Arzu Canan - Academia.edu (original) (raw)

Papers by Arzu Canan

Research paper thumbnail of Pre- and Postprocedure Imaging of Transcatheter Pulmonary Valve Implantation

Research paper thumbnail of Superdominant Left Circumflex Artery with Absent Right Coronary Artery

Radiology

Three-dimensional cinematic rendered images of a heart demonstrate superdominant left circumflex ... more Three-dimensional cinematic rendered images of a heart demonstrate superdominant left circumflex (LCX) artery supplying the right coronary artery territory. LAD = left anterior descending artery. Disclosures of conflicts of interest: A.C. No relevant relationships. K.B. No relevant relationships.

Research paper thumbnail of Changes in the size of breast lesions during menstrual cycle observed by ultrasound: An initial study

Biomedical Research-tokyo, 2017

Purpose: We aimed to evaluate changes in size of breast lesions during menstrual phases. Material... more Purpose: We aimed to evaluate changes in size of breast lesions during menstrual phases. Material and Methods: In this prospective study, 46 women aged 18-35 years old who were referred to our radiology clinic for breast sonography and had cystic or solid breast lesions larger than 5 mm were enrolled to the study. Breast ultrasound (US) was performed at two different times; one within 5 days before and one within 5 days after menstrual bleeding. Anteroposterior and transverse length of the lesions were measured. Results: In total, 145 breast lesions were detected by US. Of these lesions, 6 were visualized in premenstrual phase but were not observed in postmenstrual phase. 6 lesions different were not visualized in premenstrual, but were detected in postmenstrual phase. One hundred and twenty-three lesions were visualized by US both in luteal and follicular phases. Conclusions: Timing of breast US might cause false results and unnecessary further investigations. Therefore, we suggest...

Research paper thumbnail of Atypical MRI Findings in Cerebral Adrenoleukodystrophy: a Case Report

Acta Clinica Croatica, 2021

-Adrenoleukodystrophy is a rare X-linked hereditary disease that results in accumulation of very-... more -Adrenoleukodystrophy is a rare X-linked hereditary disease that results in accumulation of very-long-chain fatty acids in all body tissues, thus causing demyelination of the white matter. Magnetic resonance imaging (MRI) is a reliable radiological modality to demonstrate the extension of brain lesions and severity of the disease. In the classic form, the parieto-occipital white matter is affected. Besides, atypical MRI findings such as primary frontal lobe involvement are rarely described. We report a case of adrenoleukodystrophy presenting with rare MRI findings such as bilateral symmetric frontal lobe white matter changes suggesting anterior predominance.

Research paper thumbnail of Extrinsic compression of coronary and pulmonary vasculature

Cardiovascular Diagnosis and Therapy, 2021

Coronary artery disease from atherosclerosis induced stenosis remains the leading cause of acute ... more Coronary artery disease from atherosclerosis induced stenosis remains the leading cause of acute coronary syndrome (ACS) and death worldwide, however extrinsic compression of coronary arteries from adjacent anatomical and pathological structures is an infrequent but important diagnosis to be aware of, especially given the nonspecific symptoms of chest pain that mimic angina in patients with pulmonary hypertension (PHT) and congenital heart disease. Non-invasive CT angiography is an invaluable diagnostic tool for detection of coronary artery compression, pulmonary artery dilatation and pulmonary vascular compression. Although established guidelines are not available for management of left main coronary artery (LMCA) compression syndrome, percutaneous coronary intervention and stent implantation remain a feasible option for the treatment, specifically for patients with a high surgical risk. Treatment of pulmonary vein or artery compression is more varied and determined by etiology. This review article is focused on detailed discussion of extrinsic compression of coronary arteries, mainly the LMCA and brief discussion on pulmonary vasculature compression by surrounding anatomical and pathological entities, with focus on pathophysiology, clinical features, complications and role of imaging in its diagnosis and management.

