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Papers by Hamidreza Jamilian

Turkish Archives of Pediatrics

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, Apr 1, 2021

Background and Aim The development of any society depends on the educational system of that socie... more Background and Aim The development of any society depends on the educational system of that society. The educational system can be efficient and successful when considering the academic performance of learners in different courses. This study aimed to investigate the effects of mental self-care education on students' mental health and academic motivation. Methods & Materials This was a quasi-experimental study with unequal control and experimental groups. The statistical population of this study was students referring to school counseling centers; 40 of them (n=20/ group) were selected by random sampling method. The Depression, Anxiety, and Stress Scale-21 Items (DASS-21), and Academic Performance Rating Scale were used to collect the necessary data. Psychological self-care training was presented to the experimental group in ten 2-hour sessions. Then, a posttest was conducted on the study groups. Data analysis was performed using Multivariate Analysis of Covariance (MANCOVA). Ethical Considerations This article was approved by the Ethics Committee of the Islamic Azad University, Khomeini Branch (Code: IR.IAU.ARAK.REC.1399.001). Results The obtained findings indicated that mental self-care education was effective on students' mental health (P<0.05). Furthermore, psychological self-care education was ineffective on students' academic motivation. Conclusion Mental self-care education was used to improve mental health; however, this training did not affect academic motivation in the examined subjects.

Open Access Macedonian Journal of Medical Sciences, 2020

AIM: The aim of our study was to determine the effect of adjunctive use of dexmedetomidine and me... more AIM: The aim of our study was to determine the effect of adjunctive use of dexmedetomidine and metoral with thiopental on hemodynamic status, agitation, patient satisfaction, and duration of seizure in patients with mood disorders in electroconvulsive therapy (ECT). METHODS: This study is a randomized, double-blind, clinical trial. Sixty patients (18–60 years) according to DSM5 criteria had mood disorder and were candidates for ECT. Patients were randomly divided into two groups of 30 each. One group received 5.0 μg/kg dexmedetomidine 10 min before induction of thiopental, and the other group received 5.2 mg intravenous metoprolol immediately before ECT. Patients’ satisfaction, duration of seizure, and arterial oxygen saturation were evaluated. RESULTS: The mean age of both groups was approximately 37 years with the majority of men. No significant difference was found between the two groups in terms of age and sex, blood pressure (BP), heart rate (HR), duration of seizure, and arter...

Journal of Arak University Medical Sciences, 2021

Background and Aim: Major Depressive Disorder (MDD) is the most common mental health condition, w... more Background and Aim: Major Depressive Disorder (MDD) is the most common mental health condition, with a severe decline in performance, disability, and a 15% risk of suicide. Allopurinol increases the level of tryptophan in the body by inhibiting xanthine oxidase, and by elevating the level of tryptophan, i.e., a precursor to serotonin. Accordingly, it can improve the symptoms of depression. This study aimed to investigate the impact of allopurinol on MDD. Methods & Materials: In this double-blind clinical trial, 70 patients with MDD, diagnosed based on the Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition-Third Edition (DSM IV-TR) were randomly (paired & individual patient records) divided into two equal groups. Both research groups received 40 mg of citalopram daily for 6 weeks. In addition to citalopram, the intervention group received 300 mg allopurinol daily and the control group received a placebo. At the end of the third and sixth weeks, the examined patient...

Gene Reports, 2021

Abstract Hepatocellular carcinoma (HCC) is one of the most common malignancies and a major cause ... more Abstract Hepatocellular carcinoma (HCC) is one of the most common malignancies and a major cause of cancer-related deaths worldwide due to the high mortality rate and unfavorable satisfaction treatment options available. However, a detailed understanding of the molecular mechanisms underlying liver cancer has not yet been established. piRNAs are RNA molecules with the estimated size of 26–31 nt binding to Piwi proteins. PIWI-interacting RNAs (piRNAs) are small non-coding RNAs (sncRNAs) that are composed of 24-32 nucleotides. These RNAs are responsible for epigenetic regulation and post-transcriptional regulation of gene expression. PIWI-piRNA pathway is the best characteristic of germ cells that have recently been identified in somatic tissues, including stem cells and cancer cells. Several studies have shown that this pathway plays an important role in individual cellular processes. Evidence is shown that abnormal piRNA expression is an important factor involved in cancer cell proliferation, apoptosis, invasion and migration in vitro and in vivo. Altered expression of piRNA in cancer is associated with clinical outcomes, highlighting the important role that they may serve as new diagnostic and prognostic biomarkers and as therapeutic targets for cancer treatment. Therefore, we have focused on PIWI proteins and piRNA functions and their effects on the progression of liver cancer.

