Claudia Garcia - Academia.edu (original) (raw)

Papers by Claudia Garcia

arXiv (Cornell University), Jan 24, 2020

The Standard Model of fundamental interactions, albeit an incredibly elegant and successful theor... more The Standard Model of fundamental interactions, albeit an incredibly elegant and successful theory, lacks explanations for some experimental and theoretical open questions. Interestingly, many of these problems seem to be related to the electroweak symmetry breaking sector of the theory, whose dynamical generation is still unknown. Important questions such as what is the true nature of the Higgs boson, why is its mass so light and so close to that of the electroweak gauge bosons or whether the properties of this particle are the ones predicted in the Standard Model remain unanswered. The LHC is our tool to unveil these mysteries and vector boson scattering processes are the perfect window to access them, since they are considered as the most sensitive observables to new physics in the electroweak symmetry breaking sector. In this Thesis we employ the effective electroweak chiral Lagrangian with a light Higgs, which assumes a strongly interacting electroweak symmetry breaking sector, to perform a model independent analysis of the phenomenology of vector boson scattering processes at the LHC as well as to present quantitative predictions for the sensitivity to possible beyond the Standard Model physics scenarios.

International Journal of Dentistry

Background. The ceramics industry produces porcelain pastes using a controlled ratio of water and... more Background. The ceramics industry produces porcelain pastes using a controlled ratio of water and porcelain powder. Two methods are used to produce a dental porcelain paste: one-step mixing or incremental mixing. Objective. To evaluate the optical properties of a feldspathic dental ceramic using two different ceramic paste preparation methods using a Bayesian approach. Materials and Methods. Two groups of feldspathic porcelain discs, an incremental mixing group (n = 40) and a one-step mixing group (n = 40), were assessed. Groups were evaluated using spectrophotometry, and the translucency parameter (TP) of each sample was calculated. Surfaces were characterized by AFM and SEM. Statistical analysis was performed using a Bayesian approach. Results. Translucency parameter values of the incremental mixing group ranged from 1.65 to 3.41, while values for the one-step mixing group ranged from 3.62 to 5.74, this difference being statistically significant. The lowest roughness was obtained ...

Alzheimer's & Dementia, 2020

Background: The prevalence of cognitive disorders in the elderly population increases with time. ... more Background: The prevalence of cognitive disorders in the elderly population increases with time. Cognitive intervention is a broad field that uses different means to increase or maintain these capacities. Multifactor programs work with several aspects involved in cognitive processing simultaneously incorporating cognitive, metacognitive and psychosocial strategies. The aim of the present study is to implement and asses the efficacy of a multifactorial program for cognitive and metacognitive enhancement of selfvalidated older adults.

El acero inoxidable AISI 316L es el biomaterial mas utilizado para la fabricacion de implantes te... more El acero inoxidable AISI 316L es el biomaterial mas utilizado para la fabricacion de implantes temporales, pero estos presentan limitaciones para implantes permanentes, debido a la liberacion de iones metalicos. Una estrategia para minimizar la liberacion de iones, es la modificacion superficial de los implantes metalicos por medio de recubrimientos inorganicos ceramicos o vitreos aplicados por el metodo sol-gel. En el presente trabajo, se depositaron recubrimientos con particulas de wollastonita producidos por la tecnica sol-gel sobre acero inoxidable. Se evaluaron la estabilidad de las suspensiones y la biocompatibilidad de los recubrimientos mediante ensayos in Vitro en fluido fisiologico simulado (SBF).

