Arkady Voloshin - Academia.edu (original) (raw)

Papers by Arkady Voloshin

Research paper thumbnail of Modeling Cell Movement on a Substrate with Variable Rigidity

International journal of biomedical engineering and science, Jan 30, 2016

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Research paper thumbnail of In-plane strain measurement by digital image correlation

Journal of the Brazilian Society of Mechanical Sciences and Engineering, 2003

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Research paper thumbnail of Monitoring system of a passenger placed in/on a vehicle safety seat

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Research paper thumbnail of Impact Propagation and its Effects on the Human Body

Biomechanics in Sport

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Research paper thumbnail of Enhancement of the shadow-moiré method through digital image processing

Experimental Mechanics, 1993

Surface topography can be conveniently investigated by a well-known shadow-moir technique. It is ... more Surface topography can be conveniently investigated by a well-known shadow-moir technique. It is relatively free from stringent requirements on stability of instrumentation and quality of the light source. The main unresolved problem of the shadow moir is its relatively low resolution. The digital-image-analysis enhanced shadow-moir technique described here is based on the marriage of two well-known and developed methods: classical

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Research paper thumbnail of Cyclic Impacts on Heel Strike 1986

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Research paper thumbnail of Biomechanical characterization and modeling of human mesenchymal stem cells under compression

Computer Methods in Biomechanics and Biomedical Engineering, Jan 21, 2022

The application of microelectromechanical systems (MEMS) in biomedical devices has expanded vastl... more The application of microelectromechanical systems (MEMS) in biomedical devices has expanded vastly over the last few decades, with MEMS devices being developed to measure different characteristics of cells. The study of cell mechanics offers valuable understanding of cell viability and functionality. Cell biomechanics approaches also facilitate the characterization of important cell and tissue behaviors. In particular, understanding of the biological response of cells to their biomechanical environment would enhance the knowledge of how cellular responses correlate to tissue level characteristics and how some diseases, such as cancer, grow in the body. This study focuses on viscoelastic modeling of the behavior of a single suspended human mesenchymal stem cell (hMSC). Mechanical properties of hMSC cells are particularly important in tissue engineering and research for the treatment of cardiovascular diseases. We evaluated the elastic and viscoelastic properties of hMSC cells using a miniaturized custom-made BioMEMS device. Our results were compared to the elastic and viscoelastic properties measured by other methods such as atomic force microscopy (AFM) and micropipette aspiration. Different approaches were applied to model the experimentally obtained force data, including elastic and Standard Linear Solid (SLS) constitutive models, and the corresponding constants were derived. These values were compared to the ones in literature that were based on micropipette aspiration and AFM methods. We then utilized a tensegrity approach to model major parts of the internal structure of the cell and treat the cell as a network of viscoelastic microtubules and microfilaments, as opposed to a simple spherical blob. The results predicted from the tensegrity model were similar to the recorded experimental data.

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Research paper thumbnail of Effect of thermal loading on the deformations of the optoelectronic package: a moire interferometry approach

Proceedings of SPIE, Oct 25, 2004

Effect of thermal loading on the deformations of the optoelectronic package: a moire interferomet... more Effect of thermal loading on the deformations of the optoelectronic package: a moire interferometry approach. [Proceedings of SPIE 5595, 428 (2004)]. Arkady S. Voloshin. Abstract. Advance optoelectronic packaging is dependent ...

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Research paper thumbnail of <title>Accuracy of whole-field mapping by Jones matrix Fourier photopolarimeter</title>

Proceedings of SPIE, Jun 14, 2000

ABSTRACT A whole-field polarimetric method through digital image processing has been developed fo... more ABSTRACT A whole-field polarimetric method through digital image processing has been developed for mapping the three optical parameters, which determine normalized Jones matrix of an elliptic retarder. The suggested technique conveys measurement data sufficient to describe optical anisotropy in the media exhibiting rotation of birefringence axes along the light path. Particularly, homogeneous or inhomogeneous birefringent gyrotropic objects and initially isotropic transparent samples bearing stress-induced anisotropy can be investigated by use of this technique. Operational principle of the method implies incremental rotation of polarizer and analyzer with the ratio 1:3 over the revolution of the polarizer and collection of 9 intensity images between successive rotation steps. Then thus obtained intensity patterns are digitally processed by use of Fourier analysis. Specifically in this paper we address issues concerning the accuracy of mapping all the three parameters at different values of those. Some ad hoc experiments with test crystalline quartz phase plates are reported. Computer simulations and measurement results are presented and discussed.

