Jacob Wilensky - Academia.edu (original) (raw)
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Papers by Jacob Wilensky
Ophthalmology, 1995
To study eyes that manifested glaucoma after congenital cataract surgery and to identify factors ... more To study eyes that manifested glaucoma after congenital cataract surgery and to identify factors that might lead to better diagnosis and treatment of such glaucoma. A retrospective review of patients treated for glaucoma that developed after congenital cataract surgery. Sixty-four eyes of 38 patients were studied. Open-angle glaucoma was the more frequent type of glaucoma (51 eyes, 79.7%). Glaucoma was diagnosed a mean interval of 12.2 years after cataract surgery, but it could occur at any time from months to decades after the cataract surgery. Medications alone were successful in intraocular pressure control in 21 (63.6%) of 33 eyes, and additional surgical procedures resulted in successful intraocular pressure control in 11 of 14 eyes in which they were performed. The authors cannot predict in which eyes glaucoma will develop after surgery for congenital cataracts. Once detected, the glaucoma can be treated successfully in the majority of cases. Careful follow-up, including examinations with the patient sedated or anesthetized as needed, is required.
Ophthalmology, 1997
The purpose was to study the long-term outcomes of primary trabeculectomies that were successful ... more The purpose was to study the long-term outcomes of primary trabeculectomies that were successful at 1 year. Design: A retrospective study of patients with various types of glaucoma who had trabeculectomies that were successful at 1 year and who had a follow-up of at least 10 years. Participants: There were 40 patients (40 eyes) who had primary trabeculectomies that were successful at 1 year and who had a follow-up range of 10 to 21 years. Intervention: Control of intraocular pressure (lOP) and disease progression was evaluated at 5, 10, and 15 years and at the last obtainable follow-up. Main Outcome Measures: Successful control of lOP was defined as lOP less than 21 mmHg or a reduction of 33% if preoperative lOP was less than 21 mmHg. Successful control of disease progression was defined as stable cup-disc ratios determined by examination, or color photographs or both, as well as stable visual fields. Results: If an eye was considered successful by lOP at 1 year, the probability of successful control of lOP was 82% at 5 years and 67% at 10 and 15 years. If an eye was considered successful by lOP at 1 year, the probability of successful control of disease progression at 5 years was 77%, at 10 years 61 %, and at 15 years 48%. If an eye did not require further glaucoma surgery at 1 year, the probability that it still would not need further surgery at 5 years was 90%, at 10 years 75%, and at 15 years 67%. Forty percent of eyes had cataract extraction by the time of last follow-up examination. Conclusions: Loss of lOP control and progression of glaucomatous damage occurs over time despite initial success at 1 year.
American Journal of Ophthalmology, 2003
To determine the calculated daily patient cost (cost minimization) of medical glaucoma therapy an... more To determine the calculated daily patient cost (cost minimization) of medical glaucoma therapy and review cost trends. • DESIGN: Experimental, controlled, prospective study. • METHODS: The actual volume of various glaucoma medications or glaucoma medications with redesigned bottles was determined for most commercially available sizes of the tested products. The drops per milliliter based on the actual volume and the daily costs of the dosage schedules recommended by the manufacturers were compared. The cost of each bottle of medication was determined from the average wholesale price (AWP) in the United States. A comparison to 1999 prices where applicable will be analyzed to review costing trends. • RESULTS: The generic timolol products (range, 0.38−0.38-0.38−0.46 per day) were similar on a cost per day basis vs Betimol (Santen,
Ophthalmology, 1995
To study eyes that manifested glaucoma after congenital cataract surgery and to identify factors ... more To study eyes that manifested glaucoma after congenital cataract surgery and to identify factors that might lead to better diagnosis and treatment of such glaucoma. A retrospective review of patients treated for glaucoma that developed after congenital cataract surgery. Sixty-four eyes of 38 patients were studied. Open-angle glaucoma was the more frequent type of glaucoma (51 eyes, 79.7%). Glaucoma was diagnosed a mean interval of 12.2 years after cataract surgery, but it could occur at any time from months to decades after the cataract surgery. Medications alone were successful in intraocular pressure control in 21 (63.6%) of 33 eyes, and additional surgical procedures resulted in successful intraocular pressure control in 11 of 14 eyes in which they were performed. The authors cannot predict in which eyes glaucoma will develop after surgery for congenital cataracts. Once detected, the glaucoma can be treated successfully in the majority of cases. Careful follow-up, including examinations with the patient sedated or anesthetized as needed, is required.
Ophthalmology, 1997
The purpose was to study the long-term outcomes of primary trabeculectomies that were successful ... more The purpose was to study the long-term outcomes of primary trabeculectomies that were successful at 1 year. Design: A retrospective study of patients with various types of glaucoma who had trabeculectomies that were successful at 1 year and who had a follow-up of at least 10 years. Participants: There were 40 patients (40 eyes) who had primary trabeculectomies that were successful at 1 year and who had a follow-up range of 10 to 21 years. Intervention: Control of intraocular pressure (lOP) and disease progression was evaluated at 5, 10, and 15 years and at the last obtainable follow-up. Main Outcome Measures: Successful control of lOP was defined as lOP less than 21 mmHg or a reduction of 33% if preoperative lOP was less than 21 mmHg. Successful control of disease progression was defined as stable cup-disc ratios determined by examination, or color photographs or both, as well as stable visual fields. Results: If an eye was considered successful by lOP at 1 year, the probability of successful control of lOP was 82% at 5 years and 67% at 10 and 15 years. If an eye was considered successful by lOP at 1 year, the probability of successful control of disease progression at 5 years was 77%, at 10 years 61 %, and at 15 years 48%. If an eye did not require further glaucoma surgery at 1 year, the probability that it still would not need further surgery at 5 years was 90%, at 10 years 75%, and at 15 years 67%. Forty percent of eyes had cataract extraction by the time of last follow-up examination. Conclusions: Loss of lOP control and progression of glaucomatous damage occurs over time despite initial success at 1 year.
American Journal of Ophthalmology, 2003
To determine the calculated daily patient cost (cost minimization) of medical glaucoma therapy an... more To determine the calculated daily patient cost (cost minimization) of medical glaucoma therapy and review cost trends. • DESIGN: Experimental, controlled, prospective study. • METHODS: The actual volume of various glaucoma medications or glaucoma medications with redesigned bottles was determined for most commercially available sizes of the tested products. The drops per milliliter based on the actual volume and the daily costs of the dosage schedules recommended by the manufacturers were compared. The cost of each bottle of medication was determined from the average wholesale price (AWP) in the United States. A comparison to 1999 prices where applicable will be analyzed to review costing trends. • RESULTS: The generic timolol products (range, 0.38−0.38-0.38−0.46 per day) were similar on a cost per day basis vs Betimol (Santen,