Rafikah Hasyim - Academia.edu (original) (raw)

Papers by Rafikah Hasyim

Research paper thumbnail of The effectiveness of game-based education on dental and oral health behavior: Systematic review

The skill of brushing teeth has a significant role in preventing dental caries. To improve teeth ... more The skill of brushing teeth has a significant role in preventing dental caries. To improve teeth brushing skills. Health education is needed for children from an early age. Educational media determine the effectiveness of children's learning. So there needs to be treated using android-based educational game media to attract students' attention to learning. Objective: To determine the effectiveness of Game-Based Education on Dental and Oral Health Behavior in Literature Review Results: Of the 11 works of literature reviewed, 7 of them discussed changes in dental and oral health, with 6 showing positive results and one literature showing negative results, but the literature still shows an improvement in oral health, but not significantly. These results can be obtained due to the lack of samples and short observation times. However, 6 of the literature reviewed showed favorable oral health conditions. Conclusion: This paper presents a review of several pieces of literature that highlight the effectiveness of game-based education on oral health behavior. The literature obtained generally shows positive results in increasing knowledge and behavior of oral health.

Research paper thumbnail of Efficacy of Stigma maydis (Corn silk) in Reducing Blood Sugar Level and Subduing Periodontal Inflammation

Systematic Reviews in Pharmacy, 2020

Diabetes is one of the most common non-communicable diseases in the world, according to the World... more Diabetes is one of the most common non-communicable diseases in the world, according to the World Health Organization (WHO). Diabetes is a complex chronic disease with many side complications; one of them is periodontitis or periodontal tissue inflammation. The two are linked to each other by a high blood glucose level. The purpose of this research was to discern the efficacy of Stigma maydis extract as a topical medication to decrease hyperglycemia also subdues periodontal tissue inflammation. Fifteen Male Wistar rats were included in this study, and the periodontitis model was induced using ligatures tied in lower first incisors; also, alloxan was used to create a diabetes mellitus model in the study animals. The result showed that blood sugar level in Fa group was unsteady (p >0.05), and there was an increase in the blood glucose level after a decrease, while both Fb and Fc groups showed stable blood glucose decrease (p<0.05). Fc managed to subdue the inflammation with mild inflammation results (p<0.05), while both Fa & Fb showed less effect with only moderate inflammation (p>0.05). From this study, it can be concluded that topically administered corn silk extract is efficient in reducing blood sugar levels and subduing periodontal tissue inflammation in diabetes-induced albino rats.

Research paper thumbnail of Where Microneedle Meets Biomarkers: Futuristic Application for Diagnosing and Monitoring Localized External Organ Diseases (Adv. Healthcare Mater. 5/2023)

Advanced Healthcare Materials, Feb 1, 2023

Research paper thumbnail of The effectiveness of game-based education on dental and oral health behavior: Systematic review

Open Journal of Clinical and Medical Images

Preliminary: The skill of brushing teeth has a significant role in preventing dental caries. To i... more Preliminary: The skill of brushing teeth has a significant role in preventing dental caries. To improve teeth brushing skills. Health education is needed for children from an early age. Educational media determine the effectiveness of childrens learning. So there needs to be treated using android-based educational game media to attract students attention to learning.

Research paper thumbnail of Where Microneedle Meets Biomarkers: Futuristic Application for Diagnosing and Monitoring Localized External Organ Diseases

Advanced Healthcare Materials

Extracellular tissue fluids are interesting biomatrices that have recently attracted scientists&#... more Extracellular tissue fluids are interesting biomatrices that have recently attracted scientists' interest. Many significant biomarkers for localized external organ diseases have been isolated from this biofluid. In the diagnostic and disease monitoring context, measuring biochemical entities from the fluids surrounding the diseased tissues may give more important clinical value than measuring them at a systemic level. Despite all these facts, pushing tissue fluid‐based diagnosis and monitoring forward to clinical settings faces one major problem: its accessibility. Most extracellular tissue fluid, such as interstitial fluid (ISF), is abundant but hard to collect, and the currently available technologies are invasive and expensive. This is where novel microneedle technology can help tackle this significant obstacle. The ability of microneedle technology to minimally invasively access tissue fluid‐containing biomarkers will enable ISF and other tissue fluid utilization in the clin...

Research paper thumbnail of The Hard Tissue Lesions Associated with Impacted Teeth

Systematic Reviews in Pharmacy, 2020

This Radiography helps a dentist to evaluate the condition of hard tissue in the oral cavity. Rad... more This Radiography helps a dentist to evaluate the condition of hard tissue in the oral cavity. Radiography is one of the tools to establish the diagnosis of impacted teeth and the accompanied hard tissue lesions. Lesions that could accompany impacted teeth not only caries lesions but also lesions that extend into the jaw region. The purpose of this study was to determine the prevalence of impacted teeth accompanied by hard tissue lesions at Dental and Oral Hospital of Hasanuddin University based on panoramic radiography. This research was descriptive observational with consecutive sampling. The study population was all panoramic radiography data of patients aged 21-40 years that viewed from the medical record data from 2016-2017. Data obtained then processed in table form. The result showed that the frequency of impacted occurrence based on its location, 56.2%, occurs in the mandible. Impacted teeth that accompanied by caries was 53.4%, the periapical abscess was 28.8%, and the dentigerous cyst was 17.8%. The conclusion indicated that almost every case of impacted would be accompanied by a hard tissue lesion, either caries lesion or a lesion that extends into the jaw.

