Kurt Moody - Academia.edu (original) (raw)

Papers by Kurt Moody

Research paper thumbnail of Clinical performance of the Optima toric contact lens versus the CSI toric contact lens

PubMed, 1997

Purpose: To compare the clinical performance of the Optima soft toric contact lens versus the CSI... more Purpose: To compare the clinical performance of the Optima soft toric contact lens versus the CSI soft toric contact lens. Methods: Twenty-one patients (five affected by allergies) were followed at 2-week intervals for 4 months in a prospective, randomized, double-masked study comparing the Optima soft toric contact lens to the CSI soft toric contact lens. Results: The patients preference evaluation revealed a statistically significant preference for the CIS toric lens in 14 of 16 variables including overall lens preference (P = 0.0001). The two remaining variables, lens awareness (P = 0.07) and foreign body sensation (P = 0.06), showed a trend toward a preference for the CSI toric lens. The less sensitive symptom ranking questionnaire revealed a significance for, or a trend toward, a significant difference in three of 10 variables, all in favor of the CSI toric lens. The mean degrees of axis rotation were 3.5* for the CSI lens and 7.6* for the Optima lens (P = 0.0001). Factor analysis identified a clustering of variables around specific ranked factors. Factors related to 1) allergy status (.93); 2) visual function (.87); 3) ocular surface (.82); and 4) refractive characteristics (.71) were most significant in determining the overall clinical performance of these toric lenses. Allergic patients significantly preferred the CSI toric lens for 15 of 16 variables, whereas non-allergic patients preferred the CSI lens for seven of 16 variables. Conclusions: The patient preference, symptom ranking, and axis rotation analysis of this study revealed a superior performance by the CSI toric contact lens when compared to the Optima toric contact lens. Allergic patients revealed an even stronger and statistically significant preference for the CSI lens when compared to non-allergic patients.

Research paper thumbnail of The annular tinted contact lens syndrome: corneal topographic analysis of ring-shaped irregular astigmatism caused by annular tinted contact lenses

PubMed, Jul 1, 1997

Purpose: Irregular corneal astigmatism has been reported in association with annular tinted hydro... more Purpose: Irregular corneal astigmatism has been reported in association with annular tinted hydrogel contact lenses. We report the abnormal videokeratographic findings of five patients wearing annular tinted contact lenses, who presented with bilateral blurred vision and revealed a loss of best corrected visual acuity. Methods/results: The corneal topographic analysis revealed a previously unreported distinct ring-shaped pattern of irregular astigmatism. The topographic circular band of irregular astigmatism was further characterized by concentric areas of relative steepening, flattening, and steepening with a diameter of approximately 4 mm. This pattern suggests that forces acting at the junctional zone between the tinted area and the clear pupillary area are inducing structural abnormalities of the corneal surface. At the time of presentation, the mean surface regularity index (SRI) was 2.06 (range: 0.61-5.88). The topography and best-corrected visual acuity returned to normal within days of discontinuing annular tinted lens use, and the mean SRI decreased to 0.44 (range: 0.21-1.16). Digital imaging of lenses obtained from our patients and of identical control lenses was performed. A masked analysis suggested that the study lenses contain greater amounts of pigment compared to the control lenses. Conclusions: We present ten characteristic signs and symptoms of this condition, which we have named "the annular tinted contact lens syndrome." Corneal topographic analysis is a powerful tool for detecting specific reversible irregularities of the corneal surface associated with the use of annular tinted contact lenses.

Research paper thumbnail of CLs for presbyopes: Reuseable multifocal

Optician

David Ruston, Greg Williby and Kurt Moody introduce the newly launched Acuvue Oasys Multifocal co... more David Ruston, Greg Williby and Kurt Moody introduce the newly launched Acuvue Oasys Multifocal contact lens

Research paper thumbnail of Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8): Use of an 8-Item Habitual Symptom Score to Reflect Change in Overall Opinion on Contact Lens Performance

Investigative Ophthalmology & Visual Science, 2009

Research paper thumbnail of Addressing common myths and misconceptions in soft contact lens practice

Clinical and Experimental Optometry, 2021

Advances in contact lens technology over the past 50 years since the commercialisation of the fir... more Advances in contact lens technology over the past 50 years since the commercialisation of the first soft lenses in 1971 have been incredible, with significant changes in contact lens materials, frequency of replacement, care systems and lens designs occurring. However, despite the widespread availability of contact lenses, penetration rates for those who need vision correction remain in the low single digits and many practitioners seem to hold on to concepts around the potential value of contact lenses that appear based in the dim and distant past and are certainly no longer valid today. This review addresses 10 common 'myths and misconceptions' around soft contact lenses using an evidence-based approach that can hopefully dispel some of these incorrect assumptions.

