Bahar Dehghan - Academia.edu (original) (raw)

Papers by Bahar Dehghan

Research paper thumbnail of A 14.5-Year-Old Boy with Coronary Obstruction after Kawasaki Disease: A Case Report

The Journal of Tehran University Heart Center

Kawasaki disease (KD) is a febrile vasculitis and is considered a leading cause of acquired coron... more Kawasaki disease (KD) is a febrile vasculitis and is considered a leading cause of acquired coronary artery disease in children. A clinically critical complication is the coronary artery aneurysm, which may progress and lead to coronary stenosis or even obstruction. Herein, we describe a 14.5-year-old boy with a history of KD at 6 months old, who developed multiple aneurysms along all the coronary branches. During the follow-up at the age of 14 years, the left coronary artery aneurysms regressed, while the aneurysm of the right coronary artery persisted and was complicated by obstruction at its proximal part, according to computed tomography angiography. However, the patient at the last follow-up was asymptomatic and well. The serious nature of KD coronary complications warrants follow-up visits. Since echocardiography alone may fail to reveal stenosis or obstruction, other adjunct follow-up imaging modalities such as conventional, computed tomography, and magnetic resonance angiogr...

Research paper thumbnail of Congenital Hypothyroidism; is There any Familial Component?

مجله دانشکده پزشکی اصفهان, 2009

Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates... more Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates. Recently, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. The aim of this study was to evaluate the abnormality of thyroid function tests in first degree relatives of CH neonates and compared it to normal population. Methods: From 2002-2007 thyroid function tests (T4 and TSH) of 194 randomly selected CH neonates borne in all 17 hospitals of the Isfahan, Iran and their first degree relatives were measured, and compared with thyroid function tests of first degree relatives of 350 normal neonates that randomly selected as sex, age and urban/rural status. Patients' mothers and control groups were also evaluated for TPO antibody. Statistical analysis was performed by SPSS (version 11.5; SPSS Inc., Chicago, IL) and Chi Square test used to compare two groups. Findings: Thyroid function tests was measured in the first de...

Research paper thumbnail of The Association of Helicobacter pylori Infection with Endothelial Dysfunction in Pediatric Patients

Archives of Pediatric Infectious Diseases, Oct 21, 2018

Objectives: The aim of this study was to evaluate endothelial dysfunction in pediatric patients w... more Objectives: The aim of this study was to evaluate endothelial dysfunction in pediatric patients with Helicobacter pylori infection. Methods: In a cross sectional study, 50 children between six and twelve years old were evaluated for Helicobacter pylori infection by a histopathologic specimen. C-reactive protein (CRP) and Interleukin-12 of all subjects was checked. Endothelial dysfunction was evaluated by echocardiography of brachial artery and through measuring flow mediated dilatation (FMD). Results: Mean of FMD level was significantly higher in children with H. pylori infection (P value: 0.04). Interlukin-12 (IL-12) was higher in children with H. pylori infection (P value: 0.04). Linear regression showed a positive association of Helicobacter pylori infection and endothelial dysfunction (beta = 0.3, P value = 0.08). Conclusions: Children with Helicobacter pylori infection have more endothelial dysfunction independent of IL-12.

Research paper thumbnail of Comparison of cost-effectiveness and postoperative outcome of device closure and open surgery closure techniques for treatment of patent ductus arteriosus

ARYA Atherosclerosis, 2014

Various devices have been recently employed for percutaneous closure of the patent ductus arterio... more Various devices have been recently employed for percutaneous closure of the patent ductus arteriosus (PDA). Although the high effectiveness of device closure techniques has been clearly determined, a few studies have focused on the cost-effectiveness and also postoperative complications of these procedures in comparison with open surgery. The present study aimed to evaluate the clinical outcome and cost-effectiveness of PDA occlusion by Amplatzer and coil device in comparisong with open surgery. In this cross-sectional study, a randomized sample of 201 patients aged 1 month to 16 years (105 patients with device closure and 96 patients with surgical closure) was selected. The ratio of total pulmonary blood flow to total systemic blood flow, the Qp/Qs ratio, was measured using a pulmonary artery catheter. The cost analysis included direct medical care costs associated with device implantation and open surgery, as well as professional fees. All costs were calculated in Iranian Rials an...