Research paper thumbnail of CAD-RADS: Pushing the Limits

Research paper thumbnail of Multimodality Imaging of Transposition of the Great Arteries

RadioGraphics, 2021

Transposition of the great arteries (TGA) is a congenital conotruncal abnormality characterized b... more Transposition of the great arteries (TGA) is a congenital conotruncal abnormality characterized by discordant connections between the ventricles and great arteries, with the aorta originating from the right ventricle (RV), and the pulmonary artery (PA) originating from the left ventricle (LV). The two main types of TGA are complete transposition or dextro-transposition of the great arteries (D-TGA), commonly referred to as d-loop, and congenitally corrected transposition (CCTGA), commonly referred to as l-loop or L-TGA. In D-TGA, the connections between the ventricles and atria are concordant, whereas in CCTGA they are discordant, with the left atrium connected to the RV, and the right atrium connected to the LV. D-TGA manifests during the neonatal period and can be surgically managed by atrial switch operation (AtrSO), arterial switch operation (ASO), Rastelli procedure, or Nikaidoh procedure. Arrhythmia, systemic ventricular dysfunction, baffle stenosis, and baffle leak are the common complications of AtrSO, whereas supravalvular pulmonary or branch PA stenosis, neoaortic dilatation, and coronary artery narrowing are the common complications of ASO. CCTGA may manifest late in life, even in adulthood. Surgeries for associated lesions such as tricuspid regurgitation, subpulmonic stenosis, and ventricular septal defect may be performed. A doubleswitch operation that includes both the atrial and arterial switch operations constitutes anatomic correction for CCTGA. Imaging plays an important role in the evaluation of TGA, both before and after surgery, for helping define the anatomy, quantify hemodynamics, and evaluate complications. Transthoracic echocardiography is the first-line imaging modality for presurgical planning in children with TGA. MRI provides comprehensive morphologic and functional information, particularly in adults after surgery. CT is performed when MRI is contraindicated or expected to generate artifacts. The authors review the imaging appearances of TGA, with a focus on pre-and postsurgical imaging.

Research paper thumbnail of Radiological approach to cavitary lung lesions

Postgraduate Medical Journal, 2020

Cavitary lesions in the lung are not an uncommon imaging encounter and carry a broad differential... more Cavitary lesions in the lung are not an uncommon imaging encounter and carry a broad differential diagnosis that includes a wide range of pathological conditions from cancers, infections/inflammatory processes to traumatic and congenital lung abnormalities. In this review article, we describe a comprehensive approach for evaluation of cavitary lung lesions and discuss the differential diagnosis in the light of radiological findings.

Research paper thumbnail of A Rare Pulmonary-Systemic Connection: Levoatriocardinal Vein

Radiology: Cardiothoracic Imaging, 2020

Research paper thumbnail of Rare intrathoracic rib: Significance and associations in and adult

Lung India, 2020

© 2020 Indian Chest Society | Published by Wolters Kluwer Medknow This is an open access journal,... more © 2020 Indian Chest Society | Published by Wolters Kluwer Medknow This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. Access this article online Quick Response Code: Website: www.lungindia.com

Research paper thumbnail of Future Directions in Coronary CT Angiography: CT-Fractional Flow Reserve, Plaque Vulnerability, and Quantitative Plaque Assessment

Korean Circulation Journal, 2020

Coronary computed tomography angiography (CCTA) is a well-validated and noninvasive imaging modal... more Coronary computed tomography angiography (CCTA) is a well-validated and noninvasive imaging modality for the assessment of coronary artery disease (CAD) in patients with stable ischemic heart disease and acute coronary syndromes (ACSs). CCTA not only delineates the anatomy of the heart and coronary arteries in detail, but also allows for intra-and extraluminal imaging of coronary arteries. Emerging technologies have promoted new CCTA applications, resulting in a comprehensive assessment of coronary plaques and their clinical significance. The application of computational fluid dynamics to CCTA resulted in a robust tool for noninvasive assessment of coronary blood flow hemodynamics and determination of hemodynamically significant stenosis. Detailed evaluation of plaque morphology and identification of high-risk plaque features by CCTA have been confirmed as predictors of future outcomes, identifying patients at risk for ACSs. With quantitative coronary plaque assessment, the progression of the CAD or the response to therapy could be monitored by CCTA. The aim of this article is to review the future directions of emerging applications in CCTA, such as computed tomography (CT)-fractional flow reserve, imaging of vulnerable plaque features, and quantitative plaque imaging. We will also briefly discuss novel methods appearing in the coronary imaging scenario, such as machine learning, radiomics, and spectral CT.