Research paper thumbnail of Real World Through Focus Curve of a New Multifocal Contact Lens

Investigative Ophthalmology & Visual Science, 2016

Purpose : The Through Focus Curve (TFC) is often used to characterise visual performance of multi... more Purpose : The Through Focus Curve (TFC) is often used to characterise visual performance of multifocal contact lenses (MCL) and intra ocular lenses over a range of defocus. Typically negative lenses are used to produce vergences but this requires accurate lens centration and trial lenses may interfere with binocularity. The objective was to characterize a new MCL using a new clinical test paradigm, measuring visual acuity (VA) at the actual distances of interest, allowing normal convergence and both binocular and monocular measurements. Methods : Monocular, binocular (B) and binocular summation (BS) TFCs were obtained by measuring logMAR VA at 6 distances (40cm, 50cm, 67cm, 1m, 2m & 4m) for 3 luminances (250cd/m2 daytime and computer use, 50cd/m2 indoor evening & 2.5cd/m2 night driving). The measurements were made with OTG-i Vision using a 4K screen at distance, an iPad 2 Air (retina) for intermediate and an iPad mini (retina) for near, all driven by a dedicated App. The study MCL w...

Research paper thumbnail of The Effect of Age and Refractive Error on Pupil Size

Investigative Ophthalmology & Visual Science, 2015

Purpose: The size of the pupil plays a critical part in controlling the performance of all vision... more Purpose: The size of the pupil plays a critical part in controlling the performance of all vision correction modalities incorporating a presbyopic correction, including contact lenses, refractive surgery and intraocular lenses. While the effect of luminance, the dominant factor affecting pupil size, is well known, little information is available regarding other contributing factors such as aging and refractive status. Methods: Three hundred and four patients (127 Male, 177 Female) aged 18 to 78 year made up the cohort population in this study. The non-interventional investigation involved a single visit to the OTG-i clinic. The pupil size was measured at three controlled luminance levels 250cd/m2 (daytime), 50cd/m2 (indoor lighting) and 2.5cd/m2 (night driving). Results: The results obtained showed that: (i) Pupil size decreases with age, the effect being most marked at low luminance. At 250cd/m2 means: 18-39 yrs = 2.8mm, 40-54 yrs = 2.67mm, 55+yrs = 2.56mm (p=0.046). At 50cd/m2 mea...

Research paper thumbnail of Whether to fit a silicone hydrogel daily disposable lens or a conventional hydrogel daily disposable is a common dilemma in everyday practice

he transition to silicone hydrogels (SiH) from hydrogel contact lenses has been relatively fast i... more he transition to silicone hydrogels (SiH) from hydrogel contact lenses has been relatively fast in recent years such that more than half of all soft lenses prescribed worldwide are now

Research paper thumbnail of Application of RMS Fit Error for Assessing Pre-lens Tear Film Break-up

Research paper thumbnail of Real Time Analysis of Optical Quality and Visual Performance During Tear Breakup

Research paper thumbnail of Evaluation of the visual performance of a new multifocal contact lens and the impact of refractive error

Contact Lens and Anterior Eye, 2018

buy (buyability) was yes/no response. Objective performance measures included high and low-contra... more buy (buyability) was yes/no response. Objective performance measures included high and low-contrast visual acuity (HCVA, LCVA) and contrast sensitivity at 6 m, HCVA at 70 cm, 50 cm and 40 cm. Success was defined as overall-vision satisfaction ≥8 and positive-buyability. Analyses were performed using Chi-square and t-test on the grouped data and further subgroup analyses on lens types. Results: When compared to the successful participants, the unsuccessful ones differed the most for near, followed by intermediate and then distance vision. This was true for both objective and subjective variables (p < 0.001). Success was higher with lowadd, followed by med and high-adds (44%, 22%, 18% respectively, p < 0.05). However, EDOF achieved 2× and 1.5× greater success compared to commercial lenses in the med-high and low-add respectively (p < 0.05). Habitual CL wearers were more successful compared to non-habitual (56% vs. 22%, p < 0.001). Habitual wearers were also more likely to be successful in EDOF compared to AOMF (87% vs. 33%, p = 0.008). Conclusions: Subjective measures were more predictive of success with short-term MFCL wear. Objective near measures (≤70 cm) were also predictive of success compared to distance measures. EDOF improves the success rate even in lower performing presbyopic subgroups .