Allergic rhinitis is a common disease presenting in 20% of the population. Major symptoms are inc... more Allergic rhinitis is a common disease presenting in 20% of the population. Major symptoms are including sneezing, rhinorrhea, nasal congestion, and nasal pruritus. It is seemed that tricyclic antidepressants blocking histamine receptors might be applied as an effective treatment in allergic rhinitis. In the current clinical trial, a total of 84 subjects with allergic rhinitis were enrolled and randomly assigned to 2 groups. Both groups were administered cetirizine and doxepin for 2 weeks. The subjects were evaluated in terms of sneezing, rhinorrhea, nasal congestion, and nasal pruritus after 2 weeks of taking the aforementioned medications. There was no difference in the clinical score of the patients after 2 weeks (p = 0.261). Sneezing was the only symptom that was affected by the type of remedy, it was significantly different between the groups (p = 0.005). The findings of the present study indicated that there is no substantial difference in taking cetirizine and doxepin in treat...

Arak Medical University Journal, 2016

Background: Adoption has a significant role for strengthening families without children and also ... more Background: Adoption has a significant role for strengthening families without children and also resolution of psychological confilicts of unsupervised children. The goal of this study is to assess the psychological status of adoption applicant couples. Materials and Methods: This is a descriptive- analytic study that is done with cooperation of welfare organization and Arak University of Medical Sciences in 2014. All adoption applicant couples referred to welfare organization for 1 year participated in the study. Data were gathered by using demographic questionnaire and MMPI-II. Data were showed by descriptive statistic and were analyzed by using mean, average and covariance analysis indices. Results: Mean and standard deviation of all clinical scales and reliability of MMPI-II in all samples and also different subgroups of statistical population were under 65. All applicants had good mental health and psychologically were eligible for adoption. A group of applicants have pretended...

Arak Medical University Journal, 2015

Compare of the effect of doxepin and citerizine in treatment of allergic rhinitis Zamani Barsari ... more Compare of the effect of doxepin and citerizine in treatment of allergic rhinitis Zamani Barsari F 1 , Soheili H 2 , Jamilian HR3 , Saleh Jafari N 1* , Rafiei M 4 , Tamizi A 5 1- Department of ENT, Arak University of Medical Sciences, Arak, Iran 2- Department of Pediatrics, Arak University of medical sciences, Arak, Iran 3- Department of Psychiatrics, Arak University of medical sciences, Arak, Iran 4- Department of Statistics, Arak University of medical sciences, Arak, Iran 5- Arak University of medical sciences, Arak, Iran Abstract Background: Allergic rhinitis is a common disease which is present in 20% of general population. Major symptoms include sneezing, rhinorrhea, nasal congestion, and nasal pruritus. It seems that tricyclic antidepressants blocking histamine receptors may be used as an effective treatment in allergic rhinitis. Materials and Methods: In this clinical trial study, 84 patients with allergic rhinitis entered the study and randomly divided into two groups. Patie...

Journal of patient safety and quality improvement, 2017

Introduction: Along with some authors through literature indicating the influence of infertility ... more Introduction: Along with some authors through literature indicating the influence of infertility on the quality of life, this study aimed at comparing the impact of infertility on the quality of life and social support among fertile and infertile women. Materials and Methods: In this case-control study, 50 hospitalized and outpatient infertile women and 50 fertile women aged 20-40 referred to gynecology, obstetrics and infertility centers of Arak University of Medical Sciences from March 2013 to August 2013. The patients were requested to complete the Persian version of the WHOQOL-BREF (world health organization quality of life) and social support questionnaires. The demographic data and data extracted from questionnaires were collected and analyzed. Results:100 women (50 infertile and 50 fertile) with the average age of 33.70±6.53 were recruited. All patients were literate and had a high school diploma. To compare two groups regarding physical health, mental health, social relation...

Arak Medical University Journal, 2016

Background: The definite treatment of indicated Hypertrophy of the tonsils is Tonsillectomy. The ... more Background: The definite treatment of indicated Hypertrophy of the tonsils is Tonsillectomy. The aim of this study was to compare the efficacy and necessity of diclofenac suppository and simultaneous prescription of acetaminophen alone in controlling and reducing pain and improving swallowing and satisfaction after surgery for tonsillectomy in children. Materials and Methods: In this clinical trial, 180 children 7 to 14 years Tvnsykltvmy surgery were enrolled. Patients in an improbable way, easy and were divided into three groups of 60. Immediately after the surgery acetaminophen, diclofenac, or a combination of both was used. The cases of pain in the early hours, seventh, thirteenth and nineteenth after surgery were compared. Results: There was a significant difference between the average pains of all groups in all hours (p<0.05). There was a significant difference between the groups from the point of view of side effects such as Nausea, Vomiting and Pyrexia (p<0.05), But the...

Iranian Journal of Psychiatry and Clinical Psychology, 2021

Objectives: Given the outbreak of COVID-19 pandemic and its adverse effects on social psychologic... more Objectives: Given the outbreak of COVID-19 pandemic and its adverse effects on social psychological health, especially nurses, psychological empowerment of nurses can increase their psychological security and improve their clinical performance during critical situations. This study aims to investigate the relationship between nurses’ psychology capital and their clinical performance, with a focus on the intermediary role of psychological security while facing COVID-19 patients. Methods: This was a descriptive-analytical study. A total of 100 nurses (from 114 nurses) employed in the COVID-19 section of Amir-Al-Momenin Hospital in Arak City, Iran, were selected via the convenience sampling method. The data collection was done using three questionnaires: Luthan’s psychological capital questionnaire, perceived psychological questionnaire, and evidence-based questionnaire. To analyze the data and confirm the fitness of the tools, we used the confirmatory factor analysis with partial leas...

