K. Kreutter - Academia.edu (original) (raw)
Papers by K. Kreutter
The Journal of Physical Chemistry, 1994
... A. Jefferson,td J. M. NicovichJ and PH Wine'*t*l*l Georgia Tech Research Institu... more ... A. Jefferson,td J. M. NicovichJ and PH Wine'*t*l*l Georgia Tech Research Institute, School of Chemistry and Biochemistry, and School of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332 Received: November 2, 1993" ... Jefferson et al. 4 L ...
The Journal of Physical Chemistry, 1991
CD3, C2H5, t-C4H9) or C12/RH (R= CH3, C2HS) has been employed to study the kinetics of the reacti... more CD3, C2H5, t-C4H9) or C12/RH (R= CH3, C2HS) has been employed to study the kinetics of the reactions CH3+ HBr (I), CD3+ HBr (2), CH3+ DBr (3), C2H5+ HBr (4), C2H5+ DBr (9, t-C4Hg+ HBr (6), and t-C4H9+ DBr (7) as a function of temperature (257-430 K) and ...
The Journal of Physical Chemistry, 1991
The Journal of Chemical Physics, 1991
International Journal of Chemical Kinetics, 1990
A laser flash photolysis-resonance fluorescence technique has been employed to study the kinetics... more A laser flash photolysis-resonance fluorescence technique has been employed to study the kinetics of the important stratospheric reactions Cl('P,) + O 3 C10 + O2 and Br('P,,,) + O3 -+ BrO + O2 as a function of temperature, The temperature dependence observed for the Cl('P,) + O3 reaction is nonArrhenius, but can be adequately described by the following two Arrhenius expressions (units are cm3 molecule-' s-', errors are 217 and represent precision only): k l ( T ) = (1.19 2 0.21) x lo-" exp [(-33 2 37)/T] for T = 189-269K and k,(T) = (2.49 2 0.38) x lo-'' exp[(-233 f 4 6 ) / n for T = 269-385 K. At temperatures below 230 K, the rate coefficients determined in this study are faster than any reported previously. Incorporation of our values for k,(T) into stratospheric models would increase calculated C10 levels and decrease calculated HCI levels; hence the calculated efficiency of C10, catalyzed ozone destruction would increase. The temperature dependence observed for the Br('P3 ') + O3 reaction is adequately described by the following Arrhenius expression (units are cm3 molecule-' s-', errors are 2 a and represent precision only): k,(n = (1.50 2 0.16) x 10.'' exp[(-775 * 30)/T] for T = 195-392 K. While not in quantitative agreement with Arrhenius parameters reported in most previous studies, our results almost exactly reproduce the average of all earlier studies and, therefore, will not affect the choice of k,(T) for use in modeling stratospheric BrO, chemistry.
Chemical Physics Letters, 1991
Bioorganic & Medicinal Chemistry Letters, 2008
2-Cyano-6-fluorophenylacetamide was explored as a novel P2 scaffold in the design of thrombin inh... more 2-Cyano-6-fluorophenylacetamide was explored as a novel P2 scaffold in the design of thrombin inhibitors. Optimization around this structural motif culminated in 14, which is a potent thrombin inhibitor (K i = 1.2 nM) that exhibits robust efficacy in canine anticoagulation and thrombosis models upon oral administration.
The Journal of Physical Chemistry, 1994
... A. Jefferson,td J. M. NicovichJ and PH Wine'*t*l*l Georgia Tech Research Institu... more ... A. Jefferson,td J. M. NicovichJ and PH Wine'*t*l*l Georgia Tech Research Institute, School of Chemistry and Biochemistry, and School of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332 Received: November 2, 1993" ... Jefferson et al. 4 L ...
The Journal of Physical Chemistry, 1991
CD3, C2H5, t-C4H9) or C12/RH (R= CH3, C2HS) has been employed to study the kinetics of the reacti... more CD3, C2H5, t-C4H9) or C12/RH (R= CH3, C2HS) has been employed to study the kinetics of the reactions CH3+ HBr (I), CD3+ HBr (2), CH3+ DBr (3), C2H5+ HBr (4), C2H5+ DBr (9, t-C4Hg+ HBr (6), and t-C4H9+ DBr (7) as a function of temperature (257-430 K) and ...
The Journal of Physical Chemistry, 1991
The Journal of Chemical Physics, 1991
International Journal of Chemical Kinetics, 1990
A laser flash photolysis-resonance fluorescence technique has been employed to study the kinetics... more A laser flash photolysis-resonance fluorescence technique has been employed to study the kinetics of the important stratospheric reactions Cl('P,) + O 3 C10 + O2 and Br('P,,,) + O3 -+ BrO + O2 as a function of temperature, The temperature dependence observed for the Cl('P,) + O3 reaction is nonArrhenius, but can be adequately described by the following two Arrhenius expressions (units are cm3 molecule-' s-', errors are 217 and represent precision only): k l ( T ) = (1.19 2 0.21) x lo-" exp [(-33 2 37)/T] for T = 189-269K and k,(T) = (2.49 2 0.38) x lo-'' exp[(-233 f 4 6 ) / n for T = 269-385 K. At temperatures below 230 K, the rate coefficients determined in this study are faster than any reported previously. Incorporation of our values for k,(T) into stratospheric models would increase calculated C10 levels and decrease calculated HCI levels; hence the calculated efficiency of C10, catalyzed ozone destruction would increase. The temperature dependence observed for the Br('P3 ') + O3 reaction is adequately described by the following Arrhenius expression (units are cm3 molecule-' s-', errors are 2 a and represent precision only): k,(n = (1.50 2 0.16) x 10.'' exp[(-775 * 30)/T] for T = 195-392 K. While not in quantitative agreement with Arrhenius parameters reported in most previous studies, our results almost exactly reproduce the average of all earlier studies and, therefore, will not affect the choice of k,(T) for use in modeling stratospheric BrO, chemistry.
Chemical Physics Letters, 1991
Bioorganic & Medicinal Chemistry Letters, 2008
2-Cyano-6-fluorophenylacetamide was explored as a novel P2 scaffold in the design of thrombin inh... more 2-Cyano-6-fluorophenylacetamide was explored as a novel P2 scaffold in the design of thrombin inhibitors. Optimization around this structural motif culminated in 14, which is a potent thrombin inhibitor (K i = 1.2 nM) that exhibits robust efficacy in canine anticoagulation and thrombosis models upon oral administration.