IJIRMPS International Journal - Academia.edu (original) (raw)

Papers by IJIRMPS International Journal

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2023

Objective: This study assessed the impact of combined motor and cognitive training on balance, fa... more Objective: This study assessed the impact of combined motor and cognitive training on balance, fall risk, and functional mobility in older adults.

Methods: A total of 60 participants aged 65 and older were randomly assigned to one of three groups: combined motor and cognitive training, motor training only, or cognitive training only. Each group underwent their respective training for 60 minutes, three times a week over 12 weeks. Balance was assessed using the Berg Balance Scale (BBS), fall risk was measured by the Timed Up and Go Test (TUG), and functional mobility was evaluated with the Dynamic Gait Index (DGI).

Results: The combined training group demonstrated significant improvements in balance (BBS: baseline 42.5, post-intervention 47.8, p=0.035), reduced fall risk (TUG: baseline 15.3 seconds, post-intervention 12.8 seconds, p=0.042), and enhanced functional mobility (DGI: baseline 18.6, post-intervention 22.3, p=0.029) compared to the motor and cognitive training-only groups. The motor training group showed moderate improvements, while the cognitive training group exhibited minimal changes.

Conclusion: Combined motor and cognitive training effectively improves balance, reduces fall risk, and enhances functional mobility in older adults. This integrated approach offers a more comprehensive strategy for managing balance impairments compared to single-task training.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2022

This study investigates the effectiveness of mirror therapy in managing phantom limb pain (PLP) a... more This study investigates the effectiveness of mirror therapy in managing phantom limb pain (PLP) and enhancing function in amputees. Methods: A randomized controlled trial was conducted with 30 amputees (15 in the mirror therapy group and 15 in the control group). The mirror therapy group received 30-minute sessions of mirror therapy three times per week for 12 weeks, while the control group continued with standard care. Outcomes were measured using the Visual Analogue Scale (VAS) for pain, the McGill Pain Questionnaire (MPQ) for pain quality, and the Jebsen-Taylor Hand Function Test (JTHFT) and Timed Up and Go Test (TUG) for motor function. Results: The mirror therapy group demonstrated significant reductions in PLP, with VAS scores decreasing from 7.6 ±1.2 to 4.0 ±1.1 and MPQ total scores improving from 35.4 ±8.7 to 18.2 ±6.5. Motor function also improved, with JTHFT scores for upper limb amputees improving from 45.2 ±12.3 to 30.5 ±10.2 and TUG scores for lower limb amputees improving from 15.6 ±3.2 to 12.4 ±2.9. The control group showed less improvement in these measures. Conclusion: Mirror therapy is effective in reducing phantom limb pain and improving motor function in amputees. These findings support the integration of mirror therapy into rehabilitation programs for enhanced patient outcomes.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2021

This study evaluates the effectiveness of virtual reality (VR) rehabilitation on motor function a... more This study evaluates the effectiveness of virtual reality (VR) rehabilitation on motor function and quality of life in patients with Parkinson's disease (PD). Methods: A randomized controlled trial was conducted with 20 PD patients, who were assigned to either a VR rehabilitation group (n=10) or a traditional physical therapy control group (n=10). The VR intervention consisted of 30-minute sessions, three times per week for 12 weeks, using a commercially available VR system. Motor function was assessed using the Unified Parkinson's Disease Rating Scale (UPDRS) Part III, and quality of life was measured with the Parkinson's Disease Questionnaire-39 (PDQ-39). Assessments were conducted at baseline, 6 weeks, and 12 weeks. Results: The VR group exhibited significant improvements in UPDRS Part III scores (27.5 ±6.2) compared to the control group (31.5 ±9.0) at 12 weeks (p = 0.03). Additionally, the VR group showed a greater reduction in PDQ-39 total scores (37.8 ±9.5) compared to the control group (43.5 ±12.1) (p = 0.04). Conclusion: VR rehabilitation significantly enhances motor function and quality of life in PD patients compared to traditional physical therapy. The interactive and engaging nature of VR may contribute to improved therapeutic outcomes.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2021