European Journal of Translational Myology, 2020

Electroconvulsive therapy (ECT) is one of the appropriate treatments for many neuropsychiatric pa... more Electroconvulsive therapy (ECT) is one of the appropriate treatments for many neuropsychiatric patients, especially those with mood disorders. Short-term complications of ECT include agitation and postictal. In this study, we compared the addition of dexmedetomidine or remifentanil to thiopental as the main anaesthetic used in ECT. In this double-blind randomised clinical trial, 90 patients with mood disorders (candidates for ECT) were divided into two groups based on their therapy: dexmedetomidine or remifentanil. In the first group (DG), patients were slowly injected intravenously with 0.5 μg/kg dexmedetomidine before induction of anesthesia. In the second group (GR), 100 μg of remifentanil was slowly injected intravenously.In addition, we collected demographic information such as respiratory rate, heart pulse rate, seizure time, mean of arterial blood pressure, recovery duration and the oxygen arterial saturation recorded after recovery. Data obtained were analysed by use of stat...

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2019

Background: In the current meta-analysis of randomized controlled trials (RCTs), the effects of v... more Background: In the current meta-analysis of randomized controlled trials (RCTs), the effects of vitamin D supplementation on mental health, and biomarkers of inflammation and oxidative stress in patients with psychiatric disorders are assessed. Methods: The following databases were search up to March 2019: MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials. The quality of the relevant extracted data was assessed according to the Cochrane risk of bias tool. Data were pooled by the use of the inverse variance method and expressed as mean difference with 95% Confidence Intervals (95% CI). Results: Eleven effect sizes from nine studies were included in the final analyses. A pooled analysis of 9 effect sizes showed a significant reduction in Beck Depression Inventory (BDI) score following supplementation with vitamin D [weighted mean difference (WMD):-3.91; 95% CI:-5.15-2.66), I 2 = 85.9%]. Combining data from two available studies on the effects of vitamin D supplementation on Pittsburgh Sleep Quality Index (PSQI) also revealed a significant reduction in this score following the intervention (WMD:-1.78; 95% CI:-2.28,-1.28). In addition, there were significant increase in glutathione (GSH) through 3 studies (WMD: 180.70; 95% CI: 6.76, 354.64), and in total antioxidant capacity (TAC) through 3 studies (WMD: 90.09; 95% CI: 56.36, 123.82) after vitamin D supplementation. Combining data from five studies, we found a significant reduction in C-reactive protein (CRP) concentrations after vitamin D supplementation (WMD:-1.74; 95% CI:-2.82,-0.66). Conclusions: Overall, the current meta-analysis demonstrated that taking vitamin D supplements among patients with psychiatric disorders had beneficial effects on BDI, PSQI, GSH, TAC and CRP levels, but did not affect other biomarkers of inflammation and oxidative stress.

Journal of Psychosomatic Obstetrics & Gynecology, 2017

Abstract Introduction: Data on comparison of myo-inositol and metformin on mental health paramete... more Abstract Introduction: Data on comparison of myo-inositol and metformin on mental health parameters and biomarkers of oxidative stress in subjects with polycystic ovary syndrome (PCOS) are scarce. This purpose of this study was to compare of myo-inositol and metformin on mental health parameters and biomarkers of oxidative stress in subjects with PCOS. Methods: This randomized controlled trial was conducted among 60 subjects diagnosed with PCOS according to the Rotterdam criteria. Subjects were randomly assigned into two groups to intake either myo-inositol (n = 30) or metformin (n = 30) for 12 weeks. Parameters of mental health were recorded at baseline and after the 12-week intervention. Fasting blood samples were obtained at baseline and the end of the study to determine biomarkers of biomarkers of oxidative stress. Results: After the 12-week intervention, changes in beck depression inventory total score (−1.0 ± 1.7 vs. −0.3 ± 0.7, p = 0.03), general health questionnaire scores (−1.7 ± 2.9 vs. −0.5 ± 1.2, p = 0.02), depression anxiety and stress scale scores (−3.9 ± 6.4 vs. −0.9 ± 1.9, p = 0.01) and plasma total antioxidant capacity (TAC) concentrations (+106.1 ± 69.6 vs. +2.1 ± 132.4 mmol/L, p < 0.001) in the myo-inositol group were significantly different from the changes in these indicators in the metformin group. Myo-inositol supplementation for 12 weeks among patients with PCOS did not affect plasma glutathione and malondialdehyde levels. Conclusions: Overall, our data supported that myo-inositol supplementation for 12 weeks among patients with PCOS had favorable effects on parameters of mental health and plasma TAC levels.

Clinical Nutrition, 2018

Background and aims: The objective of this investigation was to assess the effects of probiotic a... more Background and aims: The objective of this investigation was to assess the effects of probiotic and selenium co-supplementation on indicators of mental health and metabolic profiles in diabetic people with coronary heart disease (CHD). Methods: This randomized, double-blind, placebo-controlled trial was conducted among 54 diabetic people with CHD. Patients were randomly allocated into two groups to receive either 200 mg/day selenium plus 8 Â 10 9 CFU/day probiotic (n ¼ 27) or placebo (n ¼ 27) for 12 weeks.