Research paper thumbnail of The Effect of Low Bone Mineral Density in Stomatognatic System

Osteoporosis is a systemic bone disease that characterized by low bone mineral density. The study... more Osteoporosis is a systemic bone disease that characterized by low bone mineral density. The study was aimed to determine the relationship between bone mineral density status with the severity of periodontal disease and tooth loss. The study was conducted on patients who come to RSUP.DR.Wahidin Sudiro Husodo with the sample size is 33 people. After completing dental records, each oral cavity of the sampleswas examine of by using a panoramic dental x-ray to see the level of alveolar bone resorption. A complete blood laboratory test was performed to value calcium serum. Examination of bone mineral density conducted at the lumbal spine and the femoral head by using DXA. The results show that low levels of BMD to periodontal status showed a significant result (p = 0.005). The level of bone resorption occured greater in mandible than in maxilla. However, calcium serum levels showed no significant results in the low BMD (p> 0.005). In addition, there were no statistically significant re...

Research paper thumbnail of Efficacy of Stigma maydis (Corn silk) in Reducing Blood Sugar Level and Subduing Periodontal Inflammation

Systematic Reviews in Pharmacy, 2020

Diabetes is one of the most common non-communicable diseases in the world, according to the World... more Diabetes is one of the most common non-communicable diseases in the world, according to the World Health Organization (WHO). Diabetes is a complex chronic disease with many side complications; one of them is periodontitis or periodontal tissue inflammation. The two are linked to each other by a high blood glucose level. The purpose of this research was to discern the efficacy of Stigma maydis extract as a topical medication to decrease hyperglycemia also subdues periodontal tissue inflammation. Fifteen Male Wistar rats were included in this study, and the periodontitis model was induced using ligatures tied in lower first incisors; also, alloxan was used to create a diabetes mellitus model in the study animals. The result showed that blood sugar level in Fa group was unsteady (p >0.05), and there was an increase in the blood glucose level after a decrease, while both Fb and Fc groups showed stable blood glucose decrease (p

Research paper thumbnail of Analysis of first permanent molar condition on Kindergarten student aged 5-6 years old in Eastern Suburban Area of Makassar City

Journal of Dentomaxillofacial Science, 2020

The aim of this study was to analyze the first permanent molar condition on kindergarten student ... more The aim of this study was to analyze the first permanent molar condition on kindergarten student aged 5-6 years old in eastern suburban area of Makassar city. Material and methods: This study was a descriptive observational study on 100 kindergarten students from four schools in Tamalanrea District, Makassar City. Data was collected with clinical examination and interview. Data was gathered in terms of DMFT status of first permanent molar and OHI-S. Data was analyzed with descriptive statistics and t-test. In this descriptive cross-sectional study. Statistical analysis was performed by descriptive statistics and t-test. statistics and t-test. In this descriptive cross-sectional study. Statistical analysis was performed by descriptive statistics and t-test. Results: Mean DMFT of first permanent molars was 1.00 ± 1.10, with a higher value seen among boys. Mean decayed teeth component was 0.95, followed by filled (0.10) and missing (0.0) components. Conclusion: The observed oral hygiene status among the 5-6 yearolds necessitates implementing preventive as well as restorative measures to improve the oral health status of the young population.

Research paper thumbnail of Oral mucosa lesion prevalence at Department of Oral Medicine, Halimah Daeng Sikati dental hospital in Makassar

Journal of Dentomaxillofacial Science, 2016

Objective: To compare the effects of platelet-rich fibrin (PRF) and connective tissue graft (CTG)... more Objective: To compare the effects of platelet-rich fibrin (PRF) and connective tissue graft (CTG) in gingival recession treatment using coronally advanced flap (CAF) Methods: Electronic Pubmed, Wiley, and EMBASE searches were conducted to identify articles published in dental journals without any restrictions of publication date. Gingival Recession Depth (RD), Keratinized Tissue Width (KTW), Probing Depth (PD), Clinical Attachment Level (CAL) and % Complete Root Coverage (CRC) were evaluated at baseline and 6 months. Patients with discomfort postsurgery was measured by comparing Visual Analog Scale (VAS) scores. Manual searches of human clinical trial and related articles were performed afterward. There are 31 studies explained about this, but only 6 studies met the inclusion criteria. Results: The initial database search produced 221 titles. All articles were selected for full-text review. Six studies were selected for inclusion, with 88 patients as subjects. Most of the studies showed the decreased of RD, PD, CAL and the increased of KTW in both techniques at baseline and 6 months follow up. The percentage of CRC showed higher in CTG rather than PRF whereas VAS score showed lower in PRF group Conclusion: Both PRF + CAF and CTG + CAF techniques are effective procedures in the treatment of gingival recession. The combination of CAF+CTG achieved a better result in root coverage however, PRF avoids a donor site, which means a major decrease in postoperative discomfort.

