Andy Whyte - Academia.edu (original) (raw)

Papers by Andy Whyte

Research paper thumbnail of The radiology of acquired unilateral proptosis

Poster: "ECR 2010 / C-1778 / The radiology of acquired unilateral proptosis" by: "... more Poster: "ECR 2010 / C-1778 / The radiology of acquired unilateral proptosis" by: "E. Kashef1, D. Gibson2, A. Whyte3; 1London/UK, 2Portsmouth/UK, 3Perth/AU"

Research paper thumbnail of A diaphragmatic nick

British Journal of Radiology, Apr 1, 1990

A 27-year-old man was admitted with acute onset of severe, constant epigastric pain and vomiting ... more A 27-year-old man was admitted with acute onset of severe, constant epigastric pain and vomiting associated with lifting at work. There were no other symptoms. Four years previously he had attended the Casualty Department with a knife wound to the left chest which had been sutured. Examination revealed only generalized abdominal tenderness. Haematological and biochemical investigations showed a mildly elevated white cell count (16.1 × 109/L). Abdominal radiographs were unremarkable. Forty-eight hours after admission he deteriorated rapidly with increasing abdominal pain, hypotension and tachycardia.

Research paper thumbnail of External pneumatocoele of the mastoid system

Anz Journal of Surgery, Feb 1, 2003

Research paper thumbnail of Epithelioid sarcoma of the forearm

Journal of Medical Imaging and Radiation Oncology, Aug 1, 1996

A case of epithelioid sarcoma of the forearm is described. The radiological and pathological feat... more A case of epithelioid sarcoma of the forearm is described. The radiological and pathological features, natural history of the tumour and its treatment are reviewed.

Research paper thumbnail of Endolymphatic Sac Tumor

Otology & Neurotology, Jul 1, 2005

Endolymphatic sac tumors are rare, aggressive vascular tumors of papillary architecture that orig... more Endolymphatic sac tumors are rare, aggressive vascular tumors of papillary architecture that originate in the sac and have an association with von Hippel-Lindau disease (1). Endolymphatic sac tumors are typically retrolabyrinthine in location, centered in the fovea of the endolymphatic sac along the posterior wall of the temporal bone. They have a significant propensity to spread in a number of ways (2). Mukherji et al. (3) showed a correlation between middle ear spread and the size of tumor. Because of the anatomic complexity of the temporal bone, it is important to investigate these tumors radiologically in three dimensions before outlining a management plan (4). Computed tomography (CT) and magnetic resonance imaging (MRI) studies (Figs. 1–3) are required for full assessment of endolymphatic sac tumors. Both MRI and CT studies demonstrate the characteristic retrolabyrinthine modalities and locations of tumor, as well as specific findings for each imaging method. CT examination optimally demonstrates the ill-defined bone destruction of the posterior wall of the temporal bone, central spiculated calcification within the tumor matrix in the majority of cases, and usually a thin rim of calcification along the posterior wall of the tumor. MRI examination demonstrates high-signal foci secondary to hemorrhage within or at the margin of endolymphatic sac tumors on a T1-weighted, unenhanced sequence in 80% of cases. Flow voids (focal low-signal punctate or serpiginous foci) are seen in tumors greater than 2 cm in diameter. All tumors show heterogeneous enhancement

Research paper thumbnail of Frontal recess air cells: Spectrum of CT appearances

Journal of Medical Imaging and Radiation Oncology, Feb 6, 2003

The CT appearances of frontal recess air cells is reviewed.

Research paper thumbnail of Bronchogenic carcinoma metastasizing to the orbit

Journal of Maxillofacial Surgery, 1978

A case of an orbital metastasis from a bronchogenic neoplasm is described. The initial clinical p... more A case of an orbital metastasis from a bronchogenic neoplasm is described. The initial clinical presentation was of unilateral facial pain and paraesthesia shortly followed by increasing left-sided external ophthalmoplegia and proptosis and the development of a slight swelling of the left temporal fossa. The diagnosis was established by a biopsy of the temporal mass. The patient died two months after the diagnosis was established. The significance of facial pain and paraesthesia and the literature pertaining to orbital cellulitis and orbital metastases is discussed.

Research paper thumbnail of Pocket Radiologist: Head and Neck - Top 100 Diagnoses

Australasian Radiology, 2003

Retour page d'accueil Chercher, sur, Tous les supports. Retour page d'accueil, Plus de ... more Retour page d'accueil Chercher, sur, Tous les supports. Retour page d'accueil, Plus de 1.629.000 de titres à notre catalogue ! Notice. ...