Research paper thumbnail of Comparison of cost-effectiveness and postoperative outcome of device closure and open surgery closure techniques for treatment of patent ductus arteriosus

ARYA Atherosclerosis, 2014

Various devices have been recently employed for percutaneous closure of the patent ductus arterio... more Various devices have been recently employed for percutaneous closure of the patent ductus arteriosus (PDA). Although the high effectiveness of device closure techniques has been clearly determined, a few studies have focused on the cost-effectiveness and also postoperative complications of these procedures in comparison with open surgery. The present study aimed to evaluate the clinical outcome and cost-effectiveness of PDA occlusion by Amplatzer and coil device in comparisong with open surgery. In this cross-sectional study, a randomized sample of 201 patients aged 1 month to 16 years (105 patients with device closure and 96 patients with surgical closure) was selected. The ratio of total pulmonary blood flow to total systemic blood flow, the Qp/Qs ratio, was measured using a pulmonary artery catheter. The cost analysis included direct medical care costs associated with device implantation and open surgery, as well as professional fees. All costs were calculated in Iranian Rials an...

Research paper thumbnail of A case series of pulmonary hypertension in small infants with atrial septal defect

ARYA Atherosclerosis, 2020

BACKGROUND Atrial septal defect (ASD) is one of the most common congenital heart defects (CHDs) w... more BACKGROUND Atrial septal defect (ASD) is one of the most common congenital heart defects (CHDs) with prevalence of 8% to 10% in children with CHD and incidence of 56 per 100000 live births. It is categorized according to the defect site in which the most common form is secundum ASD (ASD2) with the defect in the central part of the atrial septum. CASE REPORT In our case series, we evaluated five children aged under one year old with ASD2 and pulmonary hypertension (PH). All the patients were referred for surgical ASD closure. Their PH was improved and the size of right atrium (RA) and right ventricle (RV) became normal during the follow-up and one year after the surgery all of them had normal pulmonary artery pressure (PAP) with normal RA and RV size. CONCLUSION According to our study and those done by others, the prevalence of PH in infants with ASD is low, but when this combination is found without any other CHD, ASD closure should be considered.

Research paper thumbnail of title: Congenital Hypothyroidism (CH); thyroid function abnormalities among first-degree relatives of Iranian CH neonates *

Kamal Heidari****, Ali Sajadi*****, Masoomeh Dastanpour******, Ali Ajami*******, Silva Hovsepian ... more Kamal Heidari****, Ali Sajadi*****, Masoomeh Dastanpour******, Ali Ajami*******, Silva Hovsepian ********, Ashraf Aminoroaya********* Bahar Dehghan********** * MD, Full professor of pediatric endocrinology, Isfahan endocrinology and metabolism research center, Isfahan University of medical sciences, Isfahan, Iran. ** Last Year Medical Student, Isfahan Medical Students Research Committee, Isfahan University of medical sciences, Isfahan, Iran. *** MD, Full professor of endocrinology, Isfahan endocrine and metabolic research center, Isfahan University of medical sciences, Isfahan, Iran. **** MD, Executive of Isfahan Health Center, Isfahan University of medical sciences, Isfahan, Iran. ***** MD, Technical assistant director of Isfahan Health Center, Isfahan University of

Research paper thumbnail of Comparison of cost-effectiveness and postoperative outcome of device closure and open surgery closure techniques for treatment of patent ductus arteriosus

ARYA Atherosclerosis, 2014

BACKGROUND Various devices have been recently employed for percutaneous closure of the patent duc... more BACKGROUND Various devices have been recently employed for percutaneous closure of the patent ductus arteriosus (PDA). Although the high effectiveness of device closure techniques has been clearly determined, a few studies have focused on the cost-effectiveness and also postoperative complications of these procedures in comparison with open surgery. The present study aimed to evaluate the clinical outcome and cost-effectiveness of PDA occlusion by Amplatzer and coil device in comparisong with open surgery. METHODS In this cross-sectional study, a randomized sample of 201 patients aged 1 month to 16 years (105 patients with device closure and 96 patients with surgical closure) was selected. The ratio of total pulmonary blood flow to total systemic blood flow, the Qp/Qs ratio, was measured using a pulmonary artery catheter. The cost analysis included direct medical care costs associated with device implantation and open surgery, as well as professional fees. All costs were calculated ...

