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Papers by Aleksander Ryczkowski
Current Problems of Psychiatry
Introduction: Insomnia and obstructive sleep apnea are among the most common sleep-wake disorders... more Introduction: Insomnia and obstructive sleep apnea are among the most common sleep-wake disorders. A relatively new category of disorders, studied more thoroughly for only a few years, is the occurrence of symptoms of both obstructive sleep apnea and insomnia in one patient and treating it as a different disease entity. This phenomenon is increasingly referred to as COMISA (Co-morbid insomnia and sleep apnea). The aim of this paper is to: 1) draw attention to this interesting issue, 2) show treatment differences of COMISA from isolated insomnia or obstructive sleep apnea and to help choose better therapy by general practitioners, pulmonologists, and psychiatrists for these patients. Materials and methods: The literature review was based on a search of articles in Medline, PubMed, and Google Scholar from 2012 to 2023 using the keywords: obstructive sleep apnea; insomnia; cognitive behavioral therapy for insomnia; continuous positive airway pressure; COMISA. The analysis included orig...
After the application of oncological treatment, it is important to implement physiotherapy, the b... more After the application of oncological treatment, it is important to implement physiotherapy, the basic component of which is kinesitherapy. It is not always possible to implement the rehabilitation procedure early enough, so you should take into account the time spent in bed before starting the exercise and assess the physical performance. Research shows that the best benefits are achieved by activity undertaken 5 days a week, lasting a minimum of 1088
Methanol is a toxic alcohol that can imitate ethanol in smell and taste. It has many household an... more Methanol is a toxic alcohol that can imitate ethanol in smell and taste. It has many household and industrial applications but can also be present in informally-produced alcoholic beverages. Methanol poisoning feature with high mortality and may be seen due to its intentional or unintentional ingestion. Methanol does not have significant intrinsic activity but its metabolites, especially format leads to severe metabolic acidosis, visual disturbances and neurological deficit. Diagnosis is mainly based upon the typical clinical course, metabolic acidosis with high osmolar gap and detection of methanol in plasma or urine. Recent guidelines recommend therapy using the competitive alcohol dehydrogenase inhibitors-fomepizole or ethanol. In cases of severe poisoning hemodialysis should be considered. We present a case of a 39-year-old male who was considered to Emergency Department due to 997 consumed high amount of windshield washer fluid containing methanol. Intoxicated patient was unstable with respiratory insufficiency and consciousness impairment. Despite of implemented treatment-hemodialysis, ethanol infusion and active respiratory therapy-patient died on seventh day after admission to a hospital. Methanol poisonings feature with high mortality even when the best healthcare is provided. It depends mainly on a dose of ingested alcohol and delay in admission to a hospital.
Current Problems of Psychiatry, 2020
Introduction: Manganese has a role in the membrane transport systems, synthesis of protein, vitam... more Introduction: Manganese has a role in the membrane transport systems, synthesis of protein, vitamin C, and vitamins B, catalysis of hematopoiesis, regulation of the endocrine, immune system, blood sugar, reproduction, digestion, and blood coagulation. Furthermore, the level of manganese concentrations in human body appears to affect the occurrence of schizophrenia. The aim of this study was to search for relationships between the manganese level and the onset of schizophrenia. Material and methods: A descriptive review was performed based on a literature search on Medline and Google scholar from 2003 to 2020, using keywords: schizophrenia, manganese, Mn. The included studies were meta-analyses, case-control studies, and cohort studies that examined differences in manganese concentrations in patients with schizophrenia and healthy controls. Result: Eight studies were selected for the review, with one reporting elevated levels of manganese, two showing no significant differences, and ...
Current Problems of Psychiatry, 2021
Introduction: Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. ... more Introduction: Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. Its prevalence tends to increase worldwide. Untreated sleep apnea is associated with a higher risk of metabolic diseases, cardiovascular diseases, stroke, road accidents, and death, but also it is suggested that it increases the risk of mental disorders. Method: The literature review was based on a search of articles on Medline, Pubmed, and Google Scholar from 2003 to 2021 using the keywords: obstructive sleep apnea; mental disorders; cognitive functions; affective disorders; depression; bipolar disorder; schizophrenia; psychotic disorders. The analysis included original studies, meta-analysis, and review articles. Discussion: The result obtained from researches published so far does not allow for drawing unequivocal conclusions. There is a lot of bias present in study protocols and inclusion/exclusion criteria. Nonetheless, it seems that some disorders have a better proven correlation w...
