Coskun Celtik - Academia.edu (original) (raw)

Papers by Coskun Celtik

Research paper thumbnail of The prevalence of folic acid deficiency among adolescent girls living in Edirne, Turkey

Journal of Adolescent Health, May 1, 2006

Research paper thumbnail of Süt Çocuğu Dönemi Konvülsiyonları ve Serebral Venöz Sinüs Trombozunun Önemi

Turkiye Klinikleri Journal of Pediatrics, 2003

Research paper thumbnail of İntrauterin Yaşamda Barsak Perforasyonu Gelişen İki Kistik Fibrozis Olgusu

Turkiye Klinikleri Journal of Pediatrics, 2005

Research paper thumbnail of Sodyum Valproat Tedavisi Alan Bir Çocukta Fulminan Hepatit-A

Turkiye Klinikleri Journal of Pediatrics, 2010

Research paper thumbnail of Sensitization to common allergens, especially pollens, among children with respiratory allergy in the Trakya region of Turkey

PubMed, Dec 1, 2004

Asthma and allergic rhinitis are common problems in children and the causative pollen allergens v... more Asthma and allergic rhinitis are common problems in children and the causative pollen allergens vary according to the geographical area. The aim of this study was to investigate patterns of sensitization to common inhalant allergens, especially pollens, in Turkish children living in the Trakya region and to determine differences between rural and urban areas. Allergen skin testing was prospectively performed on 539 children aged between 4 and 17 years with respiratory allergy. The reaction was considered to be positive if the mean wheal diameter was at least 3 mm greater than that of the negative controls. We detected positive skin reactions in 420 (77.9%) children. Two hundred and eighty-one (52.1%) mite, 277 (51.4%) pollen, 174 (32.3%) mold, 65 (12.1%) animal dander, 12 (2.2%) cockroach and 6 (1.1%) latex skin sensitivities were detected. Among the pollen allergies 173 were cereal pollen (32.1%), 170 grass pollen (31.5%) and 144 tree pollen allergies (26.7%). The most common positive skin test among the pollens was to cultivated wheat (Titicum vulgare) (n = 116, 21,5%), followed by rye grass (Lolium perenne) and orchard grass (Dactylis glomerata). Positive skin reactions to Alternaria, to Candida albicans, and to all pollens except Ulmus competris, Pinus sylvetris, Platanus vulgaris and Tilia platyphyllos, were higher in children with allergic rhinitis than in those with asthma. In children from rural areas, allergic skin reactivity was found to be more common against Candida albicans, sheep dander and all pollens except Corylus avellana, Fraxinus excelsior, Populus alba, Pinus sylvetris, Platanus vulgaris and Chenopodium album, than in urban children. Although Trakya is close to Greece and other Mediterranean countries, this study suggests that the pollens, which sensitize children, are not similar.

Research paper thumbnail of Seftriakson ve Pseudolithiasis: Olgu Sunumu

Turkiye Klinikleri Journal of Pediatrics, 2002

Research paper thumbnail of Perinatal Asfiksili Yenidoğanların Etyoloji Klinik ve Prognoz Açısından Değerlendirilmesi

Turkiye Klinikleri Journal of Pediatrics, 1999

Timi olgular cinsiyet dağılımı, geslasyoııel yaş, dağımı tartısı ortalamaları risk faktörleri, kl... more Timi olgular cinsiyet dağılımı, geslasyoııel yaş, dağımı tartısı ortalamaları risk faktörleri, klinik özelliklerin dağılımı yönünden değerlendirildi. Terin olgular IIİ]ioksik Iskemik Ensefalopati bul­ guları açısından Sarimi ev. Sarınıl Evreleııdırıııe Sısıeıııiııe göre evreleııairildi. Morialile oranları, hastanede kalım sureleri, 3.6.12.aylarda yapılan Deliver Gelişimsel Tarama Testi ve görün­ tüleme Yöntemleri ile majör motor defisil oranları belirlendi.

