Lineu Fonseca - Academia.edu (original) (raw)

Papers by Lineu Fonseca

Dementia Neuropsychologia, 2010

Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms,... more Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms, but with frequent neuropsychological alterations. Objectives: To study the relationship between clinical and cognitive aspects and the perception of quality of life (QOL) in PD patients. Methods: Twenty consecutive patients (13 men) with idiopathic PD (mean age: 64.5y), mean disease time of 7.8 years and at stages 1-3 according to the modified Hoehn and Yahr staging scale (HYS), all outpatients from the Neurology Department of the Celso Pierro General and Maternity Hospital (PUC-Campinas), were analyzed. The following were applied: a clinical-neurological assessment, the Mini-Mental State Examination (MMSE), standard neuropsychological battery of the CERAD (Consortium to Establish a Registry for Alzheimer's Disease), Hamilton Depression Rating Scale (HAM-D) and a QOL questionnaire (Parkinson's Disease Questionnaire -PDQ-39). Statistical analysis was carried out at a significance level of p<0.05. Results: On the PDQ-39 under the sections total, mobility and activities of daily living, and the items motor compromise (HYS) and language of the MMSE were predictors of worse QOL. Verbal fluency was a factor for emotional well-being on the PDQ-39, whereas higher scores for HAM-D and worse performance on the item attention and calculation of the MMSE were associated with worse QOL in the social support section. Total score on the MMSE and educational level were QOL factors in cognition . Conclusions: The findings of the present study suggest that clinical, cognitive, motor or other depression-related factors contribute differently to the domains of QOL.

Dementia Neuropsychologia, 2010

Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms,... more Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms, but with frequent neuropsychological alterations. Objectives: To study the relationship between clinical and cognitive aspects and the perception of quality of life (QOL) in PD patients. Methods: Twenty consecutive patients (13 men) with idiopathic PD (mean age: 64.5y), mean disease time of 7.8 years and at stages 1-3 according to the modified Hoehn and Yahr staging scale (HYS), all outpatients from the Neurology Department of the Celso Pierro General and Maternity Hospital (PUC-Campinas), were analyzed. The following were applied: a clinical-neurological assessment, the Mini-Mental State Examination (MMSE), standard neuropsychological battery of the CERAD (Consortium to Establish a Registry for Alzheimer's Disease), Hamilton Depression Rating Scale (HAM-D) and a QOL questionnaire (Parkinson's Disease Questionnaire -PDQ-39). Statistical analysis was carried out at a significance level of p<0.05. Results: On the PDQ-39 under the sections total, mobility and activities of daily living, and the items motor compromise (HYS) and language of the MMSE were predictors of worse QOL. Verbal fluency was a factor for emotional well-being on the PDQ-39, whereas higher scores for HAM-D and worse performance on the item attention and calculation of the MMSE were associated with worse QOL in the social support section. Total score on the MMSE and educational level were QOL factors in cognition . Conclusions: The findings of the present study suggest that clinical, cognitive, motor or other depression-related factors contribute differently to the domains of QOL.

Avaliacao Psicologica, Jun 1, 2005

Fatal error: XSL transformation failed. in /home/scielo/www/htdocs/ class.XSLTransformerPHP5.php ... more Fatal error: XSL transformation failed. in /home/scielo/www/htdocs/ class.XSLTransformerPHP5.php on line 40

Avaliacao Psicologica, Jun 1, 2005

Fatal error: XSL transformation failed. in /home/scielo/www/htdocs/ class.XSLTransformerPHP5.php ... more Fatal error: XSL transformation failed. in /home/scielo/www/htdocs/ class.XSLTransformerPHP5.php on line 40

Journal of Epilepsy and Clinical Neurophysiology, 2007

ABSTRACT Epileptic seizures and olanzapine use: two cases report Introduction: Slowing and epilep... more ABSTRACT Epileptic seizures and olanzapine use: two cases report Introduction: Slowing and epileptiform activity in EEG-patterns as well as epileptic seizures have been published during antipsychotic therapy with phenothiazines and butyrophenones. More recently, olanzepine, a new class of antipsychotic drug for use in treatment of refractory schizophrenics has been associated with a low risk of epileptic seizure occurrence. Methods: We studied two patients, 45 and 37 years old, with schizophrenia and generalized epileptic seizures appearing, respectively, four and one month after starting olanzapine treatment. Their electroencephalogram showed spike-wave discharges generalized in one case and focal in the second patient. Conclusion: It was observed an association between epileptic seizures and olanzapine use.

