Hassan Hadi - Academia.edu (original) (raw)

Papers by Hassan Hadi

Baghdad Science Journal, 2008

Cholinesterases are among the most efficient enzymes known. They are divided into two groups: ace... more Cholinesterases are among the most efficient enzymes known. They are divided into two groups: acetylcholinesterase (AChE) involved in the hydrolysis of the neurotransimitter acetylcholine, and butyrylcholinesterase (BChE) of unknown function. Several crystal structures of the former have shown that the active site is located at the bottom of a deep and narrow gorge. Human BChE has attracted attention because it can hydrolyze toxic esters and nerve agents. Here we analyze the complexes of cholinesterase with soman by describing the 3D geometry of the complex, the active site, the changes happened through the inhibition and provide a description for the mechanism of inhibition. Soman undergoes degradation in the active site of the AChE and BChE. We calculate the energy of the products of the degradation reaction and suggest the reaction path. The product of the former reaction bind to serine residue in the active site and forming a stable bond and ends the catalytic function of the en...

Journal of Al-Nahrain University Science

Molecular dynamics (MD) simulations were carried out in order to investigate the binding mode of ... more Molecular dynamics (MD) simulations were carried out in order to investigate the binding mode of axillaridine-A at the active site of human acetylcholinesterase (AChE) enzyme. 2.0 nanosecond of MD simulations was made for the protein and the complex to dynamically explore the active site and the behavior of the ligand at the peripheral AChE binding site. These calculations for the enzyme alone showed that the active site of AChE is located at the bottom of a deep and narrow cavity whose surface is lined with rings of aromatic residues and Tyr72 is almost perpendicular to the Trp286 ring and forms a stable - interaction. The size of the active site of the complex decreases with time due to increase the interaction. Axillaridine-A forms in addition to van der Waals interactions, stable - interaction with the aromatic ring of Tyr117 residue which is responsible for the inhibition of the catalytic activity of the enzyme. Finally because of the biological relevance of the target studied here, the present results can be of interest for the rational design of molecules potentially useful in the treatment of the Alzheimer's disease.

Al-Mustansiriyah Journal of Science, 2017

The security of data storage in “cloud” is big challenge because the data keep within resources t... more The security of data storage in “cloud” is big challenge because the data keep within resources that may be accessed by particular machines. The managing of these data and services may not be high reliable. Therefore, the security of data is highly challenging. To increase the security of data in data center of cloud, we have introduced good method to ensure data security in “cloud computing” by methods of data hiding using color images which is called steganography. The fundamental objective of this paper is to prevent "Data Access” by unauthorized or opponent users. This scheme stores data at data centers within edges of color images and retrieves data from it when it is wanted.

Data from multi-temporal reflectance from optical sensors are integrated into a Geographic Inform... more Data from multi-temporal reflectance from optical sensors are integrated into a Geographic Information System (GIS) for monitoring vegetation with NDVI and its classification at the Tahaddart watershed (northwestern Rif, Morocco), during the winter season (high rainfall), spring and summer (low or no rainfall). The average values of this index vary according to wet seasons and dry seasons. The NDVI values classification shows that the forest zone of the Tahaddart basin central part doesn't show significant changes in the area. For this basin, a well-marked link has been highlighted in the annual change in NDVI and rainfall especially during the rainy season with an average linear correlation coefficient of 0.7268. These data show that climate variability is generally a key factor in the evolution of vegetation cover