Research paper thumbnail of Neuron-specific enolase as a marker of the severity and outcome of hypoxic ischemic encephalopathy

Brain & Development, Sep 1, 2004

Research paper thumbnail of Segmental intestinal dilatation associated with omphalocele

Pediatrics International, Apr 1, 2005

Research paper thumbnail of Thrombocytopenia: An important indicator for the application of partial exchange transfusion in polycythemic newborn infants?

Pediatrics International, Aug 16, 2000

Background: The conventional therapeutic approach in polycythemic newborn infants is to apply par... more Background: The conventional therapeutic approach in polycythemic newborn infants is to apply partial exchange transfusion (PET) when hematocrit value exceeds 70% or when the infant develops symptoms with the exception of plethora. Methods : In order to investigate the possibility of using platelet count as a simple criterion implying the PET requirement, we retrospectively reviewed polycythemic newborn infants with respect to the relationship between thrombocytopenia and severity of symptoms, and the association of platelet count and the PET performance. Thrombocytopenia has been defined as a platelet count <150 000/μL. Results : We studied 18 polycythemic infants with thrombocytopenia (group 1, 35%) and 34 without it (group 2, 65%). Perinatal asphyxia, gestational toxemia and intrauterine growth retardation, which are the three common causative factors leading to polycythemia, were not significantly different in the two groups. No correlation existed between platelet counts and hematocrit values within each group, but there was a very significant difference between the two groups in terms of severity of clinical findings (P<0001); no difference in terms of moderate findings and moderately significant difference with respect to mild symptoms and asymptomatic situation (P<0.05). Partial exchange transfusion was performed in all patients in group 1, while only 12 infants in group 2 (32%) received transfusion and the difference was statistically significant (P<0.05). A significant rise in platelet counts has been achieved only in group 1, while hematocrit values decreased significantly in both groups following PET. Conclusions : This study emphasizes the relationship between thrombocytopenia and the severity of clinical findings and PET performance rate in polycythaemic newborn infants, implying that thrombocytopenia is a possible marker of hyperviscosity, the results of which warrant further investigation.

Research paper thumbnail of Seroprevalence of autoimmune thyroiditis and celiac disease in children with insulin-dependent diabetes mellitus in the Thrace region of Turkey

The Turkish journal of gastroenterology, Sep 1, 2010

We aimed to estimate the seroprevalence of celiac disease, a gluten-sensitive enteropathy, and au... more We aimed to estimate the seroprevalence of celiac disease, a gluten-sensitive enteropathy, and autoimmune thyroiditis in children with insulin-dependent diabetes mellitus in the Thrace region of Turkey. The population studied consisted of 33 children with insulin-dependent diabetes mellitus and 41 healthy children with demographic features similar to the study subjects. Free triiodothyronine, free thyroxine, thyroid-stimulating hormone, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, IgA, anti-endomysium IgA, and anti-gliadin IgA were measured in all cases and controls. The serum levels of free triiodothyronine and free thyroxine were within the normal range in all cases. However, in one patient who had anti-thyroid peroxidase and antithyroglobulin antibodies, the thyroid-stimulating hormone level was high despite a normal free triiodothyronine and free thyroxine value. Ultrasonographic findings confirmed thyroiditis in this patient. Anti-thyroid peroxidase antibodies, anti-thyroglobulin antibodies, anti-endomysium IgA and anti-gliadin IgA were detected in 15.4%, 6%, 9.1% and 3% of the diabetic cases, respectively. None of these antibodies was detected in the control group. In the diabetic group, the seroprevalences of the antithyroid peroxidase antibodies and the anti-endomysium IgA were statistically higher than in the control group (p<0.05). Children with insulin-dependent diabetes mellitus in our region should undergo periodic screenings for autoimmune thyroiditis and celiac disease.

