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Papers by Gobhathai Sittironnarit

Journal of the Psychiatric Association of Thailand, Mar 29, 2018

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014

To investigate the validity and reliability of the Thai version of the confusion assessment metho... more To investigate the validity and reliability of the Thai version of the confusion assessment method (CAM). One hundred five inpatients who were consulted with the psychiatric consultation-liaison service unit, were enrolled in the present study. The validity assessment of the Thai version of the CAM was done by comparing it with the gold standard diagnosis of delirium by psychiatrists using DSM-IV-TR criteria. The reliability assessment was obtained from a sample of 35 patients assessed by two psychiatric residents. The Thai version of CAM had a sensitivity of 90% and specificity of 94.54. The positive predictive value was 93.75% and the negative predictive value was 91.23%. Likelihood ratio showed 16.5-fold risk of delirium positive through using the Thai CAM Interrater reliability in diagnosis of delirium was high (k = 0.77). The present study demonstrated that the Thai version of CAM is a valid and reliable tool for assessing and diagnosing delirium in Thailand.

Siriraj Medical Journal

Objective: To assess the psychometric properties of the Thai Mental Health Literacy Scale (TMHLS)... more Objective: To assess the psychometric properties of the Thai Mental Health Literacy Scale (TMHLS) in sixth-year medical students.Materials and Methods: By using the purposive sampling method, we enrolled 202 participants in this study. Descriptive statistics were used to analyze demographic data. The index of item-objective congruence (IOC) was used to verify content validity. Exploratory factor analysis (EFA) was performed to establish the construct validity of the TMHLS. The internal consistency was estimated by computing Cronbach’s coefficient alpha.Results: The TMHLS had good content validity (IOC=.85) and construct validity. The EFA resulted in five factors, which included 32 of the 35 items and accounted for 46.86% of the variance. The factors were the ability to recognize mental disorders; confidentiality of mental health practitioners; skills of mental health information seeking; beliefs about mental illnesses; and attitudes toward patients with mental illness. The reliabili...

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014

OBJECTIVE To investigate the validity and reliability of the Thai version of the confusion assess... more OBJECTIVE To investigate the validity and reliability of the Thai version of the confusion assessment method (CAM). MATERIAL AND METHOD One hundred five inpatients who were consulted with the psychiatric consultation-liaison service unit, were enrolled in the present study. The validity assessment of the Thai version of the CAM was done by comparing it with the gold standard diagnosis of delirium by psychiatrists using DSM-IV-TR criteria. The reliability assessment was obtained from a sample of 35 patients assessed by two psychiatric residents. RESULTS The Thai version of CAM had a sensitivity of 90% and specificity of 94.54. The positive predictive value was 93.75% and the negative predictive value was 91.23%. Likelihood ratio showed 16.5-fold risk of delirium positive through using the Thai CAM Interrater reliability in diagnosis of delirium was high (k = 0.77). CONCLUSION The present study demonstrated that the Thai version of CAM is a valid and reliable tool for assessing and di...

To determine the prevalence, risk factors and impact of non‐disclosure of HIV serostatus to sexua... more To determine the prevalence, risk factors and impact of non‐disclosure of HIV serostatus to sexual partners among HIV‐positive patients at Siriraj Hospital, Bangkok.

Objective : To study the prevalence of psychiatric disorders and personality problems in medical ... more Objective : To study the prevalence of psychiatric disorders and personality problems in medical students who were retired from Faculty of Medicine, Siriraj Hospital in academic years 1982 to 2007. Method : A retrospective descriptive study was done by analyzing the consultation record form of medical students who utilized the counseling unit of Faculty of Medicine, Siriraj Hospital between academic year 1982 and 2007 to obtain the prevalence of psychiatric disorders and personality problems and associated demographic data in retired medical students. Result : Thirty two medical students who had mental health problems were retired from the medical program. Seven students had psychiatric disorders alone, seven students had personality problems alone, and eighteen students had both psychiatric disorders and personality problems. Among 25 students with psychiatric disorders, depressive episode was diagnosed in 8 students (32% of students with mental health problems retired). Schizophre...

