C. Perniciaro - Academia.edu (original) (raw)

Papers by C. Perniciaro

Journal of the American Academy of Dermatology, 1994

The American Journal of Dermatopathology, 1999

The American Journal of Dermatopathology, 1997

Cutis, 1996

Familial cases of Kaposi's sarcoma are exceedingly rare. We identified an 85-year-old man wit... more Familial cases of Kaposi's sarcoma are exceedingly rare. We identified an 85-year-old man with Kaposi's sarcoma. Multiple lesions were present on the feet. Previously, the man's 84-year-old sister presented with similar lesions on the lower extremity. Both siblings were lifelong residents of the United States and were of English/German descent. Neither had risk factors for infection with human immunodeficiency virus (HIV). On histologic examination, lesions in both patients demonstrated vascular slits, hemorrhage, and dense aggregates of spindle cells within the dermis.

Acta dermato-venereologica, 1997

Acta dermato-venereologica, 1993

Two women with vulvodynia are described. In one patient, severe chronic vulvodynia developed seco... more Two women with vulvodynia are described. In one patient, severe chronic vulvodynia developed secondary to contact dermatitis. Patch-testing confirmed the offending allergens. A second patient with vulvodynia was severely dermatographic. Evaluation of patients with vulvodynia should include an appropriate medical history and diagnostic studies to exclude contact dermatitis and dermatographism. Effective treatment for these disorders may lead to dramatic relief of symptoms.

Cardiovascular surgery (London, England), 1993

Persistent postoperative incisional pain after aortocoronary bypass surgery was reported by a pat... more Persistent postoperative incisional pain after aortocoronary bypass surgery was reported by a patient in whom allergies to metals contained in the stainless steel suture used for sternal closure were confirmed by patch testing. The symptoms resolved promptly after the sutures were removed.

Cutis, 1994

Five cases of chilblain lupus erythematosus were retrospectively reviewed regarding their clinica... more Five cases of chilblain lupus erythematosus were retrospectively reviewed regarding their clinical, histopathologic, serologic, and immunofluorescence findings. Ages at onset of chilblain lupus erythematosus varied from 26 to 73 years, with a female-to-male ratio of 3:2. Since other entities can be confused with this disorder, we propose the following diagnostic criteria. The two major criteria are skin lesions in acral locations induced by exposure to cold or a drop in temperature, and evidence of lupus erythematosus in the skin lesions by results of histopathologic examination or direct immunofluorescence study. The three minor criteria are coexistence of systemic lupus erythematosus or other skin lesions of discoid lupus erythematosus, response to anti-lupus erythematosus therapy, and negative results of cryoglobulin and cold agglutinin studies. We conclude that chilblain lupus erythematosus can be diagnosed and treated. Discoid lupus erythematosus lesions respond more quickly to...

Dermatologic clinics, 1995

Gardner's syndrome is an autosomal dominant genodermatosis. Familial polyposis of the colon, ... more Gardner's syndrome is an autosomal dominant genodermatosis. Familial polyposis of the colon, osteomas, and cutaneous epidermoid cysts are characteristic features. Colon cancer will develop in all affected individuals unless prophylactic colectomy is performed. The follow-up and management of patients with Gardner's syndrome require a coordinated effort by physicians with expertise in gastroenterology, general surgery, oral surgery, radiology, endocrinology, neurology, ophthalmology, and dermatology. Genetic and psychological counseling should also be available for these patients.

Journal of the American Academy of Dermatology, 1984

In a series of nineteen black patients with Bowen's disease of the skin diagnosed between 194... more In a series of nineteen black patients with Bowen's disease of the skin diagnosed between 1948 and 1982, twenty-one lesions occurred. Involvement on non-sun-exposed areas was three times more common than on sun-exposed areas. The most common location was the lower extremity. A history of arsenic ingestion could not be confirmed in any of the patients, but was suggested by histopathologic findings in at least one instance. Invasive lesions developed in five patients, three of whom subsequently died from metastatic disease. Five patients also had a second noncutaneous malignancy.

Advances in Experimental Medicine and Biology, 1999

ABSTRACT The clinical, radiographic, and pathological findings in ten cases of intravascular lymp... more ABSTRACT The clinical, radiographic, and pathological findings in ten cases of intravascular lymphomatosis with central nervous system involvement seen at our institution over a 15- year period are presented. Nine patients presented with a subacute, progressive multifocal neurologic disorder. Most patients had fever, anemia, and elevation of the erythrocyte sedimentation rate. As the illness evolved, computerized tomography scanning and magnetic resonance imaging showed evidence of multifocal central nervous system disease. Angiography was nondiagnostic but suggested vasculitis in six cases. A response to empiric corticosteroid treatment was typical but usually transient. In six patients, the diagnosis was made antemortem by brain biopsy. The prognosis of patients was primarily dependent on early diagnosis and treatment, before massive central nervous system damage occurred. Treatment with chemotherapy, with or without radiotherapy, was associated with stabilization of the disease in three of five patients.

Seminars in Dermatology, 1995

The principal features of POEMS syndrome are osteosclerotic bone lesions, peripheral sensorimotor... more The principal features of POEMS syndrome are osteosclerotic bone lesions, peripheral sensorimotor neuropathy, and elevated levels of a monoclonal protein in the serum or urine. Skin lesions are present in the majority of patients with POEMS syndrome. Diffuse hyperpigmentation is the most common cutaneous finding. Hemangiomas with histopathological features resembling renal glomeruli are the most specific skin lesions.

Skeletal Radiology, 1998

Granuloma annulare, a relatively common cutaneous disorder of unknown origin, is named for its pr... more Granuloma annulare, a relatively common cutaneous disorder of unknown origin, is named for its predominantly papular lesions, which tend to group and coalesce in an annular fashion. Clinically distinct subtypes are divided into localized, generalized, perforating, and subcutaneous forms. Only the superficial granulomata of the extremities in subcutaneous granuloma annulare have been radiographically depicted in the literature. We describe and illustrate what we believe is the first radiographic presentation of bone and joint involvement with advanced, generalized granuloma annulare.

The Nurse Practitioner, 1997

Mayo Clinic Proceedings, 1997

Mayo Clinic Proceedings, 1993

Mayo Clinic Proceedings, 1994

To describe a patient with severe, recalcitrant mucous membrane erosions and chronic lymphocytic ... more To describe a patient with severe, recalcitrant mucous membrane erosions and chronic lymphocytic leukemia. We present a case report and a literature review of paraneoplastic pemphigus. Immunofluorescence studies and immunoprecipitation confirmed the presence of autoantibodies characteristic of paraneoplastic pemphigus in the patient&amp;amp;amp;amp;amp;#39;s serum. Our patient lived almost 8 years after the onset of paraneoplastic pemphigus, the longest time that anyone with this disease is known to have survived. The clinical course of paraneoplastic pemphigus tends to be rapid and fatal despite immunosuppressive therapy. Long-term survival is uncommon.

Journal of the American Academy of Dermatology, 1998

Drug-induced linear IgA bullous disease most commonly occurs after exposure to vancomycin, but ot... more Drug-induced linear IgA bullous disease most commonly occurs after exposure to vancomycin, but other medications may also trigger the eruption. We describe a 78-year-old man with linear IgA bullous disease related to treatment with phenytoin. (J Am Acad Dermatol 1998;38:352-6.)

Journal of the American Academy of Dermatology, 1995