Journal of affective disorders, Mar 15, 2018

The aim of this study was to evaluate the effects of omega-3 and vitamin E co-supplementation on ... more The aim of this study was to evaluate the effects of omega-3 and vitamin E co-supplementation on parameters of mental health and gene expression related to insulin and inflammation in subjects with polycystic ovary syndrome (PCOS). Forty PCOS women were allocated into two groups and treated with 1000mg omega-3 fatty acids plus 400 IU vitamin E supplements (n = 20) or placebo (n = 20) per day for 12 weeks. Parameters of mental health were recorded at baseline and after the 12-week intervention. Gene expression related to insulin and inflammation were measured in blood samples of PCOS women. After the 12-week intervention, compared with the placebo, omega-3 and vitamin E co-supplementation led to significant improvements in beck depression inventory total score (- 2.2 ± 2.0 vs. - 0.2 ± 1.3, P = 0.001), general health questionnaire scores (- 5.5 ± 4.6 vs. - 1.0 ± 2.3, P < 0.001) and depression anxiety and stress scale scores (- 7.2 ± 5.2 vs. - 1.3 ± 1.3, P < 0.001). Compared with...

Gynecological Endocrinology, 2017

Introduction: Limited data are available assessing the effects of oral carnitine supplementation ... more Introduction: Limited data are available assessing the effects of oral carnitine supplementation on mental health parameters and biomarkers of oxidative stress of women with polycystic ovary syndrome (PCOS).This study was designed to determine the effects of oral carnitine supplementation on mental health parameters and biomarkers of oxidative stress in women with PCOS. Methods: In the current randomized, double-blind, placebo-controlled trial, 60 patients diagnosed with PCOS were randomized to take either 250 mg carnitine supplements (n ¼ 30) or placebo (n ¼ 30) for 12 weeks. Results: After 12 weeks' intervention, compared with the placebo, carnitine supplementation resulted in a significant improvement in Beck Depression Inventory total score (À2.7 ± 2.3 versus À0.2 ± 0.7, p50.001), General Health Questionnaire scores (À6.9 ± 4.9 versus À0.9 ± 1.5, p50.001) and Depression Anxiety and Stress Scale scores (À8.7 ± 5.9 versus À1.2 ± 2.9, p ¼ 0.001). In addition, changes in plasma total antioxidant capacity (TAC) (+84.1 ± 151.8 versus +4.6 ± 64.5 mmol/L, p ¼ 0.01), malondialdehyde (MDA) (À0.4 ± 1.0 versus +0.5 ± 1.5 mmol/L, p ¼ 0.01) and MDA/TAC ratio (À0.0005 ± 0.0010 versus +0.0006 ± 0.0019, p ¼ 0.003) in the supplemented group were significantly different from the changes in these indicators in the placebo group. Conclusions: Overall, our study demonstrated that carnitine supplementation for 12 weeks among patients with PCOS had favorable effects on parameters of mental health and biomarkers of oxidative stress.

European Psychiatry, 2011

IntroductionInfertility affects life of couples and family function. Infertility can cause mental... more IntroductionInfertility affects life of couples and family function. Infertility can cause mental disturbances in some studies.AimsThe goal of this study was the comparison of mental health in fertile and infertile women.MethodsA case-control study was done in Arak-Iran, Taleghani hospital which is a center of Gynecology, in 2010. 60 infertile women as case group and 60 fertile women as control group participated in the study, randomly. Both groups were assessed by GHQ questionnaire and data were analyzed by T-Test and logistic regression.ResultsThe severity of mental disturbances were much more in infertile women (P < 0.001). Social dysfunction (P < 0.001) and somatic complaints (P < 0.001) were also higher in infertile women. The probability of mental disturbances was much higher in infertile women (P < 0.001 and OR = 5.57).ConclusionMental health of infertile women is very critical and disturbed. The findings of our study necessitate the multidimensional interventions...

APOS Trends in Orthodontics, 2015

Objective Improvement in appearance is an important motivation for orthodontic treatment; neverth... more Objective Improvement in appearance is an important motivation for orthodontic treatment; nevertheless, not all patients with malocclusion seek treatment; therefore, the aim of this study was to compare the psychological state of patients with moderate to severe malocclusion who seek orthodontic treatment with patients who suffer from similar malocclusion but do not seek treatment. Materials and Methods Minnesota multiphasic personality inventory-2 questionnaire which assesses psychological states of people were given to 100 subject with moderate to severe malocclusion who were undergoing orthodontic treatment and 100 subjects with similar malocclusion who did not request orthodontic treatment. All subjects had similar demographic variables. Clinical scales measured by the test included: Hypochondriasis, depression, hysteria, psychopathic deviate, paranoia, psychasthenia, schizophrenia, and hypomania. The questionnaire consisted of 71 questions, and the subjects had to mark “True” o...