Current Problems of Psychiatry, 2021
Summary Introduction: There is an ongoing debate as to whether the use of selective serotonin reu... more Summary Introduction: There is an ongoing debate as to whether the use of selective serotonin reuptake inhibitors (SSRIs) by pregnant women increases the risk of developing autism spectrum disorders (ASD) in the offspring. Aim: The aim of the study was to 1) present, based on a case report, the potential factors that may affect the development of ASD in a child, 2) review the literature on the risk of ASD in the case of using SSRIs by a pregnant woman. Case report: The case report concerns a child of a 33-year-old patient, previously treated for an episode of depression at the age of 23. At the beginning of the 15th week of planned pregnancy, when she was 28 years old, sleep disturbances were observed. Over the next few weeks, she gradually developed a full-blown depressive syndrome which required the use of sertraline. The child was born through a natural delivery, a healthy boy, who was diagnosed with ASD at the age of 2.5 years, which was the trigger for the development of the th...
European Journal of Clinical and Experimental Medicine, 2018
Introduction. Hyponatremia is a frequently observed electrolyte disorder among patients with canc... more Introduction. Hyponatremia is a frequently observed electrolyte disorder among patients with cancer. In 1957, Schwartz et al. reported the first case of a patient with hyponatremia due to SIADH, secondary to lung cancer. From that moment on, there has been data published that indicates patients with SIADH are less responsive to chemotherapy, have greater predisposition to central nervous system metastases and are often characterized by an advanced stage of cancer during time of diagnosis. Hyponatremia has many possible causes, and the differential diagnosis can pose a challenge. Aim. The aim of the study was to consider the occurrence of secondary hyponatremia in the course of cancer and the significance of this disorder in the prognosis of the disease. Methods. An analysis of the clinical history of the patient and a review of available literature. Results. A 66-year old patient with hyponatremia was admitted to the Department of Endocrinology, and lung cancer was determined as the cause of the aforementioned electrolyte disorder. Conclusion. SIADH secondary to cancers should be included in a differential diagnosis of every case of hyponatremia of undetermined etiology.
Current Problems of Psychiatry
Introduction: SARS-CoV-2 infection might be presented in many various specific and non-specific m... more Introduction: SARS-CoV-2 infection might be presented in many various specific and non-specific manifest and symptoms from different systems. Also, the psychotic symptoms are documented but the explanation for their pathophysiology remains debatable and a complex matter. The main objective of this paper is to present cases of patients without a history of psychiatric disorders who developed the first episode of psychosis during the SARS-CoV-2 infection. Material and methods: Two cases of not-related patients with no previous psychiatric history developed psychotic episodes during COVID-19 infection. In both cases chronologically first they experienced symptoms of infection, secondly, delusions and psychomotor agitation that required psychiatric hospitalization. Full remission was observed after antipsychotic treatment in both cases. Results: Even though the pathophysiology of the post-COVID-19 psychiatric symptoms remains unclear, some reports that indicate associations between the ...
Current Problems of Psychiatry
Introduction: Insomnia and obstructive sleep apnea are among the most common sleep-wake disorders... more Introduction: Insomnia and obstructive sleep apnea are among the most common sleep-wake disorders. A relatively new category of disorders, studied more thoroughly for only a few years, is the occurrence of symptoms of both obstructive sleep apnea and insomnia in one patient and treating it as a different disease entity. This phenomenon is increasingly referred to as COMISA (Co-morbid insomnia and sleep apnea). The aim of this paper is to: 1) draw attention to this interesting issue, 2) show treatment differences of COMISA from isolated insomnia or obstructive sleep apnea and to help choose better therapy by general practitioners, pulmonologists, and psychiatrists for these patients. Materials and methods: The literature review was based on a search of articles in Medline, PubMed, and Google Scholar from 2012 to 2023 using the keywords: obstructive sleep apnea; insomnia; cognitive behavioral therapy for insomnia; continuous positive airway pressure; COMISA. The analysis included orig...
After the application of oncological treatment, it is important to implement physiotherapy, the b... more After the application of oncological treatment, it is important to implement physiotherapy, the basic component of which is kinesitherapy. It is not always possible to implement the rehabilitation procedure early enough, so you should take into account the time spent in bed before starting the exercise and assess the physical performance. Research shows that the best benefits are achieved by activity undertaken 5 days a week, lasting a minimum of 1088
Methanol is a toxic alcohol that can imitate ethanol in smell and taste. It has many household an... more Methanol is a toxic alcohol that can imitate ethanol in smell and taste. It has many household and industrial applications but can also be present in informally-produced alcoholic beverages. Methanol poisoning feature with high mortality and may be seen due to its intentional or unintentional ingestion. Methanol does not have significant intrinsic activity but its metabolites, especially format leads to severe metabolic acidosis, visual disturbances and neurological deficit. Diagnosis is mainly based upon the typical clinical course, metabolic acidosis with high osmolar gap and detection of methanol in plasma or urine. Recent guidelines recommend therapy using the competitive alcohol dehydrogenase inhibitors-fomepizole or ethanol. In cases of severe poisoning hemodialysis should be considered. We present a case of a 39-year-old male who was considered to Emergency Department due to 997 consumed high amount of windshield washer fluid containing methanol. Intoxicated patient was unstable with respiratory insufficiency and consciousness impairment. Despite of implemented treatment-hemodialysis, ethanol infusion and active respiratory therapy-patient died on seventh day after admission to a hospital. Methanol poisonings feature with high mortality even when the best healthcare is provided. It depends mainly on a dose of ingested alcohol and delay in admission to a hospital.