Objective: To study the incidence of psychiatric disorders and personality problems in Siriraj Ho... more Objective: To study the incidence of psychiatric disorders and personality problems in Siriraj Hospital medical students between academic years 1982-2007. Method: A retrospective descriptive study was done by analyzing the medical records from counseling services for all medical students who utilized counseling unit of Faculty of Medicine Siriraj Hospital between academic years 1982-2007 to obtain the rate of mental health problems and associated demographic data. Result: Mental health problems were found in 307 from 338 medical students who utilized the counseling services (90.8%). Sixty-nine percent was male. The second year was the most common year for the students to start utilizing the service. Bangkok and area around were found 65% as their accommodations. Middle level of socioeconomic status was found 54%. Self referral and staff referral were found 50.3 % and 45%, respectively. The cumulative incidence of psychiatric disorders (axis I diagnosis) and personality problems (axi...

Objectives : To find out the prevalence of psychiatric disorders, quality of life of patients and... more Objectives : To find out the prevalence of psychiatric disorders, quality of life of patients andcaregivers and their correlated factors in elderly outpatients in Siriraj Hospital.Methods : Subjects were 159 voluntary elderly (age ≥ 60 years) participants who were treatedat geriatric or psychiatric outpatient clinic in Siriraj Hospital and 36 caregivers. Evaluation toolswere SF-36 questionnaire and Mini international neuropsychiatric interview (M.I.N.I)Thai version.Descriptive analysis was used. The association between correlated factors and major depressivedisorder, and suicidality were analyzed by using Chi-square test or Fisher’s exact test and Oddratio (95%CI). The association between correlated factors and quality of life was evaluated usingMann-Whitney U-Test.Results : The most common psychiatric disorder was major depressive disorders (n=16, 10.1%).successful suicides was found in 21 patients (13.1%) even though the majority had the lowestsuicidal risk. Quality of Life in pat...

Objective: This cross-sectional descriptive research aimed to examine the quality of life of elde... more Objective: This cross-sectional descriptive research aimed to examine the quality of life of elderly people. It identified selected factors related to a quality of life and demonstrated that there were predictable qualities that affect the quality of life of elderly people in Bangkok. Method: The subjects were 388 elderly people who participated in the activities of elderly groups under the care and supervision of the Bangkok Medical Service Department. The research tools were a selected factors questionnaire and a Pictorial Thai Quality of Life (PTQL). Results: The study found that elderly people who participated in this study had high quality of life in terms of social function and self-esteem. However the physical, cognitive, affective, and economic aspects of their quality of life were mid-range. And the analytical results of this study indicated that elderly peopleus income and personal ailments were related to their quality of life. Sufficiency of income was the only factor wh...

Background: Mental health literacy reduces stigma and the risk of developing mental disorders alo... more Background: Mental health literacy reduces stigma and the risk of developing mental disorders along with increasing help-seeking behavior. The aim of this study was to translate and study both the psychometric properties of the Thai Mental Health Literacy Scale (TMHLS) and the mental health literacy in sixth-year Thai medical students of the Faculty of Medicine Siriraj Hospital, Bangkok. Methods: Two-hundred and fifty participants were enrolled using the convenience sampling method. Descriptive statistics were used to analyze demographic data and mental health experiences. Inferential statistics were applied to compare sources of mental health experiences. The content validity and reliability by internal consistency of the TMHLS was analyzed by Index of item objective congruence (IOC) obtained from the examination of three experts in mental health field and Cronbach’s Alpha, respectively. Results: The TMHLS had good content validity (IOC=.67-1.0) and good reliability (Cronbach’s alp...

