Jorge Balteiro - Academia.edu (original) (raw)
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Faculdade de Medicina da Universidade do Porto
UFMG - The Federal University of Minas Gerais
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Papers by Jorge Balteiro
Revista Portuguesa de Saude Publica, 2011
Crohn's Disease (CD) is an intestinal chronic inflammatory disease included in the group of infla... more Crohn's Disease (CD) is an intestinal chronic inflammatory disease included in the group of inflammatory bowel disease. It is associated with an inflammatory process and may affect any part of the gastrointestinal tract. The pathogenesis of CD has become better understood owing to advances in genetic and immunologic technology. Studies suggest that the origin of the inflammation may be due to an exacerbated response of the immune system. The elevated production of inflammatory cytokines, such as tumor necrosis factor-alpha, in CD patients were described. The new therapeutic with biological agents were developed for CD patients who not respond to conventional therapy. These novel biologics has been shown frequently to decrease the inflammatory activity in the gut, with the goal to achieve remission with mucosal healing. The Infliximab therapy is one of more used in these patients. However, there are many patients who do not respond or lose response. Who do not respond to these therapeutics have other biologic therapeutics such as Certolizumab Pegol, Natalizumab, Vedolizumab, Ustekinumab and Secukinumab. It is necessary to analyse the effectiveness and safety of these treatments to see which is most effective.
European Journal of Public Health
Background Cutaneous melanoma is an aggressive cancer that occurs in melanocytes, located in the ... more Background Cutaneous melanoma is an aggressive cancer that occurs in melanocytes, located in the epidermis. Historically it has a high rate of morbidity and mortality, due to the resistance and toxicity of traditional therapies. Its incidence has increased annually by 4% to 8%. Until 2011 it was still considered a devastating and almost always fatal disease in a few months. Advances in therapies have significantly improved the results of most patients with advanced melanoma, especially those with a BRAFV600 mutation, which account for almost 50% of tumors. Before the recent evolution in treatment, the prognosis and overall survival were considered very bad. The introduction of new drugs has improved progression-free survival and overall survival, as well as producing faster clinical responses. Methods Comparison of endpoints such as progression-free survival and overall melanoma survival from the Summary of Product Characteristics (SPC) studies of each drug in the therapeutic groups...
European Journal of Public Health
Background Nowadays there has been a greater concern for health and well-being, as well as the co... more Background Nowadays there has been a greater concern for health and well-being, as well as the constant search for the ‘ideal body’ trend. As a consequence, vitamin, protein and food supplements are more and more frequent in the population's dietary pattern, as compensation for an unbalanced diet and in the fight against intense physical/psychological wear and tear. The main objective of the study was to assess the prevalence of consumption of nutritional supplements by gym goers. Methods This is an observational, descriptive and cross-sectional study, lasting 9 months and with the collection of information through a questionnaire. The statistical treatment of the data was carried out with the aid of the SPSS program. Results It was found that the prevalence of consumption is higher in males (58.9%). The most consumed type of vitamin supplement were multivitamins with mineral salts (46.2%) and whey protein (89%) as a protein supplement. The most cited reason for its consumption ...
Revista Portuguesa de Saude Publica, 2011
Crohn's Disease (CD) is an intestinal chronic inflammatory disease included in the group of infla... more Crohn's Disease (CD) is an intestinal chronic inflammatory disease included in the group of inflammatory bowel disease. It is associated with an inflammatory process and may affect any part of the gastrointestinal tract. The pathogenesis of CD has become better understood owing to advances in genetic and immunologic technology. Studies suggest that the origin of the inflammation may be due to an exacerbated response of the immune system. The elevated production of inflammatory cytokines, such as tumor necrosis factor-alpha, in CD patients were described. The new therapeutic with biological agents were developed for CD patients who not respond to conventional therapy. These novel biologics has been shown frequently to decrease the inflammatory activity in the gut, with the goal to achieve remission with mucosal healing. The Infliximab therapy is one of more used in these patients. However, there are many patients who do not respond or lose response. Who do not respond to these therapeutics have other biologic therapeutics such as Certolizumab Pegol, Natalizumab, Vedolizumab, Ustekinumab and Secukinumab. It is necessary to analyse the effectiveness and safety of these treatments to see which is most effective.
European Journal of Public Health
Background Cutaneous melanoma is an aggressive cancer that occurs in melanocytes, located in the ... more Background Cutaneous melanoma is an aggressive cancer that occurs in melanocytes, located in the epidermis. Historically it has a high rate of morbidity and mortality, due to the resistance and toxicity of traditional therapies. Its incidence has increased annually by 4% to 8%. Until 2011 it was still considered a devastating and almost always fatal disease in a few months. Advances in therapies have significantly improved the results of most patients with advanced melanoma, especially those with a BRAFV600 mutation, which account for almost 50% of tumors. Before the recent evolution in treatment, the prognosis and overall survival were considered very bad. The introduction of new drugs has improved progression-free survival and overall survival, as well as producing faster clinical responses. Methods Comparison of endpoints such as progression-free survival and overall melanoma survival from the Summary of Product Characteristics (SPC) studies of each drug in the therapeutic groups...
European Journal of Public Health
Background Nowadays there has been a greater concern for health and well-being, as well as the co... more Background Nowadays there has been a greater concern for health and well-being, as well as the constant search for the ‘ideal body’ trend. As a consequence, vitamin, protein and food supplements are more and more frequent in the population's dietary pattern, as compensation for an unbalanced diet and in the fight against intense physical/psychological wear and tear. The main objective of the study was to assess the prevalence of consumption of nutritional supplements by gym goers. Methods This is an observational, descriptive and cross-sectional study, lasting 9 months and with the collection of information through a questionnaire. The statistical treatment of the data was carried out with the aid of the SPSS program. Results It was found that the prevalence of consumption is higher in males (58.9%). The most consumed type of vitamin supplement were multivitamins with mineral salts (46.2%) and whey protein (89%) as a protein supplement. The most cited reason for its consumption ...