Research paper thumbnail of The effects of age and refraction on pupil size and visual acuity: Implications for multifocal contact lens design and fitting

Contact Lens and Anterior Eye, 2018

All forms of presbyopic vision correction entail some compromise in either depth of focus, field ... more All forms of presbyopic vision correction entail some compromise in either depth of focus, field of view, binocular vision or image quality. Multifocal contact lenses with aspheric surfaces alter local power resulting in formation of simultaneous images. Aspheric optics increase depth of focus but induce aberrations and alter image quality. The relationship between induced aberrations and visual performance was compared between centre-distance and centre-near multifocal lenses and a single vision lens. Method: Single vision, centre-near and centre-distance lenses with +2.50 nominal add in Comfilcon material were worn in sequence by 10 participants following cycloplegia. Aberrations were measured with the COAS aberrometer with lens on-eye and for bare eye and scaled to a 6 mm pupil. Mean spherical aberration (Z4,0) for the bare eye was +0.17 m. High contrast visual acuity (VA) at 3 m and 40 cm was measured with an ETDRS chart scored on a letter by letter basis. The change in vision at distance and near compared to the single vision control lens was calculated. Results: Centre-near design induced a negative shift in Z4,0 of −0.27 m and centre-distance a positive shift of +0.24 m. Oneye Z4,0 was significantly different between lens types (p < 0.001). Compared to the single vision lens, VA for near dropped 0.11 log-MAR for centre-near and 0.24 logMAR for the centre-distance lens. Vision reduction at near was significantly correlated to the RMS of horizontal and vertical coma (r = 0.827; p = 0.03). At 3 m vision was reduced by 0.28 logMAR for centre-near and 0.18 logMAR for the centre-distance lenses but there was no significant relationship between distance vision drop and either spherical aberration or coma. Conclusions: Individual variation in vision with multifocal CLs can be explained in part by resultant on-eye aberrations. Although all lens fits appeared clinically acceptable, decentration of inherent spherical aberration in the lens designs can induce coma which related to poorer visual performance.

Research paper thumbnail of Visual acuity performance across different near ADD powers with a new multifocal daily disposable lens

Contact Lens and Anterior Eye, 2018

buy (buyability) was yes/no response. Objective performance measures included high and low-contra... more buy (buyability) was yes/no response. Objective performance measures included high and low-contrast visual acuity (HCVA, LCVA) and contrast sensitivity at 6 m, HCVA at 70 cm, 50 cm and 40 cm. Success was defined as overall-vision satisfaction ≥8 and positive-buyability. Analyses were performed using Chi-square and t-test on the grouped data and further subgroup analyses on lens types. Results: When compared to the successful participants, the unsuccessful ones differed the most for near, followed by intermediate and then distance vision. This was true for both objective and subjective variables (p < 0.001). Success was higher with lowadd, followed by med and high-adds (44%, 22%, 18% respectively, p < 0.05). However, EDOF achieved 2× and 1.5× greater success compared to commercial lenses in the med-high and low-add respectively (p < 0.05). Habitual CL wearers were more successful compared to non-habitual (56% vs. 22%, p < 0.001). Habitual wearers were also more likely to be successful in EDOF compared to AOMF (87% vs. 33%, p = 0.008). Conclusions: Subjective measures were more predictive of success with short-term MFCL wear. Objective near measures (≤70 cm) were also predictive of success compared to distance measures. EDOF improves the success rate even in lower performing presbyopic subgroups .