Journal of Epilepsy and Clinical Neurophysiology, 2007

ABSTRACT Epileptic seizures and olanzapine use: two cases report Introduction: Slowing and epilep... more ABSTRACT Epileptic seizures and olanzapine use: two cases report Introduction: Slowing and epileptiform activity in EEG-patterns as well as epileptic seizures have been published during antipsychotic therapy with phenothiazines and butyrophenones. More recently, olanzepine, a new class of antipsychotic drug for use in treatment of refractory schizophrenics has been associated with a low risk of epileptic seizure occurrence. Methods: We studied two patients, 45 and 37 years old, with schizophrenia and generalized epileptic seizures appearing, respectively, four and one month after starting olanzapine treatment. Their electroencephalogram showed spike-wave discharges generalized in one case and focal in the second patient. Conclusion: It was observed an association between epileptic seizures and olanzapine use.

Rev Cienc Med, Jun 1, 2005

Rev Cienc Med, Jun 1, 2005

Revista De Ciencias Medicas, Nov 22, 2012

A avaliação da discriminação entre palavras e pseudopalavras tem sido utilizada para melhor compr... more A avaliação da discriminação entre palavras e pseudopalavras tem sido utilizada para melhor compreensão do processo de leitura e escrita.

Revista De Ciencias Medicas, Nov 22, 2012

A avaliação da discriminação entre palavras e pseudopalavras tem sido utilizada para melhor compr... more A avaliação da discriminação entre palavras e pseudopalavras tem sido utilizada para melhor compreensão do processo de leitura e escrita.

Revista De Ciencias Medicas, Dec 3, 2012

Revista De Ciencias Medicas, Dec 3, 2012

Dement Neuropsychol, Jun 1, 2010

Dement Neuropsychol, Jun 1, 2010

Arquivos De Neuro Psiquiatria, Sep 1, 2007

Arquivos De Neuro Psiquiatria, Sep 1, 2007

Clinical Eeg and Neuroscience Official Journal of the Eeg and Clinical Neuroscience Society, Jul 1, 2009

The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes... more The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes and cognitive disturbance (mild cognitive impairment or dementia) and the motor disturbance stage in Parkinson&#39;s disease (PD). Thirty-two PD patients (age = 67.2 +/- 10.0) and 26 normal subjects (age = 68.4 +/- 4.7) were assessed using a neurological evaluation, modified Hoehn and Yahr (HY) scale for PD, a Portuguese version of the CERAD neuropsychological battery (consortium to establish a registry for Alzheimer&#39;s disease) incorporating the Mini-mental Status Examination, Clinical Dementia Rating and an EEG analysis of absolute and relative band amplitude at rest. Four groups were compared: three with PD (7 patients with dementia, 10 with mild cognitive impairment and 15 with no cognitive disturbances) and the control group. The qEEG showed no significant differences between the control group and PD patients without cognitive disturbance. Abnormalities on the qEEG were essentially associated with the occurrence of mild cognitive impairment or dementia in patients with PD. There was an increase in the absolute and relative posterior theta amplitude in the groups with mild cognitive impairment or dementia and of the posterior absolute and relative delta amplitude in the group with dementia This study suggested qEEG as a possible physiological tool in the assessment of cognitive aspects in PD.