Research paper thumbnail of Serum Glucose, Insulin, C-Peptide and Lipid Levels in Response to Low Versus High Glycaemic Index Breakfast in Exogeneous Obese Adolescents

Archives of Disease in Childhood, Nov 1, 2008

Objective The aim of this study was to determine serum glucose, insulin and lipid levels in respo... more Objective The aim of this study was to determine serum glucose, insulin and lipid levels in response to two different types of traditional breakfasts, one with a low glycaemic index (meal 1) and the other with a high glycaemic index (meal 2) that were prepared under supervision of a research dietitian and given to exogeneous obese adolescents. Methods Ten boys and 10 girls with a mean age of 12.5 ± 1.35 years were recruited to the study. Two different traditional meals were given after 12-h fasting on different days. Venous blood samples were taken from the subjects for glucose at the beginning of the study and at 30, 60 and 120 minutes after consumption of meals. C-peptide, insulin and lipid profiles were determined at 60th minute after each meal. Results Blood glucose values after meal 2 were higher compared with the consumption of meal 1. However, there was no significant difference among meals in terms of blood glucose levels. The increase in C-peptide and insulin values after meal 1 and meal 2 was compatible with previous data. Consumption of meal 2 caused a remarkable increase in insulin, C-peptide values, but the only significant difference between the two meals was in C-peptide values, being higher in those after meal 2. Conclusions Our findings are similar to previous reports, which have shown that the consumption of high glycaemic index foods may cause hyperglycaemia and lead to obesity. However, our study was a 2-h long study, which limits its value, therefore we conclude that larger and longer studies are required in order to determine the metabolic effects of glycaemic index.

Research paper thumbnail of Case report: Silver Russel syndrome: clinical presentation of three cases

American Journal of Case Reports, Apr 20, 2004

Research paper thumbnail of Investigation of indoor molds and allergic diseases in public primary schools in Edirne city of Turkey

PubMed, Mar 1, 2011

Background: Studies evaluating the role of indoor molds in the development of allergic or respira... more Background: Studies evaluating the role of indoor molds in the development of allergic or respiratory symptoms in schools are few in childhood. Objective: This study aimed to investigate relation between indoor molds and allergic diseases or respiratory symptoms in primary school's children in Edirne, Turkey. Methods: Ten public primary schools were included into the study. A thorough assessment, using a questionnaire and inspection surveys was carried out. The concentration of culturable mold was assessed in the dust samples in the schools. Indoor temperature and humidity were measured. A total of 1374 students who completed valid questionnaires were included in the study, and dust-samples were collected from the schools. Results: Cumulative and current prevalence rates of wheezing, asthma, allergic rhinitis, and atopic dermatitis were found as 31.4%, 9.3%, 16.2%, 6.0% and 13.4%, 11.9%, 15.1%, 2.1%, respectively. The most frequent mold-species detected in indoor dusts were Cladosporium, Penicillium, Alternaria and Aspergillus. Although the prevalence rates of allergic diseases and respiratory symptoms were high, indoor mold amounts were low in the schools in our region and no significant correlation was determined between indoor mold amount and the prevalence of these diseases in schools or classrooms. Conclusion: Even though allergic molds are present in schools, the mold-exposure may not be an important predisposing factor for development of allergic and respiratory diseases the schools in our region.

Research paper thumbnail of Çocuklarda Antiepileptik Ilaçların Serum Lipid Profili Üzerine Olan Etkileri Ve Aterosklerozun Erken Belirleyicileri Olan Lipoprotein (A) Düzeyi Ve Karotis Arter Intima Media Kalınlığı Ile Değerlendirilmesi

Amac: Epilepsi kronik bir hastalik olup, uzun sureli tedavinin varligi bu ilaclara bagli yan etki... more Amac: Epilepsi kronik bir hastalik olup, uzun sureli tedavinin varligi bu ilaclara bagli yan etkilerin ortaya cikmasina zemin hazirlamaktadir. Bu calismada antiepileptik ilaclardan valproat ve karbamazepinin ateroskleroz olusumu uzerine olan etkilerini, serum lipid profili, aterosklerozun erken belirleyicileri olan lipoprotein(a) duzeyi ve karotis intima media kalinligi ile arastirilmasi amaclandi. Gerec ve Yontemler: Calismaya Trakya Universitesi Tip Fakultesi Cocuk Noroloji birimimizde Temmuz 2005-Aralik 2006 tarihleri arasinda 2-14 yas araligindaki 27’si Valproat, 12’si Karbamazepin tedavisi alan 39 epileptik hasta ile yas ve cinsiyet acisindan uyumlu 30 saglam cocuk kontrol grubuna alindi. Calisma oncesi tarti, boy ve vucut kitle indeksi degerleri kaydedildi. Tum olgularin tedavi baslangicinda, 12 saatlik aclik sonrasi serum trigliserid, total kolesterol, dusuk dansiteli lipoprotein kolesterol, yuksek dansiteli lipoprotein kolesterol ve lipoprotein(a) tayini icin kan ornekler...