Research paper thumbnail of Visual performance of silicone hydrogel daily disposable contact lenses

Contact Lens and Anterior Eye, 2018

To analyze the variation in vertical coma and the rest of ocular aberrations before and after fit... more To analyze the variation in vertical coma and the rest of ocular aberrations before and after fitting prismatic soft contact lenses (PSCL). Method: Thirty-seven eyes of 20 healthy subjects (24.30 ± 2.03 years) were evaluated in order to analyze the variation in ocular wavefront aberrations before and after fitting PSCL of different base-down prism values (1.0, 1.5 and 2.0 PD), designed to study its influence in the compensation of vertical coma aberration. A Hartmann-Shack sensor with a wavelength of 780 nm was used, considering a pupil size of 3 mm. Additionally, the influence of PSCL in visual function under photopic conditions in terms of highcontrast visual acuity and contrast sensitivity was evaluated. Results: There were statistically significant differences (p < 0.05) in ocular aberrations from 1st to 7th order after fitting PSCL, but only the differences in vertical tilt, horizontal tilt, defocus, vertical astigmatism and vertical coma were clinically relevant (Strehl Ratio < 0.8). The mean of vertical coma (m) was 0.

Research paper thumbnail of Rendimiento clínico de una lente de contacto diaria desechable de hidrogel de silicona

Gaceta Optica Organo Oficial Del Colegio Nacional De Opticos Optometristas De Espana, 2010

Research paper thumbnail of Visual performance with a daily disposable contact lens compared to best corrected sphero-cylindrical spectacle refraction

Contact Lens and Anterior Eye, 2018

More than 4 in 10 contact lens (CL) considerers say application and removal is a potential barrie... more More than 4 in 10 contact lens (CL) considerers say application and removal is a potential barrier to wear, and the principal reason for dropout in the first year with spherical lenses is handling difficulties. A study was conducted to assess the time needed for application and removal in neophytes (NW) and habitual (HW) wearers. Method: NW and HW aged 18-45 years were recruited. HW had a single study visit where they applied and removed a hydrogel daily disposable (DD) lens while being recorded by an iPad application. NW first had a training visit where they watched training videos and then had 1:1 training with a staff member, like that done in practice. If successful (applying and removing the training lenses twice), they returned for a second visit to apply and remove the DD CL while being recorded. Overall time of the video, and technique, was used for the analysis; a cutoff time (10 min) was applied. Subjective questionnaires were completed on handling aspects. Results: A total of 59 subjects completed the study; 30 HW and 29 NW. Mean age was 30.2 ± 6.46 years; 52.5% were female. There were statistically significant differences (p < 0.05) for median time to apply and remove CLs; 20.5 s (range 7-108) versus 101.5 s (range 32-614) to apply and 8.0 s (range 3-21) versus 14.0 s (range 4-116) to remove for HW and NW respectively. Conclusion: The differences in the time to apply and remove CLs between wearer groups, and a wide range of abilities across both groups, highlights the potential difficulties experienced by some NW with handling CLs, and the timing challenge in practice as they become comfortable with application and removal. These findings support the need for continued follow-up and support on applying and removing CLs for NW.

Research paper thumbnail of CLEAR - Effect of contact lens materials and designs on the anatomy and physiology of the eye

Contact Lens and Anterior Eye

Research paper thumbnail of Development of a mass cytometry protocol to assess the inflammatory status of the ocular surface

Contact Lens and Anterior Eye

Research paper thumbnail of Method of improving lens rotation

Research paper thumbnail of Objective Assessment of Ocular Surface Response to Contact Lens Wear in Presbyopic Contact Lens Wearers of Asian Descent

Eye & contact lens, Jan 13, 2016

Contact lens wearers of Asian descent may be predisposed to experience microtrauma of the ocular ... more Contact lens wearers of Asian descent may be predisposed to experience microtrauma of the ocular surface as a result a thinner post-lens tear film and higher eyelid tension, and these effects would be anticipated to be most marked in an older population. The objective of this study was to quantify the mechanical effects of the study contact lenses on the ocular surface in a population of presbyopic contact lens wearers of Asian descent. Twenty established presbyopic contact lens wearers (hydrogel n=5, none habitual wearers of etafilcon A lenses; silicone hydrogel n=15) of Asian descent were refitted with etafilcon A multifocal daily disposable contact lenses (1-DAY ACUVUE MOIST MULTIFOCAL) for a period of 1 month of daily lens wear. The habitual modalities of wear were 45% daily disposable and 55% planned replacement. Digital photographs of the upper lid margins, nasal and temporal conjunctiva, and superior cornea were taken after 6 hr of wear of the participants' habitual conta...

