Edgar Mesquita - Academia.edu (original) (raw)
Papers by Edgar Mesquita
Journal of Clinical Medicine Research, Sep 1, 2022
Background: Frailty is a common geriatric syndrome, associated with adverse clinical outcomes. Ne... more Background: Frailty is a common geriatric syndrome, associated with adverse clinical outcomes. Nevertheless, studies about frailty in continuous care units are scarce. In this way, this study aimed to assess frailty in older patients admitted in convalescence units (CUs) and analyze its association with demographic, social and clinical characteristics. Methods: This cross-sectional study included older patients admitted in eight CUs of the Integrated Continued Care National Network in Northern Portugal. Exclusion criteria were: total ≤ 11 in Glasgow coma scale, < 10 in mini-mental state examination or being unable to communicate. A comprehensive protocol was administered to assess health-related and lifestyle characteristics, comorbidity, dependence on activities of daily living (ADL), depressive and anxiety symptoms, cognition, and socio-familial risk. Frailty was assessed by Tilburg frailty indicator (TFI). Results: A sample of 165 patients was included (median age = 77; 65% female), with 80% classified as frail, mostly women (P = 0.002), widowed (P = 0.016), shorter (P = 0.005), feeling more tired (P < 0.005) and with less energy (P < 0.005). Also, these patients reported more vision problems (P = 0.006), difficulties in walking (P = 0.022) and climbing stairs (P = 0.029), pain (P = 0.004), falls (P = 0.046), non-alcohol use (P = 0.043) and non-physical activity (P = 0.032). Frail patients had a higher number of previous hospitalizations (P = 0.018), comorbidity (P = 0.006), dependence on instrumental (P < 0.001) and basic (P = 0.006; P < 0.001) ADL, depressive (P < 0.001) and anxiety (P = 0.002) symptoms. After adjusting for covariates, frailty was associated with females (adjusted odds ratio (aOR) = 4.45, P = 0.011), vascular disease (aOR = 4.40, P = 0.040), vision problems (aOR = 10.85, P < 0.001), high dependency on instrumental ADL (aOR = 0.74, P = 0.002), and depressive symptoms (aOR = 1.37, P = 0.001). Conclusions: Frailty is high among older patients in CUs, particularly in females, with vascular disease, vision problems, instrumental ADL dependence and depressive symptoms. Thus, frailty should be screened, and preventive and therapeutic measures should be considered for those at high risk, in order to minimize possible negative consequences.
Research and practice in thrombosis and haemostasis, 2021
Muitas são as evidências de que o sucesso no Ensino Superior depende muito dos métodos e aptidões... more Muitas são as evidências de que o sucesso no Ensino Superior depende muito dos métodos e aptidões de estudo que os alunos utilizam. Nesse intuito, o presente trabalho pretende adaptar e validar a Escala de Competências e Métodos de Estudo no Ensino Superior para a população angolana. A amostra foi constituída por 286 alunos, de ambos os géneros, com médias de idade de 22.58 anos (DP=4.65), que frequentavam os primeiros anos das licenciaturas de um Instituto Superior em Angola. O instrumento de avaliação utilizado foi a Escala de Competências de Métodos de Estudo (ECME-ES), com escala tipo Likert, constituída na sua versão final por 47 itens e na versão original 63 itens. Os resultados indicaram que esta escala (ECME-ES), constituída por seis subescalas, apresentou como resultados médios mais elevados, por ordem decrescente, as seguintes dimensões: (I) Motivação, (II) Compreensão, (III) Avaliação, (IV) Organização diária da área de estudo, (V) Gestão do Tempo e VI. Procrastinação. Os...
Acta Médica Portuguesa
Introduction: Following the outbreak of the disease caused by the novel coronavirus it was necess... more Introduction: Following the outbreak of the disease caused by the novel coronavirus it was necessary to increase the non-face-to-face care activity through alternative means such as teleconsultation in primary health care. The adjustment to a type of remote consultation could have generated anxiety among family physicians. The main aim of the present study was to develop and validate a scale to assess the anxiety of family physicians during teleconsultation. Material and Methods: Observational, cross-sectional study involving a sample of family physicians working in Portugal. An online survey that evaluated anxiety in teleconsultation was developed.Results: A total of 359 valid responses were included in an exploratory factor analysis, after determining the number of factors to retain. A four-factor structure was detected with loadings ranging overall, from 0.44 to 0.98. Correlations between factors ranged from 0.42 to 0.58. Exploratory factor analysis results varied between good an...