Turkish Archives of Pediatrics

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, Apr 1, 2021

Background and Aim The development of any society depends on the educational system of that socie... more Background and Aim The development of any society depends on the educational system of that society. The educational system can be efficient and successful when considering the academic performance of learners in different courses. This study aimed to investigate the effects of mental self-care education on students' mental health and academic motivation. Methods & Materials This was a quasi-experimental study with unequal control and experimental groups. The statistical population of this study was students referring to school counseling centers; 40 of them (n=20/ group) were selected by random sampling method. The Depression, Anxiety, and Stress Scale-21 Items (DASS-21), and Academic Performance Rating Scale were used to collect the necessary data. Psychological self-care training was presented to the experimental group in ten 2-hour sessions. Then, a posttest was conducted on the study groups. Data analysis was performed using Multivariate Analysis of Covariance (MANCOVA). Ethical Considerations This article was approved by the Ethics Committee of the Islamic Azad University, Khomeini Branch (Code: IR.IAU.ARAK.REC.1399.001). Results The obtained findings indicated that mental self-care education was effective on students' mental health (P<0.05). Furthermore, psychological self-care education was ineffective on students' academic motivation. Conclusion Mental self-care education was used to improve mental health; however, this training did not affect academic motivation in the examined subjects.

Open Access Macedonian Journal of Medical Sciences, 2020

AIM: The aim of our study was to determine the effect of adjunctive use of dexmedetomidine and me... more AIM: The aim of our study was to determine the effect of adjunctive use of dexmedetomidine and metoral with thiopental on hemodynamic status, agitation, patient satisfaction, and duration of seizure in patients with mood disorders in electroconvulsive therapy (ECT). METHODS: This study is a randomized, double-blind, clinical trial. Sixty patients (18–60 years) according to DSM5 criteria had mood disorder and were candidates for ECT. Patients were randomly divided into two groups of 30 each. One group received 5.0 μg/kg dexmedetomidine 10 min before induction of thiopental, and the other group received 5.2 mg intravenous metoprolol immediately before ECT. Patients’ satisfaction, duration of seizure, and arterial oxygen saturation were evaluated. RESULTS: The mean age of both groups was approximately 37 years with the majority of men. No significant difference was found between the two groups in terms of age and sex, blood pressure (BP), heart rate (HR), duration of seizure, and arter...

Journal of Arak University Medical Sciences, 2021

Background and Aim: Major Depressive Disorder (MDD) is the most common mental health condition, w... more Background and Aim: Major Depressive Disorder (MDD) is the most common mental health condition, with a severe decline in performance, disability, and a 15% risk of suicide. Allopurinol increases the level of tryptophan in the body by inhibiting xanthine oxidase, and by elevating the level of tryptophan, i.e., a precursor to serotonin. Accordingly, it can improve the symptoms of depression. This study aimed to investigate the impact of allopurinol on MDD. Methods & Materials: In this double-blind clinical trial, 70 patients with MDD, diagnosed based on the Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition-Third Edition (DSM IV-TR) were randomly (paired & individual patient records) divided into two equal groups. Both research groups received 40 mg of citalopram daily for 6 weeks. In addition to citalopram, the intervention group received 300 mg allopurinol daily and the control group received a placebo. At the end of the third and sixth weeks, the examined patient...

Gene Reports, 2021

Abstract Hepatocellular carcinoma (HCC) is one of the most common malignancies and a major cause ... more Abstract Hepatocellular carcinoma (HCC) is one of the most common malignancies and a major cause of cancer-related deaths worldwide due to the high mortality rate and unfavorable satisfaction treatment options available. However, a detailed understanding of the molecular mechanisms underlying liver cancer has not yet been established. piRNAs are RNA molecules with the estimated size of 26–31 nt binding to Piwi proteins. PIWI-interacting RNAs (piRNAs) are small non-coding RNAs (sncRNAs) that are composed of 24-32 nucleotides. These RNAs are responsible for epigenetic regulation and post-transcriptional regulation of gene expression. PIWI-piRNA pathway is the best characteristic of germ cells that have recently been identified in somatic tissues, including stem cells and cancer cells. Several studies have shown that this pathway plays an important role in individual cellular processes. Evidence is shown that abnormal piRNA expression is an important factor involved in cancer cell proliferation, apoptosis, invasion and migration in vitro and in vivo. Altered expression of piRNA in cancer is associated with clinical outcomes, highlighting the important role that they may serve as new diagnostic and prognostic biomarkers and as therapeutic targets for cancer treatment. Therefore, we have focused on PIWI proteins and piRNA functions and their effects on the progression of liver cancer.