Research paper thumbnail of The efficacy and safety of using amplatzer for transcatheter closure of atrial septal defect in small children with less than 10 kg

ARYA Atherosclerosis, 2019

BACKGROUND Atrial septal defect (ASD) accounts for about 10% of congenital heart diseases (CHDs).... more BACKGROUND Atrial septal defect (ASD) accounts for about 10% of congenital heart diseases (CHDs). Self-closure of these defects in patients with defects less than 8 mm has been reported in several studies. In children, transcatheter closure of the ASD is suggested for asymptomatic patients older than two years and with weight > 15 kg. The purpose of this study was to show that transcatheter closure of ASD in small children with body weight less than 10 kg is an effective and safe method. METHODS Between July 2016 and September 2018, 35 children with body weight less than 10 kg underwent percutaneous closure of ASD using amplatzer. All patients had minimum defect size of 6 mm, pulmonary blood flow (Qp) to systemic blood flow (Qs) ratio above 1.5, right atrial and ventricular dilation, symptoms of delayed growth, and recurrent respiratory infections in their evaluation and had acceptable rims for intervention. Follow-up evaluations were done 1 day, 1 week, 1 month, 6 months, and ye...

Research paper thumbnail of Case Report: Acute Intracardiac Thrombosis in Children With Coronavirus Disease 2019 (COVID-19)

Frontiers in Pediatrics

We herein describe a case series of children with SARS-CoV-2 infection (COVID-19) complicated wit... more We herein describe a case series of children with SARS-CoV-2 infection (COVID-19) complicated with acute intracardiac thrombosis. The diagnosis of COVID-19 was confirmed through the reverse transcription-polymerase chain reaction (RT-PCR). Transthoracic echocardiography of patients revealed large intracardiac mobile masses resected successfully via cardiac surgery. The underlying mechanisms of this thrombus in the COVID-19 infection may be attributed to the hypercoagulation and inflammatory state of the disease incurred by the SARS-CoV-2 virus.

Research paper thumbnail of Evaluation of cardiac function in children after percutaneous closure of atrial septal defect using speckle tracking echocardiography

BACKGROUND Atrial septal defect (ASD) is among the most common congenital anomalies that its negl... more BACKGROUND Atrial septal defect (ASD) is among the most common congenital anomalies that its neglect may cause severe right ventricular (RV)-associated cardiac dysfunction. Percutaneous closure of ASD is an efficient technique used commonly worldwide. Varieties of techniques have been used to assess postoperative changes of cardiac function. The current study has aimed to assess outcomes of percutaneous ASD closure using two-dimensional speckle tracking echocardiography (2D-STE). METHODS This non-experimental research was conducted on 22 patients who volunteered for percutaneous ASD closure between 2016 and 2018. Cases were assessed three times including prior to percutaneous ASD closure, after 24 hours, and a month after procedure. Cases outcomes were assessed and compared during the time. RESULTS Strain rate in RV middle septal wall was significantly different (P < 0.050) between before and one month after the procedure. Comparison of indices post procedure and one month later ...

Research paper thumbnail of Association of Helicobacter pylori infection with psoriasis and lichen planus: prevalence and effect of eradication therapy

Research paper thumbnail of The commencement of congenital heart diseases registry in Isfahan, Iran: Methodology and design

BACKGROUND Reported prevalence of congenital heart diseases (CHDs) varies widely among studies wo... more BACKGROUND Reported prevalence of congenital heart diseases (CHDs) varies widely among studies worldwide. The incidence of CHD, total number of pediatric and adult grown-up congenital heart disease (GUCH), is not determined in Iran. Therefore, we have designed a system to register the information of patients with CHD for the first time in our country. METHODS CHD registry is a database in which the patients' data are collected by five pediatric cardiologists from three referral hospitals affiliated to Isfahan University of Medical Sciences, Isfahan, Iran, and five outpatient clinics. We enrolled patients with CHD either as new cases who were referred for evaluation of potential CHD or those who were being followed within the outpatient clinics and entered their whole information in a website specifically designed for it. All the information was collected from checklist by those pediatric cardiologists RESULTS From April 2017 to April 2020, after developing the forms and website,...