Research paper thumbnail of Case report: Mediastinal lipoblastoma of infancy

Clinical Radiology, 1990

We report the case of a rapidly expanding mediastinal and chest wall lipoblastoma in an 11-month ... more We report the case of a rapidly expanding mediastinal and chest wall lipoblastoma in an 11-month old infant. Clinical presentation was respiratory distress and chest radiographs revealed a large soft tissue mass in the anterior mediastinum without specific features. CT scanning demonstrated a mass of principally fat attenuation, with enhancing hyperdense soft tissue whorls, which had a compressive effect on normal intrathoracic structures. At surgery the tumour was removed without complication and histology demonstrated an encapsulated, well differentiated lipoblastoma.

Research paper thumbnail of The hypoglossal canal: normal MR enhancement pattern

AJNR. American journal of neuroradiology, 1995

To review the anatomy of the hypoglossal canal and present the normal precontrast and postcontras... more To review the anatomy of the hypoglossal canal and present the normal precontrast and postcontrast MR appearance of axial posterior fossa images. Thirty-one axial MR examinations of the normal posterior fossa were retrospectively reviewed. The hypoglossal canals are well seen on 3-mm-thick axial MR images of the posterior fossa (28 [90%] of 31 patients). Symmetric intense intracanalicular enhancement after intravenous administration of gadopentetate dimeglumine is routine, typically with minor anterior extension into the nasopharyngeal region (28 [100%] of 28). A linear filling defect traversing the enhanced canal often is seen (21 [75%] of 28) and may represent hypoglossal nerve rootlets. Circumferential enhancement of the meninges at the level of the foramen magnum was a common finding (19 [64%] of 28). Enhancement within the hypoglossal canal with anterior extension beneath the skull base is a normal finding. This pattern is characteristic enough on MR imaging to aid interpretati...

Research paper thumbnail of Imaging of orofacial pain

Journal of Oral Pathology & Medicine, 2020

BACKGROUND Orofacial pain is a common complaint, with an estimated 75% of cases caused by dental ... more BACKGROUND Orofacial pain is a common complaint, with an estimated 75% of cases caused by dental disease, specifically a diseased pulp. A small percentage of orofacial pain cases will require specialist referral most commonly to oral medicine specialists or oral and maxillofacial surgeons from a dental perspective, or otolaryngologists or neurologists from a medical perspective. IMAGING MODALITIES Following a thorough history and clinical examination, imaging is often required to narrow the differential diagnosis or answer a specific query related to the final diagnosis. A range of imaging modalities can be used to evaluate orofacial pain including dental panoramic tomography (DPT), intraoral radiographs, Cone Beam Computed Tomography (CBCT), Multidetector Computed Tomography (MDCT), Ultrasonography (US), Magnetic Resonance Imaging (MRI), and Nuclear Medicine. IMAGING PROTOCOLS This paper provides a guideline outlining imaging protocols for categories of facial pain divided into: (i) unilateral odontalgia; (ii) unilateral facial pain; (iii) combined unilateral odontalgia and facial pain; (iv) trigeminal neuralgia; (v) trigeminal neuropathic pain with or without other sensory, autonomic or motor features; (vi) temporomandibular joint disorders and associated pain; (vii) referred pain and (viii) non-specific orofacial pain. CONCLUSION Imaging for orofacial pain should be tailored to answer a specific query related to the aetiology of the reported pain. This should result in a specific diagnosis or narrowing of the differential diagnosis as possible causes of orofacial pain are eliminated. Choosing the correct imaging modality and protocol based on the pain category is important for efficient and effective pain diagnosis and management.

Research paper thumbnail of Imaging of Trigeminal Neuralgia and Other Facial Pain

Neuroimaging Clinics of North America, 2021

We review and illustrate the radiology of facial pain, emphasizing trigeminal neuralgia, relevant... more We review and illustrate the radiology of facial pain, emphasizing trigeminal neuralgia, relevant anatomy, current classification, concepts about etiology, and the role of imaging and its influence on the choice of treatment. We discuss glossopharyngeal neuralgia, other neuropathic causes of facial pain, postinflammatory and neoplastic causes, and nociceptive (end-organ) causes of facial pain, as well as referred otalgia. Other conditions that may present with facial pain, including trigeminal autonomic cephalgias and giant cell arteritis, are reviewed briefly. We discuss the elements of a comprehensive MR imaging protocol to enable detection of these diverse causes of facial pain.

