ing. ISSN. 0121-4993. Mayo de 2008 Reproducible Fabrication of Scanning Tunneling Microscope Tips Fabricación reproducible de puntas de barrido para ...
Revista Facultad De Ingenieria, Dec 1, 2010
La microscopía de fuerza electrostática es una técnica de medición de propiedades eléctricas loca... more La microscopía de fuerza electrostática es una técnica de medición de propiedades eléctricas locales de materiales. Las mediciones de gradiente de fuerza eléctrica sobre muestras dieléctricas son sensibles no sólo a la distribución de carga inicial en la misma sino también a la ...
Mundo Nano Revista Interdisciplinaria En Nanociencia Y Nanotecnologia, Oct 3, 2014
Revista De Ingenieria, Nov 1, 2004
Revista Facultad De Ingenieria, Jan 17, 2014
Revista De Ingenieria, May 1, 2005
Momento Revista De Fisica, Dec 19, 2013
Revista De Ingenieria, May 1, 2005
Revista Facultad De Ingenieria Universidad De Antioquia, 2009
Revista De Ingenieria, May 1, 2007
Revista Colombiana De Materiales, May 19, 2014
Http Dx Doi Org 10 1080 10807039 2012 740653, Feb 6, 2014
ABSTRACT The database analysis allows the return of experience needed to support decision-making ... more ABSTRACT The database analysis allows the return of experience needed to support decision-making processes in risk management. A Colombian toxicological database (TED) developed and maintained by the Center of Safety Information and Chemical Products (CISPROQUIM by its Spanish abbreviation in) is analyzed here using a demographic clustering technique. Data-quality processes were performed on the raw data (more than 170 variables) and as a result the database was reduced to 20 meaningful variables. The variables characterized by values with categories were selected for clustering analysis: gender, age, type of emergency, emergency location, means of poisoning, product use, and physical state of the toxic substance. Clustering analysis showed that there are three profiles that are prevalent in the TED database: Young Adult Suicidal Woman, Unsupervised Child, and Man at Work. These profiles could not be identified using traditional statistical analyses performed on the data collected by CISPROQUIM or defined a priori from the categorical variables. The identification of vulnerable populations and the cause of the toxicological events are critical in order to develop national prevention programs and policies. The analysis described provided a methodology for a critical analysis of toxicological databases that can be applied to other databases such as security databases.
Revista De Ingenieria, May 1, 2007