Tectonophysics, 2005

By confronting different geological and geophysical data, we attempt to reconstruct the Variscan-... more By confronting different geological and geophysical data, we attempt to reconstruct the Variscan-Alleghanian orogenic belt, with especial emphasis on the links between Iberia, northwest Africa, and northeast America. The northern Iberia transect corresponds to the rifted margin of Gondwana, inverted during the Variscan orogeny and overthrust in its westernmost sector by a pile of allochthonous units, some of them with oceanic affinity and witnessing an orogenic suture. The southern Iberia section reveals two sutures at both boundaries of a terrane closely tied to Gondwana, namely the Ossa-Morena Zone. The southern boundary of this zone (i.e., the contact with the South Portuguese Zone) is enhanced by amphibolites with oceanic affinity and probably represents the suture of the Rheic Ocean. The Moroccan Variscides can be divided into: (i) a western external zone, namely the Coastal Block and the Central Massif; (ii) an internal zone, namely the Eastern Meseta; (iii) an eastern external zone represented in the Anti Atlas region; and (iv) the African cratonic foreland. Since neither ophiolites nor eclogites crop out along this transect of the orogen, we consider it to be an incomplete transect, lacking the main suture zone (Rheic Ocean). Stratigraphic and faunal affinities between the Moroccan Meseta, on the one hand, and the Central Iberian, Western Asturian-Leonese, and Cantabrian zones of Iberia, on the other hand, suggest that they may well have been part of a common pre-orogenic domain at the margin of Gondwana. On the contrary, there are no counterparts in Morocco for the Ossa-Morena Zone. Thus, the northern Iberia palaeogeographic zones would prolong in the Moroccan Meseta through an eastward arcuate structure, while the suture of the Rheic Ocean would do so offshore Morocco. In our reconstruction, an Avalonian spur (Grand Banks indentor), which included the Caledonian Sehoul block in northern Morocco and the crust of the South Portuguese Zone in SW Iberia, played an important role on the kinematic evolution of the orogen as well as on the final configuration of the

Journal of African Earth Sciences, 2010

... c Département de Géologie, Faculté des sciences Ben Msik-Sidi Othmane, BP 7955, Casablanca, M... more ... c Département de Géologie, Faculté des sciences Ben Msik-Sidi Othmane, BP 7955, Casablanca, Morocco. ... area showing, from north to south, the Sehoul block, the Sehoul thrust, the Bou Regreg corridor and the Sidi Bettache Carboniferous basin (from El Hassani (1991 ...

Journal of African Earth Sciences, 2007

The Oulmès granite is a NE–SW elongated stock intruded in Ordovician metasedimentary rocks which ... more The Oulmès granite is a NE–SW elongated stock intruded in Ordovician metasedimentary rocks which crop out at the core of a regional anticlinorium of the Moroccan Variscan Meseta. The stock, dated at around 300Ma, is made up of peraluminous two-mica granite, with subordinate amounts of muscovite leucogranite. Mineral composition and textural features of both the granite and the thermal aureole

Latar belakang. Latar belakang. Latar belakang. Latar belakang. Latar belakang. Obesitas pada ana... more Latar belakang. Latar belakang. Latar belakang. Latar belakang. Latar belakang. Obesitas pada anak dan remaja meningkatkan risiko penyakit degeneratif dan kardiovaskular. Namun belum jelas apakah remaja yang obesitas berisiko mengalami hiperlipidemia Tujuan. Tujuan. Tujuan. Tujuan. Tujuan. Menilai hubungan antara indeks masa tubuh (IMT), asupan karbohidrat dan lemak dengan hiperlipidemia pada murid SLTP yang obesitas. Metoda. Metoda. Metoda. Metoda. Metoda. Penelitian cross sectional di Yogyakarta. Sampel 109 murid SLTP dengan IMT = persentile-95 kurve IMT dari NCHS-CDC, dipilih secara acak dari murid SLTP yang obesitas, yang didapat pada survei obesitas secara cross sectional. Tinggi badan diukur dengan microtoise dan berat badan diukur dengan timbangan digital. Data asupan karbohidrat dan lemak diperoleh dari wawancara menggunakan FFQ periode 3 bulan terakhir. Hasil. Hasil. Hasil. Hasil. Hasil. Prevalensi obesitas murid SLTP 4,9%, hiperkolesterolemia 88,1% dan hipertrigliseridemia 100%. Asupan lemak berhubungan dengan kejadian hiperkolesterolemia (OR=6,48; KI 95%:2,80-15,02) dan hipertrigliseridemia (OR=5,31; KI 95%:2,34-12,07). Asupan karbohidrat juga berhubungan dengan kejadian hiperkolesterolemia (OR=5,43; KI 95%:1,85-15,92) dan hipertrigliseridemia (OR=3,71: KI 95%:1,34-10,27). IMT tidak berhubungan dengan kejadian hiperlipidemia. Kesimpulan. Kesimpulan. Kesimpulan. Kesimpulan. Kesimpulan. Peningkatan asupan lemak dan karbohidrat berhubungan dengan kejadian hiperlipidemia pada anak yang obesitas. Kata kunci: obesitas remaja, asupan zat gizi, indeks masa tubuh, hiperlipidemia.