Research paper thumbnail of Imaging of temporomandibular disorder and its mimics

Journal of Medical Imaging and Radiation Oncology, 2020

Tony Conigliaro, London-based mixologist and bar owner, talks to Flavour about the scientific met... more Tony Conigliaro, London-based mixologist and bar owner, talks to Flavour about the scientific methods and equipment he has brought into cocktail making. Opinion Tony Conigliaro is a London-based mixologist and owner of cocktail bars 69 Colebrooke Row and The Zetter Town House, both in London, UK. He also runs the Drink Factory, a bespoke lab that focuses on alcohol-development and research into liquid flavour, drinks and cocktails. Widely acknowledged as one of the UK's pioneering drinks creators, he won the award for International Bartender of the Year 2009, as well as the Observer Food Monthly award for Bar of the Year in 2010. His new book, Drinks, is released later this year. In a Q & A with Flavour, Tony Conigliaro talks about the scientific methods and equipment he has brought into cocktail making and some of the new drinks he has created.

Research paper thumbnail of Adult obstructive sleep apnoea: Pathogenesis, importance, diagnosis and imaging

Journal of Medical Imaging and Radiation Oncology, 2019

Obstructive sleep apnoea (OSA) is a serious worldwide health problem. Moderate-to-severe OSA has ... more Obstructive sleep apnoea (OSA) is a serious worldwide health problem. Moderate-to-severe OSA has been found in up to 50% of men and 25% of women in the middle-aged population. It results in a fourfold increase in all causes of mortality. The prevalence of OSA is underestimated, partly due to absence of symptoms but also lack of knowledge amongst the population at large as well as sectors of the medical profession. Imaging, performed predominantly by clinicians and research scientists, has been integral to evaluating the anatomical basis of OSA. Increased nasal resistance and a narrowed and elongated oropharynx lead to increased collapsibility of the upper airway, predisposing to airway collapse and apnoea during sleep when there is reduction in tone of the pharyngeal dilator muscles. Unfortunately, a significantly narrowed upper airway is usually ignored by radiologists: it is not part of their reporting 'check-list'. The imaging findings in the upper airway that are strongly associated with OSA and its sequelae in various organ systems are discussed. Imaging can strongly suggest OSA; the diagnosis requires a polysomnogram for confirmation. Treatment of moderate-to-severe disease is primarily with positive airway pressure applied by a nasal or oral mask which splints the upper airway. Although highly effective, compliance is limited and other treatment modalities are increasingly being utilized.

Research paper thumbnail of Imaging of adult obstructive sleep apnoea

European Journal of Radiology, 2018

Obstructive sleep apnoea (OSA) is characterised by recurrent upper airway collapse during sleep r... more Obstructive sleep apnoea (OSA) is characterised by recurrent upper airway collapse during sleep resulting in chronic and repetitive hypoxia, hypercapnia, subsequent arousal and fragmented sleep. Symptoms are insidious and diagnosis is usually delayed. Moderate to severe OSA has serious health implications with significant increase in all causes of mortality in patients with the condition as compared with unaffected individuals. The prevalence of OSA in the 30-70 year age group is estimated at 27% of males and 11% of females and it increases with age. 80% of affected individuals are obese and as obesity rates rise, so has the prevalence of OSA. An overnight polysomnogram (PSG) is required for a definitive diagnosis of OSA. Imaging has played a fundamental role in the evaluation of the anatomical factors associated with recurrent upper airway collapse and the pathogenesis of OSA. The upper airway is frequently imaged by radiologists, providing an opportunity to detect features that are strongly associated with unsuspected OSA and to raise the possibility of this diagnosis. The gold standard of treatment is continuous positive airway pressure (CPAP) which acts as a pneumatic splint for the upper airway. However, efficacy is frequently limited by poor tolerance; clinicians and patients are increasingly opting for one of a range of surgical procedures. Dedicated imaging protocols can be performed for evaluation of the upper airway to aid surgical planning.