Research paper thumbnail of Early Results of the Persian Registry of Cardiovascular Disease/Congenital Heart Disease (PROVE/CHD) in Isfahan

Background: In 2016, a prospective registry for pediatric patients with congenital heart disease ... more Background: In 2016, a prospective registry for pediatric patients with congenital heart disease (CHD) was established in Isfahan, Iran. Data on pediatric CHD in Iran are scant; accordingly, we aimed to report the early results of the Persian Registry Of cardioVascular diseasE (PROVE/CHD) Registry in Isfahan. Methods: All patients with CHD and associated defects diagnosed by pediatric cardiologists were assessed via echocardiography for inclusion in the present study between late 2016 and August 2019. The participants’ sociodemographic characteristics, maternal history, birth history, medical history, current clinical presentations in the clinic or hospital, paraclinical data, cardiac diagnoses based on the International Classification of Diseases, 10th Revision (ICD-10), disease management plans, and medications were entered into a questionnaire by the subjects’ parents/legal custodians and physicians and then transferred to the PROVE/CHD Registry. Results: The PROVE/CHD registry e...

Research paper thumbnail of Congenital Hypothyroidism; is There any Familial Component?

Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates... more Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates. Recently, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. The aim of this study was to evaluate the ...

Research paper thumbnail of Right Atrial Thrombus in a COVID-19 Child Treated Through Cardiac Surgery

Frontiers in Cardiovascular Medicine

Research paper thumbnail of Three Probable Pediatrics COVID-19 Cases with Kawasaki-Like Disease: A Case Series with Fallow-Up

Archives of Pediatric Infectious Diseases

: The first case of Kawasaki-like disease in children infected with COVID-19 was reported in a pr... more : The first case of Kawasaki-like disease in children infected with COVID-19 was reported in a preprint case report. In the present case series, three pediatric probable cases with COVID-19, who presented signs and symptoms of Kawasaki-like syndrome, and their three-month follow-up are provided.

Research paper thumbnail of Clinical outcome of right ventricular outflow tract stenting versus Blalock-Taussig shunt in Tetralogy of Fallot: A systematic review and meta-analysis

Current Problems in Cardiology

Research paper thumbnail of Nonpharmacologic treatments alone are enough to prevent the neurally mediated syncope: A 3 years follow-up study

International Journal of Preventive Medicine

Research paper thumbnail of The importance of mean platelet volume in predicting cardiac mechanics parameters and carotid-intima media thickness in children with end stage renal disease and comparison with healthy children

Therapeutic Apheresis and Dialysis

Research paper thumbnail of A 14.5-Year-Old Boy with Coronary Obstruction after Kawasaki Disease: A Case Report

The Journal of Tehran University Heart Center

Kawasaki disease (KD) is a febrile vasculitis and is considered a leading cause of acquired coron... more Kawasaki disease (KD) is a febrile vasculitis and is considered a leading cause of acquired coronary artery disease in children. A clinically critical complication is the coronary artery aneurysm, which may progress and lead to coronary stenosis or even obstruction. Herein, we describe a 14.5-year-old boy with a history of KD at 6 months old, who developed multiple aneurysms along all the coronary branches. During the follow-up at the age of 14 years, the left coronary artery aneurysms regressed, while the aneurysm of the right coronary artery persisted and was complicated by obstruction at its proximal part, according to computed tomography angiography. However, the patient at the last follow-up was asymptomatic and well. The serious nature of KD coronary complications warrants follow-up visits. Since echocardiography alone may fail to reveal stenosis or obstruction, other adjunct follow-up imaging modalities such as conventional, computed tomography, and magnetic resonance angiogr...

Research paper thumbnail of Congenital Hypothyroidism; is There any Familial Component?

مجله دانشکده پزشکی اصفهان, 2009

Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates... more Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates. Recently, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. The aim of this study was to evaluate the abnormality of thyroid function tests in first degree relatives of CH neonates and compared it to normal population. Methods: From 2002-2007 thyroid function tests (T4 and TSH) of 194 randomly selected CH neonates borne in all 17 hospitals of the Isfahan, Iran and their first degree relatives were measured, and compared with thyroid function tests of first degree relatives of 350 normal neonates that randomly selected as sex, age and urban/rural status. Patients' mothers and control groups were also evaluated for TPO antibody. Statistical analysis was performed by SPSS (version 11.5; SPSS Inc., Chicago, IL) and Chi Square test used to compare two groups. Findings: Thyroid function tests was measured in the first de...