This study investigates the effectiveness of combined nursing and respiratory interventions in pr... more This study investigates the effectiveness of combined nursing and respiratory interventions in preventing hospital-acquired pneumonia (HAP) among critically ill patients. Methods: A quantitative, retrospective cohort design was employed. Data from 200 adult patients admitted to the ICU and general medical wards were analyzed. Patients were divided into two groups: those receiving combined nursing and respiratory interventions (n=100) and those receiving standard care (n=100). The primary outcome was the incidence of HAP, with secondary outcomes including duration of mechanical ventilation, length of ICU and hospital stays, and mortality rates. Results: The incidence of HAP was significantly lower in the combined interventions group (10%) compared to the standard care group (22%) (p=0.03). Although there was a trend towards shorter durations of mechanical ventilation and ICU stays in the combined interventions group, only the length of ICU stay showed statistical significance (p=0.03). Mortality rates were similar between the two groups. Conclusion: Combined nursing and respiratory interventions effectively reduce the incidence of hospitalacquired pneumonia in critically ill patients. While these interventions showed trends towards reduced ICU and hospital stays, no significant differences in mortality rates were observed.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2023

Background: The rise of digital health interventions has prompted an exploration of their effecti... more Background: The rise of digital health interventions has prompted an exploration of their effectiveness in improving medication management. This study evaluates the impact of telepharmacy services, remote counseling, and virtual medication reviews on medication adherence and clinical outcomes.

Methods: A mixed-methods approach was employed, including a quantitative analysis of 300 patients (100 per service type) and qualitative interviews with 30 participants (10 patients and 10 healthcare professionals per service type). Quantitative data encompassed adherence rates, clinical outcomes, and patient satisfaction, while qualitative data were gathered through semi-structured interviews.

Results: Telepharmacy showed the highest adherence rate (85.4%) and patient satisfaction score (4.5), and it led to the most significant improvements in blood pressure and blood glucose levels. Remote counseling and virtual medication reviews also demonstrated benefits but with slightly lower effectiveness. Qualitative analysis revealed high satisfaction with telepharmacy and virtual medication reviews, though technical issues and engagement difficulties were noted as challenges. Participants suggested enhancing technical support and increasing personalization of services.

Conclusion: Telepharmacy, remote counseling, and virtual medication reviews effectively improve medication adherence and clinical outcomes. Telepharmacy, in particular, offers notable advantages in terms of adherence and patient satisfaction. Addressing technical challenges and personalizing care are critical for optimizing these digital health interventions.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2021

Objective: This study aimed to evaluate the impact of medication counselling on treatment adheren... more Objective: This study aimed to evaluate the impact of medication counselling on treatment adherence among oncology patients using a retrospective analysis.
Methods: We conducted a retrospective cohort study involving 150 oncology patients, divided into two groups: those who received medication counselling (n=75) and those who did not (n=75). Data on medication adherence, including Proportion of Days Covered (PDC) and medication refill rates, were extracted from electronic health records. Multivariate regression analysis was used to assess the impact of counselling while controlling for potential confounders.
Results: Patients who received medication counselling had a significantly higher mean PDC (0.85) compared to the non-counseled group (0.77, p=0.04). Medication refill rates were also higher in the counselled group (85.4%) versus the non-counselled group (77.2%, p=0.03). Multivariate analysis confirmed that medication counseling was a significant predictor of higher adherence (p=0.02), independent of other factors such as age, gender, and treatment regimen.
Conclusion: Medication counseling is associated with improved treatment adherence among oncology patients. Integrating structured counseling into oncology care can enhance adherence and potentially improve clinical outcomes.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2020

Background: Effective communication between pharmacists and other healthcare professionals is cru... more Background: Effective communication between pharmacists and other healthcare professionals is crucial for optimizing patient care. This study evaluates the effectiveness of various communication strategies in improving interactions among pharmacists, physicians, and nurses. Methods: A cross-sectional survey was conducted with 150 healthcare professionals from three hospitals. The survey assessed communication practices, the use of communication tools, and the perceived effectiveness of strategies such as structured handoff protocols, standardized documentation, regular team meetings, and EHR integration. Descriptive and inferential statistical analyses were performed. Results: Participants predominantly used EHRs, phone calls, and face-to-face interactions. Regular team meetings received the highest effectiveness ratings, while structured handoff protocols and standardized documentation also scored well. Significant differences were noted in the perception of regular team meetings across roles, with physicians and nurses rating them more favorably than pharmacists. Conclusions: The study highlights the positive impact of communication strategies on healthcare practices, emphasizing the importance of regular team meetings and standardized documentation. Tailoring communication strategies to the roles of different healthcare professionals can enhance overall effectiveness.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2018