Clinical Eeg and Neuroscience Official Journal of the Eeg and Clinical Neuroscience Society, Jul 1, 2009

The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes... more The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes and cognitive disturbance (mild cognitive impairment or dementia) and the motor disturbance stage in Parkinson&#39;s disease (PD). Thirty-two PD patients (age = 67.2 +/- 10.0) and 26 normal subjects (age = 68.4 +/- 4.7) were assessed using a neurological evaluation, modified Hoehn and Yahr (HY) scale for PD, a Portuguese version of the CERAD neuropsychological battery (consortium to establish a registry for Alzheimer&#39;s disease) incorporating the Mini-mental Status Examination, Clinical Dementia Rating and an EEG analysis of absolute and relative band amplitude at rest. Four groups were compared: three with PD (7 patients with dementia, 10 with mild cognitive impairment and 15 with no cognitive disturbances) and the control group. The qEEG showed no significant differences between the control group and PD patients without cognitive disturbance. Abnormalities on the qEEG were essentially associated with the occurrence of mild cognitive impairment or dementia in patients with PD. There was an increase in the absolute and relative posterior theta amplitude in the groups with mild cognitive impairment or dementia and of the posterior absolute and relative delta amplitude in the group with dementia This study suggested qEEG as a possible physiological tool in the assessment of cognitive aspects in PD.

Avaliacao Psicologica, Jun 1, 2005

... Josiane Maria de Freitas Tonelotto 1 ; Lineu Corrêa Fonseca I ; Glória MSA Tedrus II ; Samant... more ... Josiane Maria de Freitas Tonelotto 1 ; Lineu Corrêa Fonseca I ; Glória MSA Tedrus II ; Samanta Maria Visigalli Martins III ; Maria Agnes ... Capovilla, Capovilla e Macedo (1998), em estudo de palavras e não palavras ou pseudopalavras, observaram que quanto mais longa a ...

Avaliacao Psicologica, Jun 1, 2005

... Josiane Maria de Freitas Tonelotto 1 ; Lineu Corrêa Fonseca I ; Glória MSA Tedrus II ; Samant... more ... Josiane Maria de Freitas Tonelotto 1 ; Lineu Corrêa Fonseca I ; Glória MSA Tedrus II ; Samanta Maria Visigalli Martins III ; Maria Agnes ... Capovilla, Capovilla e Macedo (1998), em estudo de palavras e não palavras ou pseudopalavras, observaram que quanto mais longa a ...

Dementia Neuropsychologia, 2010

Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms,... more Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms, but with frequent neuropsychological alterations. Objectives: To study the relationship between clinical and cognitive aspects and the perception of quality of life (QOL) in PD patients. Methods: Twenty consecutive patients (13 men) with idiopathic PD (mean age: 64.5y), mean disease time of 7.8 years and at stages 1-3 according to the modified Hoehn and Yahr staging scale (HYS), all outpatients from the Neurology Department of the Celso Pierro General and Maternity Hospital (PUC-Campinas), were analyzed. The following were applied: a clinical-neurological assessment, the Mini-Mental State Examination (MMSE), standard neuropsychological battery of the CERAD (Consortium to Establish a Registry for Alzheimer's Disease), Hamilton Depression Rating Scale (HAM-D) and a QOL questionnaire (Parkinson's Disease Questionnaire -PDQ-39). Statistical analysis was carried out at a significance level of p<0.05. Results: On the PDQ-39 under the sections total, mobility and activities of daily living, and the items motor compromise (HYS) and language of the MMSE were predictors of worse QOL. Verbal fluency was a factor for emotional well-being on the PDQ-39, whereas higher scores for HAM-D and worse performance on the item attention and calculation of the MMSE were associated with worse QOL in the social support section. Total score on the MMSE and educational level were QOL factors in cognition . Conclusions: The findings of the present study suggest that clinical, cognitive, motor or other depression-related factors contribute differently to the domains of QOL.