Research paper thumbnail of Trakya bölgesinde çocuklarda görülen zehirlenmeler Orijinal Araştırma

Turk Pediatri Arsivi-turkish Archives of Pediatrics, 2004

Zehirlenmeye yol acan etkenler yasanilan bolgeye toplumun gelenek ve geleneklerine ailenin egitim... more Zehirlenmeye yol acan etkenler yasanilan bolgeye toplumun gelenek ve geleneklerine ailenin egitim duzeyine ve mevsimlere gore degiskenlik gosterebilir Bu calismanin amaci hastanemizde son 5 yil icinde yatirilarak tedavi edilen zehirlenme olgularinin ozelliklerini gozden gecirmektir Ocak 1998 Mayis 2003 tarihleri arasinda zehirlenme tanisi ile yatirilarak tedavi edilen olgularin dosyalari geriye donuk olarak degerlendirildi Olgularin dosya kayitlari incelenerek yas cinsiyet aldigi madde veya ilac karsilasma yolu semptomlar klinik bulgular komplikasyonlar yogun bakim gereksinimi acisindan degerlendirildi Zehirlenme olgularinin tum acil cocuk basvurularina orani 1 6’ydi Iki yuz yirmi yedi olgunun 112’si 49 3 kiz 115’i 50 7 erkekti ve olgularin ortalama yasi 4 5±3 4 1 16 yildi Ilaclar en sik zehirlenme nedeniydi ve ilaclari koroziv maddeler izlemekteydi Olgularin 4 4’unde Pediatrik Yogun Bakim gereksinimi oldu Uc olgu koroziv madde n=2 ve kolsisin n=1 alimi nedeniyle kaybedildi Zehirlen...

Research paper thumbnail of Neonatal Respiratuar Sinsitiyal Virüs Enfeksiyonu

Balkan Medical Journal, 2000

Research paper thumbnail of A Case of Noonan Syndrome Associated with Atrial Septal Defect

Research paper thumbnail of Listeria Monositogenez Menenjitli Bir Olgu Sunumu

Turk Pediatri Arsivi-turkish Archives of Pediatrics, Jun 1, 1999

Yuksek ates kusma uykuya egilim yakinmasiyla getirilen stupor halindeki 3 yasindaki erkek hastada... more Yuksek ates kusma uykuya egilim yakinmasiyla getirilen stupor halindeki 3 yasindaki erkek hastada beyin omurilik sivisi incelemesinde ksantokromi protein yuksekligi lenfosit hakimiyeti saptanmasi uzerine antituberkuloz tedavi baslandi ikinci gunu kaybedilen postmortem BOS kulturunde Listeria Monositogenez ureyen olgu bu yas grubunda Listeriozisin nadir olmasi ve olgunun belirgin bir risk faktoru tasimamasi nedeniyle sunulmustur Anahtar kelimeler: Listeria Monositogenez Menenjit Tuberkuloz

Research paper thumbnail of Cirrhotic Cardiomyopathy

InTech eBooks, Apr 12, 2017

Cirrhotic cardiomyopathy (CCMP) is a functional disorder characterized by electrophysiologic dist... more Cirrhotic cardiomyopathy (CCMP) is a functional disorder characterized by electrophysiologic disturbances and diastolic and/or systolic dysfunction in patients with chronic liver disease, especially those with ascites and portal hypertension. This disorder is a well-defined entity in adults, but pediatric data are limited. Clinical and laboratory findings are generally latent. The diagnostic criteria are prolonged QT on electrocardiography due to metabolic and extrahepatic causes, in addition to some abnormal echocardiography findings. If echocardiographic findings are normal and only specific prolonged QT is present, this disorder is named as "latent CCMP"; otherwise, it is "manifest CCMP." This disorder is important because it may lead to problems such as cardiac failure and dysrhythmia before or after liver transplantation. Moreover, it may worsen the prognosis.