Academic Journal of Interdisciplinary Studies, May 5, 2022
Human beings are curious, intrinsically motivated and often look for sensations based on goals an... more Human beings are curious, intrinsically motivated and often look for sensations based on goals and plans to overcome the difficulties and challenges that arise towards happiness, wellbeing, and personal growth. The present study aims to understand the usefulness and practicality of a therapeutic notepad, which is composed of inspiring quotes and tasks underlying happiness and well-being. 111 young people and adults, aged between 18 and 58 years (M= 21.81; SD= 5.34) participated in this study, being 47.3% male individuals and 52.7% female individuals. First, a sociodemographic questionnaire was applied to collect personal data; then was administered the Psychological Well-Being Manifestations Scale (Échelle de Mesure des Manifestations du Bien-Être Psychologique) which translates into a response instrument five-point likert type with five subscales including happiness. Finally, a semistructured interview was applied to understand the functionality of the therapeutic agenda. The results showed, both qualitatively and quantitatively, that the notepad can be assumed as an agent that promotes happiness and well-being as well as reducing the negative mood of individuals. This study focuses on the importance of well-being and happiness in the daily lives of individuals. This is an important contribution, as it allows to gauge that the notepad leads to positive and motivating results when applied.
International Journal of Health Science
All content in this magazine is licensed under a Creative Commons Attribution License. Attributio... more All content in this magazine is licensed under a Creative Commons Attribution License. Attribution-Non-Commercial-Non-Derivatives 4.0 International (CC BY-NC-ND 4.0).
A psicologia e a exploração da percepção, cognição, emoção e personalidade 2, 2021
A psicologia no Brasil: Teoria e pesquisa, 2022
We present 10 tables with different, related data. Table 1 is the result of an extensive narrativ... more We present 10 tables with different, related data. Table 1 is the result of an extensive narrative literature review depicting published national secular suicide trends extending by at least a century. Table 2 pinpoints all reforms in the statistical national system by year, period and political regimen since 1886. In Table 3, we relate different consecutive versions of international classification of diseases and causes of death, by year of international approval and periodic implementation in the national statistical system, also by period of political regimen, depicting periods when different data was made accessible (sex, age), when categories of causes of external death begun to be collected (total external, suicide, accidents, undetermined), and types of dates were apt to be estimated (eg., crude death rates, age-standardised death rates, age-specific death rates); Table 3 also shows a cumulative index of years and attributes bibliographic primary sources for each line of data...
As Catirinas são homens vestidos de mulheres e os Mateus vestem-se com roupas engraçadas (chapéu ... more As Catirinas são homens vestidos de mulheres e os Mateus vestem-se com roupas engraçadas (chapéu grande e bengala ou pandeiro), circulando o jogo dramático dos dois partidos e, geralmente, ironizando o clima de luta criado pelos mesmos. Estes personagens que aparentam fragmentos desconexos da encenação também são os que mais aproveitam para pedir esmolas aos espectadores enquanto os guerreiros estão se digladiando ou preparando-se para a guerra. (REIS, Damian, 1997) in: Etnocenologia: textos selecionados. Greiner, Christine; Bião, Armindo (org.), 1999, p. 121. Personagens surpresas para mim desde que eu passei a ter contatos com os presépios da atualidade, Mateus e Catita ou Catirina 1 são dois personagens recorrentes dos festejos folclóricos brasileiros, especialmente nos festejos natalinos, como brincantes ativos nos grupos de Reis. É sabido que os reisados compõem e cantam músicas direcionadas ao poder, pois, são representativas de "lideranças políticas" seguindo uma tr...
Suicidal behaviors of children and young people are a major public health concern. In Portugal, t... more Suicidal behaviors of children and young people are a major public health concern. In Portugal, the increasing awareness of this problem is well reflected by the implementation of the first national suicide prevention plan from 2013 to 2017. One of its main goals is to increase information and education about mental health in schools. By use of a setting approach and empowerment strategies, we pretend to develop the teachers' and educators' skills to adequately handle with new situations. To analyse the psychometric characteristics of instrument designed to assess mental health of Portuguese teachers. The instrument has been developed to monitor the learning results of teacher training in a massive open online course (MOOC). Teachers (n=1144) were recruited online by using a link from the platform Qualtrics. Informed consent was obtained before enrolment in the study. Items of the questionnaire Mental Health Literacy QLSM were developed after a screening of literature and ex...