Revista Brasileira de Ciências do Esporte, 2011

O objetivo deste estudo foi investigar o desempenho e a contribuição da informação visual no cont... more O objetivo deste estudo foi investigar o desempenho e a contribuição da informação visual no controle postural de crianças praticantes e não praticantes de ginástica artística (GA). Quarenta e três meninas, 23 praticantes de GA e 20 não praticantes de GA, idade 5 a 7 e 9 a 11 anos, permaneceram em pé sobre uma plataforma de força em três bases de apoio: bipodal, semi-tandem stance e base reduzida, com olhos abertos e com olhos fechados. A área de deslocamento do centro de pressão e o índice de contribuição visual foram calculados. Os resultados indicaram que a prática de GA melhora o controle postural de crianças nos anos iniciais de desenvolvimento. Ainda, crianças praticantes de GA utilizam melhor informação visual que crianças não praticantes de GA para manter a postura ereta mais estável.

Photodiagnosis and Photodynamic Therapy, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Proceedings of XIII Quark Confinement and the Hadron Spectrum — PoS(Confinement2018), 2019

Nuclear Physics B, 2019

In this work we explore the sensitivity to the Higgs self-coupling λ in the production of two Hig... more In this work we explore the sensitivity to the Higgs self-coupling λ in the production of two Higgs bosons via vector boson scattering at the LHC. Although these production channels, concretely W + W − → HH and ZZ → HH, have lower rates than gluon-gluon fusion, they benefit from being tree level processes, being independent of top physics and having very distinctive kinematics that allow us to obtain very clean experimental signatures. This makes them competitive channels concerning the sensitivity to the Higgs self-coupling. In order to give predictions for the sensitivity to this coupling, we first study the role of λ at the subprocess level, both in and beyond the Standard Model, to move afterwards to the LHC scenario. We characterize the pp → HHjj case first and then provide quantitative results for the values of λ that can be probed at the LHC in vector boson scattering processes after considering the Higgs boson decays. We focus mainly on pp → bbbbjj, since it has the largest signal rates, and also comment on the potential of other channels, such as pp → bbγγjj, as they lead to cleaner, although smaller, signals. Our whole study is performed for a center of mass energy of √ s = 14 TeV and for various future expected LHC luminosities.

Brazilian Journal of Motor Behavior, 2009

The goal of this study was to compare two methods of analysis, the use of force platform and base... more The goal of this study was to compare two methods of analysis, the use of force platform and based on video system, to investigate the postural control of young adults during upright stance on three bases of support. Fifteen young adults (30±4.96 years old) were asked to maintain an upright and quiet stance on a force platform for 30 s on bipedal, semi-tandem stance, and reduced bipedal bases of support. One reflective marker was placed on their back to acquire the space coordinates. Mean sway amplitude and mean velocity in anterior-posterior (AP) and medial-lateral (ML) directions and the area of stabilogram were calculated and used to compare the two methods of analysis and the effects of bases of support. Coefficient of correlation values indicated strong relation between trajectories of center of pressure and reflective marker in both directions (AP and ML), and statistical analysis of both methods indicated similar results in terms of effects of base of support. According to th...

Plant Cell, Tissue and Organ Culture (PCTOC), 2019

Somatic embryogenesis is a morphogenetic event where somatic cells have the ability to produce em... more Somatic embryogenesis is a morphogenetic event where somatic cells have the ability to produce embryos without gamete fusion. It is used as a technique for plant mass propagation. It is a process that has six well defined steps such as induction, expression, development, maturation, germination and plant conversion. These steps are characterized by distinct physiological, morphological and molecular events. Although somatic embryogenesis has been established in several plant species, there remains many problems to be solved. The main problem in somatic embryogenesis is the large number of abnormal embryos produced which cannot germinate nor convert into normal plants. Abnormalities in somatic embryos (SE) can be generated by genetic or epigenetic changes in the DNA. These changes in the DNA can be influenced by external factors such as the use of plant growth regulators and mutagenic substances or stress factors applied to the plant tissue such as high and low temperatures, drought, salinity, and heavy metals. Abnormalities generated by genetic changes in the DNA are hardly reversible; however, abnormalities generated by epigenetic changes may be reversible and the abnormal embryos are able to produce normal plants in most cases. This review focuses on the identification of the main factors that can cause abnormal SE development in different plant species, suggest how SE abnormalities are related to somaclonal variations and identify which genes may be involved with embryo abnormalities. Zygotic embryo abnormalities in Arabidopsis thaliana mutants are listed with the aim to understand the main genetic mechanisms involved in embryo aberrations. Key message The abnormalities in somatic embryos are related to the use of 2,4-D in most of the published protocols, this sintetic auxin disrupts the endogenous auxin balance and the auxin polar transportation interfering with the embryo apical-basal polarity.