... Bukitwetan P, Suryawidjaja JE, Salim OCh, Aidifiltif M, Lesmana M., Diare Bakterial: Etiologi... more ... Bukitwetan P, Suryawidjaja JE, Salim OCh, Aidifiltif M, Lesmana M., Diare Bakterial: Etiologi dan Pola Kepekaanl Antibiotika di Dua Pusat Kesehatan ... NB, Hamid AA, Santoso S., Diare Rotavirus padaAnak Di bawah Usia 3 Tahun yang Dirawat di RSU Dr. Saiful Anwar Malang ...

Objective: To explore the potential contribution of respiratory infections and vitamin A intakes ... more Objective: To explore the potential contribution of respiratory infections and vitamin A intakes to the seasonal effect of vitamin A supplementation on child growth. Methods: Data from a randomized double-blind placebo-controlled trial, in which a single high dose of vitamin A or placebo was given every 4 months to 1405 children aged 6-48 months were used for the analysis. In total, 4430 child-treatment cycles were examined, and for each cycle the children had their dietary intake, weight, and height assessed at the start and end. Linear regression models of the difference in height and weight during each treatment cycle were used and the within-child correlation was adjusted using the generalized estimating equations (GEE). Other covariables in the model included age, sex, percentage of days with acute lower respiratory infection and diarrhea, and cumulative doses of vitamin A. Results: This study showed that a significant effect of vitamin A supplementation on linear growth was observed in all seasons in children with a low burden of respiratory infections, that is, o21.5% of days with respiratory illness. In each season, the highest effect was found in children with a low burden of respiratory infections and low vitamin A intakes, that is, intakes o400 RE/day. Children with a high burden of respiratory infections or high vitamin A intakes benefited less from vitamin A supplementation for their linear growth than children with a low burden of respiratory infections and low vitamin A intakes. Finally, there was no benefit for linear growth from vitamin A supplementation in children with both a high burden of respiratory infections and high vitamin A intakes regardless of the season. Conclusions: The effect of vitamin A supplementation on growth is dependent on season. Respiratory infections and vitamin A intakes are important factors underlying the seasonal effect of vitamin A supplementation on growth.

There are a few people, especially parents, who care about the sex education of children. They as... more There are a few people, especially parents, who care about the sex education of children. They assumed that sex education is prohibited to be taught to children. Even though, early childhood sex education introduces the body parts and their functions to the children and able to prevent them from the crimes of sexual. This study aims to seek the factors associated with the level of parents knowledge of early sex education to the children at Kartika VIII-5 Elementary School, South Jakarta, in 2014. The result indicates that there is a significant relationship between education, social and cultural value, and exposure of information with the level of parents knowledge of sex education. Whereas, the occupation, age, and experience have no significant relationship with the level of parents knowledge of early sex education to the children.