Research paper thumbnail of The prevalence of folic acid deficiency among adolescent girls living in Edirne, Turkey

Journal of Adolescent Health, May 1, 2006

Research paper thumbnail of Süt Çocuğu Dönemi Konvülsiyonları ve Serebral Venöz Sinüs Trombozunun Önemi

Turkiye Klinikleri Journal of Pediatrics, 2003

Research paper thumbnail of İntrauterin Yaşamda Barsak Perforasyonu Gelişen İki Kistik Fibrozis Olgusu

Turkiye Klinikleri Journal of Pediatrics, 2005

Research paper thumbnail of Sodyum Valproat Tedavisi Alan Bir Çocukta Fulminan Hepatit-A

Turkiye Klinikleri Journal of Pediatrics, 2010

Research paper thumbnail of Sensitization to common allergens, especially pollens, among children with respiratory allergy in the Trakya region of Turkey

PubMed, Dec 1, 2004

Asthma and allergic rhinitis are common problems in children and the causative pollen allergens v... more Asthma and allergic rhinitis are common problems in children and the causative pollen allergens vary according to the geographical area. The aim of this study was to investigate patterns of sensitization to common inhalant allergens, especially pollens, in Turkish children living in the Trakya region and to determine differences between rural and urban areas. Allergen skin testing was prospectively performed on 539 children aged between 4 and 17 years with respiratory allergy. The reaction was considered to be positive if the mean wheal diameter was at least 3 mm greater than that of the negative controls. We detected positive skin reactions in 420 (77.9%) children. Two hundred and eighty-one (52.1%) mite, 277 (51.4%) pollen, 174 (32.3%) mold, 65 (12.1%) animal dander, 12 (2.2%) cockroach and 6 (1.1%) latex skin sensitivities were detected. Among the pollen allergies 173 were cereal pollen (32.1%), 170 grass pollen (31.5%) and 144 tree pollen allergies (26.7%). The most common positive skin test among the pollens was to cultivated wheat (Titicum vulgare) (n = 116, 21,5%), followed by rye grass (Lolium perenne) and orchard grass (Dactylis glomerata). Positive skin reactions to Alternaria, to Candida albicans, and to all pollens except Ulmus competris, Pinus sylvetris, Platanus vulgaris and Tilia platyphyllos, were higher in children with allergic rhinitis than in those with asthma. In children from rural areas, allergic skin reactivity was found to be more common against Candida albicans, sheep dander and all pollens except Corylus avellana, Fraxinus excelsior, Populus alba, Pinus sylvetris, Platanus vulgaris and Chenopodium album, than in urban children. Although Trakya is close to Greece and other Mediterranean countries, this study suggests that the pollens, which sensitize children, are not similar.

Research paper thumbnail of Seftriakson ve Pseudolithiasis: Olgu Sunumu

Turkiye Klinikleri Journal of Pediatrics, 2002

Research paper thumbnail of Perinatal Asfiksili Yenidoğanların Etyoloji Klinik ve Prognoz Açısından Değerlendirilmesi

Turkiye Klinikleri Journal of Pediatrics, 1999

Timi olgular cinsiyet dağılımı, geslasyoııel yaş, dağımı tartısı ortalamaları risk faktörleri, kl... more Timi olgular cinsiyet dağılımı, geslasyoııel yaş, dağımı tartısı ortalamaları risk faktörleri, klinik özelliklerin dağılımı yönünden değerlendirildi. Terin olgular IIİ]ioksik Iskemik Ensefalopati bul­ guları açısından Sarimi ev. Sarınıl Evreleııdırıııe Sısıeıııiııe göre evreleııairildi. Morialile oranları, hastanede kalım sureleri, 3.6.12.aylarda yapılan Deliver Gelişimsel Tarama Testi ve görün­ tüleme Yöntemleri ile majör motor defisil oranları belirlendi.

Research paper thumbnail of Neuron-specific enolase as a marker of the severity and outcome of hypoxic ischemic encephalopathy

Brain & Development, Sep 1, 2004

Research paper thumbnail of Segmental intestinal dilatation associated with omphalocele

Pediatrics International, Apr 1, 2005

Research paper thumbnail of Thrombocytopenia: An important indicator for the application of partial exchange transfusion in polycythemic newborn infants?