Research paper thumbnail of Saliva parameter analysis on smoker and non smoker patients exposed to intraoral radiography

Objective: To analyze saliva parameter such as salivary pH, total protein, buffer capacity, as we... more Objective: To analyze saliva parameter such as salivary pH, total protein, buffer capacity, as well as sodium and potassium level on smoker and non smoker patients after exposed to intraoral radiography. Material and Methods: This study was an observational study with cross-sectional design. Samples were smoker and non smoker patients who were referred to Dental Hospital Hasanuddin University. Saliva samples were taken by draining method. Samples were transferred immediately to Laboratory of Biochemistry, Faculty of Mathematics and Science to be processed regarding saliva pH, saliva total protein, buffer capacity, as well as saliva sodium and potassium level. Saliva pH were measured with pH meter Hanna instruments, total protein with Lowry’s method, buffer capacity with Ericcson’s method, sodium and potassium level with atomic absorption spectrophotometer Parking Elmer A400. Data were then analyzed with statistical test Kolmogorov Smirnov, independent t-test, and oneway Anova with p...

Research paper thumbnail of An Analysis of Dental Enamel after Bleaching using 35% Hydrogen Peroxide with Energy-dispersive X-ray Spectroscopy

World Journal of Dentistry, 2017

Introduction: Hydrogen peroxide (H 2 O 2) is an effective bleaching agent of tooth whitening, but... more Introduction: Hydrogen peroxide (H 2 O 2) is an effective bleaching agent of tooth whitening, but its use causes changes in the chemical composition of the elements that configure tooth enamel. The purpose of this study is to determine whether there are changes in the composition of the elements that configure the tooth enamel after bleaching using 35% H 2 O 2. Materials and methods: This study was performed in vitro, which is an experimental research laboratory with controlled time series design. The samples used in this study were six permanent incisors postextraction and are divided into treatment and control groups. The control group was soaked in saline and treatment groups applied with H 2 O 2 35%, with time series of 1, 1.5, 2, 2.5, and 3 hours. The elemental composition of enamel was observed using energy-dispersive X-ray spectroscopy analysis; results can be obtained both qualitatively and quantitatively. This study was analyzed using non-parametric test (Kruskal-Wallis test) to determine changes in enamel composition after bleaching, whether there is a change in enamel composition or not. Results: The results of this study showed a p-value of 0.406 (p < 0.05; significant). The result shows a change in the composition of dental enamel after bleaching using 35% H 2 O 2. Conclusion: Application of 35% H 2 O 2 as the bleaching agent does not have a significant influence on changes in the composition of the elements contained in the enamel.

Research paper thumbnail of The analysis of accelerator concentration effect on setting time and morphology surface impression materials made of brown algae Sargassum sp

Medicina clínica práctica, Jun 1, 2020

Objective: To analyze the accelerator concentration on alginate impression material setting time ... more Objective: To analyze the accelerator concentration on alginate impression material setting time made of brown algae Sargassum sp. Method: This study was an experimental laboratory using samples of impression material made of brown algae Sargassum sp. Measurement of setting time using stopwatch and morphological surface analysis using Scanning Electron Magnetic (SEM). Result: The average setting time for the fastest calcium sulfate accelerator is 3.11 min (17 g) and the longest is 6.13 min (15 g). As for the fastest potassium titanium fluoride accelerator material the timeline setting is 3.81 min (4 g) and the longest is 5.73 min (2 g). SEM analysis showed that alginate printing impression materials with accelerator materials of calcium sulfate 17 g and potassium titanium fluoride 4 g showed the smaller, finer denser and more homogenous surface morphology. Conclusion: Impression material made of Sargassum sp. with accelerator calcium sulfate 17 g and potassium titanium fluoride 4 g has a better setting time and surface morphology.

Research paper thumbnail of Comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptide-amorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material

Journal of dentomaxillofacial science, Dec 1, 2018

The aim of this study was to determine the comparison of blood clam (anadara granosa) shell paste... more The aim of this study was to determine the comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptideamorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material. Material and Methods: This study was an experimental laboratory with cross sectional design. Study sample was 15 maxillary central incisors that were applied with 35% hydrogen peroxide for 2 hours, then assessed with Energy Dispersive Spectroscopy (EDS). Samples were divided into 3 groups: 5 samples were applied using blood clam (anadara granosa) shell paste, 5 samples using shrimp shell paste and 5 samples were applied using CPP-ACP paste every 8 hours for 14 consecutive days then checked with EDS. Data analysis using SPSS test independent t-test to see comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptide-amorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material. Results: The result of this study showed P> 0.05 which means there was no significant difference between blood clam shell paste, shrimp shell paste and CPP-ACP mineral composition. Conclusion: Blood clam shell paste and shrimp shell paste has an effective value to be used as tooth remineralization material.

Research paper thumbnail of The Effect of Oral Health Status on Elderly Quality of Life in Makassar District, Indonesia

Systematic Reviews in Pharmacy, 2020

The objective of this study is to determine the effect of oral health status on the quality of li... more The objective of this study is to determine the effect of oral health status on the quality of life of older people living with families in Tamalanrea District, Makassar. This study was an observational analytic study with a cross-sectional design. The study was conducted on 268 elderly samples, dental and oral health status was measured using the OHI-S index and DMF-T. The level of quality of life was measured by GOHAI. The study showed that caries affected the quality of life of the elderly (p = 0.000), oral hygiene affected the quality of life of the elderly (p = 0.001), tooth loss affected the quality of life of the elderly (p = 0.000), and using dentures affected the quality living elderly (p = 0.000). Based on the study conducted, there is an effect of dental and oral health status on the quality of life of elderly living with families in Tamalanrea District, Makassar.

