Imran Butt - Academia.edu (original) (raw)

Papers by Imran Butt

The completion of this thesis would not have been possible without the generous help of many. Fir... more The completion of this thesis would not have been possible without the generous help of many. Firstly, it is an honour to thank my supervisors, Drs. Jonathan Wattis and Giles Richardson. In particular, I am indebted to Jonathan, for more than three years of invaluable supervision. I have benefitted enormously from weekly meetings with him, particularly during the more difficult stages of this project. There is no doubt that his meticulous reading of several early drafts of this thesis has led to a much improved manuscript. I am also grateful for the unflagging support of my immediate and extended family, both here and abroad. Throughout my entire life, my immediate family and my mother in particular have made incalculable sacrifices to allow me the privilege of a prolonged period of study. I would like to thank them for their patience and selflessness. I must also thank my good friends in Derby, Long Eaton, Oxford, Sussex, Nottingham, and beyond, for their constant words of encouragement over the years. It is a pleasure to single out Qamran Yaqoob, who has aided me in more ways than I can possibly acknowledge here. I would like to pay tribute to his general computer wizardry, as exemplified by some of the more intricate diagrams throughout this thesis. Lastly, I would like to thank my wonderful nephews, Mannie and Izzy, for frequent (but always welcome!) distraction. I would also like to acknowledge financial support from the Engineering and Physical Sciences Research Council.

Community eye health / International Centre for Eye Health, 2004

Acta orthopaedica Belgica, 2006

The authors present an case of a thumb metacarpophalangeal joint dislocation which was made compl... more The authors present an case of a thumb metacarpophalangeal joint dislocation which was made complicated by the interposition of the sesamoid bone which required open reduction. The intact volar plate prevented closed reduction. The anatomy and surgical management of this unusual case is described.

Physica D: Nonlinear Phenomena, 2007

The Journal of Arthroplasty, 2010

Transplantation, 2010

INTRODUCTION: Endovascular aneurysm repair (EVAR) is an effective modality of treatment for abdom... more INTRODUCTION: Endovascular aneurysm repair (EVAR) is an effective modality of treatment for abdominal aortic aneurysm (AAA), particularly in patients with renal disease, because of advantages over the standard open procedure, including lower morbidity, shorter operative time and shorter hospital stay. There is paucity of data in the transplant literature on RT after EVAR. A Medline search showed two case reports on renal transplantation (RT) after EVAR, including the one from our institution. In this context, we present the outcomes of our two cases of successful RT following EVAR and discuss intraand post-operative issues pertinent to the subject. METHODS: Case 1: A 54-year-old male with end-stage renal failure secondary to membranous nephropathy, was treated successfully with EVAR for an 5.7 cm diameter AAA using an endovascular bifurcated stent graft, where the distal ends extended to the bifurcation of the common iliac arteries. He underwent a deceased donor RT 2 years after EVAR where renal vessels were anastomosed to the recipient external iliac (EI) vessels. A medial dissection occurred on the grossly atherosclerotic EI artery, which was repaired. The vascular anastomosis time was 60 minutes. Case 2: A 64 year-old male with ESRD of unknown cause underwent DD RT 18 months after undergoing EVAR. He has undergone coronary angioplasty and repair of right popliteal aneurysm 1 year ago. The donor renal artery anastomosed to the left EIA just distal to existing aneurysm of the CIA. The vascular anastomosis time was 37 minutes. RESULTS: Postoperatively, both transplants functioned immediately with progressive fall in the serum creatinine. Duplex and Mag3 scans showed well-perfused kidney with patent EI arteries. No dislodgement, migration, endoleak, dissection or thrombosis of the stent occurred. A follow-up computerised tomographic scan showed minor dissection of the EIA and normal renal allograft vessel in the first case 1 year after RT. CONCLUSIONS: Current evidences show favourable outcomes of EVAR in normal population, in patients with renal diseases and in renal transplant recipients. Although the long-term outcomes of RT after EVAR remain unknown, from the experience of our two successful RTs, we endorse RT in renal failure patients who have undergone EVAR in the past.

