Anu Altangerel - Academia.edu (original) (raw)
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National Centre of Scientific Research "DEMOKRITOS"
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Papers by Anu Altangerel
Biomedical and pharmacology journal/Biomedical & pharmacology journal, Mar 20, 2024
Central Asian Journal of Medical Sciences
Objectives: Our study’s objective was to investigate the cardioprotective effects of Astragalus m... more Objectives: Our study’s objective was to investigate the cardioprotective effects of Astragalus mongholicus Bunge, a herbal medicine cultivated in Mongolia. Methods: Fifty rats were divided into five groups of ten. The untreated control and treatment group rats received isoproterenol (150 mg/kg) by subcutaneous injection for two consecutive days on 29th and 30th days to induce myocardial infarction. The treatment groups received Astragalus mongholicus Bunge 71, 142, or 284 mg/kg for 28 days prior to infarction. At the end of the experiment, Astragalus mongholicus Bunge’s cardioprotective effect was assessed through histopathology, the measurement of serum CK, AST, ALT, and LDH, and the oxidative stress markers malondialdehyde and total superoxide dismutase. Results: Treatment with Astragalus mongholicus Bunge 71 mg/kg caused significant decreases in the levels of LDH, AST, and CK serum compared with the control group (p < 0.05). Treatment with Astragalus mongholicus Bunge at 71, ...
Biomedical and pharmacology journal/Biomedical & pharmacology journal, Mar 20, 2024
Central Asian Journal of Medical Sciences
Objectives: Our study’s objective was to investigate the cardioprotective effects of Astragalus m... more Objectives: Our study’s objective was to investigate the cardioprotective effects of Astragalus mongholicus Bunge, a herbal medicine cultivated in Mongolia. Methods: Fifty rats were divided into five groups of ten. The untreated control and treatment group rats received isoproterenol (150 mg/kg) by subcutaneous injection for two consecutive days on 29th and 30th days to induce myocardial infarction. The treatment groups received Astragalus mongholicus Bunge 71, 142, or 284 mg/kg for 28 days prior to infarction. At the end of the experiment, Astragalus mongholicus Bunge’s cardioprotective effect was assessed through histopathology, the measurement of serum CK, AST, ALT, and LDH, and the oxidative stress markers malondialdehyde and total superoxide dismutase. Results: Treatment with Astragalus mongholicus Bunge 71 mg/kg caused significant decreases in the levels of LDH, AST, and CK serum compared with the control group (p < 0.05). Treatment with Astragalus mongholicus Bunge at 71, ...