Research paper thumbnail of Endolymphatic Sac Tumor

Otology & Neurotology, 2005

Endolymphatic sac tumors are rare, aggressive vascular tumors of papillary architecture that orig... more Endolymphatic sac tumors are rare, aggressive vascular tumors of papillary architecture that originate in the sac and have an association with von Hippel-Lindau disease (1). Endolymphatic sac tumors are typically retrolabyrinthine in location, centered in the fovea of the endolymphatic sac along the posterior wall of the temporal bone. They have a significant propensity to spread in a number of ways (2). Mukherji et al. (3) showed a correlation between middle ear spread and the size of tumor. Because of the anatomic complexity of the temporal bone, it is important to investigate these tumors radiologically in three dimensions before outlining a management plan (4). Computed tomography (CT) and magnetic resonance imaging (MRI) studies (Figs. 1–3) are required for full assessment of endolymphatic sac tumors. Both MRI and CT studies demonstrate the characteristic retrolabyrinthine modalities and locations of tumor, as well as specific findings for each imaging method. CT examination optimally demonstrates the ill-defined bone destruction of the posterior wall of the temporal bone, central spiculated calcification within the tumor matrix in the majority of cases, and usually a thin rim of calcification along the posterior wall of the tumor. MRI examination demonstrates high-signal foci secondary to hemorrhage within or at the margin of endolymphatic sac tumors on a T1-weighted, unenhanced sequence in 80% of cases. Flow voids (focal low-signal punctate or serpiginous foci) are seen in tumors greater than 2 cm in diameter. All tumors show heterogeneous enhancement

Research paper thumbnail of Rotation of the osseous spiral lamina from the hook region along the basal turn of the cochlea: results of a magnetic resonance image anatomical study using high-resolution DRIVE sequences

Surgical and Radiologic Anatomy, 2011

To define the rotational anatomy of the osseous spiral lamina (OSL) at the hook region and along ... more To define the rotational anatomy of the osseous spiral lamina (OSL) at the hook region and along the basal turn of the cochlea and to illustrate the potential utility of high-resolution MRI images to study inner ear ultrastructure. Retrospective review of high-resolution temporal bone MRI images in 20 consecutive adult patients referred for imaging unrelated to hearing loss. The main outcome measure utilised images in an oblique sagittal plane to measure the rotation of the OSL relative to the vertical axis in the hook region and along the basal turn of the cochlea. The right OSL is noted to rotate in a clockwise direction as one proceeds anteriorly; over the same distance, the left OSL rotates in an anti-clockwise direction. The average overall rotation for all subjects as measured over a distance of 1-7 mm from the posterior margin of the round window was 25.95°. Inter-subject variability was noted. Prominent rotation of the OSL was noted in the hook region, this being most pronounced in the proximity to the round window. This concept may have implications for cochleostomy site selection with implant surgery. The study highlights the feasibility of high-resolution MRI to be used to systematically study variations in intra-cochlear anatomy.

Research paper thumbnail of Computed tomography of the temporomandibular joint

Journal of Medical Imaging and Radiation Oncology, 2012

Computed tomography (CT) of the temporo-mandibular joint (TMJ) has only been occasionally reporte... more Computed tomography (CT) of the temporo-mandibular joint (TMJ) has only been occasionally reported. As CT techniques improve, more detailed information is available. Though conventional radiography of the TMJ can supply sufficient diagnostic detail, it may well be replaced by CT as a preliminary examination, as it is able to offer more information with less radiation and minimal patient discomfort.

Research paper thumbnail of Dental panoramic tomography: An approach for the general radiologist

Australasian Radiology, 2006

Dental panoramic tomography is commonly presented to radiologists with no dental training for int... more Dental panoramic tomography is commonly presented to radiologists with no dental training for interpretation. An overview of the technique, basic anatomy and nomenclature and common pathology is presented with examples to show the anatomy and nomenclature, the artefacts and common pathology.

Research paper thumbnail of Current concepts in maxillofacial imaging

European Journal of Radiology, 2008

A review of state-of-the-art maxillofacial imaging is presented. Current imaging techniques inclu... more A review of state-of-the-art maxillofacial imaging is presented. Current imaging techniques include intra-oral radiographs, dental panoramic tomography, multidetector helical computed tomography, cone-beam computed tomography (CBCT) and magnetic resonance imaging (MRI). The commonest conditions encountered in clinical radiological practice are reviewed, including maxillofacial deformities, complicated dental impactions, maxillofacial trauma, jaw lesions (cysts, neoplasms, fibro-osseous lesions (FOLs) and infections), and temporomandibular joint pathology. Pre-operative assessment for dental implant placement is also briefly reviewed.

