Aldo Gatto - Academia.edu (original) (raw)
Papers by Aldo Gatto
Trials, 2012
Background: Multi-element interventions for first-episode psychosis (FEP) are promising, but have... more Background: Multi-element interventions for first-episode psychosis (FEP) are promising, but have mostly been conducted in non-epidemiologically representative samples, thereby raising the risk of underestimating the complexities involved in treating FEP in 'real-world' services. Methods/Design: The Psychosis early Intervention and Assessment of Needs and Outcome (PIANO) trial is part of a larger research program (Genetics, Endophenotypes and Treatment: Understanding early Psychosis-GET UP) which aims to compare, at 9 months, the effectiveness of a multi-component psychosocial intervention versus treatment as usual (TAU) in a large epidemiologically based cohort of patients with FEP and their family members recruited from all public community mental health centers (CMHCs) located in two entire regions of Italy (Veneto and Emilia Romagna), and in the cities of Florence, Milan and Bolzano. The GET UP PIANO trial has a pragmatic cluster randomized controlled design. The randomized units (clusters) are the CMHCs, and the units of observation are the centers' patients and their family members. Patients in the experimental group will receive TAU plus: 1) cognitive behavioral therapy sessions, 2) psycho-educational sessions for family members, and 3) case management. Patient enrolment will take place over a 1-year period. Several psychopathological, psychological, functioning, and service use variables will be assessed at baseline and follow-up. The primary outcomes are: 1) change from baseline to follow-up in positive and negative symptoms' severity and subjective appraisal; 2) relapse occurrences between baseline and follow-up, that is, episodes resulting in admission and/or any case-note records of re-emergence of positive psychotic symptoms. The expected number of recruited patients is about 400, and that of relatives about 300.
by C. Bonetto, Stefano Torresani, Carla Cremonese, Paolo Scocco, Katia Santi, Veronica Marinelli, Renato Magnabosco, Spyridon Zotos, Ileana Boggian, enrico ceccato, Rosa Dall'Agnola, Raffaello Conti, Marta Zenari, Giovanni Austoni, Aldo Gatto, Anna Dominoni, Mauro Scabbio, Roberto Marchioro, Walter Paganelli, Maria Piscitelli, Gregorio Reggiani, Damiano Suzzi, Stefano Cenni, Glenda Marzola, Carla Leoni, Roberta Cellesi, Virginia Brambilla, Anita Montanari, M. Pellizzer, Silvia Azzali, Luca Bensi, Davide Cappellari, Nadia Campagnola, Laura Mairaghi, Sara Malak, Luca Mesiano, Manuela Soave, Natascia Brondino, Alessandra Bergami, Donatella Bolzon, Karin Furlato, Sara Garlassi, Alessandro Gavarini, Fabio Macchetti, Stefano Totaro, and Barbara Bianchi
TRIALS, 2012
Background: Multi-element interventions for first-episode psychosis (FEP) are promising, but have... more Background: Multi-element interventions for first-episode psychosis (FEP) are promising, but have mostly been conducted in non-epidemiologically representative samples, thereby raising the risk of underestimating the complexities involved in treating FEP in 'real-world' services. Methods/Design: The Psychosis early Intervention and Assessment of Needs and Outcome (PIANO) trial is part of a larger research program (Genetics, Endophenotypes and Treatment: Understanding early Psychosis -GET UP) which aims to compare, at 9 months, the effectiveness of a multi-component psychosocial intervention versus treatment as usual (TAU) in a large epidemiologically based cohort of patients with FEP and their family members recruited from all public community mental health centers (CMHCs) located in two entire regions of Italy (Veneto and Emilia Romagna), and in the cities of Florence, Milan and Bolzano. The GET UP PIANO trial has a pragmatic cluster randomized controlled design. The randomized units (clusters) are the CMHCs, and the units of observation are the centers' patients and their family members. Patients in the experimental group will receive TAU plus: 1) cognitive behavioral therapy sessions, 2) psycho-educational sessions for family members, and 3) case management. Patient enrolment will take place over a 1-year period. Several psychopathological, psychological, functioning, and service use variables will be assessed at baseline and follow-up. The primary outcomes are: 1) change from baseline to follow-up in positive and negative symptoms' severity and subjective appraisal; 2) relapse occurrences between baseline and follow-up, that is, episodes resulting in admission and/or any case-note records of re-emergence of positive psychotic symptoms. The expected number of recruited patients is about 400, and that of relatives about 300.
