Debora Dessì - Academia.edu (original) (raw)
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Universidad Nacional de Colombia (National University of Colombia)
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Papers by Debora Dessì
ACS applied polymer materials, Jun 14, 2024
Algal research, Apr 1, 2024
Physiological Research, Dec 31, 2022
Wound healing is a dynamic process involving different cell types with distinct roles according t... more Wound healing is a dynamic process involving different cell types with distinct roles according to the stages of healing. Fibroblasts and stem cells actively participate in tissue regeneration. A proper stimulation could contribute to enhance wound healing processes. Helichrysum italicum (H. italicum) is a medical plant well described for its pharmacological, antimicrobial, and anti-inflammatory activities. Aim of the present work was to examine the effect of the hydrolate derivate from H. italicum on stem cells isolated from skin and fibroblasts in vitro in presence or absence of tissue damage. The viability and proliferation of all cell types cultured in different conditions were analyzed by MTT and BrdU assays. Cell proliferation after wound was analyzed with scratch test. Also, the expression of the main genes involved in tissue repair was evaluated by RT-qPCR analysis. Here we describe the capability of hydrolate of H. italicum to promote tissue regeneration after scratch test both in stem cells and in fibroblasts. Moreover, the gene expression analysis revealed that, hydrolate of H. italicum is also able to enhance stemness related. In conclusion our results are encouraging, highlighting novel regenerative properties of hydrolate of H. italicum and paving the way for future application of this wasting product in accelerating wound healing.
Foods, 2022
Potato is a staple food crop and an important source of dietary energy. Its tubers contain severa... more Potato is a staple food crop and an important source of dietary energy. Its tubers contain several essential amino acids, vitamins, minerals and phytochemicals that contribute to the nutritional value of this important product. Recently, scientific interest has focused on purple and red potatoes that, due to the presence of anthocyanins, may be considered as natural powerful functional food. The aim of this study was to evaluate the characteristics of pigmented varieties, the types of anthocyanins accumulated and the level of both beneficial phytochemicals (vitamin C and chlorogenic acids, CGAs) and anti-nutritional compounds (glycoalkaloids) following various cooking methods. The analyses described the presence of a mix of several acylated anthocyanins in pigmented tubers along with high level of CGA. The amount of antioxidants was differently affected by heat treatments according to the type of molecule and the cooking methods used. In some cases, the beneficial compounds were mad...
ACS applied polymer materials, Jun 14, 2024
Algal research, Apr 1, 2024
Physiological Research, Dec 31, 2022
Wound healing is a dynamic process involving different cell types with distinct roles according t... more Wound healing is a dynamic process involving different cell types with distinct roles according to the stages of healing. Fibroblasts and stem cells actively participate in tissue regeneration. A proper stimulation could contribute to enhance wound healing processes. Helichrysum italicum (H. italicum) is a medical plant well described for its pharmacological, antimicrobial, and anti-inflammatory activities. Aim of the present work was to examine the effect of the hydrolate derivate from H. italicum on stem cells isolated from skin and fibroblasts in vitro in presence or absence of tissue damage. The viability and proliferation of all cell types cultured in different conditions were analyzed by MTT and BrdU assays. Cell proliferation after wound was analyzed with scratch test. Also, the expression of the main genes involved in tissue repair was evaluated by RT-qPCR analysis. Here we describe the capability of hydrolate of H. italicum to promote tissue regeneration after scratch test both in stem cells and in fibroblasts. Moreover, the gene expression analysis revealed that, hydrolate of H. italicum is also able to enhance stemness related. In conclusion our results are encouraging, highlighting novel regenerative properties of hydrolate of H. italicum and paving the way for future application of this wasting product in accelerating wound healing.
Foods, 2022
Potato is a staple food crop and an important source of dietary energy. Its tubers contain severa... more Potato is a staple food crop and an important source of dietary energy. Its tubers contain several essential amino acids, vitamins, minerals and phytochemicals that contribute to the nutritional value of this important product. Recently, scientific interest has focused on purple and red potatoes that, due to the presence of anthocyanins, may be considered as natural powerful functional food. The aim of this study was to evaluate the characteristics of pigmented varieties, the types of anthocyanins accumulated and the level of both beneficial phytochemicals (vitamin C and chlorogenic acids, CGAs) and anti-nutritional compounds (glycoalkaloids) following various cooking methods. The analyses described the presence of a mix of several acylated anthocyanins in pigmented tubers along with high level of CGA. The amount of antioxidants was differently affected by heat treatments according to the type of molecule and the cooking methods used. In some cases, the beneficial compounds were mad...