Research paper thumbnail of Comparison of Shrimp (Litopenaeus Vannamei) Shell Paste and Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-Acp) Paste as Teeth Remineralization Material

Objective: To determine the comparison of shrimp shell and casein phosphopeptide-amorphous calciu... more Objective: To determine the comparison of shrimp shell and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) as tooth remineralization material. Methods: This study was an experimental laboratory with a cross-sectional design. Study sample was 10 maxillary central incisors that were applied with 35% hydrogen peroxide for 2 h, then assessed with energy dispersive spectroscopy (EDS). Samples were divided into 2 groups: 5 samples were applied using CPP-ACP paste and 5 samples using shrimp shell paste every 8 h for 14 consecutive days then checked with EDS. Data analysis using SPSS test independent t-test to compare shrimp shell paste and CPP-ACP paste as tooth remineralization material. Results: The result of this study showed p>0.05, meaning there was no significant difference between CPP-ACP and shrimp shell paste mineral composition. Conclusion: Shrimp shell paste has an effective value to be used as a tooth remineralization material

Research paper thumbnail of The analysis of accelerator concentration effect on setting time and morphology surface impression materials made of brown algae Sargassum sp

Medicina Clínica Práctica, 2020

Objective: To analyze the accelerator concentration on alginate impression material setting time ... more Objective: To analyze the accelerator concentration on alginate impression material setting time made of brown algae Sargassum sp. Method: This study was an experimental laboratory using samples of impression material made of brown algae Sargassum sp. Measurement of setting time using stopwatch and morphological surface analysis using Scanning Electron Magnetic (SEM). Result: The average setting time for the fastest calcium sulfate accelerator is 3.11 min (17 g) and the longest is 6.13 min (15 g). As for the fastest potassium titanium fluoride accelerator material the timeline setting is 3.81 min (4 g) and the longest is 5.73 min (2 g). SEM analysis showed that alginate printing impression materials with accelerator materials of calcium sulfate 17 g and potassium titanium fluoride 4 g showed the smaller, finer denser and more homogenous surface morphology. Conclusion: Impression material made of Sargassum sp. with accelerator calcium sulfate 17 g and potassium titanium fluoride 4 g has a better setting time and surface morphology.

Research paper thumbnail of Compressive and tensile strength measurement of irreversible hydrocolloid impression material made of brown algae Padina sp

Journal of Dentomaxillofacial Science, 2021

Objective: This study aimed to explore the potential of brown algae (Padina sp) by measuring its ... more Objective: This study aimed to explore the potential of brown algae (Padina sp) by measuring its compressive and tensile strength as a preparation step for making standardized dental impression materials from sodium alginate Padina sp. Material and Methods: This study was a quasi-experimental study with one-shot case design. Brown algae were taken from the waters of Punaga and Puntondo, Takalar. Sodium alginate was extracted from algae then mixed with other compositions to form alginate impression material. Compressive and tensile were tested using the Point Load Test. impression material. Compressive and tensile were tested using the Point Load Test. Results: Compressive strength of impression material made of Padina sp was higher than that of standard impression material with pressure mean 0.011 Mpa and 0.009 Mpa. The mean tensile strength measurement was 0.003 Mpa. Conclusion: Mean compressive and tensile strength of impression material made of Padina sp were still relatively weak.

Research paper thumbnail of An Analysis of the Compounds of Dental Enamel after Application Strawberry Gel with Energy-Dispersive X-ray Spectroscopy ( EDS

To analyze compounds of dental enamel after strawberry gel application. This study using six cent... more To analyze compounds of dental enamel after strawberry gel application. This study using six central incisors maxillary that has been extracted. Six central incisors maxillary were divided into five time series, one tooth is used as a control and five tooth given applications of strawberry gel for 1 hour, 1 hour 30 minutes, 2 hours, 2 hours 30 minutes and 3 hours. Then, compounds of dental enamel observed by using Energy-Dispersive X-Ray Spectroscopy. An analysis using nonparametric test (Kruskal Wallis test) to determine differences compounds that occur at each time range. The results of this study, p value = 0.406> 0.05. This means there is no significant difference on dental enamel compound between the control group and the group that had been treated with strawberry gel application. There was no significant effect between time duration and changes in mineral compounds of dental enamel after application of strawberry gel. Clinical article (J Int Dent Med Res 2018; 11(2): pp. 6...

Research paper thumbnail of Differences of Post-Placement Bone Implant Contact (BIC) Value of Dental Implant Coated and Not Coated With Platelet Rich Plasma (PRP)

Global Journal of Health Science, 2017

OBJECTIVE: The success of a dental dental implant treatment focuses on a phenomenon called osseoi... more OBJECTIVE: The success of a dental dental implant treatment focuses on a phenomenon called osseointegration. Evaluation of Bone Area (BA) and Bone-Dental implant Contact (BIC) through histomorphometric analysis is the most widely used parameter to measure osseointegration. The aim of this study was to see post-placement Bone Dental implant Contact (BIC) value of dental implant coated and not coated with PRP. MATERIALS & METHODS: This study was an experimental laboratory conducted at Laboratory of Veterinary Faculty, Hasanuddin University. The sample was baby buck rabbit, aged 4-8 months old, weight 1500–2000 gram, divided into 2 groups each group consist of 12 rabbit, control group not coated with PRP and treatment group coated with PRP. Data analysis using SPSS version 20.0 (SPSS Inc., Chicago, IL, USA). RESULTS: There was a significant difference between the mean BIC values and the 20% increase in BIC values in LP1, LP2 and LP3 between treatment and control group on day 0, 3, 7, a...

