Ana Dias - Academia.edu (original) (raw)
Papers by Ana Dias
Journal of Cleaner Production, 2003
In this paper, the Life Cycle Assessment (LCA) methodology is applied to Portuguese printing and ... more In this paper, the Life Cycle Assessment (LCA) methodology is applied to Portuguese printing and writing paper in order to compare the environmental impact of the use of two kinds of fuels (heavy fuel oil and natural gas) in the pulp and paper production processes. The results of inventory analysis and impact assessment show that the pulp and paper production processes play an important role in almost all of the analysed parameters, which do not always result in an important contribution to the corresponding impact categories. The substitution of heavy fuel oil by natural gas in the pulp and paper production processes seems to be environmentally positive.
Journal of Cleaner Production, 2003
In this paper, the Life Cycle Assessment (LCA) methodology is applied to Portuguese printing and ... more In this paper, the Life Cycle Assessment (LCA) methodology is applied to Portuguese printing and writing paper in order to compare the environmental impact of the use of two kinds of fuels (heavy fuel oil and natural gas) in the pulp and paper production processes. The results of inventory analysis and impact assessment show that the pulp and paper production processes play an important role in almost all of the analysed parameters, which do not always result in an important contribution to the corresponding impact categories. The substitution of heavy fuel oil by natural gas in the pulp and paper production processes seems to be environmentally positive.
. O trabalho tratasse a seguir apresentara uma definição dos conceitos básicos da contabilidade, ... more . O trabalho tratasse a seguir apresentara uma definição dos conceitos básicos da contabilidade, ativo, passivo, goodwill, receitas, despesas, ganhos e perdas, sua importância e como essas informações são geradas e auxiliam no controle dos serviços contábeis. Dentro deste trabalho faremos uma analise da teoria aplicada. Sua mensuração e relevância.
Journal of Hazardous Materials, 2005
In this work, it is intended to study the effect of adsorbent concentration on the adsorption of ... more In this work, it is intended to study the effect of adsorbent concentration on the adsorption of phenol by hexadecyl trimethyl ammoniumbentonite. The experiments were conducted in two groups. The adsorption of hexadecyl trimethyl ammonium bromide (HDTMA) on bentonite was studied in the first group of experiments. It was observed that the all HDTMA was adsorbed by the bentonite, even when the amount used exceeded 100% of cation exchange capacity (CEC). After the modification of bentonite by using HDTMA in an amount equivalent to 100% of CEC, the adsorption experiments were performed at five different adsorbent concentrations ranging from 2 to 10 g/L. A type V isotherm and a non-linear increase in percent removal with adsorbent concentration were observed. The observation of the non-linear relation between the percent removal and adsorbent concentration was attributed to the effect of intra particle interactions and it was represented by a second order polynomial. Several adsorption isotherm equations were applied to the experimental data. Although, the Freundlich equation fitted fairly well, it failed to represent the plateau and the second region that appeared in the isotherm. Therefore, an equation giving the equilibrium concentration as a function of initial and adsorbent concentrations was suggested.
Epilepsia, 2007
Summary: Purpose: SCN1A is the most clinically relevant epilepsy gene, most mutations lead to sev... more Summary: Purpose: SCN1A is the most clinically relevant epilepsy gene, most mutations lead to severe myoclonic epilepsy of infancy (SMEI) and generalized epilepsy with febrile seizures plus (GEFS+). We studied 132 patients with epilepsy syndromes with seizures precipitated by fever, and performed phenotype–genotype correlations with SCN1A alterations.Methods: We included patients with SMEI including borderline SMEI (SMEB), GEFS+, febrile seizures (FS), or other seizure types precipitated by fever. We performed a clinical and genetic study focusing on SCN1A, using dHPLC, gene sequencing, and MLPA to detect genomic deletions/duplications on SMEI/SMEB patients.Results: We classified patients as: SMEI/SMEB = 55; GEFS+= 26; and other phenotypes = 51. SCN1A analysis by dHPLC/sequencing revealed 40 mutations in 37 SMEI/SMEB (67%) and 3 GEFS+ (11.5%) probands. MLPA showed genomic deletions in 2 of 18 SMEI/SMEB. Most mutations were de novo (82%). SMEB patients carrying mutations (8) were more likely to have missense mutations (62.5%), conversely SMEI patients (31) had more truncating, splice site or genomic alterations (64.5%). SMEI/SMEB with truncating, splice site or genomic alterations had a significantly earlier age of onset of FS compared to those with missense mutations and without mutations (p = 0.00007, ANOVA test). None of the remaining patients with seizures precipitated by fever carried SCN1A mutations.Conclusion: We obtained a frequency of 71%SCN1A abnormalities in SMEI/SMEB and of 11.5% in GEFS+ probands. MLPA complements DNA sequencing of SCN1A increasing the mutation detection rate. SMEI/SMEB with truncating, splice site or genomic alterations had a significantly earlier age of onset of FS. This study confirms the high sensitivity of SCN1A for SMEI/SMEB phenotypes.
. O trabalho tratasse a seguir apresentara uma definição dos conceitos básicos da contabilidade, ... more . O trabalho tratasse a seguir apresentara uma definição dos conceitos básicos da contabilidade, ativo, passivo, goodwill, receitas, despesas, ganhos e perdas, sua importância e como essas informações são geradas e auxiliam no controle dos serviços contábeis. Dentro deste trabalho faremos uma analise da teoria aplicada. Sua mensuração e relevância.