Research paper thumbnail of The Association of Helicobacter pylori Infection with Endothelial Dysfunction in Pediatric Patients

Archives of Pediatric Infectious Diseases, Oct 21, 2018

Objectives: The aim of this study was to evaluate endothelial dysfunction in pediatric patients w... more Objectives: The aim of this study was to evaluate endothelial dysfunction in pediatric patients with Helicobacter pylori infection. Methods: In a cross sectional study, 50 children between six and twelve years old were evaluated for Helicobacter pylori infection by a histopathologic specimen. C-reactive protein (CRP) and Interleukin-12 of all subjects was checked. Endothelial dysfunction was evaluated by echocardiography of brachial artery and through measuring flow mediated dilatation (FMD). Results: Mean of FMD level was significantly higher in children with H. pylori infection (P value: 0.04). Interlukin-12 (IL-12) was higher in children with H. pylori infection (P value: 0.04). Linear regression showed a positive association of Helicobacter pylori infection and endothelial dysfunction (beta = 0.3, P value = 0.08). Conclusions: Children with Helicobacter pylori infection have more endothelial dysfunction independent of IL-12.

Research paper thumbnail of Comparison of cost-effectiveness and postoperative outcome of device closure and open surgery closure techniques for treatment of patent ductus arteriosus

ARYA Atherosclerosis, 2014

Various devices have been recently employed for percutaneous closure of the patent ductus arterio... more Various devices have been recently employed for percutaneous closure of the patent ductus arteriosus (PDA). Although the high effectiveness of device closure techniques has been clearly determined, a few studies have focused on the cost-effectiveness and also postoperative complications of these procedures in comparison with open surgery. The present study aimed to evaluate the clinical outcome and cost-effectiveness of PDA occlusion by Amplatzer and coil device in comparisong with open surgery. In this cross-sectional study, a randomized sample of 201 patients aged 1 month to 16 years (105 patients with device closure and 96 patients with surgical closure) was selected. The ratio of total pulmonary blood flow to total systemic blood flow, the Qp/Qs ratio, was measured using a pulmonary artery catheter. The cost analysis included direct medical care costs associated with device implantation and open surgery, as well as professional fees. All costs were calculated in Iranian Rials an...

Research paper thumbnail of Comparison of cost-effectiveness and postoperative outcome of device closure and open surgery closure techniques for treatment of patent ductus arteriosus

ARYA Atherosclerosis, 2014

Various devices have been recently employed for percutaneous closure of the patent ductus arterio... more Various devices have been recently employed for percutaneous closure of the patent ductus arteriosus (PDA). Although the high effectiveness of device closure techniques has been clearly determined, a few studies have focused on the cost-effectiveness and also postoperative complications of these procedures in comparison with open surgery. The present study aimed to evaluate the clinical outcome and cost-effectiveness of PDA occlusion by Amplatzer and coil device in comparisong with open surgery. In this cross-sectional study, a randomized sample of 201 patients aged 1 month to 16 years (105 patients with device closure and 96 patients with surgical closure) was selected. The ratio of total pulmonary blood flow to total systemic blood flow, the Qp/Qs ratio, was measured using a pulmonary artery catheter. The cost analysis included direct medical care costs associated with device implantation and open surgery, as well as professional fees. All costs were calculated in Iranian Rials an...

Research paper thumbnail of A case series of pulmonary hypertension in small infants with atrial septal defect

ARYA Atherosclerosis, 2020

BACKGROUND Atrial septal defect (ASD) is one of the most common congenital heart defects (CHDs) w... more BACKGROUND Atrial septal defect (ASD) is one of the most common congenital heart defects (CHDs) with prevalence of 8% to 10% in children with CHD and incidence of 56 per 100000 live births. It is categorized according to the defect site in which the most common form is secundum ASD (ASD2) with the defect in the central part of the atrial septum. CASE REPORT In our case series, we evaluated five children aged under one year old with ASD2 and pulmonary hypertension (PH). All the patients were referred for surgical ASD closure. Their PH was improved and the size of right atrium (RA) and right ventricle (RV) became normal during the follow-up and one year after the surgery all of them had normal pulmonary artery pressure (PAP) with normal RA and RV size. CONCLUSION According to our study and those done by others, the prevalence of PH in infants with ASD is low, but when this combination is found without any other CHD, ASD closure should be considered.