Research paper thumbnail of The radiology of acquired unilateral proptosis

Poster: "ECR 2010 / C-1778 / The radiology of acquired unilateral proptosis" by: "... more Poster: "ECR 2010 / C-1778 / The radiology of acquired unilateral proptosis" by: "E. Kashef1, D. Gibson2, A. Whyte3; 1London/UK, 2Portsmouth/UK, 3Perth/AU"

Research paper thumbnail of A diaphragmatic nick

British Journal of Radiology, Apr 1, 1990

A 27-year-old man was admitted with acute onset of severe, constant epigastric pain and vomiting ... more A 27-year-old man was admitted with acute onset of severe, constant epigastric pain and vomiting associated with lifting at work. There were no other symptoms. Four years previously he had attended the Casualty Department with a knife wound to the left chest which had been sutured. Examination revealed only generalized abdominal tenderness. Haematological and biochemical investigations showed a mildly elevated white cell count (16.1 × 109/L). Abdominal radiographs were unremarkable. Forty-eight hours after admission he deteriorated rapidly with increasing abdominal pain, hypotension and tachycardia.

Research paper thumbnail of External pneumatocoele of the mastoid system

Anz Journal of Surgery, Feb 1, 2003

Research paper thumbnail of Epithelioid sarcoma of the forearm

Journal of Medical Imaging and Radiation Oncology, Aug 1, 1996

A case of epithelioid sarcoma of the forearm is described. The radiological and pathological feat... more A case of epithelioid sarcoma of the forearm is described. The radiological and pathological features, natural history of the tumour and its treatment are reviewed.

Research paper thumbnail of Endolymphatic Sac Tumor

Otology & Neurotology, Jul 1, 2005

Endolymphatic sac tumors are rare, aggressive vascular tumors of papillary architecture that orig... more Endolymphatic sac tumors are rare, aggressive vascular tumors of papillary architecture that originate in the sac and have an association with von Hippel-Lindau disease (1). Endolymphatic sac tumors are typically retrolabyrinthine in location, centered in the fovea of the endolymphatic sac along the posterior wall of the temporal bone. They have a significant propensity to spread in a number of ways (2). Mukherji et al. (3) showed a correlation between middle ear spread and the size of tumor. Because of the anatomic complexity of the temporal bone, it is important to investigate these tumors radiologically in three dimensions before outlining a management plan (4). Computed tomography (CT) and magnetic resonance imaging (MRI) studies (Figs. 1–3) are required for full assessment of endolymphatic sac tumors. Both MRI and CT studies demonstrate the characteristic retrolabyrinthine modalities and locations of tumor, as well as specific findings for each imaging method. CT examination optimally demonstrates the ill-defined bone destruction of the posterior wall of the temporal bone, central spiculated calcification within the tumor matrix in the majority of cases, and usually a thin rim of calcification along the posterior wall of the tumor. MRI examination demonstrates high-signal foci secondary to hemorrhage within or at the margin of endolymphatic sac tumors on a T1-weighted, unenhanced sequence in 80% of cases. Flow voids (focal low-signal punctate or serpiginous foci) are seen in tumors greater than 2 cm in diameter. All tumors show heterogeneous enhancement

Research paper thumbnail of Frontal recess air cells: Spectrum of CT appearances

Journal of Medical Imaging and Radiation Oncology, Feb 6, 2003

The CT appearances of frontal recess air cells is reviewed.

Research paper thumbnail of Bronchogenic carcinoma metastasizing to the orbit

Journal of Maxillofacial Surgery, 1978

A case of an orbital metastasis from a bronchogenic neoplasm is described. The initial clinical p... more A case of an orbital metastasis from a bronchogenic neoplasm is described. The initial clinical presentation was of unilateral facial pain and paraesthesia shortly followed by increasing left-sided external ophthalmoplegia and proptosis and the development of a slight swelling of the left temporal fossa. The diagnosis was established by a biopsy of the temporal mass. The patient died two months after the diagnosis was established. The significance of facial pain and paraesthesia and the literature pertaining to orbital cellulitis and orbital metastases is discussed.

Research paper thumbnail of Pocket Radiologist: Head and Neck - Top 100 Diagnoses

Australasian Radiology, 2003

Retour page d'accueil Chercher, sur, Tous les supports. Retour page d'accueil, Plus de ... more Retour page d'accueil Chercher, sur, Tous les supports. Retour page d'accueil, Plus de 1.629.000 de titres à notre catalogue ! Notice. ...