Journal of Cleaner Production, 2003
In this paper, the Life Cycle Assessment (LCA) methodology is applied to Portuguese printing and ... more In this paper, the Life Cycle Assessment (LCA) methodology is applied to Portuguese printing and writing paper in order to compare the environmental impact of the use of two kinds of fuels (heavy fuel oil and natural gas) in the pulp and paper production processes. The results of inventory analysis and impact assessment show that the pulp and paper production processes play an important role in almost all of the analysed parameters, which do not always result in an important contribution to the corresponding impact categories. The substitution of heavy fuel oil by natural gas in the pulp and paper production processes seems to be environmentally positive.
Journal of Cleaner Production, 2003
In this paper, the Life Cycle Assessment (LCA) methodology is applied to Portuguese printing and ... more In this paper, the Life Cycle Assessment (LCA) methodology is applied to Portuguese printing and writing paper in order to compare the environmental impact of the use of two kinds of fuels (heavy fuel oil and natural gas) in the pulp and paper production processes. The results of inventory analysis and impact assessment show that the pulp and paper production processes play an important role in almost all of the analysed parameters, which do not always result in an important contribution to the corresponding impact categories. The substitution of heavy fuel oil by natural gas in the pulp and paper production processes seems to be environmentally positive.
. O trabalho tratasse a seguir apresentara uma definição dos conceitos básicos da contabilidade, ... more . O trabalho tratasse a seguir apresentara uma definição dos conceitos básicos da contabilidade, ativo, passivo, goodwill, receitas, despesas, ganhos e perdas, sua importância e como essas informações são geradas e auxiliam no controle dos serviços contábeis. Dentro deste trabalho faremos uma analise da teoria aplicada. Sua mensuração e relevância.
Journal of Hazardous Materials, 2005
In this work, it is intended to study the effect of adsorbent concentration on the adsorption of ... more In this work, it is intended to study the effect of adsorbent concentration on the adsorption of phenol by hexadecyl trimethyl ammoniumbentonite. The experiments were conducted in two groups. The adsorption of hexadecyl trimethyl ammonium bromide (HDTMA) on bentonite was studied in the first group of experiments. It was observed that the all HDTMA was adsorbed by the bentonite, even when the amount used exceeded 100% of cation exchange capacity (CEC). After the modification of bentonite by using HDTMA in an amount equivalent to 100% of CEC, the adsorption experiments were performed at five different adsorbent concentrations ranging from 2 to 10 g/L. A type V isotherm and a non-linear increase in percent removal with adsorbent concentration were observed. The observation of the non-linear relation between the percent removal and adsorbent concentration was attributed to the effect of intra particle interactions and it was represented by a second order polynomial. Several adsorption isotherm equations were applied to the experimental data. Although, the Freundlich equation fitted fairly well, it failed to represent the plateau and the second region that appeared in the isotherm. Therefore, an equation giving the equilibrium concentration as a function of initial and adsorbent concentrations was suggested.
Epilepsia, 2007
Summary: Purpose: SCN1A is the most clinically relevant epilepsy gene, most mutations lead to sev... more Summary: Purpose: SCN1A is the most clinically relevant epilepsy gene, most mutations lead to severe myoclonic epilepsy of infancy (SMEI) and generalized epilepsy with febrile seizures plus (GEFS+). We studied 132 patients with epilepsy syndromes with seizures precipitated by fever, and performed phenotype–genotype correlations with SCN1A alterations.Methods: We included patients with SMEI including borderline SMEI (SMEB), GEFS+, febrile seizures (FS), or other seizure types precipitated by fever. We performed a clinical and genetic study focusing on SCN1A, using dHPLC, gene sequencing, and MLPA to detect genomic deletions/duplications on SMEI/SMEB patients.Results: We classified patients as: SMEI/SMEB = 55; GEFS+= 26; and other phenotypes = 51. SCN1A analysis by dHPLC/sequencing revealed 40 mutations in 37 SMEI/SMEB (67%) and 3 GEFS+ (11.5%) probands. MLPA showed genomic deletions in 2 of 18 SMEI/SMEB. Most mutations were de novo (82%). SMEB patients carrying mutations (8) were more likely to have missense mutations (62.5%), conversely SMEI patients (31) had more truncating, splice site or genomic alterations (64.5%). SMEI/SMEB with truncating, splice site or genomic alterations had a significantly earlier age of onset of FS compared to those with missense mutations and without mutations (p = 0.00007, ANOVA test). None of the remaining patients with seizures precipitated by fever carried SCN1A mutations.Conclusion: We obtained a frequency of 71%SCN1A abnormalities in SMEI/SMEB and of 11.5% in GEFS+ probands. MLPA complements DNA sequencing of SCN1A increasing the mutation detection rate. SMEI/SMEB with truncating, splice site or genomic alterations had a significantly earlier age of onset of FS. This study confirms the high sensitivity of SCN1A for SMEI/SMEB phenotypes.
. O trabalho tratasse a seguir apresentara uma definição dos conceitos básicos da contabilidade, ... more . O trabalho tratasse a seguir apresentara uma definição dos conceitos básicos da contabilidade, ativo, passivo, goodwill, receitas, despesas, ganhos e perdas, sua importância e como essas informações são geradas e auxiliam no controle dos serviços contábeis. Dentro deste trabalho faremos uma analise da teoria aplicada. Sua mensuração e relevância.