Research paper thumbnail of MRI of the Pericardium

Research paper thumbnail of The Relationship of Pulmonary Artery Computed Tomography Obstruction Index Ratio, D-Dimer and Mean Platelet Volume Levels in Pulmonary Embolism

Turkiye Klinikleri Archives of Lung, 2017

Research paper thumbnail of Toraks difüzyon ağırlıklı görüntülemede “b değeri”

Tuberkuloz ve Toraks, 2015

Research paper thumbnail of Magnetic resonance imaging findings of two sisters with Van der Knaap leukoencephalopathy

The neuroradiology journal, 2015

Megalencephalic leukoencephalopathy with subcortical cysts, or Van der Knaap leukoencephalopathy,... more Megalencephalic leukoencephalopathy with subcortical cysts, or Van der Knaap leukoencephalopathy, is a rare disease which is characterised by macrocephaly and neurological disorders with autosomal recessive inheritance. Magnetic resonance imaging is very helpful for determining distinctive findings and distinguishing other diseases. We present the radiological findings of two sisters (aged 6 and 10 years) diagnosed with Van der Knaap leukoencephalopathy.

Research paper thumbnail of Morphometric measurements of the cranium in congenital bilateral blind males and females

Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2013

Cranium dimensions differ according to racial, geopraphic, ethnic and nutritional factors. This s... more Cranium dimensions differ according to racial, geopraphic, ethnic and nutritional factors. This study will shed light on the question: "Is there a difference in the cranial distances measured between congenital bilateral blind people and healthy individuals?" Nine anthropometric measures were performed on the brain MRI midsagittally obtained from male and female congenital bilateral blinds. The anthropometric measures taken included the glabella-opisthocranion, nasion-dorsum sellae, dorsum sellae- opisthocranion, nasion-basion, nasion-opisthion, basion-opisthion, prosthion-basion, basion-vertex and the clival angle. In addition, the supratentorial and infratentorial areas were calculated. Glabella-opisthocranion, nasion-dorsum sellae, nasion-basion, prosthion-basion and clival angle were found to be smaller in the congenital bilateral blind females compared to the healthy group, but these results were not statistically significant. Whereas, other measures out of the basion...

Research paper thumbnail of Multiple tendon xanthomas in patient with heterozygous familial hypercholesterolaemia: sonographic and MRI findings

Research paper thumbnail of Silent ischemic pancreatitis following urosepsis

Journal of Experimental and Clinical Medicine, 2013

Pancreatic ischemia is an uncommon cause of acute pancreatitis. Ischemia with resultant pancreati... more Pancreatic ischemia is an uncommon cause of acute pancreatitis. Ischemia with resultant pancreatitis has been reported in vasculitis, atheroembolism, intraoperative hypotension, survivors of cardiac arrest and hemorrhagic shock. Ischemic acute pancreatitis is difficult to recognize clinically. In this report we present a 63 year old woman with painless ischemic pancreatitis following urosepsis. We suggest that if a critically ill patient is hypotensive for more than 24-48 hours, amylase levels must be monitored to establish ischemic acute pancreatitis (AP) even if the patient remains asymptomatic.

Research paper thumbnail of Bilateral TalamikInfarkt: Percheron Arteri Oklüzyonu

Nöro Psikiyatri Arşivi, 2013

Re cei ved/Ge liş ta ri hi: 04.12.2012 Ac cep ted/Ka bul ta ri hi: 28.12.2012 © Arc hi ves of Neu... more Re cei ved/Ge liş ta ri hi: 04.12.2012 Ac cep ted/Ka bul ta ri hi: 28.12.2012 © Arc hi ves of Neu ropsy chi atry, pub lis hed by Ga le nos Pub lis hing/ © Nö rop si ki yat ri Ar şi vi Der gi si, Ga le nos Ya yı ne vi ta ra f›n dan ba s›l m›fl t›r.