Research paper thumbnail of Clinical performance of the Optima toric contact lens versus the CSI toric contact lens

PubMed, 1997

Purpose: To compare the clinical performance of the Optima soft toric contact lens versus the CSI... more Purpose: To compare the clinical performance of the Optima soft toric contact lens versus the CSI soft toric contact lens. Methods: Twenty-one patients (five affected by allergies) were followed at 2-week intervals for 4 months in a prospective, randomized, double-masked study comparing the Optima soft toric contact lens to the CSI soft toric contact lens. Results: The patients preference evaluation revealed a statistically significant preference for the CIS toric lens in 14 of 16 variables including overall lens preference (P = 0.0001). The two remaining variables, lens awareness (P = 0.07) and foreign body sensation (P = 0.06), showed a trend toward a preference for the CSI toric lens. The less sensitive symptom ranking questionnaire revealed a significance for, or a trend toward, a significant difference in three of 10 variables, all in favor of the CSI toric lens. The mean degrees of axis rotation were 3.5* for the CSI lens and 7.6* for the Optima lens (P = 0.0001). Factor analysis identified a clustering of variables around specific ranked factors. Factors related to 1) allergy status (.93); 2) visual function (.87); 3) ocular surface (.82); and 4) refractive characteristics (.71) were most significant in determining the overall clinical performance of these toric lenses. Allergic patients significantly preferred the CSI toric lens for 15 of 16 variables, whereas non-allergic patients preferred the CSI lens for seven of 16 variables. Conclusions: The patient preference, symptom ranking, and axis rotation analysis of this study revealed a superior performance by the CSI toric contact lens when compared to the Optima toric contact lens. Allergic patients revealed an even stronger and statistically significant preference for the CSI lens when compared to non-allergic patients.

Research paper thumbnail of The annular tinted contact lens syndrome: corneal topographic analysis of ring-shaped irregular astigmatism caused by annular tinted contact lenses

PubMed, Jul 1, 1997

Purpose: Irregular corneal astigmatism has been reported in association with annular tinted hydro... more Purpose: Irregular corneal astigmatism has been reported in association with annular tinted hydrogel contact lenses. We report the abnormal videokeratographic findings of five patients wearing annular tinted contact lenses, who presented with bilateral blurred vision and revealed a loss of best corrected visual acuity. Methods/results: The corneal topographic analysis revealed a previously unreported distinct ring-shaped pattern of irregular astigmatism. The topographic circular band of irregular astigmatism was further characterized by concentric areas of relative steepening, flattening, and steepening with a diameter of approximately 4 mm. This pattern suggests that forces acting at the junctional zone between the tinted area and the clear pupillary area are inducing structural abnormalities of the corneal surface. At the time of presentation, the mean surface regularity index (SRI) was 2.06 (range: 0.61-5.88). The topography and best-corrected visual acuity returned to normal within days of discontinuing annular tinted lens use, and the mean SRI decreased to 0.44 (range: 0.21-1.16). Digital imaging of lenses obtained from our patients and of identical control lenses was performed. A masked analysis suggested that the study lenses contain greater amounts of pigment compared to the control lenses. Conclusions: We present ten characteristic signs and symptoms of this condition, which we have named "the annular tinted contact lens syndrome." Corneal topographic analysis is a powerful tool for detecting specific reversible irregularities of the corneal surface associated with the use of annular tinted contact lenses.

Research paper thumbnail of CLs for presbyopes: Reuseable multifocal

Optician

David Ruston, Greg Williby and Kurt Moody introduce the newly launched Acuvue Oasys Multifocal co... more David Ruston, Greg Williby and Kurt Moody introduce the newly launched Acuvue Oasys Multifocal contact lens

Research paper thumbnail of Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8): Use of an 8-Item Habitual Symptom Score to Reflect Change in Overall Opinion on Contact Lens Performance

Investigative Ophthalmology & Visual Science, 2009

Research paper thumbnail of Addressing common myths and misconceptions in soft contact lens practice

Clinical and Experimental Optometry, 2021

Advances in contact lens technology over the past 50 years since the commercialisation of the fir... more Advances in contact lens technology over the past 50 years since the commercialisation of the first soft lenses in 1971 have been incredible, with significant changes in contact lens materials, frequency of replacement, care systems and lens designs occurring. However, despite the widespread availability of contact lenses, penetration rates for those who need vision correction remain in the low single digits and many practitioners seem to hold on to concepts around the potential value of contact lenses that appear based in the dim and distant past and are certainly no longer valid today. This review addresses 10 common 'myths and misconceptions' around soft contact lenses using an evidence-based approach that can hopefully dispel some of these incorrect assumptions.

