Bruna Santos - Academia.edu (original) (raw)

Papers by Bruna Santos

International journal of molecular sciences, 2016

Vernonia polyanthes Less. (Asteraceae), popularly known as "assa-peixe", is a plant spe... more Vernonia polyanthes Less. (Asteraceae), popularly known as "assa-peixe", is a plant species used in Brazilian traditional medicine for the treatment of cutaneous damage, cicatrization, inflammation, and rheumatism. Based on these ethnopharmacological findings, the current study evaluated the topical anti-inflammatory effects of the hexane (HEVP) and ethyl acetate (EAEVP) extracts from V. polyanthes leaves in experimental models of skin inflammation. Chemical characterization was carried out by HPLC-UV/DAD analysis. Anti-inflammatory activity was evaluated using Croton oil-, arachidonic acid (AA)-, phenol-, ethyl phenylpropiolate (EPP)-, and capsaicin-induced ear edema models in mice. Histopathological evaluation and measurements of myeloperoxidase (MPO) and N-acetyl-β-d-glucosaminidase (NAG) enzymes were also performed. Rutin, luteolin, and apigenin were identified in EAEVP. Topically applied HEVP and EAEVP significantly (p < 0.05, p < 0.01 or p < 0.001) reduced e...

Early Years

ABSTRACT This article aims to discuss the quality of early childhood education and care in Brazil... more ABSTRACT This article aims to discuss the quality of early childhood education and care in Brazil and the process of infants’ and toddlers’ Inserimento to daycare. The theoretical framework of our arguments is based on the notion of quality of child education as a negotiated concept, and by the Italian concept of Inserimento. The methodology is based on the Mosaic Approach, a participative method to listen to young children. As part of the methodology, we participated in the inserimento process in five municipalities in southeastern Brazil, from 2016 and 2020. Data analysis was based on the pedagogy of listening and on studies on gender and racial relationships. The results show how laws, normative documents, family expectations, planning and routine of childhood education, available toys, space, babies, families, and professionals creates a complex mosaic of discourses about what constitutes the quality of childhood education in the babies' first days in daycare centers.

Tobacco, smoking control and health educ., 2020

Background: Prior studies have found that smokers with ST-segment elevation myocardial infarction... more Background: Prior studies have found that smokers with ST-segment elevation myocardial infarction (STEMI) are younger, have fewer coexisting high-features and lower mortality than nonsmokers. Objectives: To evaluate the relationship between cigarette smoking status and in-hospital outcomes of patients treated with STEMI at a tertiary hospital. Methods: Prospective cohort study of a single center. Patients admitted with STEMI between September 2016 and September 2019 were included. Smoking status was categorized as never-smokers, current smokers and former smokers. Clinical characteristics, length of stay, all-cause mortality and major cardiovascular events (MACE, defined as the composite of total mortality, re-infarction, stroke and cardiac arrest) during the in-hospital period were evaluated. Chi-square test, ANOVA and Tukey test, and the Kruskal-Wallis H test were used, as appropriate. P Results: Of the 230 patients hospitalized with STEMI in the period, 92 (40%) were currently smoking and 63 (27.3%) were former smokers. Current smokers (57.2±11.4 years) were younger than never-smokers (63.7±11.4 years) (p = 0.001) and former smokers (64.8±9.6 years) (p Conclusion: Compared to never-smokers and former smokers, current smoking is associated with the occurrence of STEMI at a younger age and with similar in-hospital mortality.

RESUMO: Este artigo analisa o sufixo nominal-pe muito produtivo na língua Kuikuro, umas das varia... more RESUMO: Este artigo analisa o sufixo nominal-pe muito produtivo na língua Kuikuro, umas das variantes do Karib alto-xinguano. Há descrições deste mesmo sufixo para outras línguas da família karib, tanto setentrionais como meridionais. Trata-se de um morfema gramatical com o valor temporal de 'passado' e restrito a Nomes, inclusive argumentos sentenciais cujo verbo apresenta a flexão de Aspecto Pontual. Na primeira parte, descrevemos o comportamento de-pe, em Kuikuro, com seus ambientes de ocorrência e restrições. A segunda parte é dedicada a uma comparação com dados e análises de outras línguas karib (Ikpeng , Tiriyó, Hixkaryâna e Ingarikó) para o mesmo morfema, quase sempre glosado como Tempo nominal. Na terceira parte, expandimos o sentido de-pe para a expressão de relações temporais complexas e sua articulação com a flexão aspectual e a semântica do verbo principal. Na última parte, apresentamos uma representação formal, considerando-pe como núcleo da projeção T na cartog...