Research paper thumbnail of title: Congenital Hypothyroidism (CH); thyroid function abnormalities among first-degree relatives of Iranian CH neonates *

Kamal Heidari****, Ali Sajadi*****, Masoomeh Dastanpour******, Ali Ajami*******, Silva Hovsepian ... more Kamal Heidari****, Ali Sajadi*****, Masoomeh Dastanpour******, Ali Ajami*******, Silva Hovsepian ********, Ashraf Aminoroaya********* Bahar Dehghan********** * MD, Full professor of pediatric endocrinology, Isfahan endocrinology and metabolism research center, Isfahan University of medical sciences, Isfahan, Iran. ** Last Year Medical Student, Isfahan Medical Students Research Committee, Isfahan University of medical sciences, Isfahan, Iran. *** MD, Full professor of endocrinology, Isfahan endocrine and metabolic research center, Isfahan University of medical sciences, Isfahan, Iran. **** MD, Executive of Isfahan Health Center, Isfahan University of medical sciences, Isfahan, Iran. ***** MD, Technical assistant director of Isfahan Health Center, Isfahan University of

Research paper thumbnail of Comparison of cost-effectiveness and postoperative outcome of device closure and open surgery closure techniques for treatment of patent ductus arteriosus

ARYA Atherosclerosis, 2014

BACKGROUND Various devices have been recently employed for percutaneous closure of the patent duc... more BACKGROUND Various devices have been recently employed for percutaneous closure of the patent ductus arteriosus (PDA). Although the high effectiveness of device closure techniques has been clearly determined, a few studies have focused on the cost-effectiveness and also postoperative complications of these procedures in comparison with open surgery. The present study aimed to evaluate the clinical outcome and cost-effectiveness of PDA occlusion by Amplatzer and coil device in comparisong with open surgery. METHODS In this cross-sectional study, a randomized sample of 201 patients aged 1 month to 16 years (105 patients with device closure and 96 patients with surgical closure) was selected. The ratio of total pulmonary blood flow to total systemic blood flow, the Qp/Qs ratio, was measured using a pulmonary artery catheter. The cost analysis included direct medical care costs associated with device implantation and open surgery, as well as professional fees. All costs were calculated ...

Research paper thumbnail of The efficacy and safety of using amplatzer for transcatheter closure of atrial septal defect in small children with less than 10 kg

ARYA Atherosclerosis, 2019

BACKGROUND Atrial septal defect (ASD) accounts for about 10% of congenital heart diseases (CHDs).... more BACKGROUND Atrial septal defect (ASD) accounts for about 10% of congenital heart diseases (CHDs). Self-closure of these defects in patients with defects less than 8 mm has been reported in several studies. In children, transcatheter closure of the ASD is suggested for asymptomatic patients older than two years and with weight > 15 kg. The purpose of this study was to show that transcatheter closure of ASD in small children with body weight less than 10 kg is an effective and safe method. METHODS Between July 2016 and September 2018, 35 children with body weight less than 10 kg underwent percutaneous closure of ASD using amplatzer. All patients had minimum defect size of 6 mm, pulmonary blood flow (Qp) to systemic blood flow (Qs) ratio above 1.5, right atrial and ventricular dilation, symptoms of delayed growth, and recurrent respiratory infections in their evaluation and had acceptable rims for intervention. Follow-up evaluations were done 1 day, 1 week, 1 month, 6 months, and ye...

Research paper thumbnail of Case Report: Acute Intracardiac Thrombosis in Children With Coronavirus Disease 2019 (COVID-19)

Frontiers in Pediatrics

We herein describe a case series of children with SARS-CoV-2 infection (COVID-19) complicated wit... more We herein describe a case series of children with SARS-CoV-2 infection (COVID-19) complicated with acute intracardiac thrombosis. The diagnosis of COVID-19 was confirmed through the reverse transcription-polymerase chain reaction (RT-PCR). Transthoracic echocardiography of patients revealed large intracardiac mobile masses resected successfully via cardiac surgery. The underlying mechanisms of this thrombus in the COVID-19 infection may be attributed to the hypercoagulation and inflammatory state of the disease incurred by the SARS-CoV-2 virus.