Research paper thumbnail of Real World Through Focus Curve of a New Multifocal Contact Lens

Investigative Ophthalmology & Visual Science, 2016

Purpose : The Through Focus Curve (TFC) is often used to characterise visual performance of multi... more Purpose : The Through Focus Curve (TFC) is often used to characterise visual performance of multifocal contact lenses (MCL) and intra ocular lenses over a range of defocus. Typically negative lenses are used to produce vergences but this requires accurate lens centration and trial lenses may interfere with binocularity. The objective was to characterize a new MCL using a new clinical test paradigm, measuring visual acuity (VA) at the actual distances of interest, allowing normal convergence and both binocular and monocular measurements. Methods : Monocular, binocular (B) and binocular summation (BS) TFCs were obtained by measuring logMAR VA at 6 distances (40cm, 50cm, 67cm, 1m, 2m & 4m) for 3 luminances (250cd/m2 daytime and computer use, 50cd/m2 indoor evening & 2.5cd/m2 night driving). The measurements were made with OTG-i Vision using a 4K screen at distance, an iPad 2 Air (retina) for intermediate and an iPad mini (retina) for near, all driven by a dedicated App. The study MCL w...

Research paper thumbnail of The Effect of Age and Refractive Error on Pupil Size

Investigative Ophthalmology & Visual Science, 2015

Purpose: The size of the pupil plays a critical part in controlling the performance of all vision... more Purpose: The size of the pupil plays a critical part in controlling the performance of all vision correction modalities incorporating a presbyopic correction, including contact lenses, refractive surgery and intraocular lenses. While the effect of luminance, the dominant factor affecting pupil size, is well known, little information is available regarding other contributing factors such as aging and refractive status. Methods: Three hundred and four patients (127 Male, 177 Female) aged 18 to 78 year made up the cohort population in this study. The non-interventional investigation involved a single visit to the OTG-i clinic. The pupil size was measured at three controlled luminance levels 250cd/m2 (daytime), 50cd/m2 (indoor lighting) and 2.5cd/m2 (night driving). Results: The results obtained showed that: (i) Pupil size decreases with age, the effect being most marked at low luminance. At 250cd/m2 means: 18-39 yrs = 2.8mm, 40-54 yrs = 2.67mm, 55+yrs = 2.56mm (p=0.046). At 50cd/m2 mea...

Research paper thumbnail of Whether to fit a silicone hydrogel daily disposable lens or a conventional hydrogel daily disposable is a common dilemma in everyday practice

he transition to silicone hydrogels (SiH) from hydrogel contact lenses has been relatively fast i... more he transition to silicone hydrogels (SiH) from hydrogel contact lenses has been relatively fast in recent years such that more than half of all soft lenses prescribed worldwide are now

Research paper thumbnail of Application of RMS Fit Error for Assessing Pre-lens Tear Film Break-up

Research paper thumbnail of Real Time Analysis of Optical Quality and Visual Performance During Tear Breakup

Research paper thumbnail of Evaluation of the visual performance of a new multifocal contact lens and the impact of refractive error

Contact Lens and Anterior Eye, 2018

buy (buyability) was yes/no response. Objective performance measures included high and low-contra... more buy (buyability) was yes/no response. Objective performance measures included high and low-contrast visual acuity (HCVA, LCVA) and contrast sensitivity at 6 m, HCVA at 70 cm, 50 cm and 40 cm. Success was defined as overall-vision satisfaction ≥8 and positive-buyability. Analyses were performed using Chi-square and t-test on the grouped data and further subgroup analyses on lens types. Results: When compared to the successful participants, the unsuccessful ones differed the most for near, followed by intermediate and then distance vision. This was true for both objective and subjective variables (p < 0.001). Success was higher with lowadd, followed by med and high-adds (44%, 22%, 18% respectively, p < 0.05). However, EDOF achieved 2× and 1.5× greater success compared to commercial lenses in the med-high and low-add respectively (p < 0.05). Habitual CL wearers were more successful compared to non-habitual (56% vs. 22%, p < 0.001). Habitual wearers were also more likely to be successful in EDOF compared to AOMF (87% vs. 33%, p = 0.008). Conclusions: Subjective measures were more predictive of success with short-term MFCL wear. Objective near measures (≤70 cm) were also predictive of success compared to distance measures. EDOF improves the success rate even in lower performing presbyopic subgroups .