Suicidal behaviors of children and young people are a major public health concern. In Portugal, t... more Suicidal behaviors of children and young people are a major public health concern. In Portugal, the increasing awareness of this problem is well reflected by the implementation of the first national suicide prevention plan from 2013 to 2017. One of its main goals is to increase information and education about mental health in schools. By use of a setting approach and empowerment strategies, we pretend to develop the teachers’ and educators’ skills to adequately handle with new situations. To analyse the psychometric characteristics of instrument designed to assess mental health of Portuguese teachers. The instrument has been developed to monitor the learning results of teacher training in a massive open online course (MOOC). Teachers (n=1144) were recruited online by using a link from the platform Qualtrics. Informed consent was obtained before enrolment in the study. Items of the questionnaire Mental Health Literacy QLSM were developed after a screening of literature and explorator...
Revista de Enfermagem Referência, Dec 12, 2017
Enquadramento: A adaptação e validação da escala Adapted Illness Intrusiveness Ratings Scale é um... more Enquadramento: A adaptação e validação da escala Adapted Illness Intrusiveness Ratings Scale é um estudo de tradução e medição das suas propriedades psicométricas, permitindo avaliar a sua validade e confiabilidade. Procedemos à sua adaptação e validação devido ao facto de não ter sido ainda realizado no contexto português. Objetivos: Tradução e validação da escala. Metodologia: O instrumento foi aplicado a uma amostra de conveniência de 271 pessoas com doença crónica, com idades compreendidas entre os 18 e os 65 anos residentes em Lisboa. Para avaliar as suas propriedades psicométricas recorreu-se a análise fatorial exploratória. Confirmou-se o modelo proposto pelo autor através da análise fatorial confirmatória. Resultados: Da análise fatorial com rotação Varimax resultaram 3 dimensões (Atividades Instrumentais, Intimidade, Relacionamento e Desenvolvimento Pessoal) explicando 73,24% da variância total. A escala revelou uma consistência interna global de 0,92. Conclusão: A escala mostrou ser um instrumento fiável, válido e útil para medir a perceção da interferência da doença crónica na vida das pessoas. Palavras-chave: doença crónica; perfil de impacto da doença; avaliação em enfermagem
Objective: While Parkinson’s disease (PD) has traditionally been described as a movement disorder... more Objective: While Parkinson’s disease (PD) has traditionally been described as a movement disorder, there is growing evidence of disruption in emotion information processing as ociated with the disease. The aim of this study was to investigate whether there are specific electroencephalographic (EEG) characteristics that discriminate PD patients and normal controls during emotion information processing. Method: EEG recordings from 14 scalp sites were collected from 20 PD patients and 30 agematched normal controls. Multimodal (audio-visual) stimuli were presented to evoke s pecific targeted emotional states such as happiness, sadness, fear, anger, surprise and disgust. Absolute and relative power, frequency and asymmetry measures derived from spectral ly analyzed EEGs were subjected to repeated ANOVA measures for group comparisons as well a to discriminate function analysis to examine their utility as classification indices. In a ddition, subjective ratings were obtained for the used e...
Journal of Affective Disorders
Acta Médica Portuguesa
Introduction: This study aims to describe the translation and adaptation of the European Portugue... more Introduction: This study aims to describe the translation and adaptation of the European Portuguese Clinical Frailty Scale and assess its convergent validity and test-retest reliability.Material and Methods: This validation study included a sample of elderly people admitted in two convalescence units from the National Network of Integrated Continuous Care in Northern Portugal and followed in two outpatient clinics of social solidarity institutions. Convergent validity of the scale was evaluated, against Tilburg Frailty Indicator. Test-retest reliability, sensitivity and specificity were assessed.Results: Overall, 51 patients were included (mean age = 78 years old). The Clinical Frailty Scale identified 43.1% patients with frailty. Kappa values for test-retest reliability (non-frail/frail) was 1.00. The intraclass correlation coefficient for the 9-point total scale was 0.999. A correlation between Clinical Frailty Scale and Tilburg Frailty Indicator was also found (rs = 0.683; p <...