Monocytes play a key role in cellular inflammatory response. However, it is not known how contras... more Monocytes play a key role in cellular inflammatory response. However, it is not known how contrast media modulate monocytes. There are diverge characteristics between different contrast media. In this experiment, we investigate the influence of adhesion molecule and apoptotic factors of monocytes by ionic (iothalamate, IOT) and non-ionic contrast media (iohexol, IOH). U937 (a human monocytic cell-line) was cultured in RPMI 1640 with 10% FCS at 37°C for 48 hours. These cells were then exposed to 4 series of concentration (0, 10, 50, 100 mgI/ml) of contrast medium for 30 minutes. Total RNA was extracted and converted to cDNA by commercial kit. RTPCR was performed in appropriate conditions to obtain the expression of ICAM-1, E-selectin, Fas and Bcl-2. β-actin was used as normalization. In this study, we demonstrate that E-selectin expression was increased at the concentration of 100mgI/ml both in IOT and IOH. However, ICAM-1 was constitutionally expressed and not changed by either contrast media. Expression of Fas was not significantly mediated either. Interestingly, the level of bcl-2 that has the antiapoptotic effect was decreased by both contrast media in dose-dependent manner. Furthermore, bcl-2 expression was suppressed more by IOH than IOT. Western blot showed that caspase-3 protein (the proapoptotic effect) was increased more significantly by IOH than IOH, even at 10mgI/ml. In summary, 1) both contrast media could induce E-selectin mRNA expression at high concentration. 2) Non-ionic IOH has the ability to induce more monocyte apoptosis with increased caspase-3 protein than ionic IOT does.

... Kata kunci, Anemia Gizi,Ibu Hamil,Epidemiologi GAKI. Deskripsi, viii, 83 p., bibl., ills., 29... more ... Kata kunci, Anemia Gizi,Ibu Hamil,Epidemiologi GAKI. Deskripsi, viii, 83 p., bibl., ills., 29 cm. Bahasa, Indonesia. Jenis, Thesis. Penerbit, [Yogyakarta] : Universitas Gadjah Mada, 2007. Lokasi, Perpustakaan Pusat UGM. File, Tidak tersedia. * Anda dapat mengecek ketersediaan versi ...

... Status GAKI berdasar pembesaran goiter berhubungan dengan menurunnya tingkat kecerdasan, seda... more ... Status GAKI berdasar pembesaran goiter berhubungan dengan menurunnya tingkat kecerdasan, sedangkan kecukupan konsumsi yodium berhubungan dengan penurunan ... Anda dapat mengecek ketersediaan versi cetak dari penelitian ini di Perpustakaan Pusat UGM Unit 3. ...

Geodinamica Acta, 2006

The present paper takes the Variscan granitoids of Morocco as the starting point for the discussi... more The present paper takes the Variscan granitoids of Morocco as the starting point for the discussion of broad correlations of magmatism along the Variscan orogenic belt. Remarkable differences stand out between the Western Moroccan Meseta (peraluminous granites) and the Eastern Moroccan Meseta (potassic to shoshonitic, calc-alkaline granitoids). In Iberia, the Variscan magmatism can be arranged into distinctive zones too, which have been compared with those in Morocco. Although two of these zones mimic the I-type and S-type subduction paired belts, the intrusion of the granitoids was mostly late-collisional. Calc-alkaline, metaluminous (I-type) potassic granitoids of the southern zone may reflect a source of enriched mantle (such an enrichment taking place during Devonian Variscan subduction or latest Precambrian subduction) and different degrees of crustal contamination. Considerable volumes of peraluminous S-type granites in the central magmatic zone reflect a widespread melting of...

Journal of African Earth Sciences, 2010

... c Département de Géologie, Faculté des sciences Ben Msik-Sidi Othmane, BP 7955, Casablanca, M... more ... c Département de Géologie, Faculté des sciences Ben Msik-Sidi Othmane, BP 7955, Casablanca, Morocco. ... area showing, from north to south, the Sehoul block, the Sehoul thrust, the Bou Regreg corridor and the Sidi Bettache Carboniferous basin (from El Hassani (1991 ...