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Research paper thumbnail of Validation of Smartphone Sway Analysis for Fall Prevention

Applied sciences, Nov 10, 2021

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Research paper thumbnail of A least-squares approach for evaluating stress intensity factors from mixed-mode caustics

Engineering Fracture Mechanics, 1991

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Research paper thumbnail of Reliability and Validity of Goniometric Turnout Measurements Compared with MRI and Retro-Reflective Markers

Journal of dance medicine & science : official publication of the International Association for Dance Medicine & Science, Dec 1, 2008

There is no consensus on a valid and reliable method of measuring turnout. However, there is a bu... more There is no consensus on a valid and reliable method of measuring turnout. However, there is a building awareness that such measures need to exist. Total turnout is the sum of hip rotation, tibial torsion, and contributions from the foot. To our knowledge, there has been no research that directly measures and then sums each individual component of turnout to verify a total turnout value. Furthermore, the tibial torsion component has not previously been confirmed by an imaging study. The purpose of this study was to test the validity and reliability of a single total passive turnout (TPT) test taken with a goniometer by comparing it with the sum of the individual components. Fourteen female dancers were recruited as participants. Measurements of the subjects&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; right and left legs were gathered for the components of turnout. Tibial torsion was measured using Magnetic Resonance Imaging (MRI). Retro-reflective marker assisted measurements were used to calculate the static components of TPT. Hip external rotation, TPT, and total active turnout (TAT) were measured by goniometer. Additional standing turnout values were collected on rotational disks. Tibial torsion and hip rotation were summed and compared with three whole-leg turnout values using Two-Tailed T-Tests and Pearson product-moment correlation coefficients. Tibial torsion measurements in dancers were found to demonstrate substantial variation between subjects and between legs in the same subject. The range on the right leg was 16 degrees to 60 degrees, and the range on the left leg was 16 degrees to 52 degrees. Retro-reflective markers and biomechanical theory demonstrated that when the knee is extended and locked, &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;screwed home,&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; it will not factor into a whole-leg turnout value. TAT and turnout on the disks were not statistically significant when compared with the summed total. Statistical significance was achieved in four of the eight measurement series comparing TPT with the summed value of tibial torsion and hip rotation. The advantages of a standard, valid, and reliable method of measuring turnout are many, and the risks are few. Some advantages include improved training techniques, mastery of the use of turnout at an earlier age, better dancer and teacher compliance with suggested turnout rates, understanding the use of parallel position, understanding the etiology of many dance-related injuries, and possible development of preventative measures.

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Research paper thumbnail of Electronic Packaging

Taylor & Francis eBooks, Dec 1, 2003

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Research paper thumbnail of Transient Stress Intensity Factors for Thermally Loaded Edge-Cracked Plates

Journal of Thermal Stresses, Apr 1, 1993

Page 1. TRANSIENT STRESS INTENSITY FACTORS FOR THERMALLY LOADED EDGE-CRACKED PLATES Ravi Mahqjan ... more Page 1. TRANSIENT STRESS INTENSITY FACTORS FOR THERMALLY LOADED EDGE-CRACKED PLATES Ravi Mahqjan and Arkady S. Voloshin Department of Mechanical Engineering and Mechanics Lehigh Uniuersi&amp;amp; Bethlehem, Pennsylvania 18015 ...