The completion of this thesis would not have been possible without the generous help of many. Fir... more The completion of this thesis would not have been possible without the generous help of many. Firstly, it is an honour to thank my supervisors, Drs. Jonathan Wattis and Giles Richardson. In particular, I am indebted to Jonathan, for more than three years of invaluable supervision. I have benefitted enormously from weekly meetings with him, particularly during the more difficult stages of this project. There is no doubt that his meticulous reading of several early drafts of this thesis has led to a much improved manuscript. I am also grateful for the unflagging support of my immediate and extended family, both here and abroad. Throughout my entire life, my immediate family and my mother in particular have made incalculable sacrifices to allow me the privilege of a prolonged period of study. I would like to thank them for their patience and selflessness. I must also thank my good friends in Derby, Long Eaton, Oxford, Sussex, Nottingham, and beyond, for their constant words of encouragement over the years. It is a pleasure to single out Qamran Yaqoob, who has aided me in more ways than I can possibly acknowledge here. I would like to pay tribute to his general computer wizardry, as exemplified by some of the more intricate diagrams throughout this thesis. Lastly, I would like to thank my wonderful nephews, Mannie and Izzy, for frequent (but always welcome!) distraction. I would also like to acknowledge financial support from the Engineering and Physical Sciences Research Council.

Community eye health / International Centre for Eye Health, 2004

Acta orthopaedica Belgica, 2006

The authors present an case of a thumb metacarpophalangeal joint dislocation which was made compl... more The authors present an case of a thumb metacarpophalangeal joint dislocation which was made complicated by the interposition of the sesamoid bone which required open reduction. The intact volar plate prevented closed reduction. The anatomy and surgical management of this unusual case is described.

Physica D: Nonlinear Phenomena, 2007

The Journal of Arthroplasty, 2010

Transplantation, 2010

INTRODUCTION: Endovascular aneurysm repair (EVAR) is an effective modality of treatment for abdom... more INTRODUCTION: Endovascular aneurysm repair (EVAR) is an effective modality of treatment for abdominal aortic aneurysm (AAA), particularly in patients with renal disease, because of advantages over the standard open procedure, including lower morbidity, shorter operative time and shorter hospital stay. There is paucity of data in the transplant literature on RT after EVAR. A Medline search showed two case reports on renal transplantation (RT) after EVAR, including the one from our institution. In this context, we present the outcomes of our two cases of successful RT following EVAR and discuss intraand post-operative issues pertinent to the subject. METHODS: Case 1: A 54-year-old male with end-stage renal failure secondary to membranous nephropathy, was treated successfully with EVAR for an 5.7 cm diameter AAA using an endovascular bifurcated stent graft, where the distal ends extended to the bifurcation of the common iliac arteries. He underwent a deceased donor RT 2 years after EVAR where renal vessels were anastomosed to the recipient external iliac (EI) vessels. A medial dissection occurred on the grossly atherosclerotic EI artery, which was repaired. The vascular anastomosis time was 60 minutes. Case 2: A 64 year-old male with ESRD of unknown cause underwent DD RT 18 months after undergoing EVAR. He has undergone coronary angioplasty and repair of right popliteal aneurysm 1 year ago. The donor renal artery anastomosed to the left EIA just distal to existing aneurysm of the CIA. The vascular anastomosis time was 37 minutes. RESULTS: Postoperatively, both transplants functioned immediately with progressive fall in the serum creatinine. Duplex and Mag3 scans showed well-perfused kidney with patent EI arteries. No dislodgement, migration, endoleak, dissection or thrombosis of the stent occurred. A follow-up computerised tomographic scan showed minor dissection of the EIA and normal renal allograft vessel in the first case 1 year after RT. CONCLUSIONS: Current evidences show favourable outcomes of EVAR in normal population, in patients with renal diseases and in renal transplant recipients. Although the long-term outcomes of RT after EVAR remain unknown, from the experience of our two successful RTs, we endorse RT in renal failure patients who have undergone EVAR in the past.