Baghdad Science Journal, 2008

Cholinesterases are among the most efficient enzymes known. They are divided into two groups: ace... more Cholinesterases are among the most efficient enzymes known. They are divided into two groups: acetylcholinesterase (AChE) involved in the hydrolysis of the neurotransimitter acetylcholine, and butyrylcholinesterase (BChE) of unknown function. Several crystal structures of the former have shown that the active site is located at the bottom of a deep and narrow gorge. Human BChE has attracted attention because it can hydrolyze toxic esters and nerve agents. Here we analyze the complexes of cholinesterase with soman by describing the 3D geometry of the complex, the active site, the changes happened through the inhibition and provide a description for the mechanism of inhibition. Soman undergoes degradation in the active site of the AChE and BChE. We calculate the energy of the products of the degradation reaction and suggest the reaction path. The product of the former reaction bind to serine residue in the active site and forming a stable bond and ends the catalytic function of the en...

Journal of Al-Nahrain University Science

Molecular dynamics (MD) simulations were carried out in order to investigate the binding mode of ... more Molecular dynamics (MD) simulations were carried out in order to investigate the binding mode of axillaridine-A at the active site of human acetylcholinesterase (AChE) enzyme. 2.0 nanosecond of MD simulations was made for the protein and the complex to dynamically explore the active site and the behavior of the ligand at the peripheral AChE binding site. These calculations for the enzyme alone showed that the active site of AChE is located at the bottom of a deep and narrow cavity whose surface is lined with rings of aromatic residues and Tyr72 is almost perpendicular to the Trp286 ring and forms a stable - interaction. The size of the active site of the complex decreases with time due to increase the interaction. Axillaridine-A forms in addition to van der Waals interactions, stable - interaction with the aromatic ring of Tyr117 residue which is responsible for the inhibition of the catalytic activity of the enzyme. Finally because of the biological relevance of the target studied here, the present results can be of interest for the rational design of molecules potentially useful in the treatment of the Alzheimer's disease.

Al-Mustansiriyah Journal of Science, 2017

The security of data storage in “cloud” is big challenge because the data keep within resources t... more The security of data storage in “cloud” is big challenge because the data keep within resources that may be accessed by particular machines. The managing of these data and services may not be high reliable. Therefore, the security of data is highly challenging. To increase the security of data in data center of cloud, we have introduced good method to ensure data security in “cloud computing” by methods of data hiding using color images which is called steganography. The fundamental objective of this paper is to prevent "Data Access” by unauthorized or opponent users. This scheme stores data at data centers within edges of color images and retrieves data from it when it is wanted.

Data from multi-temporal reflectance from optical sensors are integrated into a Geographic Inform... more Data from multi-temporal reflectance from optical sensors are integrated into a Geographic Information System (GIS) for monitoring vegetation with NDVI and its classification at the Tahaddart watershed (northwestern Rif, Morocco), during the winter season (high rainfall), spring and summer (low or no rainfall). The average values of this index vary according to wet seasons and dry seasons. The NDVI values classification shows that the forest zone of the Tahaddart basin central part doesn't show significant changes in the area. For this basin, a well-marked link has been highlighted in the annual change in NDVI and rainfall especially during the rainy season with an average linear correlation coefficient of 0.7268. These data show that climate variability is generally a key factor in the evolution of vegetation cover