Research paper thumbnail of The effectiveness of game-based education on dental and oral health behavior: Systematic review

The skill of brushing teeth has a significant role in preventing dental caries. To improve teeth ... more The skill of brushing teeth has a significant role in preventing dental caries. To improve teeth brushing skills. Health education is needed for children from an early age. Educational media determine the effectiveness of children's learning. So there needs to be treated using android-based educational game media to attract students' attention to learning. Objective: To determine the effectiveness of Game-Based Education on Dental and Oral Health Behavior in Literature Review Results: Of the 11 works of literature reviewed, 7 of them discussed changes in dental and oral health, with 6 showing positive results and one literature showing negative results, but the literature still shows an improvement in oral health, but not significantly. These results can be obtained due to the lack of samples and short observation times. However, 6 of the literature reviewed showed favorable oral health conditions. Conclusion: This paper presents a review of several pieces of literature that highlight the effectiveness of game-based education on oral health behavior. The literature obtained generally shows positive results in increasing knowledge and behavior of oral health.

Research paper thumbnail of Efficacy of Stigma maydis (Corn silk) in Reducing Blood Sugar Level and Subduing Periodontal Inflammation

Systematic Reviews in Pharmacy, 2020

Diabetes is one of the most common non-communicable diseases in the world, according to the World... more Diabetes is one of the most common non-communicable diseases in the world, according to the World Health Organization (WHO). Diabetes is a complex chronic disease with many side complications; one of them is periodontitis or periodontal tissue inflammation. The two are linked to each other by a high blood glucose level. The purpose of this research was to discern the efficacy of Stigma maydis extract as a topical medication to decrease hyperglycemia also subdues periodontal tissue inflammation. Fifteen Male Wistar rats were included in this study, and the periodontitis model was induced using ligatures tied in lower first incisors; also, alloxan was used to create a diabetes mellitus model in the study animals. The result showed that blood sugar level in Fa group was unsteady (p >0.05), and there was an increase in the blood glucose level after a decrease, while both Fb and Fc groups showed stable blood glucose decrease (p<0.05). Fc managed to subdue the inflammation with mild inflammation results (p<0.05), while both Fa & Fb showed less effect with only moderate inflammation (p>0.05). From this study, it can be concluded that topically administered corn silk extract is efficient in reducing blood sugar levels and subduing periodontal tissue inflammation in diabetes-induced albino rats.

Research paper thumbnail of Where Microneedle Meets Biomarkers: Futuristic Application for Diagnosing and Monitoring Localized External Organ Diseases (Adv. Healthcare Mater. 5/2023)

Advanced Healthcare Materials, Feb 1, 2023

Research paper thumbnail of The effectiveness of game-based education on dental and oral health behavior: Systematic review

Open Journal of Clinical and Medical Images

Preliminary: The skill of brushing teeth has a significant role in preventing dental caries. To i... more Preliminary: The skill of brushing teeth has a significant role in preventing dental caries. To improve teeth brushing skills. Health education is needed for children from an early age. Educational media determine the effectiveness of childrens learning. So there needs to be treated using android-based educational game media to attract students attention to learning.

Research paper thumbnail of Where Microneedle Meets Biomarkers: Futuristic Application for Diagnosing and Monitoring Localized External Organ Diseases

Advanced Healthcare Materials

Extracellular tissue fluids are interesting biomatrices that have recently attracted scientists&#... more Extracellular tissue fluids are interesting biomatrices that have recently attracted scientists' interest. Many significant biomarkers for localized external organ diseases have been isolated from this biofluid. In the diagnostic and disease monitoring context, measuring biochemical entities from the fluids surrounding the diseased tissues may give more important clinical value than measuring them at a systemic level. Despite all these facts, pushing tissue fluid‐based diagnosis and monitoring forward to clinical settings faces one major problem: its accessibility. Most extracellular tissue fluid, such as interstitial fluid (ISF), is abundant but hard to collect, and the currently available technologies are invasive and expensive. This is where novel microneedle technology can help tackle this significant obstacle. The ability of microneedle technology to minimally invasively access tissue fluid‐containing biomarkers will enable ISF and other tissue fluid utilization in the clin...

Research paper thumbnail of The Hard Tissue Lesions Associated with Impacted Teeth

Systematic Reviews in Pharmacy, 2020

This Radiography helps a dentist to evaluate the condition of hard tissue in the oral cavity. Rad... more This Radiography helps a dentist to evaluate the condition of hard tissue in the oral cavity. Radiography is one of the tools to establish the diagnosis of impacted teeth and the accompanied hard tissue lesions. Lesions that could accompany impacted teeth not only caries lesions but also lesions that extend into the jaw region. The purpose of this study was to determine the prevalence of impacted teeth accompanied by hard tissue lesions at Dental and Oral Hospital of Hasanuddin University based on panoramic radiography. This research was descriptive observational with consecutive sampling. The study population was all panoramic radiography data of patients aged 21-40 years that viewed from the medical record data from 2016-2017. Data obtained then processed in table form. The result showed that the frequency of impacted occurrence based on its location, 56.2%, occurs in the mandible. Impacted teeth that accompanied by caries was 53.4%, the periapical abscess was 28.8%, and the dentigerous cyst was 17.8%. The conclusion indicated that almost every case of impacted would be accompanied by a hard tissue lesion, either caries lesion or a lesion that extends into the jaw.