Pediatrics International, Aug 16, 2000

Background: The conventional therapeutic approach in polycythemic newborn infants is to apply par... more Background: The conventional therapeutic approach in polycythemic newborn infants is to apply partial exchange transfusion (PET) when hematocrit value exceeds 70% or when the infant develops symptoms with the exception of plethora. Methods : In order to investigate the possibility of using platelet count as a simple criterion implying the PET requirement, we retrospectively reviewed polycythemic newborn infants with respect to the relationship between thrombocytopenia and severity of symptoms, and the association of platelet count and the PET performance. Thrombocytopenia has been defined as a platelet count <150 000/μL. Results : We studied 18 polycythemic infants with thrombocytopenia (group 1, 35%) and 34 without it (group 2, 65%). Perinatal asphyxia, gestational toxemia and intrauterine growth retardation, which are the three common causative factors leading to polycythemia, were not significantly different in the two groups. No correlation existed between platelet counts and hematocrit values within each group, but there was a very significant difference between the two groups in terms of severity of clinical findings (P<0001); no difference in terms of moderate findings and moderately significant difference with respect to mild symptoms and asymptomatic situation (P<0.05). Partial exchange transfusion was performed in all patients in group 1, while only 12 infants in group 2 (32%) received transfusion and the difference was statistically significant (P<0.05). A significant rise in platelet counts has been achieved only in group 1, while hematocrit values decreased significantly in both groups following PET. Conclusions : This study emphasizes the relationship between thrombocytopenia and the severity of clinical findings and PET performance rate in polycythaemic newborn infants, implying that thrombocytopenia is a possible marker of hyperviscosity, the results of which warrant further investigation.

Research paper thumbnail of Seroprevalence of autoimmune thyroiditis and celiac disease in children with insulin-dependent diabetes mellitus in the Thrace region of Turkey

The Turkish journal of gastroenterology, Sep 1, 2010

We aimed to estimate the seroprevalence of celiac disease, a gluten-sensitive enteropathy, and au... more We aimed to estimate the seroprevalence of celiac disease, a gluten-sensitive enteropathy, and autoimmune thyroiditis in children with insulin-dependent diabetes mellitus in the Thrace region of Turkey. The population studied consisted of 33 children with insulin-dependent diabetes mellitus and 41 healthy children with demographic features similar to the study subjects. Free triiodothyronine, free thyroxine, thyroid-stimulating hormone, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, IgA, anti-endomysium IgA, and anti-gliadin IgA were measured in all cases and controls. The serum levels of free triiodothyronine and free thyroxine were within the normal range in all cases. However, in one patient who had anti-thyroid peroxidase and antithyroglobulin antibodies, the thyroid-stimulating hormone level was high despite a normal free triiodothyronine and free thyroxine value. Ultrasonographic findings confirmed thyroiditis in this patient. Anti-thyroid peroxidase antibodies, anti-thyroglobulin antibodies, anti-endomysium IgA and anti-gliadin IgA were detected in 15.4%, 6%, 9.1% and 3% of the diabetic cases, respectively. None of these antibodies was detected in the control group. In the diabetic group, the seroprevalences of the antithyroid peroxidase antibodies and the anti-endomysium IgA were statistically higher than in the control group (p<0.05). Children with insulin-dependent diabetes mellitus in our region should undergo periodic screenings for autoimmune thyroiditis and celiac disease.