Research paper thumbnail of Mean platelet volume and D-dimer in patients with suspected deep venous thrombosis

Journal of Thrombosis and Thrombolysis, 2012

The aim of this retrospective study was to evaluate the diagnostic value of mean platelet volume ... more The aim of this retrospective study was to evaluate the diagnostic value of mean platelet volume (MPV) and D-dimer for acute deep venous thromboembolism (DVT). Two hundred and fifty six patients who presented to the emergency or cardiovascular surgery department with suspected lower limb DVT were retrospectively recruited. Plasma levels of MPV, platelet count, and D-dimer were obtained and duplex sonography examination was performed for all patients. Eighty four patients had acute DVT which was diagnosed by duplex ultrasonography. MPV was significantly higher in patients with DVT than in those without DVT (p \ 0.01). The mean MPV was 7.97 ± 17.8 and 7.58 ± 0.87 fL in patients with DVT and without DVT, respectively (p \ 0.01). D-dimer was significantly higher in patients with DVT (p \ 0.01). For all the patients, a positive MPV when the cutoff value was 7.3 fL, had 69.7 % sensitivity and 43.9 % specificity. D-dimer (with a cutoff value of 0.5 lg/mL) had 82.9 % sensitivity and 32.7 % specificity. In case of combination of MPV and D-dimer, the specificity exceeded (65.9 %) despite the reduction in sensitivity (59.2 %). Elevated MPV was found to be associated with acute DVT and high levels of MPV might increase the specificity of D-dimer for exclusion of DVT. Keywords D-dimer Á Doppler Á Deep venous thrombosis Á Mean platelet volume

Research paper thumbnail of Pre- and Postprocedure Imaging of Transcatheter Pulmonary Valve Implantation

Research paper thumbnail of Superdominant Left Circumflex Artery with Absent Right Coronary Artery

Radiology

Three-dimensional cinematic rendered images of a heart demonstrate superdominant left circumflex ... more Three-dimensional cinematic rendered images of a heart demonstrate superdominant left circumflex (LCX) artery supplying the right coronary artery territory. LAD = left anterior descending artery. Disclosures of conflicts of interest: A.C. No relevant relationships. K.B. No relevant relationships.

Research paper thumbnail of Changes in the size of breast lesions during menstrual cycle observed by ultrasound: An initial study

Biomedical Research-tokyo, 2017

Purpose: We aimed to evaluate changes in size of breast lesions during menstrual phases. Material... more Purpose: We aimed to evaluate changes in size of breast lesions during menstrual phases. Material and Methods: In this prospective study, 46 women aged 18-35 years old who were referred to our radiology clinic for breast sonography and had cystic or solid breast lesions larger than 5 mm were enrolled to the study. Breast ultrasound (US) was performed at two different times; one within 5 days before and one within 5 days after menstrual bleeding. Anteroposterior and transverse length of the lesions were measured. Results: In total, 145 breast lesions were detected by US. Of these lesions, 6 were visualized in premenstrual phase but were not observed in postmenstrual phase. 6 lesions different were not visualized in premenstrual, but were detected in postmenstrual phase. One hundred and twenty-three lesions were visualized by US both in luteal and follicular phases. Conclusions: Timing of breast US might cause false results and unnecessary further investigations. Therefore, we suggest...