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Research paper thumbnail of Modeling Cell Spreading and Alignment on Micro-WavySurfaces

Cmes-computer Modeling in Engineering & Sciences, Mar 1, 2014

ABSTRACT Mechanical behavior of cells plays a crucial role in response to external stimuli and en... more ABSTRACT Mechanical behavior of cells plays a crucial role in response to external stimuli and environment. It is very important to elucidate the mechanisms of cellular activities like spreading and alignment as it would shed light on further biological concepts. In this study, a multi-scale computational approach is adopted by modeling the cytoskeleton of cell as a tensegrity structure. The model is based on the complementary force balance between the tension and compression elements, resembling the internal structure of cell cytoskeleton composed of microtubules and actin filaments. The effect of surface topology on strain energy of a spread cell is investigated by defining strain energy of the structure as the main criterion in the simulation process of the cell spreading. Spreading as a way to decrease internal energy toward a minimum energy state is the main hypothesis that is investigated. The cell model is placed at different positions along the wavy surface and the spreading and alignment behavior is observed. The implementation of the model illustrates the effect of topological factors on spreading and alignment of the cell. Experiments were conducted by seeding Bovine Aortic Endothelial Cells (BAECs) on poly (dimethylsiloxane) (PDMS) wavy surface to serve as a verification for the proposed model in the context of cellular behavior. Experimental observations are in general agreement with the computational results, which points out that the model can be explanatory in terms of understanding mechanical characteristics of cells.

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Research paper thumbnail of Biomechanical aspects of high heel gait

Journal of Biomechanics, 1987

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Research paper thumbnail of Synergy of Material, Structure and Cell

Research & development in materials science, Oct 23, 2017

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Research paper thumbnail of Application of Stereo-Digital Image Correlation to Full-Field 3-D Deformation Measurement of Intervertebral Disc

Strain, Jan 8, 2010

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Research paper thumbnail of A polymer V-shaped electrothermal actuator array for biological applications

Journal of Micromechanics and Microengineering, Jun 9, 2008

Page 1. A polymer V-shaped electrothermal actuator array for biological applications This article... more Page 1. A polymer V-shaped electrothermal actuator array for biological applications This article has been downloaded from IOPscience. Please scroll down to see the full text article. 2008 J. Micromech. Microeng. 18 075020 (http://iopscience.iop.org/0960-1317/18/7/075020) ...

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Research paper thumbnail of The influence of walking speed on dynamic loading on the human musculoskeletal system

Medicine and Science in Sports and Exercise, Jun 1, 2000

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Research paper thumbnail of Modeling Cell Movement on a Substrate with Variable Rigidity

International journal of biomedical engineering and science, Jan 30, 2016

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Research paper thumbnail of In-plane strain measurement by digital image correlation

Journal of the Brazilian Society of Mechanical Sciences and Engineering, 2003

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Research paper thumbnail of Monitoring system of a passenger placed in/on a vehicle safety seat

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Impact Propagation and its Effects on the Human Body

Biomechanics in Sport

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Research paper thumbnail of Enhancement of the shadow-moiré method through digital image processing

Experimental Mechanics, 1993

Surface topography can be conveniently investigated by a well-known shadow-moir technique. It is ... more Surface topography can be conveniently investigated by a well-known shadow-moir technique. It is relatively free from stringent requirements on stability of instrumentation and quality of the light source. The main unresolved problem of the shadow moir is its relatively low resolution. The digital-image-analysis enhanced shadow-moir technique described here is based on the marriage of two well-known and developed methods: classical

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Cyclic Impacts on Heel Strike 1986

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Biomechanical characterization and modeling of human mesenchymal stem cells under compression