This study evaluates the impact of a pharmacist-integrated care model on medication use and clini... more This study evaluates the impact of a pharmacist-integrated care model on medication use and clinical indicators in patients with chronic diseases. Methods: A retrospective analysis was conducted involving 200 patients and utilizing both quantitative and qualitative data. Medication adherence rates and clinical indicators such as blood glucose levels, blood pressure, and LDL cholesterol were analyzed before and after the implementation of the pharmacist-integrated care model. Additionally, semi-structured interviews with 10 healthcare professionals provided qualitative insights into the model's effectiveness and challenges. Results: The study found a significant increase in medication adherence from 65% to 80% (p < 0.01). Improvements in clinical indicators included reductions in blood glucose levels (150 ±20 mg/dL to 130 ±18 mg/dL, p < 0.01), systolic blood pressure (145 ±15 mmHg to 130 ±14 mmHg, p < 0.01), and LDL cholesterol (120 ±25 mg/dL to 100 ±22 mg/dL, p < 0.05). Qualitative data highlighted benefits such as enhanced medication management and improved patient outcomes, while also identifying barriers such as integration challenges and communication gaps. Conclusion: The pharmacist-integrated care model effectively improved medication adherence and clinical outcomes in chronic disease patients. Addressing integration barriers and enhancing collaboration are crucial for optimizing these models in chronic disease management.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2017

This study examines the relationship between medication errors and adverse events, with a focus o... more This study examines the relationship between medication errors and adverse events, with a focus on preventable harm to patients. It aims to identify the prevalence of medication errors, their impact on patient safety, and effective interventions. Methods: A mixed-methods approach was used, including a quantitative analysis of 150 patient medical records and incident reports to quantify medication errors and their associations with adverse events. Qualitative data were gathered through semi-structured interviews with 10 healthcare professionals to explore causes, challenges, and effective strategies for error prevention. Results: The quantitative analysis revealed that "Wrong Dose" errors were significantly associated with severe adverse events. The qualitative findings identified communication breakdowns, complex medication regimens, and inadequate systems as major causes of medication errors. Challenges in error prevention included workload constraints, insufficient training, and technology limitations. Effective interventions included medication reconciliation, enhanced use of Electronic Health Records (EHRs), and improved team communication. Conclusion: Medication errors are prevalent and closely linked to adverse events, with specific error types contributing to more severe outcomes. Addressing communication issues, simplifying medication regimens, and improving systems and processes are crucial for reducing errors. Effective interventions, including medication reconciliation and better team communication, are essential for enhancing medication safety.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2016

Background: Effective medication reconciliation and patient education during hospital discharge a... more Background: Effective medication reconciliation and patient education during hospital discharge are critical for preventing medication errors and improving patient outcomes. Pharmacists play a key role in these processes, but their impact needs further exploration. Objective: This study examines the role of pharmacists in improving medication reconciliation and patient education during hospital discharge. Methods: A mixed-methods approach was used. Quantitatively, data were collected from 150 patients to assess medication discrepancies and understanding of discharge instructions before and after pharmacist-led interventions. Qualitatively, semi-structured interviews were conducted with 10 pharmacists to explore their experiences and perspectives. Results: Pharmacist-led interventions significantly reduced medication discrepancies from 35 to 12 (p < 0.01) and decreased the percentage of patients with discrepancies from 23% to 8% (p < 0.01). Patient understanding of discharge instructions improved from 68% to 85% (p < 0.01). Qualitative findings revealed that pharmacists effectively addressed challenges such as incomplete medication histories and time constraints, and utilized personalized education to enhance patient understanding. Conclusion: Pharmacists significantly improve medication reconciliation and patient education during discharge. Their involvement reduces medication discrepancies and enhances patient comprehension of discharge instructions, contributing to better patient outcomes.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2015

