Giorgia Gatti - Academia.edu (original) (raw)
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UFMG - The Federal University of Minas Gerais
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Aim: To evaluate the pregnancy outcome and maternal complications in 166 pregnant women with chro... more Aim: To evaluate the pregnancy outcome and maternal complications in 166 pregnant women with chronic hypertension. A correlation between specific clinical features and various risk factors was made. Methods: Onehundredsixtysix pregnant women with hypertension in pharmacological treatment before pregnancy or evidence of hypertension that needed a pharmacological treatment before the 20 th week of gestation in the actual pregnancy were evaluated. Results: Fifteen patients (9%) developed preeclampsia. Thirteen deliveries (7%) were induced because of a significative rise in blood pressure and 5 women (3%) had placental abruptio. Twentyfour infants (14.6%) were LBW, 13 were VLBW (7.9%) and 35 (21%) were SGA, but only 8 (5%) showed a growth restriction in utero. A statistically significant correlation between the systolic blood pressure at the first control and IUGR (1% if PAS<140mmHg vs. 9% if PAS>140mmHg), between abnormal uterine artery Doppler velocimetry and development of superimposed PE (37% if abnormal vs. 5% if normal), IUGR (16% if abnormal vs. 1% if normal) and LBW (63% if abnormal vs. 13% if normal) was found. Other maternal factors (age, geographical origin, presence or absence of kidney diseases, smoking and an abnormal fundus oculi) were not correlated with maternal and fetal complications. Conclusions: In pregnant women with chronic hypertension, the incidence of maternal and fetal complications was found to be higher than in the general population, but lower than that reported in the literature. A systolic blood pressure higher than 140mmHg at the first control was correlated with an increased incidence IUGR.
Handbook of Systemic Autoimmune Diseases, 2009
The antiphospholipid syndrome (APS) in pregnancy is characterized by the presence of autoantibodi... more The antiphospholipid syndrome (APS) in pregnancy is characterized by the presence of autoantibodies in association with recurrent early miscarriages, fetal losses, and severe complications such as preeclampsia, placental insufficiency, or fetal growth restriction. Early-onset severe preeclampsia is sometimes complicated by the HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome, which is now grouped with the microangiopathic APS. The pathogenesis
Aim: To evaluate the pregnancy outcome and maternal complications in 166 pregnant women with chro... more Aim: To evaluate the pregnancy outcome and maternal complications in 166 pregnant women with chronic hypertension. A correlation between specific clinical features and various risk factors was made. Methods: Onehundredsixtysix pregnant women with hypertension in pharmacological treatment before pregnancy or evidence of hypertension that needed a pharmacological treatment before the 20 th week of gestation in the actual pregnancy were evaluated. Results: Fifteen patients (9%) developed preeclampsia. Thirteen deliveries (7%) were induced because of a significative rise in blood pressure and 5 women (3%) had placental abruptio. Twentyfour infants (14.6%) were LBW, 13 were VLBW (7.9%) and 35 (21%) were SGA, but only 8 (5%) showed a growth restriction in utero. A statistically significant correlation between the systolic blood pressure at the first control and IUGR (1% if PAS<140mmHg vs. 9% if PAS>140mmHg), between abnormal uterine artery Doppler velocimetry and development of superimposed PE (37% if abnormal vs. 5% if normal), IUGR (16% if abnormal vs. 1% if normal) and LBW (63% if abnormal vs. 13% if normal) was found. Other maternal factors (age, geographical origin, presence or absence of kidney diseases, smoking and an abnormal fundus oculi) were not correlated with maternal and fetal complications. Conclusions: In pregnant women with chronic hypertension, the incidence of maternal and fetal complications was found to be higher than in the general population, but lower than that reported in the literature. A systolic blood pressure higher than 140mmHg at the first control was correlated with an increased incidence IUGR.
Handbook of Systemic Autoimmune Diseases, 2009
The antiphospholipid syndrome (APS) in pregnancy is characterized by the presence of autoantibodi... more The antiphospholipid syndrome (APS) in pregnancy is characterized by the presence of autoantibodies in association with recurrent early miscarriages, fetal losses, and severe complications such as preeclampsia, placental insufficiency, or fetal growth restriction. Early-onset severe preeclampsia is sometimes complicated by the HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome, which is now grouped with the microangiopathic APS. The pathogenesis