Asian Journal of Psychiatry

Journal of the Psychiatric Association of Thailand, Mar 28, 2013

Journal of the Medical Association of Thailand Chotmaihet Thangphaet, 2014

To investigate the validity and reliability of the Thai version of the confusion assessment metho... more To investigate the validity and reliability of the Thai version of the confusion assessment method (CAM). One hundred five inpatients who were consulted with the psychiatric consultation-liaison service unit, were enrolled in the present study. The validity assessment of the Thai version of the CAM was done by comparing it with the gold standard diagnosis of delirium by psychiatrists using DSM-IV-TR criteria. The reliability assessment was obtained from a sample of 35 patients assessed by two psychiatric residents. The Thai version of CAM had a sensitivity of 90% and specificity of 94.54. The positive predictive value was 93.75% and the negative predictive value was 91.23%. Likelihood ratio showed 16.5-fold risk of delirium positive through using the Thai CAM Interrater reliability in diagnosis of delirium was high (k = 0.77). The present study demonstrated that the Thai version of CAM is a valid and reliable tool for assessing and diagnosing delirium in Thailand.

http://www.psychiatry.or.th/JOURNAL/55-2/07-Nantawat.pdf Objectives: To study the prevalence and ... more http://www.psychiatry.or.th/JOURNAL/55-2/07-Nantawat.pdf Objectives: To study the prevalence and associated factors of depression among patients attending the Pain Clinic at Siriraj Hospital. Method: Two hundred patients at the Pain Clinic, Siriraj Hospital were assessed by clinicians using the Thai version of the Montgomery-Asberg Depression Rating Scale (MADRS-T). The prevalence of depression and major depressive disorder was determined by using the MADRS-T at the cut-off point of > 10 for depression, and > 21 for major depressive disorder. Data analysis used percentage, mean and standard deviations, and tested for association between depression and risk factors by logistic regression. Results: There were 101 patients from the total of 200 patients with the MADRS-T score > 10, which met the criteria for depression. The prevalence of depression was 50.5%. There were 21 patients from the total of 200 patients with the MADRS-T score > 21, which met the criteria for major ...

Dementia and Geriatric Cognitive Disorders, 2011

The nature and extent of adverse cognitive effects due to the prescription of anticholinergic dru... more The nature and extent of adverse cognitive effects due to the prescription of anticholinergic drugs in older people with and without dementia is unclear. We calculated the anticholinergic load (ACL) of medications taken by participants of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing, a cohort of 211 Alzheimer's disease (AD) patients, 133 mild cognitive impairment (MCI) patients and 768 healthy controls (HC) all aged over 60 years. The association between ACL and cognitive function was examined for each diagnostic group (HC, MCI, AD). A high ACL within the HC group was associated with significantly slower response speeds for the Stroop color and incongruent trials. No other significant relationships between ACL and cognition were noted. In this large cohort, prescribed anticholinergic drugs appeared to have modest effects upon psychomotor speed and executive function, but not on other areas of cognition in healthy older adults.

Dementia and geriatric cognitive disorders, 2011

The nature and extent of adverse cognitive effects due to the prescription of anticholinergic dru... more The nature and extent of adverse cognitive effects due to the prescription of anticholinergic drugs in older people with and without dementia is unclear. We calculated the anticholinergic load (ACL) of medications taken by participants of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing, a cohort of 211 Alzheimer's disease (AD) patients, 133 mild cognitive impairment (MCI) patients and 768 healthy controls (HC) all aged over 60 years. The association between ACL and cognitive function was examined for each diagnostic group (HC, MCI, AD). A high ACL within the HC group was associated with significantly slower response speeds for the Stroop color and incongruent trials. No other significant relationships between ACL and cognition were noted. In this large cohort, prescribed anticholinergic drugs appeared to have modest effects upon psychomotor speed and executive function, but not on other areas of cognition in healthy older adults.