Research paper thumbnail of Atypical MRI Findings in Cerebral Adrenoleukodystrophy: a Case Report

Acta Clinica Croatica, 2021

-Adrenoleukodystrophy is a rare X-linked hereditary disease that results in accumulation of very-... more -Adrenoleukodystrophy is a rare X-linked hereditary disease that results in accumulation of very-long-chain fatty acids in all body tissues, thus causing demyelination of the white matter. Magnetic resonance imaging (MRI) is a reliable radiological modality to demonstrate the extension of brain lesions and severity of the disease. In the classic form, the parieto-occipital white matter is affected. Besides, atypical MRI findings such as primary frontal lobe involvement are rarely described. We report a case of adrenoleukodystrophy presenting with rare MRI findings such as bilateral symmetric frontal lobe white matter changes suggesting anterior predominance.

Research paper thumbnail of Extrinsic compression of coronary and pulmonary vasculature

Cardiovascular Diagnosis and Therapy, 2021

Coronary artery disease from atherosclerosis induced stenosis remains the leading cause of acute ... more Coronary artery disease from atherosclerosis induced stenosis remains the leading cause of acute coronary syndrome (ACS) and death worldwide, however extrinsic compression of coronary arteries from adjacent anatomical and pathological structures is an infrequent but important diagnosis to be aware of, especially given the nonspecific symptoms of chest pain that mimic angina in patients with pulmonary hypertension (PHT) and congenital heart disease. Non-invasive CT angiography is an invaluable diagnostic tool for detection of coronary artery compression, pulmonary artery dilatation and pulmonary vascular compression. Although established guidelines are not available for management of left main coronary artery (LMCA) compression syndrome, percutaneous coronary intervention and stent implantation remain a feasible option for the treatment, specifically for patients with a high surgical risk. Treatment of pulmonary vein or artery compression is more varied and determined by etiology. This review article is focused on detailed discussion of extrinsic compression of coronary arteries, mainly the LMCA and brief discussion on pulmonary vasculature compression by surrounding anatomical and pathological entities, with focus on pathophysiology, clinical features, complications and role of imaging in its diagnosis and management.

Research paper thumbnail of CAD-RADS: Pushing the Limits

Research paper thumbnail of Multimodality Imaging of Transposition of the Great Arteries

RadioGraphics, 2021

Transposition of the great arteries (TGA) is a congenital conotruncal abnormality characterized b... more Transposition of the great arteries (TGA) is a congenital conotruncal abnormality characterized by discordant connections between the ventricles and great arteries, with the aorta originating from the right ventricle (RV), and the pulmonary artery (PA) originating from the left ventricle (LV). The two main types of TGA are complete transposition or dextro-transposition of the great arteries (D-TGA), commonly referred to as d-loop, and congenitally corrected transposition (CCTGA), commonly referred to as l-loop or L-TGA. In D-TGA, the connections between the ventricles and atria are concordant, whereas in CCTGA they are discordant, with the left atrium connected to the RV, and the right atrium connected to the LV. D-TGA manifests during the neonatal period and can be surgically managed by atrial switch operation (AtrSO), arterial switch operation (ASO), Rastelli procedure, or Nikaidoh procedure. Arrhythmia, systemic ventricular dysfunction, baffle stenosis, and baffle leak are the common complications of AtrSO, whereas supravalvular pulmonary or branch PA stenosis, neoaortic dilatation, and coronary artery narrowing are the common complications of ASO. CCTGA may manifest late in life, even in adulthood. Surgeries for associated lesions such as tricuspid regurgitation, subpulmonic stenosis, and ventricular septal defect may be performed. A doubleswitch operation that includes both the atrial and arterial switch operations constitutes anatomic correction for CCTGA. Imaging plays an important role in the evaluation of TGA, both before and after surgery, for helping define the anatomy, quantify hemodynamics, and evaluate complications. Transthoracic echocardiography is the first-line imaging modality for presurgical planning in children with TGA. MRI provides comprehensive morphologic and functional information, particularly in adults after surgery. CT is performed when MRI is contraindicated or expected to generate artifacts. The authors review the imaging appearances of TGA, with a focus on pre-and postsurgical imaging.