Background: Frontline pharmacists face significant burnout due to high workload and stress. Ident... more Background: Frontline pharmacists face significant burnout due to high workload and stress. Identifying effective interventions is critical for improving their mental health and job satisfaction. Objective: This study explores interventions to mitigate burnout and support mental health among frontline pharmacists. Methods: A mixed-methods approach was used with 50 pharmacists completing a survey and 10 participating in semi-structured interviews. Quantitative data were analyzed using descriptive and inferential statistics, while qualitative data were analyzed through thematic analysis. Results: High levels of emotional exhaustion and depersonalization were reported. Utilization of mental health support interventions was associated with significantly lower burnout scores (p < 0.05). Key themes included the effectiveness of peer support, professional development, and necessary organizational changes. Conclusion: Mental health support interventions, peer support, professional development, and workload adjustments are effective in reducing burnout among pharmacists. Implementing these strategies can enhance pharmacist well-being and patient care.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2023

Background: Type 2 diabetes mellitus (T2DM) is a multifactorial disease influenced by both geneti... more Background: Type 2 diabetes mellitus (T2DM) is a multifactorial disease influenced by both genetic and environmental factors. Understanding the genetic predisposition can aid in identifying individuals at high risk and inform prevention strategies. Objective: This study investigates the associations between specific genetic variants and T2DM risk, examines gene-environment interactions, and evaluates the utility of polygenic risk scores (PRS) in predicting T2DM susceptibility. Methods: A cross-sectional study was conducted with 100 participants, including 50 T2DM patients and 50 healthy controls. Genotyping of selected single nucleotide polymorphisms (SNPs) in TCF7L2, PPARG, and KCNJ11 genes was performed. PRS was calculated, and gene-environment interactions were assessed. Statistical analyses included logistic regression and interaction models. Results: The TCF7L2 variant (rs7903146) showed a strong association with T2DM (OR = 2.45, p = 0.005). The PPARG Pro12Ala variant had a protective effect (OR = 0.52, p = 0.04), and the KCNJ11 E23K variant increased T2DM risk (OR = 1.85, p = 0.04). Higher PRS quartiles were significantly associated with increased T2DM risk (highest vs. lowest quartile: OR = 3.10, p = 0.003). Significant gene-environment interactions were found between TCF7L2 and physical activity (p = 0.02) and between PPARG and diet (p = 0.03). Conclusion: This study underscores the importance of genetic variants in T2DM risk and highlights the potential of integrating genetic information with lifestyle factors for personalized diabetes prevention strategies.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2021

Background: Neck and shoulder pain is prevalent among office workers due to prolonged sitting and... more Background: Neck and shoulder pain is prevalent among office workers due to prolonged sitting and poor posture. Postural training has been suggested as a remedy, but its long-term effectiveness compared to other interventions remains unclear. Objective: This study investigates the long-term effects of postural training on neck and shoulder pain among office workers and compares its outcomes with ergonomic adjustments and no intervention. Methods: A randomized controlled trial was conducted with 150 office workers experiencing chronic neck and shoulder pain. Participants were divided into three groups: postural training, ergonomic adjustments, and control. Interventions lasted 12 weeks, with outcomes assessed at baseline, post-intervention, and at a 6-month follow-up. Primary measures included pain levels (VAS) and functional disability (NDI, SPADI). Secondary measures included postural alignment and quality of life (SF-36). Results: The postural training group showed significant reductions in pain and functional disability compared to the ergonomic adjustments and control groups. Improvements in postural alignment and quality of life were also more notable in the postural training group. Ergonomic adjustments provided moderate benefits, while the control group showed minimal changes. Conclusion: Postural training is an effective long-term intervention for reducing neck and shoulder pain and improving functional outcomes in office workers. The results support integrating postural training into occupational health programs.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2019

This study investigates the efficacy of biomechanical footwear in improving gait parameters, redu... more This study investigates the efficacy of biomechanical footwear in improving gait parameters, reducing pain, and enhancing functional mobility in patients with hip osteoarthritis, compared to standard footwear and no intervention. Methods: A randomized controlled trial was conducted with 120 participants diagnosed with hip osteoarthritis. Participants were randomly assigned to one of three groups: biomechanical footwear, standard footwear, or control. Outcome measures included gait parameters (stride length, gait speed, cadence), pain levels (Visual Analog Scale), functional mobility (Lower Extremity Functional Scale), and quality of life (Short Form Health Survey). Assessments were performed at baseline, post-intervention (8 weeks), and at a 4-week follow-up. Results: The biomechanical footwear group demonstrated significant improvements in stride length, gait speed, cadence, and pain reduction compared to the standard footwear and control groups. Functional mobility and quality of life also improved significantly in the biomechanical footwear group. The standard footwear group showed some improvement, but less pronounced than the biomechanical footwear group. The control group exhibited no significant changes. Conclusion: Biomechanical footwear significantly enhances gait parameters, reduces pain, and improves functional mobility and quality of life in patients with hip osteoarthritis. These findings suggest that biomechanical footwear is a beneficial intervention for managing hip osteoarthritis.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2018