Journal of the Psychiatric Association of Thailand, Feb 19, 2013

Journal of the Psychiatric Association of Thailand, Feb 19, 2013

Journal of the Psychiatric Association of Thailand, Mar 29, 2018

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014

To investigate the validity and reliability of the Thai version of the confusion assessment metho... more To investigate the validity and reliability of the Thai version of the confusion assessment method (CAM). One hundred five inpatients who were consulted with the psychiatric consultation-liaison service unit, were enrolled in the present study. The validity assessment of the Thai version of the CAM was done by comparing it with the gold standard diagnosis of delirium by psychiatrists using DSM-IV-TR criteria. The reliability assessment was obtained from a sample of 35 patients assessed by two psychiatric residents. The Thai version of CAM had a sensitivity of 90% and specificity of 94.54. The positive predictive value was 93.75% and the negative predictive value was 91.23%. Likelihood ratio showed 16.5-fold risk of delirium positive through using the Thai CAM Interrater reliability in diagnosis of delirium was high (k = 0.77). The present study demonstrated that the Thai version of CAM is a valid and reliable tool for assessing and diagnosing delirium in Thailand.

Siriraj Medical Journal

Objective: To assess the psychometric properties of the Thai Mental Health Literacy Scale (TMHLS)... more Objective: To assess the psychometric properties of the Thai Mental Health Literacy Scale (TMHLS) in sixth-year medical students.Materials and Methods: By using the purposive sampling method, we enrolled 202 participants in this study. Descriptive statistics were used to analyze demographic data. The index of item-objective congruence (IOC) was used to verify content validity. Exploratory factor analysis (EFA) was performed to establish the construct validity of the TMHLS. The internal consistency was estimated by computing Cronbach’s coefficient alpha.Results: The TMHLS had good content validity (IOC=.85) and construct validity. The EFA resulted in five factors, which included 32 of the 35 items and accounted for 46.86% of the variance. The factors were the ability to recognize mental disorders; confidentiality of mental health practitioners; skills of mental health information seeking; beliefs about mental illnesses; and attitudes toward patients with mental illness. The reliabili...

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014

OBJECTIVE To investigate the validity and reliability of the Thai version of the confusion assess... more OBJECTIVE To investigate the validity and reliability of the Thai version of the confusion assessment method (CAM). MATERIAL AND METHOD One hundred five inpatients who were consulted with the psychiatric consultation-liaison service unit, were enrolled in the present study. The validity assessment of the Thai version of the CAM was done by comparing it with the gold standard diagnosis of delirium by psychiatrists using DSM-IV-TR criteria. The reliability assessment was obtained from a sample of 35 patients assessed by two psychiatric residents. RESULTS The Thai version of CAM had a sensitivity of 90% and specificity of 94.54. The positive predictive value was 93.75% and the negative predictive value was 91.23%. Likelihood ratio showed 16.5-fold risk of delirium positive through using the Thai CAM Interrater reliability in diagnosis of delirium was high (k = 0.77). CONCLUSION The present study demonstrated that the Thai version of CAM is a valid and reliable tool for assessing and di...

To determine the prevalence, risk factors and impact of non‐disclosure of HIV serostatus to sexua... more To determine the prevalence, risk factors and impact of non‐disclosure of HIV serostatus to sexual partners among HIV‐positive patients at Siriraj Hospital, Bangkok.

Objective : To study the prevalence of psychiatric disorders and personality problems in medical ... more Objective : To study the prevalence of psychiatric disorders and personality problems in medical students who were retired from Faculty of Medicine, Siriraj Hospital in academic years 1982 to 2007. Method : A retrospective descriptive study was done by analyzing the consultation record form of medical students who utilized the counseling unit of Faculty of Medicine, Siriraj Hospital between academic year 1982 and 2007 to obtain the prevalence of psychiatric disorders and personality problems and associated demographic data in retired medical students. Result : Thirty two medical students who had mental health problems were retired from the medical program. Seven students had psychiatric disorders alone, seven students had personality problems alone, and eighteen students had both psychiatric disorders and personality problems. Among 25 students with psychiatric disorders, depressive episode was diagnosed in 8 students (32% of students with mental health problems retired). Schizophre...