Computer Methods in Biomechanics and Biomedical Engineering, Jan 21, 2022

The application of microelectromechanical systems (MEMS) in biomedical devices has expanded vastl... more The application of microelectromechanical systems (MEMS) in biomedical devices has expanded vastly over the last few decades, with MEMS devices being developed to measure different characteristics of cells. The study of cell mechanics offers valuable understanding of cell viability and functionality. Cell biomechanics approaches also facilitate the characterization of important cell and tissue behaviors. In particular, understanding of the biological response of cells to their biomechanical environment would enhance the knowledge of how cellular responses correlate to tissue level characteristics and how some diseases, such as cancer, grow in the body. This study focuses on viscoelastic modeling of the behavior of a single suspended human mesenchymal stem cell (hMSC). Mechanical properties of hMSC cells are particularly important in tissue engineering and research for the treatment of cardiovascular diseases. We evaluated the elastic and viscoelastic properties of hMSC cells using a miniaturized custom-made BioMEMS device. Our results were compared to the elastic and viscoelastic properties measured by other methods such as atomic force microscopy (AFM) and micropipette aspiration. Different approaches were applied to model the experimentally obtained force data, including elastic and Standard Linear Solid (SLS) constitutive models, and the corresponding constants were derived. These values were compared to the ones in literature that were based on micropipette aspiration and AFM methods. We then utilized a tensegrity approach to model major parts of the internal structure of the cell and treat the cell as a network of viscoelastic microtubules and microfilaments, as opposed to a simple spherical blob. The results predicted from the tensegrity model were similar to the recorded experimental data.

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Research paper thumbnail of Effect of thermal loading on the deformations of the optoelectronic package: a moire interferometry approach

Proceedings of SPIE, Oct 25, 2004

Effect of thermal loading on the deformations of the optoelectronic package: a moire interferomet... more Effect of thermal loading on the deformations of the optoelectronic package: a moire interferometry approach. [Proceedings of SPIE 5595, 428 (2004)]. Arkady S. Voloshin. Abstract. Advance optoelectronic packaging is dependent ...

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Research paper thumbnail of <title>Accuracy of whole-field mapping by Jones matrix Fourier photopolarimeter</title>

Proceedings of SPIE, Jun 14, 2000

ABSTRACT A whole-field polarimetric method through digital image processing has been developed fo... more ABSTRACT A whole-field polarimetric method through digital image processing has been developed for mapping the three optical parameters, which determine normalized Jones matrix of an elliptic retarder. The suggested technique conveys measurement data sufficient to describe optical anisotropy in the media exhibiting rotation of birefringence axes along the light path. Particularly, homogeneous or inhomogeneous birefringent gyrotropic objects and initially isotropic transparent samples bearing stress-induced anisotropy can be investigated by use of this technique. Operational principle of the method implies incremental rotation of polarizer and analyzer with the ratio 1:3 over the revolution of the polarizer and collection of 9 intensity images between successive rotation steps. Then thus obtained intensity patterns are digitally processed by use of Fourier analysis. Specifically in this paper we address issues concerning the accuracy of mapping all the three parameters at different values of those. Some ad hoc experiments with test crystalline quartz phase plates are reported. Computer simulations and measurement results are presented and discussed.

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Research paper thumbnail of Validation of Smartphone Sway Analysis for Fall Prevention

Applied sciences, Nov 10, 2021

Bookmarks Related papers MentionsView impact

Research paper thumbnail of A least-squares approach for evaluating stress intensity factors from mixed-mode caustics

Engineering Fracture Mechanics, 1991

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Reliability and Validity of Goniometric Turnout Measurements Compared with MRI and Retro-Reflective Markers

Journal of dance medicine & science : official publication of the International Association for Dance Medicine & Science, Dec 1, 2008

There is no consensus on a valid and reliable method of measuring turnout. However, there is a bu... more There is no consensus on a valid and reliable method of measuring turnout. However, there is a building awareness that such measures need to exist. Total turnout is the sum of hip rotation, tibial torsion, and contributions from the foot. To our knowledge, there has been no research that directly measures and then sums each individual component of turnout to verify a total turnout value. Furthermore, the tibial torsion component has not previously been confirmed by an imaging study. The purpose of this study was to test the validity and reliability of a single total passive turnout (TPT) test taken with a goniometer by comparing it with the sum of the individual components. Fourteen female dancers were recruited as participants. Measurements of the subjects&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; right and left legs were gathered for the components of turnout. Tibial torsion was measured using Magnetic Resonance Imaging (MRI). Retro-reflective marker assisted measurements were used to calculate the static components of TPT. Hip external rotation, TPT, and total active turnout (TAT) were measured by goniometer. Additional standing turnout values were collected on rotational disks. Tibial torsion and hip rotation were summed and compared with three whole-leg turnout values using Two-Tailed T-Tests and Pearson product-moment correlation coefficients. Tibial torsion measurements in dancers were found to demonstrate substantial variation between subjects and between legs in the same subject. The range on the right leg was 16 degrees to 60 degrees, and the range on the left leg was 16 degrees to 52 degrees. Retro-reflective markers and biomechanical theory demonstrated that when the knee is extended and locked, &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;screwed home,&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; it will not factor into a whole-leg turnout value. TAT and turnout on the disks were not statistically significant when compared with the summed total. Statistical significance was achieved in four of the eight measurement series comparing TPT with the summed value of tibial torsion and hip rotation. The advantages of a standard, valid, and reliable method of measuring turnout are many, and the risks are few. Some advantages include improved training techniques, mastery of the use of turnout at an earlier age, better dancer and teacher compliance with suggested turnout rates, understanding the use of parallel position, understanding the etiology of many dance-related injuries, and possible development of preventative measures.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Electronic Packaging