Resumo: Objetiva analisar as formas de utilização de brinquedos como instrumentos terapêuticos e ... more Resumo: Objetiva analisar as formas de utilização de brinquedos como instrumentos terapêuticos e coadjuvantes ao tratamento da fisioterapia respiratória aplicada à pediatria. Método: revisão sistemática conduzida nas fontes eletrônicas Pubmed/Medline, LILACS e SciELO em maio de 2017 utilizando-se descritores (Mesh e Decs) e palavras-chave específicas para a temática investigada. Foram incluídos os estudos, Guidelines e revisões que referenciaram o uso de brinquedos como instrumentos terapêuticos durante o atendimento de fisioterapia respiratória na faixa etária pediátrica, analisados por 03 avaliadores independentes. Resultados: identificou-se 563 títulos, dos quais 08 elegíveis, sendo 05 publicados nos últimos 10 anos. Constatou-se o uso frequente de brinquedos de sopro simples (cata-vento, bolinha de sabão e de isopor) como dispositivos educativos para o controle respiratório, além da utilização do vídeo game, o qual apresentou benefícios ao ser empregado como alternativa de terap...

Construction and Building Materials, 2022

Objective: To describe how children respond to oral anticoagulation with warfarin and which facto... more Objective: To describe how children respond to oral anticoagulation with warfarin and which factors are related to this process and to identify risk factors for the occurrence of thrombotic events in childhood. Methodology: A retrospective descriptive study was conducted in a hospital in south of Brazil including all patients ≤18 years old for whom warfarin was prescribed between January 2014 and September 2015. Medical records of the institution were used for data collection. Results: 32 patients were included during the study period. The major risk factor identified was the use of central venous catheters (87, 1% of patients). Patients <1 years old needed longer time and required a higher dose of warfarin for anticoagulation. Patients with short bowel syndrome and who used total parenteral nutrition required a higher dose to achieve and maintain the INR (International Normalized Ratio) on target. All patients presented more INRs below the recommended range than in the range or ...

O artigo aborda as relacoes dos valores organizacionais perante os aspectos do individuo, do grup... more O artigo aborda as relacoes dos valores organizacionais perante os aspectos do individuo, do grupo e da organizacao. Apresenta esses valores repercutem sobre as crencas e as atitudes do individuo, o que da para a organizacao uma determinada identidade. Tambem apresenta os aspectos relativos a intencao de rotatividade demonstrando que nao e uma causa, mas sim o efeito de algumas variaveis internas e externas. O objetivo principal deste estudo foi investigar as relacoes existentes entre valores organizacionais e a intencao de rotatividade. O estudo foi desenvolvido com 171 empregados de duas organizacoes do ramo alimenticio de Uberlândia, MG, que responderam ao Inventario de Perfis de Valores Organizacionais, Intencao de Rotatividade e a um questionario de dados socio-demograficos. Resultados revelaram que existe correlacao negativa entre os tipos de valores e a intencao de rotatividade, exceto com o tipo de valor de tradicao. Os tipos de valores encontrados nas duas empresas foram si...

This paper is part of a more comprehensive research developed by the authors at Universidade Fede... more This paper is part of a more comprehensive research developed by the authors at Universidade Federal Fluminense and entitled “Housing, plan, city: the housing issue in the city of Niteroi and the process for the master plan (1960 – 1975)”. The above research aims to analyse the origin and development of the favelas of Niteroi-RJ (Brazil) in several dimensions, including how the housing situation occurs in the city planning process. In the case of this paper, it was considered the Master Plan elaborated by Wit-Olaf Prochnik’s office (1975-1977) that was preceded by large data collection and prospections that were base for an extensive list of proposals and projects. The purpose of this paper was to discuss two issues that represented, somehow, contradictory aspects related to the plan structured by the planning office. The first issue comes from the fact that it occurred an intensification of favela growth in the city of Niteroi, especially in the 1960s and the 1970s, along with the ...

A pesquisa e um estudo de caso aplicado ao bairro Atalaia no municipio de Aracaju-SE, justificand... more A pesquisa e um estudo de caso aplicado ao bairro Atalaia no municipio de Aracaju-SE, justificando o interesse mediante intensificacao do processo de verticalizacao. Configura-se como um bairro que vem registrando expressivo adensamento urbano, fato que se reflete no aumento do numero de construcoes e reducao da vegetacao, dando lugar a superficies de concreto. A escala temporal considerada amostral, pelos anos de 1984-2008-2015, tendo sido adotado como metodo de analise a Teoria e Clima Urbano de Monteiro, com foco no Conforto Termico, englobando as componentes termodinâmicas em suas relacoes. Os procedimentos adotados para o desenvolvimento da investigacao foram aerofotografias e imagens satelites fornecidas pelo INPE e USGS/EROS. Pretendeu-se avaliar a expansao da malha urbana da area em estudo, a retracao ou expansao da cobertura vegetal e albedo. De acordo com os dados mapeados, verifica-se um aumento da temperatura associado ao aumento da malha urbana, a diminuicao das areas v...