Research paper thumbnail of Case report: Mediastinal lipoblastoma of infancy

Clinical Radiology, 1990

We report the case of a rapidly expanding mediastinal and chest wall lipoblastoma in an 11-month ... more We report the case of a rapidly expanding mediastinal and chest wall lipoblastoma in an 11-month old infant. Clinical presentation was respiratory distress and chest radiographs revealed a large soft tissue mass in the anterior mediastinum without specific features. CT scanning demonstrated a mass of principally fat attenuation, with enhancing hyperdense soft tissue whorls, which had a compressive effect on normal intrathoracic structures. At surgery the tumour was removed without complication and histology demonstrated an encapsulated, well differentiated lipoblastoma.

Research paper thumbnail of The hypoglossal canal: normal MR enhancement pattern

AJNR. American journal of neuroradiology, 1995

To review the anatomy of the hypoglossal canal and present the normal precontrast and postcontras... more To review the anatomy of the hypoglossal canal and present the normal precontrast and postcontrast MR appearance of axial posterior fossa images. Thirty-one axial MR examinations of the normal posterior fossa were retrospectively reviewed. The hypoglossal canals are well seen on 3-mm-thick axial MR images of the posterior fossa (28 [90%] of 31 patients). Symmetric intense intracanalicular enhancement after intravenous administration of gadopentetate dimeglumine is routine, typically with minor anterior extension into the nasopharyngeal region (28 [100%] of 28). A linear filling defect traversing the enhanced canal often is seen (21 [75%] of 28) and may represent hypoglossal nerve rootlets. Circumferential enhancement of the meninges at the level of the foramen magnum was a common finding (19 [64%] of 28). Enhancement within the hypoglossal canal with anterior extension beneath the skull base is a normal finding. This pattern is characteristic enough on MR imaging to aid interpretati...

Research paper thumbnail of Imaging of orofacial pain

Journal of Oral Pathology & Medicine, 2020

BACKGROUND Orofacial pain is a common complaint, with an estimated 75% of cases caused by dental ... more BACKGROUND Orofacial pain is a common complaint, with an estimated 75% of cases caused by dental disease, specifically a diseased pulp. A small percentage of orofacial pain cases will require specialist referral most commonly to oral medicine specialists or oral and maxillofacial surgeons from a dental perspective, or otolaryngologists or neurologists from a medical perspective. IMAGING MODALITIES Following a thorough history and clinical examination, imaging is often required to narrow the differential diagnosis or answer a specific query related to the final diagnosis. A range of imaging modalities can be used to evaluate orofacial pain including dental panoramic tomography (DPT), intraoral radiographs, Cone Beam Computed Tomography (CBCT), Multidetector Computed Tomography (MDCT), Ultrasonography (US), Magnetic Resonance Imaging (MRI), and Nuclear Medicine. IMAGING PROTOCOLS This paper provides a guideline outlining imaging protocols for categories of facial pain divided into: (i) unilateral odontalgia; (ii) unilateral facial pain; (iii) combined unilateral odontalgia and facial pain; (iv) trigeminal neuralgia; (v) trigeminal neuropathic pain with or without other sensory, autonomic or motor features; (vi) temporomandibular joint disorders and associated pain; (vii) referred pain and (viii) non-specific orofacial pain. CONCLUSION Imaging for orofacial pain should be tailored to answer a specific query related to the aetiology of the reported pain. This should result in a specific diagnosis or narrowing of the differential diagnosis as possible causes of orofacial pain are eliminated. Choosing the correct imaging modality and protocol based on the pain category is important for efficient and effective pain diagnosis and management.

Research paper thumbnail of Imaging of Trigeminal Neuralgia and Other Facial Pain

Neuroimaging Clinics of North America, 2021

We review and illustrate the radiology of facial pain, emphasizing trigeminal neuralgia, relevant... more We review and illustrate the radiology of facial pain, emphasizing trigeminal neuralgia, relevant anatomy, current classification, concepts about etiology, and the role of imaging and its influence on the choice of treatment. We discuss glossopharyngeal neuralgia, other neuropathic causes of facial pain, postinflammatory and neoplastic causes, and nociceptive (end-organ) causes of facial pain, as well as referred otalgia. Other conditions that may present with facial pain, including trigeminal autonomic cephalgias and giant cell arteritis, are reviewed briefly. We discuss the elements of a comprehensive MR imaging protocol to enable detection of these diverse causes of facial pain.