Taylor & Francis eBooks, Dec 1, 2003

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Transient Stress Intensity Factors for Thermally Loaded Edge-Cracked Plates

Journal of Thermal Stresses, Apr 1, 1993

Page 1. TRANSIENT STRESS INTENSITY FACTORS FOR THERMALLY LOADED EDGE-CRACKED PLATES Ravi Mahqjan ... more Page 1. TRANSIENT STRESS INTENSITY FACTORS FOR THERMALLY LOADED EDGE-CRACKED PLATES Ravi Mahqjan and Arkady S. Voloshin Department of Mechanical Engineering and Mechanics Lehigh Uniuersi&amp;amp; Bethlehem, Pennsylvania 18015 ...

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Research paper thumbnail of Modeling Cell Spreading and Alignment on Micro-WavySurfaces

Cmes-computer Modeling in Engineering & Sciences, Mar 1, 2014

ABSTRACT Mechanical behavior of cells plays a crucial role in response to external stimuli and en... more ABSTRACT Mechanical behavior of cells plays a crucial role in response to external stimuli and environment. It is very important to elucidate the mechanisms of cellular activities like spreading and alignment as it would shed light on further biological concepts. In this study, a multi-scale computational approach is adopted by modeling the cytoskeleton of cell as a tensegrity structure. The model is based on the complementary force balance between the tension and compression elements, resembling the internal structure of cell cytoskeleton composed of microtubules and actin filaments. The effect of surface topology on strain energy of a spread cell is investigated by defining strain energy of the structure as the main criterion in the simulation process of the cell spreading. Spreading as a way to decrease internal energy toward a minimum energy state is the main hypothesis that is investigated. The cell model is placed at different positions along the wavy surface and the spreading and alignment behavior is observed. The implementation of the model illustrates the effect of topological factors on spreading and alignment of the cell. Experiments were conducted by seeding Bovine Aortic Endothelial Cells (BAECs) on poly (dimethylsiloxane) (PDMS) wavy surface to serve as a verification for the proposed model in the context of cellular behavior. Experimental observations are in general agreement with the computational results, which points out that the model can be explanatory in terms of understanding mechanical characteristics of cells.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Biomechanical aspects of high heel gait

Journal of Biomechanics, 1987

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Synergy of Material, Structure and Cell

Research & development in materials science, Oct 23, 2017

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Application of Stereo-Digital Image Correlation to Full-Field 3-D Deformation Measurement of Intervertebral Disc

Strain, Jan 8, 2010

Bookmarks Related papers MentionsView impact

Research paper thumbnail of A polymer V-shaped electrothermal actuator array for biological applications

Journal of Micromechanics and Microengineering, Jun 9, 2008

Page 1. A polymer V-shaped electrothermal actuator array for biological applications This article... more Page 1. A polymer V-shaped electrothermal actuator array for biological applications This article has been downloaded from IOPscience. Please scroll down to see the full text article. 2008 J. Micromech. Microeng. 18 075020 (http://iopscience.iop.org/0960-1317/18/7/075020) ...

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Research paper thumbnail of The influence of walking speed on dynamic loading on the human musculoskeletal system

Medicine and Science in Sports and Exercise, Jun 1, 2000

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