Blood
1435 Introduction: The response to AML treatment is very heterogeneous and relapse risk is high. ... more 1435 Introduction: The response to AML treatment is very heterogeneous and relapse risk is high. Hematogones (HG) are B lymphoid cell precursors present in all individuals. HG absolute count grows after chemotherapy, during medullar recovery and it seems to be related to prognosis. Objectives: Determination of HG number in AML patients with intermediate-risk karyotype, with complete response (CR). Determine prognostic value for HG number in these patients. Methods: Retrospective analysis of 148 patients with non promyelocytic AML, treated with “7+3” chemotherapy induction, followed in our centre, from 1998 to 2011. HG quantification was executed after induction chemotherapy, with flow cytometry pannel (4 colours - CD34, CD10, CD19, CD20 e CD45) in blood marrow samples in patients with CR, according to Cheson et al. (JCO 2003). The patients characteristics were compared with a X2test for binary variables and a Mann-Whitney test for continuous variables. Survival was plotted with Kapl...
Blood
BACKGROUND: The best treatment strategy in patients with relapsed Follicular Lymphoma (FL) remain... more BACKGROUND: The best treatment strategy in patients with relapsed Follicular Lymphoma (FL) remains controversial. The incorporation of rituximab (R) in the 1st line chemotherapy (CT) regimen and in treatment relapse resulted in better progression-free survival (PFS) but the benefit in overall survival (OS) was observed in only one trial (Hiddemann W. et al, Blood 2006). Hematopoietic stem cell transplant (HSCT) is the only treatment potentially curative, although the ideal time for its implementation remains undefined. AIM: Evaluation of the best treatment strategy and the impact of HSCT in PFS and OS in patients with relapsed FL. METHODS: Retrospective study including 85 patients with relapsed FL followed at a cancer care center between 2000-2012. Selection criteria: treatment naïve patients with the diagnosis of FL; absence of histological transformation at diagnosis and/or during the 1st line treatment. Survival analysis using the Kaplan-Meier method. Type of response defined acc...
Journal of Clinical Medicine Research, Sep 1, 2022
Background: Frailty is a common geriatric syndrome, associated with adverse clinical outcomes. Ne... more Background: Frailty is a common geriatric syndrome, associated with adverse clinical outcomes. Nevertheless, studies about frailty in continuous care units are scarce. In this way, this study aimed to assess frailty in older patients admitted in convalescence units (CUs) and analyze its association with demographic, social and clinical characteristics. Methods: This cross-sectional study included older patients admitted in eight CUs of the Integrated Continued Care National Network in Northern Portugal. Exclusion criteria were: total ≤ 11 in Glasgow coma scale, < 10 in mini-mental state examination or being unable to communicate. A comprehensive protocol was administered to assess health-related and lifestyle characteristics, comorbidity, dependence on activities of daily living (ADL), depressive and anxiety symptoms, cognition, and socio-familial risk. Frailty was assessed by Tilburg frailty indicator (TFI). Results: A sample of 165 patients was included (median age = 77; 65% female), with 80% classified as frail, mostly women (P = 0.002), widowed (P = 0.016), shorter (P = 0.005), feeling more tired (P < 0.005) and with less energy (P < 0.005). Also, these patients reported more vision problems (P = 0.006), difficulties in walking (P = 0.022) and climbing stairs (P = 0.029), pain (P = 0.004), falls (P = 0.046), non-alcohol use (P = 0.043) and non-physical activity (P = 0.032). Frail patients had a higher number of previous hospitalizations (P = 0.018), comorbidity (P = 0.006), dependence on instrumental (P < 0.001) and basic (P = 0.006; P < 0.001) ADL, depressive (P < 0.001) and anxiety (P = 0.002) symptoms. After adjusting for covariates, frailty was associated with females (adjusted odds ratio (aOR) = 4.45, P = 0.011), vascular disease (aOR = 4.40, P = 0.040), vision problems (aOR = 10.85, P < 0.001), high dependency on instrumental ADL (aOR = 0.74, P = 0.002), and depressive symptoms (aOR = 1.37, P = 0.001). Conclusions: Frailty is high among older patients in CUs, particularly in females, with vascular disease, vision problems, instrumental ADL dependence and depressive symptoms. Thus, frailty should be screened, and preventive and therapeutic measures should be considered for those at high risk, in order to minimize possible negative consequences.