Allergic rhinitis is a common disease presenting in 20% of the population. Major symptoms are inc... more Allergic rhinitis is a common disease presenting in 20% of the population. Major symptoms are including sneezing, rhinorrhea, nasal congestion, and nasal pruritus. It is seemed that tricyclic antidepressants blocking histamine receptors might be applied as an effective treatment in allergic rhinitis. In the current clinical trial, a total of 84 subjects with allergic rhinitis were enrolled and randomly assigned to 2 groups. Both groups were administered cetirizine and doxepin for 2 weeks. The subjects were evaluated in terms of sneezing, rhinorrhea, nasal congestion, and nasal pruritus after 2 weeks of taking the aforementioned medications. There was no difference in the clinical score of the patients after 2 weeks (p = 0.261). Sneezing was the only symptom that was affected by the type of remedy, it was significantly different between the groups (p = 0.005). The findings of the present study indicated that there is no substantial difference in taking cetirizine and doxepin in treat...

Arak Medical University Journal, 2016

Background: Adoption has a significant role for strengthening families without children and also ... more Background: Adoption has a significant role for strengthening families without children and also resolution of psychological confilicts of unsupervised children. The goal of this study is to assess the psychological status of adoption applicant couples. Materials and Methods: This is a descriptive- analytic study that is done with cooperation of welfare organization and Arak University of Medical Sciences in 2014. All adoption applicant couples referred to welfare organization for 1 year participated in the study. Data were gathered by using demographic questionnaire and MMPI-II. Data were showed by descriptive statistic and were analyzed by using mean, average and covariance analysis indices. Results: Mean and standard deviation of all clinical scales and reliability of MMPI-II in all samples and also different subgroups of statistical population were under 65. All applicants had good mental health and psychologically were eligible for adoption. A group of applicants have pretended...

Arak Medical University Journal, 2015

Compare of the effect of doxepin and citerizine in treatment of allergic rhinitis Zamani Barsari ... more Compare of the effect of doxepin and citerizine in treatment of allergic rhinitis Zamani Barsari F 1 , Soheili H 2 , Jamilian HR3 , Saleh Jafari N 1* , Rafiei M 4 , Tamizi A 5 1- Department of ENT, Arak University of Medical Sciences, Arak, Iran 2- Department of Pediatrics, Arak University of medical sciences, Arak, Iran 3- Department of Psychiatrics, Arak University of medical sciences, Arak, Iran 4- Department of Statistics, Arak University of medical sciences, Arak, Iran 5- Arak University of medical sciences, Arak, Iran Abstract Background: Allergic rhinitis is a common disease which is present in 20% of general population. Major symptoms include sneezing, rhinorrhea, nasal congestion, and nasal pruritus. It seems that tricyclic antidepressants blocking histamine receptors may be used as an effective treatment in allergic rhinitis. Materials and Methods: In this clinical trial study, 84 patients with allergic rhinitis entered the study and randomly divided into two groups. Patie...

Journal of patient safety and quality improvement, 2017

Introduction: Along with some authors through literature indicating the influence of infertility ... more Introduction: Along with some authors through literature indicating the influence of infertility on the quality of life, this study aimed at comparing the impact of infertility on the quality of life and social support among fertile and infertile women. Materials and Methods: In this case-control study, 50 hospitalized and outpatient infertile women and 50 fertile women aged 20-40 referred to gynecology, obstetrics and infertility centers of Arak University of Medical Sciences from March 2013 to August 2013. The patients were requested to complete the Persian version of the WHOQOL-BREF (world health organization quality of life) and social support questionnaires. The demographic data and data extracted from questionnaires were collected and analyzed. Results:100 women (50 infertile and 50 fertile) with the average age of 33.70±6.53 were recruited. All patients were literate and had a high school diploma. To compare two groups regarding physical health, mental health, social relation...

Arak Medical University Journal, 2016

Background: The definite treatment of indicated Hypertrophy of the tonsils is Tonsillectomy. The ... more Background: The definite treatment of indicated Hypertrophy of the tonsils is Tonsillectomy. The aim of this study was to compare the efficacy and necessity of diclofenac suppository and simultaneous prescription of acetaminophen alone in controlling and reducing pain and improving swallowing and satisfaction after surgery for tonsillectomy in children. Materials and Methods: In this clinical trial, 180 children 7 to 14 years Tvnsykltvmy surgery were enrolled. Patients in an improbable way, easy and were divided into three groups of 60. Immediately after the surgery acetaminophen, diclofenac, or a combination of both was used. The cases of pain in the early hours, seventh, thirteenth and nineteenth after surgery were compared. Results: There was a significant difference between the average pains of all groups in all hours (p<0.05). There was a significant difference between the groups from the point of view of side effects such as Nausea, Vomiting and Pyrexia (p<0.05), But the...

Iranian Journal of Psychiatry and Clinical Psychology, 2021

Objectives: Given the outbreak of COVID-19 pandemic and its adverse effects on social psychologic... more Objectives: Given the outbreak of COVID-19 pandemic and its adverse effects on social psychological health, especially nurses, psychological empowerment of nurses can increase their psychological security and improve their clinical performance during critical situations. This study aims to investigate the relationship between nurses’ psychology capital and their clinical performance, with a focus on the intermediary role of psychological security while facing COVID-19 patients. Methods: This was a descriptive-analytical study. A total of 100 nurses (from 114 nurses) employed in the COVID-19 section of Amir-Al-Momenin Hospital in Arak City, Iran, were selected via the convenience sampling method. The data collection was done using three questionnaires: Luthan’s psychological capital questionnaire, perceived psychological questionnaire, and evidence-based questionnaire. To analyze the data and confirm the fitness of the tools, we used the confirmatory factor analysis with partial leas...