Dementia Neuropsychologia, 2010

Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms,... more Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms, but with frequent neuropsychological alterations. Objectives: To study the relationship between clinical and cognitive aspects and the perception of quality of life (QOL) in PD patients. Methods: Twenty consecutive patients (13 men) with idiopathic PD (mean age: 64.5y), mean disease time of 7.8 years and at stages 1-3 according to the modified Hoehn and Yahr staging scale (HYS), all outpatients from the Neurology Department of the Celso Pierro General and Maternity Hospital (PUC-Campinas), were analyzed. The following were applied: a clinical-neurological assessment, the Mini-Mental State Examination (MMSE), standard neuropsychological battery of the CERAD (Consortium to Establish a Registry for Alzheimer's Disease), Hamilton Depression Rating Scale (HAM-D) and a QOL questionnaire (Parkinson's Disease Questionnaire -PDQ-39). Statistical analysis was carried out at a significance level of p<0.05. Results: On the PDQ-39 under the sections total, mobility and activities of daily living, and the items motor compromise (HYS) and language of the MMSE were predictors of worse QOL. Verbal fluency was a factor for emotional well-being on the PDQ-39, whereas higher scores for HAM-D and worse performance on the item attention and calculation of the MMSE were associated with worse QOL in the social support section. Total score on the MMSE and educational level were QOL factors in cognition . Conclusions: The findings of the present study suggest that clinical, cognitive, motor or other depression-related factors contribute differently to the domains of QOL.

Avaliacao Psicologica, Jun 1, 2005

Fatal error: XSL transformation failed. in /home/scielo/www/htdocs/ class.XSLTransformerPHP5.php ... more Fatal error: XSL transformation failed. in /home/scielo/www/htdocs/ class.XSLTransformerPHP5.php on line 40

Avaliacao Psicologica, Jun 1, 2005

Fatal error: XSL transformation failed. in /home/scielo/www/htdocs/ class.XSLTransformerPHP5.php ... more Fatal error: XSL transformation failed. in /home/scielo/www/htdocs/ class.XSLTransformerPHP5.php on line 40

Journal of Epilepsy and Clinical Neurophysiology, 2007

ABSTRACT Epileptic seizures and olanzapine use: two cases report Introduction: Slowing and epilep... more ABSTRACT Epileptic seizures and olanzapine use: two cases report Introduction: Slowing and epileptiform activity in EEG-patterns as well as epileptic seizures have been published during antipsychotic therapy with phenothiazines and butyrophenones. More recently, olanzepine, a new class of antipsychotic drug for use in treatment of refractory schizophrenics has been associated with a low risk of epileptic seizure occurrence. Methods: We studied two patients, 45 and 37 years old, with schizophrenia and generalized epileptic seizures appearing, respectively, four and one month after starting olanzapine treatment. Their electroencephalogram showed spike-wave discharges generalized in one case and focal in the second patient. Conclusion: It was observed an association between epileptic seizures and olanzapine use.

Journal of Epilepsy and Clinical Neurophysiology, 2007

ABSTRACT Epileptic seizures and olanzapine use: two cases report Introduction: Slowing and epilep... more ABSTRACT Epileptic seizures and olanzapine use: two cases report Introduction: Slowing and epileptiform activity in EEG-patterns as well as epileptic seizures have been published during antipsychotic therapy with phenothiazines and butyrophenones. More recently, olanzepine, a new class of antipsychotic drug for use in treatment of refractory schizophrenics has been associated with a low risk of epileptic seizure occurrence. Methods: We studied two patients, 45 and 37 years old, with schizophrenia and generalized epileptic seizures appearing, respectively, four and one month after starting olanzapine treatment. Their electroencephalogram showed spike-wave discharges generalized in one case and focal in the second patient. Conclusion: It was observed an association between epileptic seizures and olanzapine use.

Rev Cienc Med, Jun 1, 2005

Rev Cienc Med, Jun 1, 2005

Revista De Ciencias Medicas, Nov 22, 2012

A avaliação da discriminação entre palavras e pseudopalavras tem sido utilizada para melhor compr... more A avaliação da discriminação entre palavras e pseudopalavras tem sido utilizada para melhor compreensão do processo de leitura e escrita.

Revista De Ciencias Medicas, Nov 22, 2012

A avaliação da discriminação entre palavras e pseudopalavras tem sido utilizada para melhor compr... more A avaliação da discriminação entre palavras e pseudopalavras tem sido utilizada para melhor compreensão do processo de leitura e escrita.