Studies in health technology and informatics, 2016

The present study aims to validate 15 terms and definitions for submission to the International C... more The present study aims to validate 15 terms and definitions for submission to the International Classification for Nursing Practice ICNP®. The terms were extracted from 148,299 narratives of the evolution of nursing care, free texts from Electronic Health Records, in a Brazilian university hospital. These terms were mapped with ICNP® 2013 for identifying differences, similarities and nonexistent terms. Definitions were made for the 15 most frequent nonexistent terms. Five Brazilian experts evaluated the settings through the Content Validity Index (CVI). Validation by 68 clinical practice experts is in progress. 2,638 different terms have been identified. After mapping and analysis, 15 terms were selected. Despite the importance of experts' assessment, the terminology is used by nurses in their daily practice. The classification of concepts is essential for the development of standards for Electronic Health Records.

It is largely accepted that the genetic susceptibility threshold is critical for Juvenile Myoclon... more It is largely accepted that the genetic susceptibility threshold is critical for Juvenile Myoclonic Epilepsy (JME) onset and probably reflects the simultaneous involvement of multiple genes with minor effect interacting with environment factors. The NPSR1 encoding gene became a high-ranking candidate for epilepsy susceptibility, specifically considering a recent report of the proconvulsive effects of NPS in mice and that gain-of-function NPSR1 polymorphisms were consistently associated with some epilepsy comorbidities, including sleep and anxiety. This case/control study was designed to investigate whether rs324981, rs2530547 and rs727162 NPSR1 polymorphisms are associated with JME in the Brazilian population. The polymorphisms were genotyped in 97 JME patients and 193 control subjects by qPCR using TaqMan® SNP Genotyping Assays. Descriptive and statistical analyses were performed using SNPstats software. No significant differences were observed in the genotypic and allelic frequenc...

Holzforschung, 2021

Lignocellulosic biomass represents a suitable feedstock for production of biofuels and bioproduct... more Lignocellulosic biomass represents a suitable feedstock for production of biofuels and bioproducts. Its chemical composition depends on many aspects (e.g. plant source, pre-processing) and it has impact on productivity of industrial bioprocesses. Numerous methodologies can be applied for biomass characterisation, with acid hydrolysis being a particularly relevant step. This study intended to assess the most suitable procedures for acid hydrolysis, taking Eucalyptus globulus bark as a case study. For that purpose, variation of temperature (90–120 °C) was evaluated over time (0–5 h), through monosaccharides and oligosaccharides contents and degradation. For glucose, the optimal conditions were 100 °C for 2.5 h, reaching a content of 48.6 wt.%. For xylose, the highest content (15.2 wt.%) was achieved at 90 °C for 2 h, or 120 °C for 0.5 h. Maximum concentrations of mannose and galactose (1.0 and 1.7 wt.%, respectively) were achieved at 90 and 100 °C (2–3.5 h) or at 120 °C (0.5–1 h). The...

Journal of Equine Veterinary Science, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

International Journal of Molecular Sciences, 2020

Background: Inoculation with Gluconacetobacter diazotrophicus has shown to influence root develop... more Background: Inoculation with Gluconacetobacter diazotrophicus has shown to influence root development in red rice plants, and more recently, the induced systemic tolerance (IST) response to drought was also demonstrated. The goal of this study was to evaluate the inoculation effect of G. diazotrophicus strain Pal5 on the amelioration of drought stress and root development in red rice (Oryza sativa L.). Methods: The experimental treatments consist of red rice plants inoculated with and without strain Pal5 in presence and absence of water restriction. Physiological, biochemical, and molecular analyses of plant roots were carried out, along with measurements of growth and biochemical components. Results: The plants showed a positive response to the bacterial inoculation, with root growth promotion and induction of tolerance to drought. An increase in the root area and higher levels of osmoprotectant solutes were observed in roots. Bacterial inoculation increased the drought tolerance a...

Veterinary Record, 2020

BackgroundIntraperitoneal administration of ceftriaxone maintains therapeutic abdominal concentra... more BackgroundIntraperitoneal administration of ceftriaxone maintains therapeutic abdominal concentrations for 24 hours in healthy horses. Therefore, it is a possible treatment for septic peritonitis. The aim of this study was to evaluate the efficacy of ceftriaxone as an adjuvant treatment in horses with septic peritonitis.MethodsTwenty-six horses with clinical signs, sonography and/or laboratory findings of septic peritonitis were included. Peritoneal fluid was collected for microbiological culture and in vitro microbial sensitivity profile assessment. Daily intraperitoneal administration of ceftriaxone (25 mg/kg) was initiated with supportive and systemic antimicrobial treatment. The animals were divided into three groups: group 1—gastrointestinal tract injuries and abdominal surgery (excluding perforations/ruptures); group 2—not related to changes in the gastrointestinal tract; group 3—secondary to intestinal rupture and/or faeces contamination.ResultsThe mean success rate of the tr...