Objective: To study the incidence of psychiatric disorders and personality problems in Siriraj Ho... more Objective: To study the incidence of psychiatric disorders and personality problems in Siriraj Hospital medical students between academic years 1982-2007. Method: A retrospective descriptive study was done by analyzing the medical records from counseling services for all medical students who utilized counseling unit of Faculty of Medicine Siriraj Hospital between academic years 1982-2007 to obtain the rate of mental health problems and associated demographic data. Result: Mental health problems were found in 307 from 338 medical students who utilized the counseling services (90.8%). Sixty-nine percent was male. The second year was the most common year for the students to start utilizing the service. Bangkok and area around were found 65% as their accommodations. Middle level of socioeconomic status was found 54%. Self referral and staff referral were found 50.3 % and 45%, respectively. The cumulative incidence of psychiatric disorders (axis I diagnosis) and personality problems (axi...

Objectives : To find out the prevalence of psychiatric disorders, quality of life of patients and... more Objectives : To find out the prevalence of psychiatric disorders, quality of life of patients andcaregivers and their correlated factors in elderly outpatients in Siriraj Hospital.Methods : Subjects were 159 voluntary elderly (age ≥ 60 years) participants who were treatedat geriatric or psychiatric outpatient clinic in Siriraj Hospital and 36 caregivers. Evaluation toolswere SF-36 questionnaire and Mini international neuropsychiatric interview (M.I.N.I)Thai version.Descriptive analysis was used. The association between correlated factors and major depressivedisorder, and suicidality were analyzed by using Chi-square test or Fisher’s exact test and Oddratio (95%CI). The association between correlated factors and quality of life was evaluated usingMann-Whitney U-Test.Results : The most common psychiatric disorder was major depressive disorders (n=16, 10.1%).successful suicides was found in 21 patients (13.1%) even though the majority had the lowestsuicidal risk. Quality of Life in pat...

Objective: This cross-sectional descriptive research aimed to examine the quality of life of elde... more Objective: This cross-sectional descriptive research aimed to examine the quality of life of elderly people. It identified selected factors related to a quality of life and demonstrated that there were predictable qualities that affect the quality of life of elderly people in Bangkok. Method: The subjects were 388 elderly people who participated in the activities of elderly groups under the care and supervision of the Bangkok Medical Service Department. The research tools were a selected factors questionnaire and a Pictorial Thai Quality of Life (PTQL). Results: The study found that elderly people who participated in this study had high quality of life in terms of social function and self-esteem. However the physical, cognitive, affective, and economic aspects of their quality of life were mid-range. And the analytical results of this study indicated that elderly peopleus income and personal ailments were related to their quality of life. Sufficiency of income was the only factor wh...

Background: Mental health literacy reduces stigma and the risk of developing mental disorders alo... more Background: Mental health literacy reduces stigma and the risk of developing mental disorders along with increasing help-seeking behavior. The aim of this study was to translate and study both the psychometric properties of the Thai Mental Health Literacy Scale (TMHLS) and the mental health literacy in sixth-year Thai medical students of the Faculty of Medicine Siriraj Hospital, Bangkok. Methods: Two-hundred and fifty participants were enrolled using the convenience sampling method. Descriptive statistics were used to analyze demographic data and mental health experiences. Inferential statistics were applied to compare sources of mental health experiences. The content validity and reliability by internal consistency of the TMHLS was analyzed by Index of item objective congruence (IOC) obtained from the examination of three experts in mental health field and Cronbach’s Alpha, respectively. Results: The TMHLS had good content validity (IOC=.67-1.0) and good reliability (Cronbach’s alp...