Trials, 2012
Background: Multi-element interventions for first-episode psychosis (FEP) are promising, but have... more Background: Multi-element interventions for first-episode psychosis (FEP) are promising, but have mostly been conducted in non-epidemiologically representative samples, thereby raising the risk of underestimating the complexities involved in treating FEP in 'real-world' services. Methods/Design: The Psychosis early Intervention and Assessment of Needs and Outcome (PIANO) trial is part of a larger research program (Genetics, Endophenotypes and Treatment: Understanding early Psychosis-GET UP) which aims to compare, at 9 months, the effectiveness of a multi-component psychosocial intervention versus treatment as usual (TAU) in a large epidemiologically based cohort of patients with FEP and their family members recruited from all public community mental health centers (CMHCs) located in two entire regions of Italy (Veneto and Emilia Romagna), and in the cities of Florence, Milan and Bolzano. The GET UP PIANO trial has a pragmatic cluster randomized controlled design. The randomized units (clusters) are the CMHCs, and the units of observation are the centers' patients and their family members. Patients in the experimental group will receive TAU plus: 1) cognitive behavioral therapy sessions, 2) psycho-educational sessions for family members, and 3) case management. Patient enrolment will take place over a 1-year period. Several psychopathological, psychological, functioning, and service use variables will be assessed at baseline and follow-up. The primary outcomes are: 1) change from baseline to follow-up in positive and negative symptoms' severity and subjective appraisal; 2) relapse occurrences between baseline and follow-up, that is, episodes resulting in admission and/or any case-note records of re-emergence of positive psychotic symptoms. The expected number of recruited patients is about 400, and that of relatives about 300.
by C. Bonetto, Stefano Torresani, Carla Cremonese, Paolo Scocco, Katia Santi, Veronica Marinelli, Renato Magnabosco, Spyridon Zotos, Ileana Boggian, enrico ceccato, Rosa Dall'Agnola, Raffaello Conti, Marta Zenari, Giovanni Austoni, Aldo Gatto, Anna Dominoni, Mauro Scabbio, Roberto Marchioro, Walter Paganelli, Maria Piscitelli, Gregorio Reggiani, Damiano Suzzi, Stefano Cenni, Glenda Marzola, Carla Leoni, Roberta Cellesi, Virginia Brambilla, Anita Montanari, M. Pellizzer, Silvia Azzali, Luca Bensi, Davide Cappellari, Nadia Campagnola, Laura Mairaghi, Sara Malak, Luca Mesiano, Manuela Soave, Natascia Brondino, Alessandra Bergami, Donatella Bolzon, Karin Furlato, Sara Garlassi, Alessandro Gavarini, Fabio Macchetti, Stefano Totaro, and Barbara Bianchi
TRIALS, 2012
Background: Multi-element interventions for first-episode psychosis (FEP) are promising, but have... more Background: Multi-element interventions for first-episode psychosis (FEP) are promising, but have mostly been conducted in non-epidemiologically representative samples, thereby raising the risk of underestimating the complexities involved in treating FEP in 'real-world' services. Methods/Design: The Psychosis early Intervention and Assessment of Needs and Outcome (PIANO) trial is part of a larger research program (Genetics, Endophenotypes and Treatment: Understanding early Psychosis -GET UP) which aims to compare, at 9 months, the effectiveness of a multi-component psychosocial intervention versus treatment as usual (TAU) in a large epidemiologically based cohort of patients with FEP and their family members recruited from all public community mental health centers (CMHCs) located in two entire regions of Italy (Veneto and Emilia Romagna), and in the cities of Florence, Milan and Bolzano. The GET UP PIANO trial has a pragmatic cluster randomized controlled design. The randomized units (clusters) are the CMHCs, and the units of observation are the centers' patients and their family members. Patients in the experimental group will receive TAU plus: 1) cognitive behavioral therapy sessions, 2) psycho-educational sessions for family members, and 3) case management. Patient enrolment will take place over a 1-year period. Several psychopathological, psychological, functioning, and service use variables will be assessed at baseline and follow-up. The primary outcomes are: 1) change from baseline to follow-up in positive and negative symptoms' severity and subjective appraisal; 2) relapse occurrences between baseline and follow-up, that is, episodes resulting in admission and/or any case-note records of re-emergence of positive psychotic symptoms. The expected number of recruited patients is about 400, and that of relatives about 300.