This study aimed to compare the efficacy of aquatic therapy versus land-based exercises in the re... more This study aimed to compare the efficacy of aquatic therapy versus land-based exercises in the rehabilitation of lower extremity musculoskeletal injuries. Methods: A randomized controlled trial was conducted with 150 participants (aged 18-65) assigned to either aquatic therapy, land-based exercises, or a control group. The interventions lasted 8 weeks, with outcomes assessed using the Visual Analog Scale (VAS) for pain, the Lower Extremity Functional Scale (LEFS) for functional mobility, range of motion measurements, and the Short Form Health Survey (SF-36) for quality of life. Data were analyzed using ANCOVA and paired t-tests. Results: Aquatic therapy significantly outperformed land-based exercises and control in reducing pain (VAS: 3.1 vs. 4.2 vs. 5.8) and improving functional mobility (LEFS: 62.5 vs. 55.8 vs. 60.0), range of motion (degrees: 110.5 vs. 103.5 vs. 98.5), and quality of life (SF-36: 75.5 vs. 68.0 vs. 60.0) both post-treatment and at 3-month follow-up. Conclusion: Aquatic therapy is more effective than land-based exercises and standard care in improving pain, mobility, range of motion, and quality of life for patients with lower extremity injuries. These findings support the inclusion of aquatic therapy in rehabilitation programs.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2024

This study aimed to evaluate the effectiveness of Myofascial Release (MFR) therapy in reducing pa... more This study aimed to evaluate the effectiveness of Myofascial Release (MFR) therapy in reducing pain and improving mobility in patients with fibromyalgia and chronic neck pain, comparing it to standard care and placebo treatments. Methods: In a randomized controlled trial, 120 participants were assigned to one of three groups: MFR therapy, standard care, or placebo. Each group received their respective treatments twice weekly for 8 weeks. Primary outcomes included pain intensity, measured by the Visual Analog Scale (VAS), and mobility, assessed using the Neck Disability Index (NDI) for chronic neck pain and the Fibromyalgia Impact Questionnaire (FIQ) for fibromyalgia. Assessments were conducted at baseline, post-treatment, and at 3month follow-up. Results: The MFR therapy group experienced significantly greater reductions in pain and improvements in mobility compared to the standard care and placebo groups (p < 0.001). No significant differences in quality of life or patient satisfaction were observed among the groups. The findings highlight the superior efficacy of MFR therapy over standard and placebo treatments. Conclusion: Myofascial Release therapy is an effective treatment for reducing pain and improving mobility in patients with fibromyalgia and chronic neck pain. It offers a valuable addition to conventional treatment approaches. Further studies are needed to investigate long-term benefits and underlying mechanisms.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2022

Background: Chronic lower back pain (CLBP) is a prevalent condition often managed with manual the... more Background: Chronic lower back pain (CLBP) is a prevalent condition often managed with manual therapy techniques. This study aimed to compare the effectiveness of spinal manipulation, mobilization, and massage therapy on pain relief and functional improvement in CLBP patients.

Methods: A randomized controlled trial was conducted with 135 participants allocated into three groups: spinal manipulation (n=45), mobilization (n=45), and massage therapy (n=45). Pain and function were assessed using the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI), respectively, at baseline, immediately post-treatment, and at 3-month follow-up. Quality of life and patient satisfaction were also evaluated.

Results: All interventions significantly reduced pain and improved function (p < 0.001). Spinal manipulation provided greater pain relief immediately post-treatment and at 3-month follow-up compared to mobilization and massage therapy (p = 0.03 and p = 0.02, respectively). Mobilization resulted in the greatest functional improvement (p = 0.04 and p = 0.03, respectively). Quality of life improvements and patient satisfaction were similar across groups.