Tectonophysics, 2005

By confronting different geological and geophysical data, we attempt to reconstruct the Variscan-... more By confronting different geological and geophysical data, we attempt to reconstruct the Variscan-Alleghanian orogenic belt, with especial emphasis on the links between Iberia, northwest Africa, and northeast America. The northern Iberia transect corresponds to the rifted margin of Gondwana, inverted during the Variscan orogeny and overthrust in its westernmost sector by a pile of allochthonous units, some of them with oceanic affinity and witnessing an orogenic suture. The southern Iberia section reveals two sutures at both boundaries of a terrane closely tied to Gondwana, namely the Ossa-Morena Zone. The southern boundary of this zone (i.e., the contact with the South Portuguese Zone) is enhanced by amphibolites with oceanic affinity and probably represents the suture of the Rheic Ocean. The Moroccan Variscides can be divided into: (i) a western external zone, namely the Coastal Block and the Central Massif; (ii) an internal zone, namely the Eastern Meseta; (iii) an eastern external zone represented in the Anti Atlas region; and (iv) the African cratonic foreland. Since neither ophiolites nor eclogites crop out along this transect of the orogen, we consider it to be an incomplete transect, lacking the main suture zone (Rheic Ocean). Stratigraphic and faunal affinities between the Moroccan Meseta, on the one hand, and the Central Iberian, Western Asturian-Leonese, and Cantabrian zones of Iberia, on the other hand, suggest that they may well have been part of a common pre-orogenic domain at the margin of Gondwana. On the contrary, there are no counterparts in Morocco for the Ossa-Morena Zone. Thus, the northern Iberia palaeogeographic zones would prolong in the Moroccan Meseta through an eastward arcuate structure, while the suture of the Rheic Ocean would do so offshore Morocco. In our reconstruction, an Avalonian spur (Grand Banks indentor), which included the Caledonian Sehoul block in northern Morocco and the crust of the South Portuguese Zone in SW Iberia, played an important role on the kinematic evolution of the orogen as well as on the final configuration of the

Journal of African Earth Sciences, 2010

... c Département de Géologie, Faculté des sciences Ben Msik-Sidi Othmane, BP 7955, Casablanca, M... more ... c Département de Géologie, Faculté des sciences Ben Msik-Sidi Othmane, BP 7955, Casablanca, Morocco. ... area showing, from north to south, the Sehoul block, the Sehoul thrust, the Bou Regreg corridor and the Sidi Bettache Carboniferous basin (from El Hassani (1991 ...

Journal of African Earth Sciences, 2007

The Oulmès granite is a NE–SW elongated stock intruded in Ordovician metasedimentary rocks which ... more The Oulmès granite is a NE–SW elongated stock intruded in Ordovician metasedimentary rocks which crop out at the core of a regional anticlinorium of the Moroccan Variscan Meseta. The stock, dated at around 300Ma, is made up of peraluminous two-mica granite, with subordinate amounts of muscovite leucogranite. Mineral composition and textural features of both the granite and the thermal aureole

Latar belakang. Latar belakang. Latar belakang. Latar belakang. Latar belakang. Obesitas pada ana... more Latar belakang. Latar belakang. Latar belakang. Latar belakang. Latar belakang. Obesitas pada anak dan remaja meningkatkan risiko penyakit degeneratif dan kardiovaskular. Namun belum jelas apakah remaja yang obesitas berisiko mengalami hiperlipidemia Tujuan. Tujuan. Tujuan. Tujuan. Tujuan. Menilai hubungan antara indeks masa tubuh (IMT), asupan karbohidrat dan lemak dengan hiperlipidemia pada murid SLTP yang obesitas. Metoda. Metoda. Metoda. Metoda. Metoda. Penelitian cross sectional di Yogyakarta. Sampel 109 murid SLTP dengan IMT = persentile-95 kurve IMT dari NCHS-CDC, dipilih secara acak dari murid SLTP yang obesitas, yang didapat pada survei obesitas secara cross sectional. Tinggi badan diukur dengan microtoise dan berat badan diukur dengan timbangan digital. Data asupan karbohidrat dan lemak diperoleh dari wawancara menggunakan FFQ periode 3 bulan terakhir. Hasil. Hasil. Hasil. Hasil. Hasil. Prevalensi obesitas murid SLTP 4,9%, hiperkolesterolemia 88,1% dan hipertrigliseridemia 100%. Asupan lemak berhubungan dengan kejadian hiperkolesterolemia (OR=6,48; KI 95%:2,80-15,02) dan hipertrigliseridemia (OR=5,31; KI 95%:2,34-12,07). Asupan karbohidrat juga berhubungan dengan kejadian hiperkolesterolemia (OR=5,43; KI 95%:1,85-15,92) dan hipertrigliseridemia (OR=3,71: KI 95%:1,34-10,27). IMT tidak berhubungan dengan kejadian hiperlipidemia. Kesimpulan. Kesimpulan. Kesimpulan. Kesimpulan. Kesimpulan. Peningkatan asupan lemak dan karbohidrat berhubungan dengan kejadian hiperlipidemia pada anak yang obesitas. Kata kunci: obesitas remaja, asupan zat gizi, indeks masa tubuh, hiperlipidemia.