European Journal of Translational Myology, 2020

Electroconvulsive therapy (ECT) is one of the appropriate treatments for many neuropsychiatric pa... more Electroconvulsive therapy (ECT) is one of the appropriate treatments for many neuropsychiatric patients, especially those with mood disorders. Short-term complications of ECT include agitation and postictal. In this study, we compared the addition of dexmedetomidine or remifentanil to thiopental as the main anaesthetic used in ECT. In this double-blind randomised clinical trial, 90 patients with mood disorders (candidates for ECT) were divided into two groups based on their therapy: dexmedetomidine or remifentanil. In the first group (DG), patients were slowly injected intravenously with 0.5 μg/kg dexmedetomidine before induction of anesthesia. In the second group (GR), 100 μg of remifentanil was slowly injected intravenously.In addition, we collected demographic information such as respiratory rate, heart pulse rate, seizure time, mean of arterial blood pressure, recovery duration and the oxygen arterial saturation recorded after recovery. Data obtained were analysed by use of stat...

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2019

Background: In the current meta-analysis of randomized controlled trials (RCTs), the effects of v... more Background: In the current meta-analysis of randomized controlled trials (RCTs), the effects of vitamin D supplementation on mental health, and biomarkers of inflammation and oxidative stress in patients with psychiatric disorders are assessed. Methods: The following databases were search up to March 2019: MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials. The quality of the relevant extracted data was assessed according to the Cochrane risk of bias tool. Data were pooled by the use of the inverse variance method and expressed as mean difference with 95% Confidence Intervals (95% CI). Results: Eleven effect sizes from nine studies were included in the final analyses. A pooled analysis of 9 effect sizes showed a significant reduction in Beck Depression Inventory (BDI) score following supplementation with vitamin D [weighted mean difference (WMD):-3.91; 95% CI:-5.15-2.66), I 2 = 85.9%]. Combining data from two available studies on the effects of vitamin D supplementation on Pittsburgh Sleep Quality Index (PSQI) also revealed a significant reduction in this score following the intervention (WMD:-1.78; 95% CI:-2.28,-1.28). In addition, there were significant increase in glutathione (GSH) through 3 studies (WMD: 180.70; 95% CI: 6.76, 354.64), and in total antioxidant capacity (TAC) through 3 studies (WMD: 90.09; 95% CI: 56.36, 123.82) after vitamin D supplementation. Combining data from five studies, we found a significant reduction in C-reactive protein (CRP) concentrations after vitamin D supplementation (WMD:-1.74; 95% CI:-2.82,-0.66). Conclusions: Overall, the current meta-analysis demonstrated that taking vitamin D supplements among patients with psychiatric disorders had beneficial effects on BDI, PSQI, GSH, TAC and CRP levels, but did not affect other biomarkers of inflammation and oxidative stress.

Journal of Psychosomatic Obstetrics & Gynecology, 2017

Abstract Introduction: Data on comparison of myo-inositol and metformin on mental health paramete... more Abstract Introduction: Data on comparison of myo-inositol and metformin on mental health parameters and biomarkers of oxidative stress in subjects with polycystic ovary syndrome (PCOS) are scarce. This purpose of this study was to compare of myo-inositol and metformin on mental health parameters and biomarkers of oxidative stress in subjects with PCOS. Methods: This randomized controlled trial was conducted among 60 subjects diagnosed with PCOS according to the Rotterdam criteria. Subjects were randomly assigned into two groups to intake either myo-inositol (n = 30) or metformin (n = 30) for 12 weeks. Parameters of mental health were recorded at baseline and after the 12-week intervention. Fasting blood samples were obtained at baseline and the end of the study to determine biomarkers of biomarkers of oxidative stress. Results: After the 12-week intervention, changes in beck depression inventory total score (−1.0 ± 1.7 vs. −0.3 ± 0.7, p = 0.03), general health questionnaire scores (−1.7 ± 2.9 vs. −0.5 ± 1.2, p = 0.02), depression anxiety and stress scale scores (−3.9 ± 6.4 vs. −0.9 ± 1.9, p = 0.01) and plasma total antioxidant capacity (TAC) concentrations (+106.1 ± 69.6 vs. +2.1 ± 132.4 mmol/L, p < 0.001) in the myo-inositol group were significantly different from the changes in these indicators in the metformin group. Myo-inositol supplementation for 12 weeks among patients with PCOS did not affect plasma glutathione and malondialdehyde levels. Conclusions: Overall, our data supported that myo-inositol supplementation for 12 weeks among patients with PCOS had favorable effects on parameters of mental health and plasma TAC levels.

Clinical Nutrition, 2018

Background and aims: The objective of this investigation was to assess the effects of probiotic a... more Background and aims: The objective of this investigation was to assess the effects of probiotic and selenium co-supplementation on indicators of mental health and metabolic profiles in diabetic people with coronary heart disease (CHD). Methods: This randomized, double-blind, placebo-controlled trial was conducted among 54 diabetic people with CHD. Patients were randomly allocated into two groups to receive either 200 mg/day selenium plus 8 Â 10 9 CFU/day probiotic (n ¼ 27) or placebo (n ¼ 27) for 12 weeks.

