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Papers by Gholamreza pourshahbazi

Research paper thumbnail of Human Anti-Toxoplasma Antibodies Attach Strongly to Breast Cancer Cells

International Journal of Cancer Management

Background: Toxoplasma gondii (T. gondii) is the most common intracellular parasite in the human ... more Background: Toxoplasma gondii (T. gondii) is the most common intracellular parasite in the human population. The anti-cancer effect of these parasites has been shown, which may be due to the presence of common antigens between the parasite and cancer cells. Objectives: In this work, the reaction of Toxoplasma-positive human sera and Toxoplasma-negative human sera with cell surfaces of 4T1 and MCF7 cell lines have been investigated. Methods: 4T1 and MCF7 cells were harvested from cell cultures and treated with either human Toxoplasma Positive or negative sera. The reaction of the sera was then detected using the flow cytometry method. Results: Toxoplasma-positive sera but not Toxoplasma-negative ones reacted very sharply with both breast cancer cell lines. Conclusions: Anti-T. gondii antibodies strongly react with breast cancer cells. These antibodies may be used for selective cancer immunotherapy in the future.

Research paper thumbnail of Fauna and the distribution of mosquitoes (Diptera: Culicidae) in Chahar Mahal and Bakhtiari Province, 2011-2012

Background and aims: Mosquitoes constitute a large family in Diptera and because of their ability... more Background and aims: Mosquitoes constitute a large family in Diptera and because of their ability in the transmission of a wide range of pathogens are of great public health and medical importance. This study was carried out to refresh our current knowledge on the fauna and the distribution of indigenous mosquitoes in Chahar Mahal and Bakhtiari Province. Methods: This descriptive, cross-sectional study was carried out during the summers of 2011 and 2012 in the all districts of Chahar Mahal and Bakhtiari Province. Larval specimens were collected by the standard dipping method and identified with the aid of valid keys. Identification data plus the geographical information of the collection sites were entered in ArcGIS 10.0 software to draw the map of distribution for each mosquito species. Results: In this investigation, 8335 larvae were collected from 92 larval habitats belonged to 18 mosquito species including Culiseta longiareolata Macquart, Cs. subochrea Edwards, Ochlerotattus cas...

Research paper thumbnail of Toxocara infection in dogs and cats in Isfahan province of Iran in 2021

Advanced Biomedical Research

Research paper thumbnail of Genotyping of Trichomonas vaginalis isolates from women in Shahrekord city (Southwestern Iran)

ABI Genetika, 2017

Trichomonas vaginalis is a causative agent of vaginitis in female and urethritis in men. It is pr... more Trichomonas vaginalis is a causative agent of vaginitis in female and urethritis in men. It is primarily transmitted by sexually route. It is known that each geographical area has its own set of Trichomonas vaginalis strain. Parasite strains in each region have its specific characterizations and different strains of the parasite are able to cause various diseases with the acuity and severity. The aim of this study was to determine the genotyping of Trichomonas vaginalis strains in the Shahrekord city (Chaharmahal Va Bakhtiari province, southwest Iran). A total of 1725 vaginal samples were taken from clinically suspected women for Trichomonas vaginalis infection and 21 specimens were diagnosed as positive by direct smear wet mount and culture repeated 1060

Research paper thumbnail of Human Anti-Toxoplasma Antibodies Attach Strongly to Breast Cancer Cells

International Journal of Cancer Management

Background: Toxoplasma gondii (T. gondii) is the most common intracellular parasite in the human ... more Background: Toxoplasma gondii (T. gondii) is the most common intracellular parasite in the human population. The anti-cancer effect of these parasites has been shown, which may be due to the presence of common antigens between the parasite and cancer cells. Objectives: In this work, the reaction of Toxoplasma-positive human sera and Toxoplasma-negative human sera with cell surfaces of 4T1 and MCF7 cell lines have been investigated. Methods: 4T1 and MCF7 cells were harvested from cell cultures and treated with either human Toxoplasma Positive or negative sera. The reaction of the sera was then detected using the flow cytometry method. Results: Toxoplasma-positive sera but not Toxoplasma-negative ones reacted very sharply with both breast cancer cell lines. Conclusions: Anti-T. gondii antibodies strongly react with breast cancer cells. These antibodies may be used for selective cancer immunotherapy in the future.

Research paper thumbnail of Fauna and the distribution of mosquitoes (Diptera: Culicidae) in Chahar Mahal and Bakhtiari Province, 2011-2012

Background and aims: Mosquitoes constitute a large family in Diptera and because of their ability... more Background and aims: Mosquitoes constitute a large family in Diptera and because of their ability in the transmission of a wide range of pathogens are of great public health and medical importance. This study was carried out to refresh our current knowledge on the fauna and the distribution of indigenous mosquitoes in Chahar Mahal and Bakhtiari Province. Methods: This descriptive, cross-sectional study was carried out during the summers of 2011 and 2012 in the all districts of Chahar Mahal and Bakhtiari Province. Larval specimens were collected by the standard dipping method and identified with the aid of valid keys. Identification data plus the geographical information of the collection sites were entered in ArcGIS 10.0 software to draw the map of distribution for each mosquito species. Results: In this investigation, 8335 larvae were collected from 92 larval habitats belonged to 18 mosquito species including Culiseta longiareolata Macquart, Cs. subochrea Edwards, Ochlerotattus cas...

Research paper thumbnail of Toxocara infection in dogs and cats in Isfahan province of Iran in 2021

Advanced Biomedical Research

Research paper thumbnail of Genotyping of Trichomonas vaginalis isolates from women in Shahrekord city (Southwestern Iran)

ABI Genetika, 2017

Trichomonas vaginalis is a causative agent of vaginitis in female and urethritis in men. It is pr... more Trichomonas vaginalis is a causative agent of vaginitis in female and urethritis in men. It is primarily transmitted by sexually route. It is known that each geographical area has its own set of Trichomonas vaginalis strain. Parasite strains in each region have its specific characterizations and different strains of the parasite are able to cause various diseases with the acuity and severity. The aim of this study was to determine the genotyping of Trichomonas vaginalis strains in the Shahrekord city (Chaharmahal Va Bakhtiari province, southwest Iran). A total of 1725 vaginal samples were taken from clinically suspected women for Trichomonas vaginalis infection and 21 specimens were diagnosed as positive by direct smear wet mount and culture repeated 1060

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