... Bukitwetan P, Suryawidjaja JE, Salim OCh, Aidifiltif M, Lesmana M., Diare Bakterial: Etiologi... more ... Bukitwetan P, Suryawidjaja JE, Salim OCh, Aidifiltif M, Lesmana M., Diare Bakterial: Etiologi dan Pola Kepekaanl Antibiotika di Dua Pusat Kesehatan ... NB, Hamid AA, Santoso S., Diare Rotavirus padaAnak Di bawah Usia 3 Tahun yang Dirawat di RSU Dr. Saiful Anwar Malang ...

Objective: To explore the potential contribution of respiratory infections and vitamin A intakes ... more Objective: To explore the potential contribution of respiratory infections and vitamin A intakes to the seasonal effect of vitamin A supplementation on child growth. Methods: Data from a randomized double-blind placebo-controlled trial, in which a single high dose of vitamin A or placebo was given every 4 months to 1405 children aged 6-48 months were used for the analysis. In total, 4430 child-treatment cycles were examined, and for each cycle the children had their dietary intake, weight, and height assessed at the start and end. Linear regression models of the difference in height and weight during each treatment cycle were used and the within-child correlation was adjusted using the generalized estimating equations (GEE). Other covariables in the model included age, sex, percentage of days with acute lower respiratory infection and diarrhea, and cumulative doses of vitamin A. Results: This study showed that a significant effect of vitamin A supplementation on linear growth was observed in all seasons in children with a low burden of respiratory infections, that is, o21.5% of days with respiratory illness. In each season, the highest effect was found in children with a low burden of respiratory infections and low vitamin A intakes, that is, intakes o400 RE/day. Children with a high burden of respiratory infections or high vitamin A intakes benefited less from vitamin A supplementation for their linear growth than children with a low burden of respiratory infections and low vitamin A intakes. Finally, there was no benefit for linear growth from vitamin A supplementation in children with both a high burden of respiratory infections and high vitamin A intakes regardless of the season. Conclusions: The effect of vitamin A supplementation on growth is dependent on season. Respiratory infections and vitamin A intakes are important factors underlying the seasonal effect of vitamin A supplementation on growth.

There are a few people, especially parents, who care about the sex education of children. They as... more There are a few people, especially parents, who care about the sex education of children. They assumed that sex education is prohibited to be taught to children. Even though, early childhood sex education introduces the body parts and their functions to the children and able to prevent them from the crimes of sexual. This study aims to seek the factors associated with the level of parents knowledge of early sex education to the children at Kartika VIII-5 Elementary School, South Jakarta, in 2014. The result indicates that there is a significant relationship between education, social and cultural value, and exposure of information with the level of parents knowledge of sex education. Whereas, the occupation, age, and experience have no significant relationship with the level of parents knowledge of early sex education to the children.