Journal of affective disorders, Mar 15, 2018

The aim of this study was to evaluate the effects of omega-3 and vitamin E co-supplementation on ... more The aim of this study was to evaluate the effects of omega-3 and vitamin E co-supplementation on parameters of mental health and gene expression related to insulin and inflammation in subjects with polycystic ovary syndrome (PCOS). Forty PCOS women were allocated into two groups and treated with 1000mg omega-3 fatty acids plus 400 IU vitamin E supplements (n = 20) or placebo (n = 20) per day for 12 weeks. Parameters of mental health were recorded at baseline and after the 12-week intervention. Gene expression related to insulin and inflammation were measured in blood samples of PCOS women. After the 12-week intervention, compared with the placebo, omega-3 and vitamin E co-supplementation led to significant improvements in beck depression inventory total score (- 2.2 ± 2.0 vs. - 0.2 ± 1.3, P = 0.001), general health questionnaire scores (- 5.5 ± 4.6 vs. - 1.0 ± 2.3, P < 0.001) and depression anxiety and stress scale scores (- 7.2 ± 5.2 vs. - 1.3 ± 1.3, P < 0.001). Compared with...

Gynecological Endocrinology, 2017

Introduction: Limited data are available assessing the effects of oral carnitine supplementation ... more Introduction: Limited data are available assessing the effects of oral carnitine supplementation on mental health parameters and biomarkers of oxidative stress of women with polycystic ovary syndrome (PCOS).This study was designed to determine the effects of oral carnitine supplementation on mental health parameters and biomarkers of oxidative stress in women with PCOS. Methods: In the current randomized, double-blind, placebo-controlled trial, 60 patients diagnosed with PCOS were randomized to take either 250 mg carnitine supplements (n ¼ 30) or placebo (n ¼ 30) for 12 weeks. Results: After 12 weeks' intervention, compared with the placebo, carnitine supplementation resulted in a significant improvement in Beck Depression Inventory total score (À2.7 ± 2.3 versus À0.2 ± 0.7, p50.001), General Health Questionnaire scores (À6.9 ± 4.9 versus À0.9 ± 1.5, p50.001) and Depression Anxiety and Stress Scale scores (À8.7 ± 5.9 versus À1.2 ± 2.9, p ¼ 0.001). In addition, changes in plasma total antioxidant capacity (TAC) (+84.1 ± 151.8 versus +4.6 ± 64.5 mmol/L, p ¼ 0.01), malondialdehyde (MDA) (À0.4 ± 1.0 versus +0.5 ± 1.5 mmol/L, p ¼ 0.01) and MDA/TAC ratio (À0.0005 ± 0.0010 versus +0.0006 ± 0.0019, p ¼ 0.003) in the supplemented group were significantly different from the changes in these indicators in the placebo group. Conclusions: Overall, our study demonstrated that carnitine supplementation for 12 weeks among patients with PCOS had favorable effects on parameters of mental health and biomarkers of oxidative stress.

European Psychiatry, 2011

IntroductionInfertility affects life of couples and family function. Infertility can cause mental... more IntroductionInfertility affects life of couples and family function. Infertility can cause mental disturbances in some studies.AimsThe goal of this study was the comparison of mental health in fertile and infertile women.MethodsA case-control study was done in Arak-Iran, Taleghani hospital which is a center of Gynecology, in 2010. 60 infertile women as case group and 60 fertile women as control group participated in the study, randomly. Both groups were assessed by GHQ questionnaire and data were analyzed by T-Test and logistic regression.ResultsThe severity of mental disturbances were much more in infertile women (P < 0.001). Social dysfunction (P < 0.001) and somatic complaints (P < 0.001) were also higher in infertile women. The probability of mental disturbances was much higher in infertile women (P < 0.001 and OR = 5.57).ConclusionMental health of infertile women is very critical and disturbed. The findings of our study necessitate the multidimensional interventions...

APOS Trends in Orthodontics, 2015

Objective Improvement in appearance is an important motivation for orthodontic treatment; neverth... more Objective Improvement in appearance is an important motivation for orthodontic treatment; nevertheless, not all patients with malocclusion seek treatment; therefore, the aim of this study was to compare the psychological state of patients with moderate to severe malocclusion who seek orthodontic treatment with patients who suffer from similar malocclusion but do not seek treatment. Materials and Methods Minnesota multiphasic personality inventory-2 questionnaire which assesses psychological states of people were given to 100 subject with moderate to severe malocclusion who were undergoing orthodontic treatment and 100 subjects with similar malocclusion who did not request orthodontic treatment. All subjects had similar demographic variables. Clinical scales measured by the test included: Hypochondriasis, depression, hysteria, psychopathic deviate, paranoia, psychasthenia, schizophrenia, and hypomania. The questionnaire consisted of 71 questions, and the subjects had to mark “True” o...