Research paper thumbnail of The effects of age and refraction on pupil size and visual acuity: Implications for multifocal contact lens design and fitting

Contact Lens and Anterior Eye, 2018

All forms of presbyopic vision correction entail some compromise in either depth of focus, field ... more All forms of presbyopic vision correction entail some compromise in either depth of focus, field of view, binocular vision or image quality. Multifocal contact lenses with aspheric surfaces alter local power resulting in formation of simultaneous images. Aspheric optics increase depth of focus but induce aberrations and alter image quality. The relationship between induced aberrations and visual performance was compared between centre-distance and centre-near multifocal lenses and a single vision lens. Method: Single vision, centre-near and centre-distance lenses with +2.50 nominal add in Comfilcon material were worn in sequence by 10 participants following cycloplegia. Aberrations were measured with the COAS aberrometer with lens on-eye and for bare eye and scaled to a 6 mm pupil. Mean spherical aberration (Z4,0) for the bare eye was +0.17 m. High contrast visual acuity (VA) at 3 m and 40 cm was measured with an ETDRS chart scored on a letter by letter basis. The change in vision at distance and near compared to the single vision control lens was calculated. Results: Centre-near design induced a negative shift in Z4,0 of −0.27 m and centre-distance a positive shift of +0.24 m. Oneye Z4,0 was significantly different between lens types (p < 0.001). Compared to the single vision lens, VA for near dropped 0.11 log-MAR for centre-near and 0.24 logMAR for the centre-distance lens. Vision reduction at near was significantly correlated to the RMS of horizontal and vertical coma (r = 0.827; p = 0.03). At 3 m vision was reduced by 0.28 logMAR for centre-near and 0.18 logMAR for the centre-distance lenses but there was no significant relationship between distance vision drop and either spherical aberration or coma. Conclusions: Individual variation in vision with multifocal CLs can be explained in part by resultant on-eye aberrations. Although all lens fits appeared clinically acceptable, decentration of inherent spherical aberration in the lens designs can induce coma which related to poorer visual performance.

Research paper thumbnail of Visual acuity performance across different near ADD powers with a new multifocal daily disposable lens

Contact Lens and Anterior Eye, 2018

buy (buyability) was yes/no response. Objective performance measures included high and low-contra... more buy (buyability) was yes/no response. Objective performance measures included high and low-contrast visual acuity (HCVA, LCVA) and contrast sensitivity at 6 m, HCVA at 70 cm, 50 cm and 40 cm. Success was defined as overall-vision satisfaction ≥8 and positive-buyability. Analyses were performed using Chi-square and t-test on the grouped data and further subgroup analyses on lens types. Results: When compared to the successful participants, the unsuccessful ones differed the most for near, followed by intermediate and then distance vision. This was true for both objective and subjective variables (p < 0.001). Success was higher with lowadd, followed by med and high-adds (44%, 22%, 18% respectively, p < 0.05). However, EDOF achieved 2× and 1.5× greater success compared to commercial lenses in the med-high and low-add respectively (p < 0.05). Habitual CL wearers were more successful compared to non-habitual (56% vs. 22%, p < 0.001). Habitual wearers were also more likely to be successful in EDOF compared to AOMF (87% vs. 33%, p = 0.008). Conclusions: Subjective measures were more predictive of success with short-term MFCL wear. Objective near measures (≤70 cm) were also predictive of success compared to distance measures. EDOF improves the success rate even in lower performing presbyopic subgroups .