Research and practice in thrombosis and haemostasis, 2021
Muitas são as evidências de que o sucesso no Ensino Superior depende muito dos métodos e aptidões... more Muitas são as evidências de que o sucesso no Ensino Superior depende muito dos métodos e aptidões de estudo que os alunos utilizam. Nesse intuito, o presente trabalho pretende adaptar e validar a Escala de Competências e Métodos de Estudo no Ensino Superior para a população angolana. A amostra foi constituída por 286 alunos, de ambos os géneros, com médias de idade de 22.58 anos (DP=4.65), que frequentavam os primeiros anos das licenciaturas de um Instituto Superior em Angola. O instrumento de avaliação utilizado foi a Escala de Competências de Métodos de Estudo (ECME-ES), com escala tipo Likert, constituída na sua versão final por 47 itens e na versão original 63 itens. Os resultados indicaram que esta escala (ECME-ES), constituída por seis subescalas, apresentou como resultados médios mais elevados, por ordem decrescente, as seguintes dimensões: (I) Motivação, (II) Compreensão, (III) Avaliação, (IV) Organização diária da área de estudo, (V) Gestão do Tempo e VI. Procrastinação. Os...
Acta Médica Portuguesa
Introduction: Following the outbreak of the disease caused by the novel coronavirus it was necess... more Introduction: Following the outbreak of the disease caused by the novel coronavirus it was necessary to increase the non-face-to-face care activity through alternative means such as teleconsultation in primary health care. The adjustment to a type of remote consultation could have generated anxiety among family physicians. The main aim of the present study was to develop and validate a scale to assess the anxiety of family physicians during teleconsultation. Material and Methods: Observational, cross-sectional study involving a sample of family physicians working in Portugal. An online survey that evaluated anxiety in teleconsultation was developed.Results: A total of 359 valid responses were included in an exploratory factor analysis, after determining the number of factors to retain. A four-factor structure was detected with loadings ranging overall, from 0.44 to 0.98. Correlations between factors ranged from 0.42 to 0.58. Exploratory factor analysis results varied between good an...
Academic Journal of Interdisciplinary Studies, May 5, 2022
Human beings are curious, intrinsically motivated and often look for sensations based on goals an... more Human beings are curious, intrinsically motivated and often look for sensations based on goals and plans to overcome the difficulties and challenges that arise towards happiness, wellbeing, and personal growth. The present study aims to understand the usefulness and practicality of a therapeutic notepad, which is composed of inspiring quotes and tasks underlying happiness and well-being. 111 young people and adults, aged between 18 and 58 years (M= 21.81; SD= 5.34) participated in this study, being 47.3% male individuals and 52.7% female individuals. First, a sociodemographic questionnaire was applied to collect personal data; then was administered the Psychological Well-Being Manifestations Scale (Échelle de Mesure des Manifestations du Bien-Être Psychologique) which translates into a response instrument five-point likert type with five subscales including happiness. Finally, a semistructured interview was applied to understand the functionality of the therapeutic agenda. The results showed, both qualitatively and quantitatively, that the notepad can be assumed as an agent that promotes happiness and well-being as well as reducing the negative mood of individuals. This study focuses on the importance of well-being and happiness in the daily lives of individuals. This is an important contribution, as it allows to gauge that the notepad leads to positive and motivating results when applied.
International Journal of Health Science
All content in this magazine is licensed under a Creative Commons Attribution License. Attributio... more All content in this magazine is licensed under a Creative Commons Attribution License. Attribution-Non-Commercial-Non-Derivatives 4.0 International (CC BY-NC-ND 4.0).