Research paper thumbnail of Evaluation of cardiac function in children after percutaneous closure of atrial septal defect using speckle tracking echocardiography

BACKGROUND Atrial septal defect (ASD) is among the most common congenital anomalies that its negl... more BACKGROUND Atrial septal defect (ASD) is among the most common congenital anomalies that its neglect may cause severe right ventricular (RV)-associated cardiac dysfunction. Percutaneous closure of ASD is an efficient technique used commonly worldwide. Varieties of techniques have been used to assess postoperative changes of cardiac function. The current study has aimed to assess outcomes of percutaneous ASD closure using two-dimensional speckle tracking echocardiography (2D-STE). METHODS This non-experimental research was conducted on 22 patients who volunteered for percutaneous ASD closure between 2016 and 2018. Cases were assessed three times including prior to percutaneous ASD closure, after 24 hours, and a month after procedure. Cases outcomes were assessed and compared during the time. RESULTS Strain rate in RV middle septal wall was significantly different (P < 0.050) between before and one month after the procedure. Comparison of indices post procedure and one month later ...

Research paper thumbnail of Association of Helicobacter pylori infection with psoriasis and lichen planus: prevalence and effect of eradication therapy

Research paper thumbnail of The commencement of congenital heart diseases registry in Isfahan, Iran: Methodology and design

BACKGROUND Reported prevalence of congenital heart diseases (CHDs) varies widely among studies wo... more BACKGROUND Reported prevalence of congenital heart diseases (CHDs) varies widely among studies worldwide. The incidence of CHD, total number of pediatric and adult grown-up congenital heart disease (GUCH), is not determined in Iran. Therefore, we have designed a system to register the information of patients with CHD for the first time in our country. METHODS CHD registry is a database in which the patients' data are collected by five pediatric cardiologists from three referral hospitals affiliated to Isfahan University of Medical Sciences, Isfahan, Iran, and five outpatient clinics. We enrolled patients with CHD either as new cases who were referred for evaluation of potential CHD or those who were being followed within the outpatient clinics and entered their whole information in a website specifically designed for it. All the information was collected from checklist by those pediatric cardiologists RESULTS From April 2017 to April 2020, after developing the forms and website,...

Research paper thumbnail of Early Results of the Persian Registry of Cardiovascular Disease/Congenital Heart Disease (PROVE/CHD) in Isfahan

Background: In 2016, a prospective registry for pediatric patients with congenital heart disease ... more Background: In 2016, a prospective registry for pediatric patients with congenital heart disease (CHD) was established in Isfahan, Iran. Data on pediatric CHD in Iran are scant; accordingly, we aimed to report the early results of the Persian Registry Of cardioVascular diseasE (PROVE/CHD) Registry in Isfahan. Methods: All patients with CHD and associated defects diagnosed by pediatric cardiologists were assessed via echocardiography for inclusion in the present study between late 2016 and August 2019. The participants’ sociodemographic characteristics, maternal history, birth history, medical history, current clinical presentations in the clinic or hospital, paraclinical data, cardiac diagnoses based on the International Classification of Diseases, 10th Revision (ICD-10), disease management plans, and medications were entered into a questionnaire by the subjects’ parents/legal custodians and physicians and then transferred to the PROVE/CHD Registry. Results: The PROVE/CHD registry e...

Research paper thumbnail of Congenital Hypothyroidism; is There any Familial Component?

Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates... more Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates. Recently, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. The aim of this study was to evaluate the ...

Research paper thumbnail of Right Atrial Thrombus in a COVID-19 Child Treated Through Cardiac Surgery

Frontiers in Cardiovascular Medicine

Research paper thumbnail of Three Probable Pediatrics COVID-19 Cases with Kawasaki-Like Disease: A Case Series with Fallow-Up

Archives of Pediatric Infectious Diseases

: The first case of Kawasaki-like disease in children infected with COVID-19 was reported in a pr... more : The first case of Kawasaki-like disease in children infected with COVID-19 was reported in a preprint case report. In the present case series, three pediatric probable cases with COVID-19, who presented signs and symptoms of Kawasaki-like syndrome, and their three-month follow-up are provided.

Research paper thumbnail of Clinical outcome of right ventricular outflow tract stenting versus Blalock-Taussig shunt in Tetralogy of Fallot: A systematic review and meta-analysis

Current Problems in Cardiology

Research paper thumbnail of Nonpharmacologic treatments alone are enough to prevent the neurally mediated syncope: A 3 years follow-up study

International Journal of Preventive Medicine

Research paper thumbnail of The importance of mean platelet volume in predicting cardiac mechanics parameters and carotid-intima media thickness in children with end stage renal disease and comparison with healthy children

Therapeutic Apheresis and Dialysis