Asian Journal of Psychiatry

Journal of the Psychiatric Association of Thailand, Mar 28, 2013

Journal of the Medical Association of Thailand Chotmaihet Thangphaet, 2014

To investigate the validity and reliability of the Thai version of the confusion assessment metho... more To investigate the validity and reliability of the Thai version of the confusion assessment method (CAM). One hundred five inpatients who were consulted with the psychiatric consultation-liaison service unit, were enrolled in the present study. The validity assessment of the Thai version of the CAM was done by comparing it with the gold standard diagnosis of delirium by psychiatrists using DSM-IV-TR criteria. The reliability assessment was obtained from a sample of 35 patients assessed by two psychiatric residents. The Thai version of CAM had a sensitivity of 90% and specificity of 94.54. The positive predictive value was 93.75% and the negative predictive value was 91.23%. Likelihood ratio showed 16.5-fold risk of delirium positive through using the Thai CAM Interrater reliability in diagnosis of delirium was high (k = 0.77). The present study demonstrated that the Thai version of CAM is a valid and reliable tool for assessing and diagnosing delirium in Thailand.

http://www.psychiatry.or.th/JOURNAL/55-2/07-Nantawat.pdf Objectives: To study the prevalence and ... more http://www.psychiatry.or.th/JOURNAL/55-2/07-Nantawat.pdf Objectives: To study the prevalence and associated factors of depression among patients attending the Pain Clinic at Siriraj Hospital. Method: Two hundred patients at the Pain Clinic, Siriraj Hospital were assessed by clinicians using the Thai version of the Montgomery-Asberg Depression Rating Scale (MADRS-T). The prevalence of depression and major depressive disorder was determined by using the MADRS-T at the cut-off point of > 10 for depression, and > 21 for major depressive disorder. Data analysis used percentage, mean and standard deviations, and tested for association between depression and risk factors by logistic regression. Results: There were 101 patients from the total of 200 patients with the MADRS-T score > 10, which met the criteria for depression. The prevalence of depression was 50.5%. There were 21 patients from the total of 200 patients with the MADRS-T score > 21, which met the criteria for major ...

Dementia and Geriatric Cognitive Disorders, 2011

The nature and extent of adverse cognitive effects due to the prescription of anticholinergic dru... more The nature and extent of adverse cognitive effects due to the prescription of anticholinergic drugs in older people with and without dementia is unclear. We calculated the anticholinergic load (ACL) of medications taken by participants of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing, a cohort of 211 Alzheimer's disease (AD) patients, 133 mild cognitive impairment (MCI) patients and 768 healthy controls (HC) all aged over 60 years. The association between ACL and cognitive function was examined for each diagnostic group (HC, MCI, AD). A high ACL within the HC group was associated with significantly slower response speeds for the Stroop color and incongruent trials. No other significant relationships between ACL and cognition were noted. In this large cohort, prescribed anticholinergic drugs appeared to have modest effects upon psychomotor speed and executive function, but not on other areas of cognition in healthy older adults.

Dementia and geriatric cognitive disorders, 2011

The nature and extent of adverse cognitive effects due to the prescription of anticholinergic dru... more The nature and extent of adverse cognitive effects due to the prescription of anticholinergic drugs in older people with and without dementia is unclear. We calculated the anticholinergic load (ACL) of medications taken by participants of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing, a cohort of 211 Alzheimer's disease (AD) patients, 133 mild cognitive impairment (MCI) patients and 768 healthy controls (HC) all aged over 60 years. The association between ACL and cognitive function was examined for each diagnostic group (HC, MCI, AD). A high ACL within the HC group was associated with significantly slower response speeds for the Stroop color and incongruent trials. No other significant relationships between ACL and cognition were noted. In this large cohort, prescribed anticholinergic drugs appeared to have modest effects upon psychomotor speed and executive function, but not on other areas of cognition in healthy older adults.

Journal of the Psychiatric Association of Thailand, Feb 19, 2013

Journal of the Psychiatric Association of Thailand, Feb 19, 2013