Research paper thumbnail of The Effect of Low Bone Mineral Density in Stomatognatic System

Osteoporosis is a systemic bone disease that characterized by low bone mineral density. The study... more Osteoporosis is a systemic bone disease that characterized by low bone mineral density. The study was aimed to determine the relationship between bone mineral density status with the severity of periodontal disease and tooth loss. The study was conducted on patients who come to RSUP.DR.Wahidin Sudiro Husodo with the sample size is 33 people. After completing dental records, each oral cavity of the sampleswas examine of by using a panoramic dental x-ray to see the level of alveolar bone resorption. A complete blood laboratory test was performed to value calcium serum. Examination of bone mineral density conducted at the lumbal spine and the femoral head by using DXA. The results show that low levels of BMD to periodontal status showed a significant result (p = 0.005). The level of bone resorption occured greater in mandible than in maxilla. However, calcium serum levels showed no significant results in the low BMD (p> 0.005). In addition, there were no statistically significant re...

Research paper thumbnail of Efficacy of Stigma maydis (Corn silk) in Reducing Blood Sugar Level and Subduing Periodontal Inflammation

Systematic Reviews in Pharmacy, 2020

Diabetes is one of the most common non-communicable diseases in the world, according to the World... more Diabetes is one of the most common non-communicable diseases in the world, according to the World Health Organization (WHO). Diabetes is a complex chronic disease with many side complications; one of them is periodontitis or periodontal tissue inflammation. The two are linked to each other by a high blood glucose level. The purpose of this research was to discern the efficacy of Stigma maydis extract as a topical medication to decrease hyperglycemia also subdues periodontal tissue inflammation. Fifteen Male Wistar rats were included in this study, and the periodontitis model was induced using ligatures tied in lower first incisors; also, alloxan was used to create a diabetes mellitus model in the study animals. The result showed that blood sugar level in Fa group was unsteady (p >0.05), and there was an increase in the blood glucose level after a decrease, while both Fb and Fc groups showed stable blood glucose decrease (p

Research paper thumbnail of Analysis of first permanent molar condition on Kindergarten student aged 5-6 years old in Eastern Suburban Area of Makassar City

Journal of Dentomaxillofacial Science, 2020

The aim of this study was to analyze the first permanent molar condition on kindergarten student ... more The aim of this study was to analyze the first permanent molar condition on kindergarten student aged 5-6 years old in eastern suburban area of Makassar city. Material and methods: This study was a descriptive observational study on 100 kindergarten students from four schools in Tamalanrea District, Makassar City. Data was collected with clinical examination and interview. Data was gathered in terms of DMFT status of first permanent molar and OHI-S. Data was analyzed with descriptive statistics and t-test. In this descriptive cross-sectional study. Statistical analysis was performed by descriptive statistics and t-test. statistics and t-test. In this descriptive cross-sectional study. Statistical analysis was performed by descriptive statistics and t-test. Results: Mean DMFT of first permanent molars was 1.00 ± 1.10, with a higher value seen among boys. Mean decayed teeth component was 0.95, followed by filled (0.10) and missing (0.0) components. Conclusion: The observed oral hygiene status among the 5-6 yearolds necessitates implementing preventive as well as restorative measures to improve the oral health status of the young population.

Research paper thumbnail of Oral mucosa lesion prevalence at Department of Oral Medicine, Halimah Daeng Sikati dental hospital in Makassar

Journal of Dentomaxillofacial Science, 2016

Objective: To compare the effects of platelet-rich fibrin (PRF) and connective tissue graft (CTG)... more Objective: To compare the effects of platelet-rich fibrin (PRF) and connective tissue graft (CTG) in gingival recession treatment using coronally advanced flap (CAF) Methods: Electronic Pubmed, Wiley, and EMBASE searches were conducted to identify articles published in dental journals without any restrictions of publication date. Gingival Recession Depth (RD), Keratinized Tissue Width (KTW), Probing Depth (PD), Clinical Attachment Level (CAL) and % Complete Root Coverage (CRC) were evaluated at baseline and 6 months. Patients with discomfort postsurgery was measured by comparing Visual Analog Scale (VAS) scores. Manual searches of human clinical trial and related articles were performed afterward. There are 31 studies explained about this, but only 6 studies met the inclusion criteria. Results: The initial database search produced 221 titles. All articles were selected for full-text review. Six studies were selected for inclusion, with 88 patients as subjects. Most of the studies showed the decreased of RD, PD, CAL and the increased of KTW in both techniques at baseline and 6 months follow up. The percentage of CRC showed higher in CTG rather than PRF whereas VAS score showed lower in PRF group Conclusion: Both PRF + CAF and CTG + CAF techniques are effective procedures in the treatment of gingival recession. The combination of CAF+CTG achieved a better result in root coverage however, PRF avoids a donor site, which means a major decrease in postoperative discomfort.