Methods in molecular biology (Clifton, N.J.), 2018

Theobroma cacao L. is a tropical tree originating in the Amazon, where it grows naturally in the ... more Theobroma cacao L. is a tropical tree originating in the Amazon, where it grows naturally in the shade of tropical rainforests. Cacao sub-products, such as butter and powder, are produced as principal components of chocolate and contain important nutritional compounds such as polyphenols and flavonoids. However, bean production is decreasing because plantations are antiquated and unproductive. Cacao propagation has been traditionally performed through classical propagation methods, such as grafting or rooted cuttings, but those methods are not sufficient to obtain large quantities of planting material with the desired genetic quality and optimal plant health. In the search for solutions to this problem, somatic embryogenesis (SE) is a vegetative method used for cacao propagation that has the potential to be explored. SE is a type of clonal propagation by which totipotent cells in the somatic tissue can develop into embryos and subsequently convert into plants.This method offers sign...

NeuroImage: Clinical, 2016

Complete removal of epileptogenic cortex while preserving eloquent areas is crucial in patients u... more Complete removal of epileptogenic cortex while preserving eloquent areas is crucial in patients undergoing epilepsy surgery. In this manuscript, the feasibility was explored of developing a new methodology based on dynamic intrinsic optical signal imaging (DIOSI) to intraoperatively detect and differentiate epileptogenic from eloquent cortices in pediatric patients with focal epilepsy. From 11 pediatric patients undergoing epilepsy surgery, negatively-correlated hemodynamic low-frequency oscillations (LFOs,~0.02-0.1 Hz) were observed from the exposed epileptogenic and eloquent cortical areas, as defined by electrocorticography (ECoG), using a DIOSI system. These LFOs were classified into multiple groups in accordance with their unique temporal profiles. Causal relationships within these groups were investigated using the Granger causality method, and 83% of the ECoG-defined epileptogenic cortical areas were found to have a directed influence on one or more cortical areas showing LFOs within the field of view of the imaging system. To understand the physiological origins of LFOs, blood vessel density was compared between epileptogenic and normal cortical areas and a statisticallysignificant difference (p b 0.05) was detected. The differences in blood-volume and blood-oxygenation dynamics between eloquent and epileptogenic cortices were also uncovered using a stochastic modeling approach. This, in turn, yielded a means by which to separate epileptogenic from eloquent cortex using hemodynamic LFOs. The proposed methodology detects epileptogenic cortices by exploiting the effective connectivity that exists within cortical regions displaying LFOs and the biophysical features contributed by the altered vessel networks within the epileptogenic cortex. It could be used in conjunction with existing technologies for epileptogenic/eloquent cortex localization and thereby facilitate clinical decision-making.

Current Nutrition & Food Science, 2007

... total calorie per gram 3,854; crude protein 7.62%; crude fat 1.61%; acid detergent fiber 4.23... more ... total calorie per gram 3,854; crude protein 7.62%; crude fat 1.61%; acid detergent fiber 4.23%; phosphorous 0.18%; magnesium 0.09%; calcium 0.31%; iron 11 ppm; manganese 2 ppm; copper 4 ppm; zinc 5 ppm 2Vitamin Mixture Composition (AIN-93; Harlan Teklad, Madison ...