Research paper thumbnail of Serum Glucose, Insulin, C-Peptide and Lipid Levels in Response to Low Versus High Glycaemic Index Breakfast in Exogeneous Obese Adolescents

Archives of Disease in Childhood, Nov 1, 2008

Objective The aim of this study was to determine serum glucose, insulin and lipid levels in respo... more Objective The aim of this study was to determine serum glucose, insulin and lipid levels in response to two different types of traditional breakfasts, one with a low glycaemic index (meal 1) and the other with a high glycaemic index (meal 2) that were prepared under supervision of a research dietitian and given to exogeneous obese adolescents. Methods Ten boys and 10 girls with a mean age of 12.5 ± 1.35 years were recruited to the study. Two different traditional meals were given after 12-h fasting on different days. Venous blood samples were taken from the subjects for glucose at the beginning of the study and at 30, 60 and 120 minutes after consumption of meals. C-peptide, insulin and lipid profiles were determined at 60th minute after each meal. Results Blood glucose values after meal 2 were higher compared with the consumption of meal 1. However, there was no significant difference among meals in terms of blood glucose levels. The increase in C-peptide and insulin values after meal 1 and meal 2 was compatible with previous data. Consumption of meal 2 caused a remarkable increase in insulin, C-peptide values, but the only significant difference between the two meals was in C-peptide values, being higher in those after meal 2. Conclusions Our findings are similar to previous reports, which have shown that the consumption of high glycaemic index foods may cause hyperglycaemia and lead to obesity. However, our study was a 2-h long study, which limits its value, therefore we conclude that larger and longer studies are required in order to determine the metabolic effects of glycaemic index.

Research paper thumbnail of Case report: Silver Russel syndrome: clinical presentation of three cases

American Journal of Case Reports, Apr 20, 2004

Research paper thumbnail of Investigation of indoor molds and allergic diseases in public primary schools in Edirne city of Turkey

PubMed, Mar 1, 2011

Background: Studies evaluating the role of indoor molds in the development of allergic or respira... more Background: Studies evaluating the role of indoor molds in the development of allergic or respiratory symptoms in schools are few in childhood. Objective: This study aimed to investigate relation between indoor molds and allergic diseases or respiratory symptoms in primary school's children in Edirne, Turkey. Methods: Ten public primary schools were included into the study. A thorough assessment, using a questionnaire and inspection surveys was carried out. The concentration of culturable mold was assessed in the dust samples in the schools. Indoor temperature and humidity were measured. A total of 1374 students who completed valid questionnaires were included in the study, and dust-samples were collected from the schools. Results: Cumulative and current prevalence rates of wheezing, asthma, allergic rhinitis, and atopic dermatitis were found as 31.4%, 9.3%, 16.2%, 6.0% and 13.4%, 11.9%, 15.1%, 2.1%, respectively. The most frequent mold-species detected in indoor dusts were Cladosporium, Penicillium, Alternaria and Aspergillus. Although the prevalence rates of allergic diseases and respiratory symptoms were high, indoor mold amounts were low in the schools in our region and no significant correlation was determined between indoor mold amount and the prevalence of these diseases in schools or classrooms. Conclusion: Even though allergic molds are present in schools, the mold-exposure may not be an important predisposing factor for development of allergic and respiratory diseases the schools in our region.

Research paper thumbnail of Çocuklarda Antiepileptik Ilaçların Serum Lipid Profili Üzerine Olan Etkileri Ve Aterosklerozun Erken Belirleyicileri Olan Lipoprotein (A) Düzeyi Ve Karotis Arter Intima Media Kalınlığı Ile Değerlendirilmesi

Amac: Epilepsi kronik bir hastalik olup, uzun sureli tedavinin varligi bu ilaclara bagli yan etki... more Amac: Epilepsi kronik bir hastalik olup, uzun sureli tedavinin varligi bu ilaclara bagli yan etkilerin ortaya cikmasina zemin hazirlamaktadir. Bu calismada antiepileptik ilaclardan valproat ve karbamazepinin ateroskleroz olusumu uzerine olan etkilerini, serum lipid profili, aterosklerozun erken belirleyicileri olan lipoprotein(a) duzeyi ve karotis intima media kalinligi ile arastirilmasi amaclandi. Gerec ve Yontemler: Calismaya Trakya Universitesi Tip Fakultesi Cocuk Noroloji birimimizde Temmuz 2005-Aralik 2006 tarihleri arasinda 2-14 yas araligindaki 27’si Valproat, 12’si Karbamazepin tedavisi alan 39 epileptik hasta ile yas ve cinsiyet acisindan uyumlu 30 saglam cocuk kontrol grubuna alindi. Calisma oncesi tarti, boy ve vucut kitle indeksi degerleri kaydedildi. Tum olgularin tedavi baslangicinda, 12 saatlik aclik sonrasi serum trigliserid, total kolesterol, dusuk dansiteli lipoprotein kolesterol, yuksek dansiteli lipoprotein kolesterol ve lipoprotein(a) tayini icin kan ornekler...