Research paper thumbnail of Visual performance of silicone hydrogel daily disposable contact lenses

Contact Lens and Anterior Eye, 2018

To analyze the variation in vertical coma and the rest of ocular aberrations before and after fit... more To analyze the variation in vertical coma and the rest of ocular aberrations before and after fitting prismatic soft contact lenses (PSCL). Method: Thirty-seven eyes of 20 healthy subjects (24.30 ± 2.03 years) were evaluated in order to analyze the variation in ocular wavefront aberrations before and after fitting PSCL of different base-down prism values (1.0, 1.5 and 2.0 PD), designed to study its influence in the compensation of vertical coma aberration. A Hartmann-Shack sensor with a wavelength of 780 nm was used, considering a pupil size of 3 mm. Additionally, the influence of PSCL in visual function under photopic conditions in terms of highcontrast visual acuity and contrast sensitivity was evaluated. Results: There were statistically significant differences (p < 0.05) in ocular aberrations from 1st to 7th order after fitting PSCL, but only the differences in vertical tilt, horizontal tilt, defocus, vertical astigmatism and vertical coma were clinically relevant (Strehl Ratio < 0.8). The mean of vertical coma (m) was 0.

Research paper thumbnail of Rendimiento clínico de una lente de contacto diaria desechable de hidrogel de silicona

Gaceta Optica Organo Oficial Del Colegio Nacional De Opticos Optometristas De Espana, 2010

Research paper thumbnail of Visual performance with a daily disposable contact lens compared to best corrected sphero-cylindrical spectacle refraction

Contact Lens and Anterior Eye, 2018

More than 4 in 10 contact lens (CL) considerers say application and removal is a potential barrie... more More than 4 in 10 contact lens (CL) considerers say application and removal is a potential barrier to wear, and the principal reason for dropout in the first year with spherical lenses is handling difficulties. A study was conducted to assess the time needed for application and removal in neophytes (NW) and habitual (HW) wearers. Method: NW and HW aged 18-45 years were recruited. HW had a single study visit where they applied and removed a hydrogel daily disposable (DD) lens while being recorded by an iPad application. NW first had a training visit where they watched training videos and then had 1:1 training with a staff member, like that done in practice. If successful (applying and removing the training lenses twice), they returned for a second visit to apply and remove the DD CL while being recorded. Overall time of the video, and technique, was used for the analysis; a cutoff time (10 min) was applied. Subjective questionnaires were completed on handling aspects. Results: A total of 59 subjects completed the study; 30 HW and 29 NW. Mean age was 30.2 ± 6.46 years; 52.5% were female. There were statistically significant differences (p < 0.05) for median time to apply and remove CLs; 20.5 s (range 7-108) versus 101.5 s (range 32-614) to apply and 8.0 s (range 3-21) versus 14.0 s (range 4-116) to remove for HW and NW respectively. Conclusion: The differences in the time to apply and remove CLs between wearer groups, and a wide range of abilities across both groups, highlights the potential difficulties experienced by some NW with handling CLs, and the timing challenge in practice as they become comfortable with application and removal. These findings support the need for continued follow-up and support on applying and removing CLs for NW.

Research paper thumbnail of CLEAR - Effect of contact lens materials and designs on the anatomy and physiology of the eye

Contact Lens and Anterior Eye

Research paper thumbnail of Development of a mass cytometry protocol to assess the inflammatory status of the ocular surface

Contact Lens and Anterior Eye

Research paper thumbnail of Method of improving lens rotation

Research paper thumbnail of Objective Assessment of Ocular Surface Response to Contact Lens Wear in Presbyopic Contact Lens Wearers of Asian Descent

Eye & contact lens, Jan 13, 2016

Contact lens wearers of Asian descent may be predisposed to experience microtrauma of the ocular ... more Contact lens wearers of Asian descent may be predisposed to experience microtrauma of the ocular surface as a result a thinner post-lens tear film and higher eyelid tension, and these effects would be anticipated to be most marked in an older population. The objective of this study was to quantify the mechanical effects of the study contact lenses on the ocular surface in a population of presbyopic contact lens wearers of Asian descent. Twenty established presbyopic contact lens wearers (hydrogel n=5, none habitual wearers of etafilcon A lenses; silicone hydrogel n=15) of Asian descent were refitted with etafilcon A multifocal daily disposable contact lenses (1-DAY ACUVUE MOIST MULTIFOCAL) for a period of 1 month of daily lens wear. The habitual modalities of wear were 45% daily disposable and 55% planned replacement. Digital photographs of the upper lid margins, nasal and temporal conjunctiva, and superior cornea were taken after 6 hr of wear of the participants' habitual conta...