Conclusion: Spinal manipulation, mobilization, and massage therapy are all effective in managing CLBP, with spinal manipulation offering superior pain relief and mobilization yielding the most significant functional gains. These findings support the tailored use of manual therapy techniques based on individual patient needs and clinical goals.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2022

Impact of Sleep Apnea Treatment Compliance on Cardiovascular Health Outcomes Objective: To invest... more Impact of Sleep Apnea Treatment Compliance on Cardiovascular Health Outcomes Objective: To investigate the relationship between adherence to Continuous Positive Airway Pressure (CPAP) therapy and improvements in cardiovascular health outcomes in patients with obstructive sleep apnea (OSA). Methods: A cross-sectional study was conducted with 50 OSA patients using CPAP therapy for at least six months. Participants were categorized into low, moderate, and high adherence groups based on average nightly CPAP usage. Cardiovascular outcomes, including systolic and diastolic blood pressure, lipid profile (total cholesterol, LDL, HDL, and triglycerides), and incidence of cardiovascular events, were assessed. Statistical analyses included multiple regression and correlation analysis to evaluate associations between adherence levels and cardiovascular metrics. Results: Higher CPAP adherence was significantly associated with lower systolic and diastolic blood pressure (p < 0.01). Participants with high adherence had significantly lower LDL cholesterol compared to those with low adherence (p = 0.03), while total cholesterol approached significance (p = 0.05). HDL cholesterol and triglycerides did not show significant differences across adherence levels (p = 0.08 and p = 0.07, respectively). The incidence of cardiovascular events was lower in the high adherence group (p = 0.04). Conclusion: Adherence to CPAP therapy is positively associated with improved cardiovascular health outcomes, including lower blood pressure, better lipid profiles, and reduced incidence of cardiovascular events. These findings emphasize the importance of enhancing patient adherence to CPAP therapy to achieve better cardiovascular health in OSA patients.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2020

This study evaluates the impact of structured patient education programs on compliance with home ... more This study evaluates the impact of structured patient education programs on compliance with home oxygen therapy and associated clinical outcomes in patients with chronic respiratory conditions. Methods: A randomized controlled trial was conducted with 50 patients using home oxygen therapy, randomly assigned to an intervention group (n=25) receiving a structured education program or a control group (n=25) receiving standard care. The education program included four one-hour sessions and weekly follow-up calls. Compliance rates, lung function (FEV1 and FVC), health-related quality of life (HRQoL), and hospitalizations were measured at baseline and after 6 months. Results: The intervention group showed significantly higher compliance rates (85.4% vs. 65.2%, p<0.01) and greater improvements in lung function (FEV1: +0.13 L vs. +0.02 L, p=0.03; FVC: +0.18 L vs. +0.01 L, p=0.02) compared to the control group. HRQoL scores improved more in the intervention group (SGRQ:-10.1 vs.-1.2, p<0.01; EQ-5D: +0.09 vs. +0.01, p=0.04). Additionally, the intervention group experienced fewer respiratory-related hospitalizations (0.8 vs. 1.6, p=0.04). Conclusion: Structured patient education programs significantly improve compliance with home oxygen therapy and lead to better clinical outcomes and quality of life for patients. These findings highlight the importance of integrating comprehensive education into the management of home oxygen therapy to enhance patient care.

International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences, 2021

Background: Effective mucociliary clearance is crucial for cystic fibrosis (CF) management. Postu... more Background: Effective mucociliary clearance is crucial for cystic fibrosis (CF) management. Postural drainage techniques are commonly used to enhance this clearance, but their comparative effectiveness remains uncertain. Objective: This study aimed to evaluate and compare the impact of Chest Physiotherapy (CPT), Positive Expiratory Pressure (PEP) Therapy, and High-Frequency Chest Wall Oscillation (HFCWO) on mucociliary clearance and lung function in CF patients. Methods: In a 12-week randomized controlled trial, 30 CF patients were assigned to one of three intervention groups: CPT, PEP, or HFCWO. Outcomes measured included sputum production, lung function (FEV1 and FVC), quality of life (CFQ-R), and frequency of respiratory exacerbations. Data were analyzed using repeated measures ANOVA and other statistical methods. Results: All techniques resulted in improvements in mucociliary clearance and lung function, with no significant differences observed between groups. Quality of life scores and the frequency of respiratory exacerbations were also similar across interventions. Conclusion: CPT, PEP, and HFCWO are effective in improving mucociliary clearance and lung function in CF patients, with no single technique demonstrating superior effectiveness. Personalized treatment approaches based on patient preferences may optimize management.