Research paper thumbnail of Saliva parameter analysis on smoker and non smoker patients exposed to intraoral radiography

Objective: To analyze saliva parameter such as salivary pH, total protein, buffer capacity, as we... more Objective: To analyze saliva parameter such as salivary pH, total protein, buffer capacity, as well as sodium and potassium level on smoker and non smoker patients after exposed to intraoral radiography. Material and Methods: This study was an observational study with cross-sectional design. Samples were smoker and non smoker patients who were referred to Dental Hospital Hasanuddin University. Saliva samples were taken by draining method. Samples were transferred immediately to Laboratory of Biochemistry, Faculty of Mathematics and Science to be processed regarding saliva pH, saliva total protein, buffer capacity, as well as saliva sodium and potassium level. Saliva pH were measured with pH meter Hanna instruments, total protein with Lowry’s method, buffer capacity with Ericcson’s method, sodium and potassium level with atomic absorption spectrophotometer Parking Elmer A400. Data were then analyzed with statistical test Kolmogorov Smirnov, independent t-test, and oneway Anova with p...

Research paper thumbnail of An Analysis of Dental Enamel after Bleaching using 35% Hydrogen Peroxide with Energy-dispersive X-ray Spectroscopy

World Journal of Dentistry, 2017

Introduction: Hydrogen peroxide (H 2 O 2) is an effective bleaching agent of tooth whitening, but... more Introduction: Hydrogen peroxide (H 2 O 2) is an effective bleaching agent of tooth whitening, but its use causes changes in the chemical composition of the elements that configure tooth enamel. The purpose of this study is to determine whether there are changes in the composition of the elements that configure the tooth enamel after bleaching using 35% H 2 O 2. Materials and methods: This study was performed in vitro, which is an experimental research laboratory with controlled time series design. The samples used in this study were six permanent incisors postextraction and are divided into treatment and control groups. The control group was soaked in saline and treatment groups applied with H 2 O 2 35%, with time series of 1, 1.5, 2, 2.5, and 3 hours. The elemental composition of enamel was observed using energy-dispersive X-ray spectroscopy analysis; results can be obtained both qualitatively and quantitatively. This study was analyzed using non-parametric test (Kruskal-Wallis test) to determine changes in enamel composition after bleaching, whether there is a change in enamel composition or not. Results: The results of this study showed a p-value of 0.406 (p < 0.05; significant). The result shows a change in the composition of dental enamel after bleaching using 35% H 2 O 2. Conclusion: Application of 35% H 2 O 2 as the bleaching agent does not have a significant influence on changes in the composition of the elements contained in the enamel.

Research paper thumbnail of The analysis of accelerator concentration effect on setting time and morphology surface impression materials made of brown algae Sargassum sp

Medicina clínica práctica, Jun 1, 2020

Objective: To analyze the accelerator concentration on alginate impression material setting time ... more Objective: To analyze the accelerator concentration on alginate impression material setting time made of brown algae Sargassum sp. Method: This study was an experimental laboratory using samples of impression material made of brown algae Sargassum sp. Measurement of setting time using stopwatch and morphological surface analysis using Scanning Electron Magnetic (SEM). Result: The average setting time for the fastest calcium sulfate accelerator is 3.11 min (17 g) and the longest is 6.13 min (15 g). As for the fastest potassium titanium fluoride accelerator material the timeline setting is 3.81 min (4 g) and the longest is 5.73 min (2 g). SEM analysis showed that alginate printing impression materials with accelerator materials of calcium sulfate 17 g and potassium titanium fluoride 4 g showed the smaller, finer denser and more homogenous surface morphology. Conclusion: Impression material made of Sargassum sp. with accelerator calcium sulfate 17 g and potassium titanium fluoride 4 g has a better setting time and surface morphology.

Research paper thumbnail of Comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptide-amorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material

Journal of dentomaxillofacial science, Dec 1, 2018

The aim of this study was to determine the comparison of blood clam (anadara granosa) shell paste... more The aim of this study was to determine the comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptideamorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material. Material and Methods: This study was an experimental laboratory with cross sectional design. Study sample was 15 maxillary central incisors that were applied with 35% hydrogen peroxide for 2 hours, then assessed with Energy Dispersive Spectroscopy (EDS). Samples were divided into 3 groups: 5 samples were applied using blood clam (anadara granosa) shell paste, 5 samples using shrimp shell paste and 5 samples were applied using CPP-ACP paste every 8 hours for 14 consecutive days then checked with EDS. Data analysis using SPSS test independent t-test to see comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptide-amorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material. Results: The result of this study showed P> 0.05 which means there was no significant difference between blood clam shell paste, shrimp shell paste and CPP-ACP mineral composition. Conclusion: Blood clam shell paste and shrimp shell paste has an effective value to be used as tooth remineralization material.

Research paper thumbnail of The Effect of Oral Health Status on Elderly Quality of Life in Makassar District, Indonesia

Systematic Reviews in Pharmacy, 2020

The objective of this study is to determine the effect of oral health status on the quality of li... more The objective of this study is to determine the effect of oral health status on the quality of life of older people living with families in Tamalanrea District, Makassar. This study was an observational analytic study with a cross-sectional design. The study was conducted on 268 elderly samples, dental and oral health status was measured using the OHI-S index and DMF-T. The level of quality of life was measured by GOHAI. The study showed that caries affected the quality of life of the elderly (p = 0.000), oral hygiene affected the quality of life of the elderly (p = 0.001), tooth loss affected the quality of life of the elderly (p = 0.000), and using dentures affected the quality living elderly (p = 0.000). Based on the study conducted, there is an effect of dental and oral health status on the quality of life of elderly living with families in Tamalanrea District, Makassar.

