Antonio Brito - Academia.edu (original) (raw)

Papers by Antonio Brito

Research paper thumbnail of A comparative study of chromosomal polymorphism in certain south american species of Drosophila

Research paper thumbnail of Metaplastic carcinoma of the breast, an unusual disease with worse prognosis: the experience of the European Institute of Oncology and review of the literature

Breast Cancer Research and Treatment, 2007

Background Metaplastic carcinoma of the breast is a rare form of breast cancer and has an uncerta... more Background Metaplastic carcinoma of the breast is a rare form of breast cancer and has an uncertain prognostic significance. The purpose of the present study was to compare the clinical course, and prognosis, between this type of tumor and poorly differentiated ductal carcinoma. Patients and methods We analyzed 37 cases of metaplastic carcinoma of the breast treated at our institution (European Institute of Oncology in Milan, Italy) between 1997 and 2004, comparing them with 72 cases (control group) of poorly differentiated ductal carcinoma. All 109 patients had negative receptors and were G3 at final histology. The control cases were matched according to year of surgery, pT (pT1 vs. pT2/3/4), and pN (absent vs. present). Results Of the 37 patients, eleven died from disease progression, eight developed metastatic disease and two experienced local recurrence. In the control group (72 patients) we observed three deaths due to disease progression, 13 distant metastases, and two local recurrences. Conclusion The overall survival in the metaplastic carcinoma group was significantly worse than in the control group. As regards to disease-free survival, there was no statistically significant difference between the two groups.

Research paper thumbnail of Trends in Drug Resistance, Serotypes, and Molecular Types of Streptococcus pneumoniae Colonizing Preschool-Age Children Attending Day Care Centers in Lisbon, Portugal: a Summary of 4 Years of Annual Surveillance

Journal of Clinical Microbiology, 2005

Research paper thumbnail of A Simplified Analysis of Reaction and Mass Transfer in UASB and EGSB Reactors

Environmental Technology, 1997

Research paper thumbnail of Synthesis of Reprogrammable Control Unit for Combinatorial Processor

  This paper describes the synthesis and implementation of Reprogrammable Control Units (RCU) o... more   This paper describes the synthesis and implementation of Reprogrammable Control Units (RCU) on the base of FPGAs. The mathematical model of RCU is a traditional Finite State Machine (FSM).

Research paper thumbnail of Reconfigurable Hardware SAT Solvers: A Survey of Systems

By adapting to computations that are not so well supported by general-purpose processors, reconfi... more By adapting to computations that are not so well supported by general-purpose processors, reconfigurable systems achieve significant increases in performance. Such computational systems use high-capacity programmable logic devices and are based on processing units customized to the requirements of a particular application. A great deal of research effort in this area is aimed at accelerating the solution of combinatorial optimization problems. Special attention was given to the Boolean satisfiability (SAT) problem resulting in a considerable number of different architectures being proposed. This paper presents the state-of-the-art in reconfigurable hardware SAT satisfiers. The analysis of existing systems has been performed according to such criteria as reconfiguration modes, the execution model, the programming model, etc.

Research paper thumbnail of Hierarchical Specification and Implementation of Combinatorial Algorithms Based on RHS Model

The paper introduces RHS model for combinatorial computations that describes partitioning of the ... more The paper introduces RHS model for combinatorial computations that describes partitioning of the problem between reconfigurable hardware (RH) implemented in FPGA and software (S) running on host computer and specifies the respective communication mechanisms. It is shown that such model is very efficient for the considered scope. It follows from two important characteristics of combinatorial problems. Firstly, each particular problem requires very limited number of taskspecific operations that have to be repeated a huge number of times. Secondly, majority of operations is unique, i.e. task-oriented. The proposed specification method is based on graphical language that extends hierarchical graph-schemes.

Research paper thumbnail of Integrating Robotics Software

Developing software for controlling robotic systems is costly due to the complexity inherent in t... more Developing software for controlling robotic systems is costly due to the complexity inherent in these systems. There is a need for tools that permit a reduction in the programming efforts, aiming at the generation of modular and robust applications, and promoting software reuse. The techniques which are of common use today in other areas are not adequate to deal with the complexity associated with these systems. In this work we present CoolBOT, a component oriented framework for programming robotic systems, based on the Port Automata model that fosters controllability and observability of software components. A simple demonstrator outlines the bene ts of using the proposed approach in the development of a robotic application.