Research paper thumbnail of Radiological approach to cavitary lung lesions

Postgraduate Medical Journal, 2020

Cavitary lesions in the lung are not an uncommon imaging encounter and carry a broad differential... more Cavitary lesions in the lung are not an uncommon imaging encounter and carry a broad differential diagnosis that includes a wide range of pathological conditions from cancers, infections/inflammatory processes to traumatic and congenital lung abnormalities. In this review article, we describe a comprehensive approach for evaluation of cavitary lung lesions and discuss the differential diagnosis in the light of radiological findings.

Research paper thumbnail of A Rare Pulmonary-Systemic Connection: Levoatriocardinal Vein

Radiology: Cardiothoracic Imaging, 2020

Research paper thumbnail of Rare intrathoracic rib: Significance and associations in and adult

Lung India, 2020

© 2020 Indian Chest Society | Published by Wolters Kluwer Medknow This is an open access journal,... more © 2020 Indian Chest Society | Published by Wolters Kluwer Medknow This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. Access this article online Quick Response Code: Website: www.lungindia.com

Research paper thumbnail of Future Directions in Coronary CT Angiography: CT-Fractional Flow Reserve, Plaque Vulnerability, and Quantitative Plaque Assessment

Korean Circulation Journal, 2020

Coronary computed tomography angiography (CCTA) is a well-validated and noninvasive imaging modal... more Coronary computed tomography angiography (CCTA) is a well-validated and noninvasive imaging modality for the assessment of coronary artery disease (CAD) in patients with stable ischemic heart disease and acute coronary syndromes (ACSs). CCTA not only delineates the anatomy of the heart and coronary arteries in detail, but also allows for intra-and extraluminal imaging of coronary arteries. Emerging technologies have promoted new CCTA applications, resulting in a comprehensive assessment of coronary plaques and their clinical significance. The application of computational fluid dynamics to CCTA resulted in a robust tool for noninvasive assessment of coronary blood flow hemodynamics and determination of hemodynamically significant stenosis. Detailed evaluation of plaque morphology and identification of high-risk plaque features by CCTA have been confirmed as predictors of future outcomes, identifying patients at risk for ACSs. With quantitative coronary plaque assessment, the progression of the CAD or the response to therapy could be monitored by CCTA. The aim of this article is to review the future directions of emerging applications in CCTA, such as computed tomography (CT)-fractional flow reserve, imaging of vulnerable plaque features, and quantitative plaque imaging. We will also briefly discuss novel methods appearing in the coronary imaging scenario, such as machine learning, radiomics, and spectral CT.

Research paper thumbnail of MRI of the Pericardium

Research paper thumbnail of The Relationship of Pulmonary Artery Computed Tomography Obstruction Index Ratio, D-Dimer and Mean Platelet Volume Levels in Pulmonary Embolism

Turkiye Klinikleri Archives of Lung, 2017

Research paper thumbnail of Toraks difüzyon ağırlıklı görüntülemede “b değeri”

Tuberkuloz ve Toraks, 2015

Research paper thumbnail of Magnetic resonance imaging findings of two sisters with Van der Knaap leukoencephalopathy

The neuroradiology journal, 2015

Megalencephalic leukoencephalopathy with subcortical cysts, or Van der Knaap leukoencephalopathy,... more Megalencephalic leukoencephalopathy with subcortical cysts, or Van der Knaap leukoencephalopathy, is a rare disease which is characterised by macrocephaly and neurological disorders with autosomal recessive inheritance. Magnetic resonance imaging is very helpful for determining distinctive findings and distinguishing other diseases. We present the radiological findings of two sisters (aged 6 and 10 years) diagnosed with Van der Knaap leukoencephalopathy.