A psicologia e a exploração da percepção, cognição, emoção e personalidade 2, 2021
A psicologia no Brasil: Teoria e pesquisa, 2022
We present 10 tables with different, related data. Table 1 is the result of an extensive narrativ... more We present 10 tables with different, related data. Table 1 is the result of an extensive narrative literature review depicting published national secular suicide trends extending by at least a century. Table 2 pinpoints all reforms in the statistical national system by year, period and political regimen since 1886. In Table 3, we relate different consecutive versions of international classification of diseases and causes of death, by year of international approval and periodic implementation in the national statistical system, also by period of political regimen, depicting periods when different data was made accessible (sex, age), when categories of causes of external death begun to be collected (total external, suicide, accidents, undetermined), and types of dates were apt to be estimated (eg., crude death rates, age-standardised death rates, age-specific death rates); Table 3 also shows a cumulative index of years and attributes bibliographic primary sources for each line of data...
As Catirinas são homens vestidos de mulheres e os Mateus vestem-se com roupas engraçadas (chapéu ... more As Catirinas são homens vestidos de mulheres e os Mateus vestem-se com roupas engraçadas (chapéu grande e bengala ou pandeiro), circulando o jogo dramático dos dois partidos e, geralmente, ironizando o clima de luta criado pelos mesmos. Estes personagens que aparentam fragmentos desconexos da encenação também são os que mais aproveitam para pedir esmolas aos espectadores enquanto os guerreiros estão se digladiando ou preparando-se para a guerra. (REIS, Damian, 1997) in: Etnocenologia: textos selecionados. Greiner, Christine; Bião, Armindo (org.), 1999, p. 121. Personagens surpresas para mim desde que eu passei a ter contatos com os presépios da atualidade, Mateus e Catita ou Catirina 1 são dois personagens recorrentes dos festejos folclóricos brasileiros, especialmente nos festejos natalinos, como brincantes ativos nos grupos de Reis. É sabido que os reisados compõem e cantam músicas direcionadas ao poder, pois, são representativas de "lideranças políticas" seguindo uma tr...
Suicidal behaviors of children and young people are a major public health concern. In Portugal, t... more Suicidal behaviors of children and young people are a major public health concern. In Portugal, the increasing awareness of this problem is well reflected by the implementation of the first national suicide prevention plan from 2013 to 2017. One of its main goals is to increase information and education about mental health in schools. By use of a setting approach and empowerment strategies, we pretend to develop the teachers' and educators' skills to adequately handle with new situations. To analyse the psychometric characteristics of instrument designed to assess mental health of Portuguese teachers. The instrument has been developed to monitor the learning results of teacher training in a massive open online course (MOOC). Teachers (n=1144) were recruited online by using a link from the platform Qualtrics. Informed consent was obtained before enrolment in the study. Items of the questionnaire Mental Health Literacy QLSM were developed after a screening of literature and ex...
Suicidal behaviors of children and young people are a major public health concern. In Portugal, t... more Suicidal behaviors of children and young people are a major public health concern. In Portugal, the increasing awareness of this problem is well reflected by the implementation of the first national suicide prevention plan from 2013 to 2017. One of its main goals is to increase information and education about mental health in schools. By use of a setting approach and empowerment strategies, we pretend to develop the teachers’ and educators’ skills to adequately handle with new situations. To analyse the psychometric characteristics of instrument designed to assess mental health of Portuguese teachers. The instrument has been developed to monitor the learning results of teacher training in a massive open online course (MOOC). Teachers (n=1144) were recruited online by using a link from the platform Qualtrics. Informed consent was obtained before enrolment in the study. Items of the questionnaire Mental Health Literacy QLSM were developed after a screening of literature and explorator...