Research paper thumbnail of Development System for FPGA-Based Digital Circuits

The paper discusses some new hardware and software tools that can be used for the design of virtu... more The paper discusses some new hardware and software tools that can be used for the design of virtual circuits based on dynamically reconfigurable FPGAs. With the aid of these tools we can implement a system that requires some, hardware resources Rc, on available hardware that has resources Rh, where Rc>Rh. The main idea of the approach supported by these tools is the rational combination of FPGA capabilities with some proposed methods for producing a modifiable specification, together with a novel technique for architectural and logic synthesis, which has been incorporated into the new design environment

Research paper thumbnail of Nuclear Polyhedrosis Virus: A Possible Example of De Novo Intranuclear Membrane Morphogenesis

Journal of General Virology, 1973

Research paper thumbnail of A comparative study of chromosomal polymorphism in certain south american species of Drosophila

Research paper thumbnail of Metaplastic carcinoma of the breast, an unusual disease with worse prognosis: the experience of the European Institute of Oncology and review of the literature

Breast Cancer Research and Treatment, 2007

Background Metaplastic carcinoma of the breast is a rare form of breast cancer and has an uncerta... more Background Metaplastic carcinoma of the breast is a rare form of breast cancer and has an uncertain prognostic significance. The purpose of the present study was to compare the clinical course, and prognosis, between this type of tumor and poorly differentiated ductal carcinoma. Patients and methods We analyzed 37 cases of metaplastic carcinoma of the breast treated at our institution (European Institute of Oncology in Milan, Italy) between 1997 and 2004, comparing them with 72 cases (control group) of poorly differentiated ductal carcinoma. All 109 patients had negative receptors and were G3 at final histology. The control cases were matched according to year of surgery, pT (pT1 vs. pT2/3/4), and pN (absent vs. present). Results Of the 37 patients, eleven died from disease progression, eight developed metastatic disease and two experienced local recurrence. In the control group (72 patients) we observed three deaths due to disease progression, 13 distant metastases, and two local recurrences. Conclusion The overall survival in the metaplastic carcinoma group was significantly worse than in the control group. As regards to disease-free survival, there was no statistically significant difference between the two groups.

Research paper thumbnail of Trends in Drug Resistance, Serotypes, and Molecular Types of Streptococcus pneumoniae Colonizing Preschool-Age Children Attending Day Care Centers in Lisbon, Portugal: a Summary of 4 Years of Annual Surveillance

Journal of Clinical Microbiology, 2005

Research paper thumbnail of A Simplified Analysis of Reaction and Mass Transfer in UASB and EGSB Reactors

Environmental Technology, 1997

Research paper thumbnail of Synthesis of Reprogrammable Control Unit for Combinatorial Processor

  This paper describes the synthesis and implementation of Reprogrammable Control Units (RCU) o... more   This paper describes the synthesis and implementation of Reprogrammable Control Units (RCU) on the base of FPGAs. The mathematical model of RCU is a traditional Finite State Machine (FSM).

Research paper thumbnail of Reconfigurable Hardware SAT Solvers: A Survey of Systems

By adapting to computations that are not so well supported by general-purpose processors, reconfi... more By adapting to computations that are not so well supported by general-purpose processors, reconfigurable systems achieve significant increases in performance. Such computational systems use high-capacity programmable logic devices and are based on processing units customized to the requirements of a particular application. A great deal of research effort in this area is aimed at accelerating the solution of combinatorial optimization problems. Special attention was given to the Boolean satisfiability (SAT) problem resulting in a considerable number of different architectures being proposed. This paper presents the state-of-the-art in reconfigurable hardware SAT satisfiers. The analysis of existing systems has been performed according to such criteria as reconfiguration modes, the execution model, the programming model, etc.

Research paper thumbnail of Hierarchical Specification and Implementation of Combinatorial Algorithms Based on RHS Model

The paper introduces RHS model for combinatorial computations that describes partitioning of the ... more The paper introduces RHS model for combinatorial computations that describes partitioning of the problem between reconfigurable hardware (RH) implemented in FPGA and software (S) running on host computer and specifies the respective communication mechanisms. It is shown that such model is very efficient for the considered scope. It follows from two important characteristics of combinatorial problems. Firstly, each particular problem requires very limited number of taskspecific operations that have to be repeated a huge number of times. Secondly, majority of operations is unique, i.e. task-oriented. The proposed specification method is based on graphical language that extends hierarchical graph-schemes.

Research paper thumbnail of Integrating Robotics Software

Developing software for controlling robotic systems is costly due to the complexity inherent in t... more Developing software for controlling robotic systems is costly due to the complexity inherent in these systems. There is a need for tools that permit a reduction in the programming efforts, aiming at the generation of modular and robust applications, and promoting software reuse. The techniques which are of common use today in other areas are not adequate to deal with the complexity associated with these systems. In this work we present CoolBOT, a component oriented framework for programming robotic systems, based on the Port Automata model that fosters controllability and observability of software components. A simple demonstrator outlines the bene ts of using the proposed approach in the development of a robotic application.

Research paper thumbnail of Development System for FPGA-Based Digital Circuits

The paper discusses some new hardware and software tools that can be used for the design of virtu... more The paper discusses some new hardware and software tools that can be used for the design of virtual circuits based on dynamically reconfigurable FPGAs. With the aid of these tools we can implement a system that requires some, hardware resources Rc, on available hardware that has resources Rh, where Rc>Rh. The main idea of the approach supported by these tools is the rational combination of FPGA capabilities with some proposed methods for producing a modifiable specification, together with a novel technique for architectural and logic synthesis, which has been incorporated into the new design environment

Research paper thumbnail of Nuclear Polyhedrosis Virus: A Possible Example of De Novo Intranuclear Membrane Morphogenesis

Journal of General Virology, 1973