Monocytes play a key role in cellular inflammatory response. However, it is not known how contras... more Monocytes play a key role in cellular inflammatory response. However, it is not known how contrast media modulate monocytes. There are diverge characteristics between different contrast media. In this experiment, we investigate the influence of adhesion molecule and apoptotic factors of monocytes by ionic (iothalamate, IOT) and non-ionic contrast media (iohexol, IOH). U937 (a human monocytic cell-line) was cultured in RPMI 1640 with 10% FCS at 37°C for 48 hours. These cells were then exposed to 4 series of concentration (0, 10, 50, 100 mgI/ml) of contrast medium for 30 minutes. Total RNA was extracted and converted to cDNA by commercial kit. RTPCR was performed in appropriate conditions to obtain the expression of ICAM-1, E-selectin, Fas and Bcl-2. β-actin was used as normalization. In this study, we demonstrate that E-selectin expression was increased at the concentration of 100mgI/ml both in IOT and IOH. However, ICAM-1 was constitutionally expressed and not changed by either contrast media. Expression of Fas was not significantly mediated either. Interestingly, the level of bcl-2 that has the antiapoptotic effect was decreased by both contrast media in dose-dependent manner. Furthermore, bcl-2 expression was suppressed more by IOH than IOT. Western blot showed that caspase-3 protein (the proapoptotic effect) was increased more significantly by IOH than IOH, even at 10mgI/ml. In summary, 1) both contrast media could induce E-selectin mRNA expression at high concentration. 2) Non-ionic IOH has the ability to induce more monocyte apoptosis with increased caspase-3 protein than ionic IOT does.

... Kata kunci, Anemia Gizi,Ibu Hamil,Epidemiologi GAKI. Deskripsi, viii, 83 p., bibl., ills., 29... more ... Kata kunci, Anemia Gizi,Ibu Hamil,Epidemiologi GAKI. Deskripsi, viii, 83 p., bibl., ills., 29 cm. Bahasa, Indonesia. Jenis, Thesis. Penerbit, [Yogyakarta] : Universitas Gadjah Mada, 2007. Lokasi, Perpustakaan Pusat UGM. File, Tidak tersedia. * Anda dapat mengecek ketersediaan versi ...

... Status GAKI berdasar pembesaran goiter berhubungan dengan menurunnya tingkat kecerdasan, seda... more ... Status GAKI berdasar pembesaran goiter berhubungan dengan menurunnya tingkat kecerdasan, sedangkan kecukupan konsumsi yodium berhubungan dengan penurunan ... Anda dapat mengecek ketersediaan versi cetak dari penelitian ini di Perpustakaan Pusat UGM Unit 3. ...

Geodinamica Acta, 2006

The present paper takes the Variscan granitoids of Morocco as the starting point for the discussi... more The present paper takes the Variscan granitoids of Morocco as the starting point for the discussion of broad correlations of magmatism along the Variscan orogenic belt. Remarkable differences stand out between the Western Moroccan Meseta (peraluminous granites) and the Eastern Moroccan Meseta (potassic to shoshonitic, calc-alkaline granitoids). In Iberia, the Variscan magmatism can be arranged into distinctive zones too, which have been compared with those in Morocco. Although two of these zones mimic the I-type and S-type subduction paired belts, the intrusion of the granitoids was mostly late-collisional. Calc-alkaline, metaluminous (I-type) potassic granitoids of the southern zone may reflect a source of enriched mantle (such an enrichment taking place during Devonian Variscan subduction or latest Precambrian subduction) and different degrees of crustal contamination. Considerable volumes of peraluminous S-type granites in the central magmatic zone reflect a widespread melting of...

Journal of African Earth Sciences, 2010

... c Département de Géologie, Faculté des sciences Ben Msik-Sidi Othmane, BP 7955, Casablanca, M... more ... c Département de Géologie, Faculté des sciences Ben Msik-Sidi Othmane, BP 7955, Casablanca, Morocco. ... area showing, from north to south, the Sehoul block, the Sehoul thrust, the Bou Regreg corridor and the Sidi Bettache Carboniferous basin (from El Hassani (1991 ...