Research paper thumbnail of Imaging of temporomandibular disorder and its mimics

Journal of Medical Imaging and Radiation Oncology, 2020

Tony Conigliaro, London-based mixologist and bar owner, talks to Flavour about the scientific met... more Tony Conigliaro, London-based mixologist and bar owner, talks to Flavour about the scientific methods and equipment he has brought into cocktail making. Opinion Tony Conigliaro is a London-based mixologist and owner of cocktail bars 69 Colebrooke Row and The Zetter Town House, both in London, UK. He also runs the Drink Factory, a bespoke lab that focuses on alcohol-development and research into liquid flavour, drinks and cocktails. Widely acknowledged as one of the UK's pioneering drinks creators, he won the award for International Bartender of the Year 2009, as well as the Observer Food Monthly award for Bar of the Year in 2010. His new book, Drinks, is released later this year. In a Q & A with Flavour, Tony Conigliaro talks about the scientific methods and equipment he has brought into cocktail making and some of the new drinks he has created.

Research paper thumbnail of Adult obstructive sleep apnoea: Pathogenesis, importance, diagnosis and imaging

Journal of Medical Imaging and Radiation Oncology, 2019

Obstructive sleep apnoea (OSA) is a serious worldwide health problem. Moderate-to-severe OSA has ... more Obstructive sleep apnoea (OSA) is a serious worldwide health problem. Moderate-to-severe OSA has been found in up to 50% of men and 25% of women in the middle-aged population. It results in a fourfold increase in all causes of mortality. The prevalence of OSA is underestimated, partly due to absence of symptoms but also lack of knowledge amongst the population at large as well as sectors of the medical profession. Imaging, performed predominantly by clinicians and research scientists, has been integral to evaluating the anatomical basis of OSA. Increased nasal resistance and a narrowed and elongated oropharynx lead to increased collapsibility of the upper airway, predisposing to airway collapse and apnoea during sleep when there is reduction in tone of the pharyngeal dilator muscles. Unfortunately, a significantly narrowed upper airway is usually ignored by radiologists: it is not part of their reporting 'check-list'. The imaging findings in the upper airway that are strongly associated with OSA and its sequelae in various organ systems are discussed. Imaging can strongly suggest OSA; the diagnosis requires a polysomnogram for confirmation. Treatment of moderate-to-severe disease is primarily with positive airway pressure applied by a nasal or oral mask which splints the upper airway. Although highly effective, compliance is limited and other treatment modalities are increasingly being utilized.

Research paper thumbnail of Imaging of adult obstructive sleep apnoea

European Journal of Radiology, 2018

Obstructive sleep apnoea (OSA) is characterised by recurrent upper airway collapse during sleep r... more Obstructive sleep apnoea (OSA) is characterised by recurrent upper airway collapse during sleep resulting in chronic and repetitive hypoxia, hypercapnia, subsequent arousal and fragmented sleep. Symptoms are insidious and diagnosis is usually delayed. Moderate to severe OSA has serious health implications with significant increase in all causes of mortality in patients with the condition as compared with unaffected individuals. The prevalence of OSA in the 30-70 year age group is estimated at 27% of males and 11% of females and it increases with age. 80% of affected individuals are obese and as obesity rates rise, so has the prevalence of OSA. An overnight polysomnogram (PSG) is required for a definitive diagnosis of OSA. Imaging has played a fundamental role in the evaluation of the anatomical factors associated with recurrent upper airway collapse and the pathogenesis of OSA. The upper airway is frequently imaged by radiologists, providing an opportunity to detect features that are strongly associated with unsuspected OSA and to raise the possibility of this diagnosis. The gold standard of treatment is continuous positive airway pressure (CPAP) which acts as a pneumatic splint for the upper airway. However, efficacy is frequently limited by poor tolerance; clinicians and patients are increasingly opting for one of a range of surgical procedures. Dedicated imaging protocols can be performed for evaluation of the upper airway to aid surgical planning.