Revista De Ciencias Medicas, Dec 3, 2012

Revista De Ciencias Medicas, Dec 3, 2012

Dement Neuropsychol, Jun 1, 2010

Dement Neuropsychol, Jun 1, 2010

Arquivos De Neuro Psiquiatria, Sep 1, 2007

Arquivos De Neuro Psiquiatria, Sep 1, 2007

Clinical Eeg and Neuroscience Official Journal of the Eeg and Clinical Neuroscience Society, Jul 1, 2009

The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes... more The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes and cognitive disturbance (mild cognitive impairment or dementia) and the motor disturbance stage in Parkinson&#39;s disease (PD). Thirty-two PD patients (age = 67.2 +/- 10.0) and 26 normal subjects (age = 68.4 +/- 4.7) were assessed using a neurological evaluation, modified Hoehn and Yahr (HY) scale for PD, a Portuguese version of the CERAD neuropsychological battery (consortium to establish a registry for Alzheimer&#39;s disease) incorporating the Mini-mental Status Examination, Clinical Dementia Rating and an EEG analysis of absolute and relative band amplitude at rest. Four groups were compared: three with PD (7 patients with dementia, 10 with mild cognitive impairment and 15 with no cognitive disturbances) and the control group. The qEEG showed no significant differences between the control group and PD patients without cognitive disturbance. Abnormalities on the qEEG were essentially associated with the occurrence of mild cognitive impairment or dementia in patients with PD. There was an increase in the absolute and relative posterior theta amplitude in the groups with mild cognitive impairment or dementia and of the posterior absolute and relative delta amplitude in the group with dementia This study suggested qEEG as a possible physiological tool in the assessment of cognitive aspects in PD.

Clinical Eeg and Neuroscience Official Journal of the Eeg and Clinical Neuroscience Society, Jul 1, 2009

The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes... more The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes and cognitive disturbance (mild cognitive impairment or dementia) and the motor disturbance stage in Parkinson&#39;s disease (PD). Thirty-two PD patients (age = 67.2 +/- 10.0) and 26 normal subjects (age = 68.4 +/- 4.7) were assessed using a neurological evaluation, modified Hoehn and Yahr (HY) scale for PD, a Portuguese version of the CERAD neuropsychological battery (consortium to establish a registry for Alzheimer&#39;s disease) incorporating the Mini-mental Status Examination, Clinical Dementia Rating and an EEG analysis of absolute and relative band amplitude at rest. Four groups were compared: three with PD (7 patients with dementia, 10 with mild cognitive impairment and 15 with no cognitive disturbances) and the control group. The qEEG showed no significant differences between the control group and PD patients without cognitive disturbance. Abnormalities on the qEEG were essentially associated with the occurrence of mild cognitive impairment or dementia in patients with PD. There was an increase in the absolute and relative posterior theta amplitude in the groups with mild cognitive impairment or dementia and of the posterior absolute and relative delta amplitude in the group with dementia This study suggested qEEG as a possible physiological tool in the assessment of cognitive aspects in PD.

Avaliacao Psicologica, Jun 1, 2005

... Josiane Maria de Freitas Tonelotto 1 ; Lineu Corrêa Fonseca I ; Glória MSA Tedrus II ; Samant... more ... Josiane Maria de Freitas Tonelotto 1 ; Lineu Corrêa Fonseca I ; Glória MSA Tedrus II ; Samanta Maria Visigalli Martins III ; Maria Agnes ... Capovilla, Capovilla e Macedo (1998), em estudo de palavras e não palavras ou pseudopalavras, observaram que quanto mais longa a ...

Avaliacao Psicologica, Jun 1, 2005

... Josiane Maria de Freitas Tonelotto 1 ; Lineu Corrêa Fonseca I ; Glória MSA Tedrus II ; Samant... more ... Josiane Maria de Freitas Tonelotto 1 ; Lineu Corrêa Fonseca I ; Glória MSA Tedrus II ; Samanta Maria Visigalli Martins III ; Maria Agnes ... Capovilla, Capovilla e Macedo (1998), em estudo de palavras e não palavras ou pseudopalavras, observaram que quanto mais longa a ...