Current Problems of Psychiatry, 2020
Introduction: Manganese has a role in the membrane transport systems, synthesis of protein, vitam... more Introduction: Manganese has a role in the membrane transport systems, synthesis of protein, vitamin C, and vitamins B, catalysis of hematopoiesis, regulation of the endocrine, immune system, blood sugar, reproduction, digestion, and blood coagulation. Furthermore, the level of manganese concentrations in human body appears to affect the occurrence of schizophrenia. The aim of this study was to search for relationships between the manganese level and the onset of schizophrenia. Material and methods: A descriptive review was performed based on a literature search on Medline and Google scholar from 2003 to 2020, using keywords: schizophrenia, manganese, Mn. The included studies were meta-analyses, case-control studies, and cohort studies that examined differences in manganese concentrations in patients with schizophrenia and healthy controls. Result: Eight studies were selected for the review, with one reporting elevated levels of manganese, two showing no significant differences, and ...
Current Problems of Psychiatry, 2021
Introduction: Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. ... more Introduction: Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. Its prevalence tends to increase worldwide. Untreated sleep apnea is associated with a higher risk of metabolic diseases, cardiovascular diseases, stroke, road accidents, and death, but also it is suggested that it increases the risk of mental disorders. Method: The literature review was based on a search of articles on Medline, Pubmed, and Google Scholar from 2003 to 2021 using the keywords: obstructive sleep apnea; mental disorders; cognitive functions; affective disorders; depression; bipolar disorder; schizophrenia; psychotic disorders. The analysis included original studies, meta-analysis, and review articles. Discussion: The result obtained from researches published so far does not allow for drawing unequivocal conclusions. There is a lot of bias present in study protocols and inclusion/exclusion criteria. Nonetheless, it seems that some disorders have a better proven correlation w...
Current Problems of Psychiatry, 2021
Summary Introduction: There is an ongoing debate as to whether the use of selective serotonin reu... more Summary Introduction: There is an ongoing debate as to whether the use of selective serotonin reuptake inhibitors (SSRIs) by pregnant women increases the risk of developing autism spectrum disorders (ASD) in the offspring. Aim: The aim of the study was to 1) present, based on a case report, the potential factors that may affect the development of ASD in a child, 2) review the literature on the risk of ASD in the case of using SSRIs by a pregnant woman. Case report: The case report concerns a child of a 33-year-old patient, previously treated for an episode of depression at the age of 23. At the beginning of the 15th week of planned pregnancy, when she was 28 years old, sleep disturbances were observed. Over the next few weeks, she gradually developed a full-blown depressive syndrome which required the use of sertraline. The child was born through a natural delivery, a healthy boy, who was diagnosed with ASD at the age of 2.5 years, which was the trigger for the development of the th...
European Journal of Clinical and Experimental Medicine, 2018
Introduction. Hyponatremia is a frequently observed electrolyte disorder among patients with canc... more Introduction. Hyponatremia is a frequently observed electrolyte disorder among patients with cancer. In 1957, Schwartz et al. reported the first case of a patient with hyponatremia due to SIADH, secondary to lung cancer. From that moment on, there has been data published that indicates patients with SIADH are less responsive to chemotherapy, have greater predisposition to central nervous system metastases and are often characterized by an advanced stage of cancer during time of diagnosis. Hyponatremia has many possible causes, and the differential diagnosis can pose a challenge. Aim. The aim of the study was to consider the occurrence of secondary hyponatremia in the course of cancer and the significance of this disorder in the prognosis of the disease. Methods. An analysis of the clinical history of the patient and a review of available literature. Results. A 66-year old patient with hyponatremia was admitted to the Department of Endocrinology, and lung cancer was determined as the cause of the aforementioned electrolyte disorder. Conclusion. SIADH secondary to cancers should be included in a differential diagnosis of every case of hyponatremia of undetermined etiology.
Current Problems of Psychiatry
Introduction: SARS-CoV-2 infection might be presented in many various specific and non-specific m... more Introduction: SARS-CoV-2 infection might be presented in many various specific and non-specific manifest and symptoms from different systems. Also, the psychotic symptoms are documented but the explanation for their pathophysiology remains debatable and a complex matter. The main objective of this paper is to present cases of patients without a history of psychiatric disorders who developed the first episode of psychosis during the SARS-CoV-2 infection. Material and methods: Two cases of not-related patients with no previous psychiatric history developed psychotic episodes during COVID-19 infection. In both cases chronologically first they experienced symptoms of infection, secondly, delusions and psychomotor agitation that required psychiatric hospitalization. Full remission was observed after antipsychotic treatment in both cases. Results: Even though the pathophysiology of the post-COVID-19 psychiatric symptoms remains unclear, some reports that indicate associations between the ...