Research paper thumbnail of Endolymphatic Sac Tumor

Otology & Neurotology, 2005

Endolymphatic sac tumors are rare, aggressive vascular tumors of papillary architecture that orig... more Endolymphatic sac tumors are rare, aggressive vascular tumors of papillary architecture that originate in the sac and have an association with von Hippel-Lindau disease (1). Endolymphatic sac tumors are typically retrolabyrinthine in location, centered in the fovea of the endolymphatic sac along the posterior wall of the temporal bone. They have a significant propensity to spread in a number of ways (2). Mukherji et al. (3) showed a correlation between middle ear spread and the size of tumor. Because of the anatomic complexity of the temporal bone, it is important to investigate these tumors radiologically in three dimensions before outlining a management plan (4). Computed tomography (CT) and magnetic resonance imaging (MRI) studies (Figs. 1–3) are required for full assessment of endolymphatic sac tumors. Both MRI and CT studies demonstrate the characteristic retrolabyrinthine modalities and locations of tumor, as well as specific findings for each imaging method. CT examination optimally demonstrates the ill-defined bone destruction of the posterior wall of the temporal bone, central spiculated calcification within the tumor matrix in the majority of cases, and usually a thin rim of calcification along the posterior wall of the tumor. MRI examination demonstrates high-signal foci secondary to hemorrhage within or at the margin of endolymphatic sac tumors on a T1-weighted, unenhanced sequence in 80% of cases. Flow voids (focal low-signal punctate or serpiginous foci) are seen in tumors greater than 2 cm in diameter. All tumors show heterogeneous enhancement

Research paper thumbnail of Rotation of the osseous spiral lamina from the hook region along the basal turn of the cochlea: results of a magnetic resonance image anatomical study using high-resolution DRIVE sequences

Surgical and Radiologic Anatomy, 2011

To define the rotational anatomy of the osseous spiral lamina (OSL) at the hook region and along ... more To define the rotational anatomy of the osseous spiral lamina (OSL) at the hook region and along the basal turn of the cochlea and to illustrate the potential utility of high-resolution MRI images to study inner ear ultrastructure. Retrospective review of high-resolution temporal bone MRI images in 20 consecutive adult patients referred for imaging unrelated to hearing loss. The main outcome measure utilised images in an oblique sagittal plane to measure the rotation of the OSL relative to the vertical axis in the hook region and along the basal turn of the cochlea. The right OSL is noted to rotate in a clockwise direction as one proceeds anteriorly; over the same distance, the left OSL rotates in an anti-clockwise direction. The average overall rotation for all subjects as measured over a distance of 1-7 mm from the posterior margin of the round window was 25.95°. Inter-subject variability was noted. Prominent rotation of the OSL was noted in the hook region, this being most pronounced in the proximity to the round window. This concept may have implications for cochleostomy site selection with implant surgery. The study highlights the feasibility of high-resolution MRI to be used to systematically study variations in intra-cochlear anatomy.

Research paper thumbnail of Computed tomography of the temporomandibular joint

Journal of Medical Imaging and Radiation Oncology, 2012

Computed tomography (CT) of the temporo-mandibular joint (TMJ) has only been occasionally reporte... more Computed tomography (CT) of the temporo-mandibular joint (TMJ) has only been occasionally reported. As CT techniques improve, more detailed information is available. Though conventional radiography of the TMJ can supply sufficient diagnostic detail, it may well be replaced by CT as a preliminary examination, as it is able to offer more information with less radiation and minimal patient discomfort.

Research paper thumbnail of Dental panoramic tomography: An approach for the general radiologist

Australasian Radiology, 2006

Dental panoramic tomography is commonly presented to radiologists with no dental training for int... more Dental panoramic tomography is commonly presented to radiologists with no dental training for interpretation. An overview of the technique, basic anatomy and nomenclature and common pathology is presented with examples to show the anatomy and nomenclature, the artefacts and common pathology.

Research paper thumbnail of Current concepts in maxillofacial imaging

European Journal of Radiology, 2008

A review of state-of-the-art maxillofacial imaging is presented. Current imaging techniques inclu... more A review of state-of-the-art maxillofacial imaging is presented. Current imaging techniques include intra-oral radiographs, dental panoramic tomography, multidetector helical computed tomography, cone-beam computed tomography (CBCT) and magnetic resonance imaging (MRI). The commonest conditions encountered in clinical radiological practice are reviewed, including maxillofacial deformities, complicated dental impactions, maxillofacial trauma, jaw lesions (cysts, neoplasms, fibro-osseous lesions (FOLs) and infections), and temporomandibular joint pathology. Pre-operative assessment for dental implant placement is also briefly reviewed.