Research paper thumbnail of Comparison of Shrimp (Litopenaeus Vannamei) Shell Paste and Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-Acp) Paste as Teeth Remineralization Material

Objective: To determine the comparison of shrimp shell and casein phosphopeptide-amorphous calciu... more Objective: To determine the comparison of shrimp shell and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) as tooth remineralization material. Methods: This study was an experimental laboratory with a cross-sectional design. Study sample was 10 maxillary central incisors that were applied with 35% hydrogen peroxide for 2 h, then assessed with energy dispersive spectroscopy (EDS). Samples were divided into 2 groups: 5 samples were applied using CPP-ACP paste and 5 samples using shrimp shell paste every 8 h for 14 consecutive days then checked with EDS. Data analysis using SPSS test independent t-test to compare shrimp shell paste and CPP-ACP paste as tooth remineralization material. Results: The result of this study showed p>0.05, meaning there was no significant difference between CPP-ACP and shrimp shell paste mineral composition. Conclusion: Shrimp shell paste has an effective value to be used as a tooth remineralization material

Research paper thumbnail of The analysis of accelerator concentration effect on setting time and morphology surface impression materials made of brown algae Sargassum sp

Medicina Clínica Práctica, 2020

Objective: To analyze the accelerator concentration on alginate impression material setting time ... more Objective: To analyze the accelerator concentration on alginate impression material setting time made of brown algae Sargassum sp. Method: This study was an experimental laboratory using samples of impression material made of brown algae Sargassum sp. Measurement of setting time using stopwatch and morphological surface analysis using Scanning Electron Magnetic (SEM). Result: The average setting time for the fastest calcium sulfate accelerator is 3.11 min (17 g) and the longest is 6.13 min (15 g). As for the fastest potassium titanium fluoride accelerator material the timeline setting is 3.81 min (4 g) and the longest is 5.73 min (2 g). SEM analysis showed that alginate printing impression materials with accelerator materials of calcium sulfate 17 g and potassium titanium fluoride 4 g showed the smaller, finer denser and more homogenous surface morphology. Conclusion: Impression material made of Sargassum sp. with accelerator calcium sulfate 17 g and potassium titanium fluoride 4 g has a better setting time and surface morphology.

Research paper thumbnail of Compressive and tensile strength measurement of irreversible hydrocolloid impression material made of brown algae Padina sp

Journal of Dentomaxillofacial Science, 2021

Objective: This study aimed to explore the potential of brown algae (Padina sp) by measuring its ... more Objective: This study aimed to explore the potential of brown algae (Padina sp) by measuring its compressive and tensile strength as a preparation step for making standardized dental impression materials from sodium alginate Padina sp. Material and Methods: This study was a quasi-experimental study with one-shot case design. Brown algae were taken from the waters of Punaga and Puntondo, Takalar. Sodium alginate was extracted from algae then mixed with other compositions to form alginate impression material. Compressive and tensile were tested using the Point Load Test. impression material. Compressive and tensile were tested using the Point Load Test. Results: Compressive strength of impression material made of Padina sp was higher than that of standard impression material with pressure mean 0.011 Mpa and 0.009 Mpa. The mean tensile strength measurement was 0.003 Mpa. Conclusion: Mean compressive and tensile strength of impression material made of Padina sp were still relatively weak.

Research paper thumbnail of An Analysis of the Compounds of Dental Enamel after Application Strawberry Gel with Energy-Dispersive X-ray Spectroscopy ( EDS

To analyze compounds of dental enamel after strawberry gel application. This study using six cent... more To analyze compounds of dental enamel after strawberry gel application. This study using six central incisors maxillary that has been extracted. Six central incisors maxillary were divided into five time series, one tooth is used as a control and five tooth given applications of strawberry gel for 1 hour, 1 hour 30 minutes, 2 hours, 2 hours 30 minutes and 3 hours. Then, compounds of dental enamel observed by using Energy-Dispersive X-Ray Spectroscopy. An analysis using nonparametric test (Kruskal Wallis test) to determine differences compounds that occur at each time range. The results of this study, p value = 0.406> 0.05. This means there is no significant difference on dental enamel compound between the control group and the group that had been treated with strawberry gel application. There was no significant effect between time duration and changes in mineral compounds of dental enamel after application of strawberry gel. Clinical article (J Int Dent Med Res 2018; 11(2): pp. 6...

Research paper thumbnail of Differences of Post-Placement Bone Implant Contact (BIC) Value of Dental Implant Coated and Not Coated With Platelet Rich Plasma (PRP)

Global Journal of Health Science, 2017

OBJECTIVE: The success of a dental dental implant treatment focuses on a phenomenon called osseoi... more OBJECTIVE: The success of a dental dental implant treatment focuses on a phenomenon called osseointegration. Evaluation of Bone Area (BA) and Bone-Dental implant Contact (BIC) through histomorphometric analysis is the most widely used parameter to measure osseointegration. The aim of this study was to see post-placement Bone Dental implant Contact (BIC) value of dental implant coated and not coated with PRP. MATERIALS & METHODS: This study was an experimental laboratory conducted at Laboratory of Veterinary Faculty, Hasanuddin University. The sample was baby buck rabbit, aged 4-8 months old, weight 1500–2000 gram, divided into 2 groups each group consist of 12 rabbit, control group not coated with PRP and treatment group coated with PRP. Data analysis using SPSS version 20.0 (SPSS Inc., Chicago, IL, USA). RESULTS: There was a significant difference between the mean BIC values and the 20% increase in BIC values in LP1, LP2 and LP3 between treatment and control group on day 0, 3, 7, a...