Revista de Enfermagem Referência, Dec 12, 2017
Enquadramento: A adaptação e validação da escala Adapted Illness Intrusiveness Ratings Scale é um... more Enquadramento: A adaptação e validação da escala Adapted Illness Intrusiveness Ratings Scale é um estudo de tradução e medição das suas propriedades psicométricas, permitindo avaliar a sua validade e confiabilidade. Procedemos à sua adaptação e validação devido ao facto de não ter sido ainda realizado no contexto português. Objetivos: Tradução e validação da escala. Metodologia: O instrumento foi aplicado a uma amostra de conveniência de 271 pessoas com doença crónica, com idades compreendidas entre os 18 e os 65 anos residentes em Lisboa. Para avaliar as suas propriedades psicométricas recorreu-se a análise fatorial exploratória. Confirmou-se o modelo proposto pelo autor através da análise fatorial confirmatória. Resultados: Da análise fatorial com rotação Varimax resultaram 3 dimensões (Atividades Instrumentais, Intimidade, Relacionamento e Desenvolvimento Pessoal) explicando 73,24% da variância total. A escala revelou uma consistência interna global de 0,92. Conclusão: A escala mostrou ser um instrumento fiável, válido e útil para medir a perceção da interferência da doença crónica na vida das pessoas. Palavras-chave: doença crónica; perfil de impacto da doença; avaliação em enfermagem
Objective: While Parkinson’s disease (PD) has traditionally been described as a movement disorder... more Objective: While Parkinson’s disease (PD) has traditionally been described as a movement disorder, there is growing evidence of disruption in emotion information processing as ociated with the disease. The aim of this study was to investigate whether there are specific electroencephalographic (EEG) characteristics that discriminate PD patients and normal controls during emotion information processing. Method: EEG recordings from 14 scalp sites were collected from 20 PD patients and 30 agematched normal controls. Multimodal (audio-visual) stimuli were presented to evoke s pecific targeted emotional states such as happiness, sadness, fear, anger, surprise and disgust. Absolute and relative power, frequency and asymmetry measures derived from spectral ly analyzed EEGs were subjected to repeated ANOVA measures for group comparisons as well a to discriminate function analysis to examine their utility as classification indices. In a ddition, subjective ratings were obtained for the used e...
Journal of Affective Disorders
Acta Médica Portuguesa
Introduction: This study aims to describe the translation and adaptation of the European Portugue... more Introduction: This study aims to describe the translation and adaptation of the European Portuguese Clinical Frailty Scale and assess its convergent validity and test-retest reliability.Material and Methods: This validation study included a sample of elderly people admitted in two convalescence units from the National Network of Integrated Continuous Care in Northern Portugal and followed in two outpatient clinics of social solidarity institutions. Convergent validity of the scale was evaluated, against Tilburg Frailty Indicator. Test-retest reliability, sensitivity and specificity were assessed.Results: Overall, 51 patients were included (mean age = 78 years old). The Clinical Frailty Scale identified 43.1% patients with frailty. Kappa values for test-retest reliability (non-frail/frail) was 1.00. The intraclass correlation coefficient for the 9-point total scale was 0.999. A correlation between Clinical Frailty Scale and Tilburg Frailty Indicator was also found (rs = 0.683; p <...
Blood
1435 Introduction: The response to AML treatment is very heterogeneous and relapse risk is high. ... more 1435 Introduction: The response to AML treatment is very heterogeneous and relapse risk is high. Hematogones (HG) are B lymphoid cell precursors present in all individuals. HG absolute count grows after chemotherapy, during medullar recovery and it seems to be related to prognosis. Objectives: Determination of HG number in AML patients with intermediate-risk karyotype, with complete response (CR). Determine prognostic value for HG number in these patients. Methods: Retrospective analysis of 148 patients with non promyelocytic AML, treated with “7+3” chemotherapy induction, followed in our centre, from 1998 to 2011. HG quantification was executed after induction chemotherapy, with flow cytometry pannel (4 colours - CD34, CD10, CD19, CD20 e CD45) in blood marrow samples in patients with CR, according to Cheson et al. (JCO 2003). The patients characteristics were compared with a X2test for binary variables and a Mann-Whitney test for continuous variables. Survival was plotted with Kapl...
Blood
BACKGROUND: The best treatment strategy in patients with relapsed Follicular Lymphoma (FL) remain... more BACKGROUND: The best treatment strategy in patients with relapsed Follicular Lymphoma (FL) remains controversial. The incorporation of rituximab (R) in the 1st line chemotherapy (CT) regimen and in treatment relapse resulted in better progression-free survival (PFS) but the benefit in overall survival (OS) was observed in only one trial (Hiddemann W. et al, Blood 2006). Hematopoietic stem cell transplant (HSCT) is the only treatment potentially curative, although the ideal time for its implementation remains undefined. AIM: Evaluation of the best treatment strategy and the impact of HSCT in PFS and OS in patients with relapsed FL. METHODS: Retrospective study including 85 patients with relapsed FL followed at a cancer care center between 2000-2012. Selection criteria: treatment naïve patients with the diagnosis of FL; absence of histological transformation at diagnosis and/or during the 1st line treatment. Survival analysis using the Kaplan-Meier method. Type of response defined acc...