Jerico Alcantara - Academia.edu (original) (raw)

Jerico Alcantara

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Papers by Jerico Alcantara

Research paper thumbnail of Direct Succinic Acid Production from Minimally Pretreated Biomass Using Sequential Solid-State and Slurry Fermentation with Mixed Fungal Cultures

Fermentation, 2017

Conventional bio-based succinic acid production involves anaerobic bacterial fermentation of pure... more Conventional bio-based succinic acid production involves anaerobic bacterial fermentation of pure sugars. This study explored a new route for directly producing succinic acid from minimally-pretreated lignocellulosic biomass via a consolidated bioprocessing technology employing a mixed lignocellulolytic and acidogenic fungal co-culture. The process involved a solid-state pre-fermentation stage followed by a two-phase slurry fermentation stage. During the solid-state pre-fermentation stage, Aspergillus niger and Trichoderma reesei were co-cultured in a nitrogen-rich substrate (e.g., soybean hull) to induce cellulolytic enzyme activity. The ligninolytic fungus Phanerochaete chrysosporium was grown separately on carbon-rich birch wood chips to induce ligninolytic enzymes, rendering the biomass more susceptible to cellulase attack. The solid-state pre-cultures were then combined in a slurry fermentation culture to achieve simultaneous enzymatic cellulolysis and succinic acid production. This approach generated succinic acid at maximum titers of 32.43 g/L after 72 h of batch slurry fermentation (~10 g/L production), and 61.12 g/L after 36 h of addition of fresh birch wood chips at the onset of the slurry fermentation stage (~26 g/L production). Based on this result, this approach is a promising alternative to current bacterial succinic acid production due to its minimal substrate pretreatment requirements, which could reduce production costs.

Research paper thumbnail of Effect of Acetic Acid on Succinic Acid Production of Fungal Co-culture in Slurry Fermentation

Chemical engineering transactions, 2020

The effect of initial acetic acid concentration on succinic acid production from biologically pre... more The effect of initial acetic acid concentration on succinic acid production from biologically pretreated birchwood chip-soybean hull mixture using co-culture of Aspergillus niger, Phanerochaete chrysosporium, and Trichoderma reesei in a slurry batch fermentation set-up was investigated. Acetic acid was supplied in various initial concentration: 1.65 g/L, 3.75 g/L, and 5.85 g/L. Low initial acetic acid resulted in decline of succinic acid production which coincided with declining acetic acid concentration. On the other hand, both medium and high initial acetic acid sustained higher succinic acid production with nearly constant acetic acid concentration throughout the five-day slurry batch fermentation. The residual sugar concentration was also observed as this was indirectly affected by the presence of acetic acid in the mixture. The presence of acetic acid in the fermentation media plays a crucial role in the production of succinic acid from a non-conventional source, the fungal co-...

Research paper thumbnail of Direct Succinic Acid Production from Minimally Pretreated Biomass Using Sequential Solid-State and Slurry Fermentation with Mixed Fungal Cultures

Fermentation, 2017

Conventional bio-based succinic acid production involves anaerobic bacterial fermentation of pure... more Conventional bio-based succinic acid production involves anaerobic bacterial fermentation of pure sugars. This study explored a new route for directly producing succinic acid from minimally-pretreated lignocellulosic biomass via a consolidated bioprocessing technology employing a mixed lignocellulolytic and acidogenic fungal co-culture. The process involved a solid-state pre-fermentation stage followed by a two-phase slurry fermentation stage. During the solid-state pre-fermentation stage, Aspergillus niger and Trichoderma reesei were co-cultured in a nitrogen-rich substrate (e.g., soybean hull) to induce cellulolytic enzyme activity. The ligninolytic fungus Phanerochaete chrysosporium was grown separately on carbon-rich birch wood chips to induce ligninolytic enzymes, rendering the biomass more susceptible to cellulase attack. The solid-state pre-cultures were then combined in a slurry fermentation culture to achieve simultaneous enzymatic cellulolysis and succinic acid production. This approach generated succinic acid at maximum titers of 32.43 g/L after 72 h of batch slurry fermentation (~10 g/L production), and 61.12 g/L after 36 h of addition of fresh birch wood chips at the onset of the slurry fermentation stage (~26 g/L production). Based on this result, this approach is a promising alternative to current bacterial succinic acid production due to its minimal substrate pretreatment requirements, which could reduce production costs.

Research paper thumbnail of Effect of Acetic Acid on Succinic Acid Production of Fungal Co-culture in Slurry Fermentation

Chemical engineering transactions, 2020

The effect of initial acetic acid concentration on succinic acid production from biologically pre... more The effect of initial acetic acid concentration on succinic acid production from biologically pretreated birchwood chip-soybean hull mixture using co-culture of Aspergillus niger, Phanerochaete chrysosporium, and Trichoderma reesei in a slurry batch fermentation set-up was investigated. Acetic acid was supplied in various initial concentration: 1.65 g/L, 3.75 g/L, and 5.85 g/L. Low initial acetic acid resulted in decline of succinic acid production which coincided with declining acetic acid concentration. On the other hand, both medium and high initial acetic acid sustained higher succinic acid production with nearly constant acetic acid concentration throughout the five-day slurry batch fermentation. The residual sugar concentration was also observed as this was indirectly affected by the presence of acetic acid in the mixture. The presence of acetic acid in the fermentation media plays a crucial role in the production of succinic acid from a non-conventional source, the fungal co-...

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