Research paper thumbnail of Trakya bölgesinde çocuklarda görülen zehirlenmeler Orijinal Araştırma

Turk Pediatri Arsivi-turkish Archives of Pediatrics, 2004

Zehirlenmeye yol acan etkenler yasanilan bolgeye toplumun gelenek ve geleneklerine ailenin egitim... more Zehirlenmeye yol acan etkenler yasanilan bolgeye toplumun gelenek ve geleneklerine ailenin egitim duzeyine ve mevsimlere gore degiskenlik gosterebilir Bu calismanin amaci hastanemizde son 5 yil icinde yatirilarak tedavi edilen zehirlenme olgularinin ozelliklerini gozden gecirmektir Ocak 1998 Mayis 2003 tarihleri arasinda zehirlenme tanisi ile yatirilarak tedavi edilen olgularin dosyalari geriye donuk olarak degerlendirildi Olgularin dosya kayitlari incelenerek yas cinsiyet aldigi madde veya ilac karsilasma yolu semptomlar klinik bulgular komplikasyonlar yogun bakim gereksinimi acisindan degerlendirildi Zehirlenme olgularinin tum acil cocuk basvurularina orani 1 6’ydi Iki yuz yirmi yedi olgunun 112’si 49 3 kiz 115’i 50 7 erkekti ve olgularin ortalama yasi 4 5±3 4 1 16 yildi Ilaclar en sik zehirlenme nedeniydi ve ilaclari koroziv maddeler izlemekteydi Olgularin 4 4’unde Pediatrik Yogun Bakim gereksinimi oldu Uc olgu koroziv madde n=2 ve kolsisin n=1 alimi nedeniyle kaybedildi Zehirlen...

Research paper thumbnail of Neonatal Respiratuar Sinsitiyal Virüs Enfeksiyonu

Balkan Medical Journal, 2000

Research paper thumbnail of A Case of Noonan Syndrome Associated with Atrial Septal Defect

Research paper thumbnail of Listeria Monositogenez Menenjitli Bir Olgu Sunumu

Turk Pediatri Arsivi-turkish Archives of Pediatrics, Jun 1, 1999

Yuksek ates kusma uykuya egilim yakinmasiyla getirilen stupor halindeki 3 yasindaki erkek hastada... more Yuksek ates kusma uykuya egilim yakinmasiyla getirilen stupor halindeki 3 yasindaki erkek hastada beyin omurilik sivisi incelemesinde ksantokromi protein yuksekligi lenfosit hakimiyeti saptanmasi uzerine antituberkuloz tedavi baslandi ikinci gunu kaybedilen postmortem BOS kulturunde Listeria Monositogenez ureyen olgu bu yas grubunda Listeriozisin nadir olmasi ve olgunun belirgin bir risk faktoru tasimamasi nedeniyle sunulmustur Anahtar kelimeler: Listeria Monositogenez Menenjit Tuberkuloz

Research paper thumbnail of Cirrhotic Cardiomyopathy

InTech eBooks, Apr 12, 2017

Cirrhotic cardiomyopathy (CCMP) is a functional disorder characterized by electrophysiologic dist... more Cirrhotic cardiomyopathy (CCMP) is a functional disorder characterized by electrophysiologic disturbances and diastolic and/or systolic dysfunction in patients with chronic liver disease, especially those with ascites and portal hypertension. This disorder is a well-defined entity in adults, but pediatric data are limited. Clinical and laboratory findings are generally latent. The diagnostic criteria are prolonged QT on electrocardiography due to metabolic and extrahepatic causes, in addition to some abnormal echocardiography findings. If echocardiographic findings are normal and only specific prolonged QT is present, this disorder is named as "latent CCMP"; otherwise, it is "manifest CCMP." This disorder is important because it may lead to problems such as cardiac failure and dysrhythmia before or after liver transplantation. Moreover, it may worsen the prognosis.