World Allergy Organization Journal, 2012

Binding of human IgE to anisakis and house dust mite proteins was investigated by immunoblot with... more Binding of human IgE to anisakis and house dust mite proteins was investigated by immunoblot with serum from individuals sensitized to anisakis or shrimp. IgE binding patterns in the immunoblots were used for the identification of major Anisakis allergens, which were analysed by mass spectrometry-based proteomics in ESI-Orbitrap, after separation on SDS-gel. Results: Four new allergen candidates were identified. The first identified allergen was enolase, which is related to the cockroach allergen enolase. The other allergens were Heat Shock Protein-70 (HSP 70), tubulin, and glutathion-S-transferase, which are also present as allergens in house dust mite. Conclusions: Here we describe the identification of 4 novel IgE binding allergens in anisakis. The allergens might explain IgE cross-reactivity between anisakis and house dust mite or cockroach. 51%, followed by wheat meal, rye Meal, and other foods in smaller proportions. Moreover, in 46 patients with known clinical history, including gastrointestinal symptoms, respiratory symptoms, pervasive developmental disorder (PDD) and autism, we detected levels of specific IgG to a significant number of foods simultaneously.

Archives of Sexual Behavior, 2014

This study assessed HIV prevalence and associated factors in 284 male-to-female transsexuals from... more This study assessed HIV prevalence and associated factors in 284 male-to-female transsexuals from southern Brazil. Seroprevalence was 25 %. Seroprevalence was higher and associated with older age, residence in the metropolitan area, history of diagnosis of other STDs, and reported history of sex work. The year of diagnosis showed no significant relationship with the prevalence of HIV nor the fact of being in a stable relationship, a history of drug use, years of education, and race/ethnicity. The odds of HIV infection compared with the general Brazilian population was 55.55 (95 % CI 38.39-80.39). Changes in the views of the vulnerable groups to HIV/AIDS in Brazil and efforts in the construction of strategies of prevention and in the guarantee of human rights are required.

1 . They build on the collective experiences of the International Research Network on Violence Ag... more 1 . They build on the collective experiences of the International Research Network on Violence Against Women. We would like to acknowledge the able guidance of the WHO Expert Steering Committee of the Study and the valuable input of the Scientific and Ethical Review Group (SERG) of the WHO Special Programme of Research, Development and Research Training in Human Reproduction, in particular Ruth Macklin.

The International Journal of Developmental Biology, 2004

Members of the TGFβ β β β β superfamily of growth and differentiation factors, including the TGFβ... more Members of the TGFβ β β β β superfamily of growth and differentiation factors, including the TGFβ β β β β, BMP, activin and nodal families, play important signaling roles throughout development. This paper summarizes some of the functions of these ligands in lens development. Targeted deletion of the genes encoding one of the BMP receptors, Alk3 (BMP receptor-1A), showed that signaling through this receptor is essential for normal lens development. Lenses lacking Alk3 were smaller than normal, with thin epithelial layers. The fiber cells of Alk3 null lenses became vacuolated and degenerated within the first week after birth. Lenses lacking Alk3 function were surrounded by abnormal mesenchymal cells, suggesting that the lenses provided inappropriate signals to surrounding tissues. Lens epithelial and fiber cells contained endosomes that were associated with activated (phosphorylated) SMAD1 and SMAD2. Endosomal localization of pSMAD1 was reduced in the absence of Alk3 signaling. The presence of pSMAD2 in lens fiber cell nuclei and the observation that the activin antagonist follistatin inhibited lens cell elongation suggested that an activin-like molecule participates in lens fiber cell differentiation. Lenses deficient in type II TGFβ β β β β receptors were clear and had fiber cells of normal morphology. This suggests that TGFβ β β β β signaling is not essential for the normal differentiation of lens fiber cells. The targeted deletion of single or multiple receptors of the TGFβ β β β β superfamily in the lens should further characterize the role of these signaling molecules in lens development. This approach may also provide a useful way to define the downstream pathways that are activated by these receptors during the development of the lens and other tissues.