Research paper thumbnail of Morphometric measurements of the cranium in congenital bilateral blind males and females

Bosnian journal of basic medical sciences / Udruženje basičnih mediciniskih znanosti = Association of Basic Medical Sciences, 2013

Cranium dimensions differ according to racial, geopraphic, ethnic and nutritional factors. This s... more Cranium dimensions differ according to racial, geopraphic, ethnic and nutritional factors. This study will shed light on the question: "Is there a difference in the cranial distances measured between congenital bilateral blind people and healthy individuals?" Nine anthropometric measures were performed on the brain MRI midsagittally obtained from male and female congenital bilateral blinds. The anthropometric measures taken included the glabella-opisthocranion, nasion-dorsum sellae, dorsum sellae- opisthocranion, nasion-basion, nasion-opisthion, basion-opisthion, prosthion-basion, basion-vertex and the clival angle. In addition, the supratentorial and infratentorial areas were calculated. Glabella-opisthocranion, nasion-dorsum sellae, nasion-basion, prosthion-basion and clival angle were found to be smaller in the congenital bilateral blind females compared to the healthy group, but these results were not statistically significant. Whereas, other measures out of the basion...

Research paper thumbnail of Multiple tendon xanthomas in patient with heterozygous familial hypercholesterolaemia: sonographic and MRI findings

Research paper thumbnail of Silent ischemic pancreatitis following urosepsis

Journal of Experimental and Clinical Medicine, 2013

Pancreatic ischemia is an uncommon cause of acute pancreatitis. Ischemia with resultant pancreati... more Pancreatic ischemia is an uncommon cause of acute pancreatitis. Ischemia with resultant pancreatitis has been reported in vasculitis, atheroembolism, intraoperative hypotension, survivors of cardiac arrest and hemorrhagic shock. Ischemic acute pancreatitis is difficult to recognize clinically. In this report we present a 63 year old woman with painless ischemic pancreatitis following urosepsis. We suggest that if a critically ill patient is hypotensive for more than 24-48 hours, amylase levels must be monitored to establish ischemic acute pancreatitis (AP) even if the patient remains asymptomatic.

Research paper thumbnail of Bilateral TalamikInfarkt: Percheron Arteri Oklüzyonu

Nöro Psikiyatri Arşivi, 2013

Re cei ved/Ge liş ta ri hi: 04.12.2012 Ac cep ted/Ka bul ta ri hi: 28.12.2012 © Arc hi ves of Neu... more Re cei ved/Ge liş ta ri hi: 04.12.2012 Ac cep ted/Ka bul ta ri hi: 28.12.2012 © Arc hi ves of Neu ropsy chi atry, pub lis hed by Ga le nos Pub lis hing/ © Nö rop si ki yat ri Ar şi vi Der gi si, Ga le nos Ya yı ne vi ta ra f›n dan ba s›l m›fl t›r.

Research paper thumbnail of Mean platelet volume and D-dimer in patients with suspected deep venous thrombosis

Journal of Thrombosis and Thrombolysis, 2012

The aim of this retrospective study was to evaluate the diagnostic value of mean platelet volume ... more The aim of this retrospective study was to evaluate the diagnostic value of mean platelet volume (MPV) and D-dimer for acute deep venous thromboembolism (DVT). Two hundred and fifty six patients who presented to the emergency or cardiovascular surgery department with suspected lower limb DVT were retrospectively recruited. Plasma levels of MPV, platelet count, and D-dimer were obtained and duplex sonography examination was performed for all patients. Eighty four patients had acute DVT which was diagnosed by duplex ultrasonography. MPV was significantly higher in patients with DVT than in those without DVT (p \ 0.01). The mean MPV was 7.97 ± 17.8 and 7.58 ± 0.87 fL in patients with DVT and without DVT, respectively (p \ 0.01). D-dimer was significantly higher in patients with DVT (p \ 0.01). For all the patients, a positive MPV when the cutoff value was 7.3 fL, had 69.7 % sensitivity and 43.9 % specificity. D-dimer (with a cutoff value of 0.5 lg/mL) had 82.9 % sensitivity and 32.7 % specificity. In case of combination of MPV and D-dimer, the specificity exceeded (65.9 %) despite the reduction in sensitivity (59.2 %). Elevated MPV was found to be associated with acute DVT and high levels of MPV might increase the specificity of D-dimer for exclusion of DVT. Keywords D-dimer Á Doppler Á Deep venous thrombosis Á Mean platelet volume