Bimlesh Lochab - Academia.edu (original) (raw)

Papers by Bimlesh Lochab

Journal of materials chemistry. A, 2024

The Cambridge Structural Database, 2023

ACS sustainable chemistry & engineering, Apr 24, 2024

ACS applied bio materials, Apr 17, 2024

Green Chemistry, Dec 31, 2023

Journal of materials chemistry. A, Materials for energy and sustainability, Dec 31, 2022

Macromolecules, Feb 15, 2024

RSC Advances, 2014

Exploration of sustainable alternative to chemicals derived from petro-based industries is the cu... more Exploration of sustainable alternative to chemicals derived from petro-based industries is the current challenge for maintaining the balance between needs of changing world while preserving the nature. The major source for sustainable chemicals is either the natural existing plant sources or waste generated from agro-based industries. The utility of such resources will supplement new processed materials with different sets of properties, and environmental friendliness due to their biodegradability and low toxicity during preparation, usage and discard. Amongst other day to day use polymers, phenolic resins account for vast usage. Replacement of petro-based monomers such as phenol and its derivatives either partly or completely utilized for the synthesis of such resins is ongoing. Extraction of naturally phenolic components from cashew nut shell liquid (CNSL), lignin, tannin, palm oil, coconut shell tar (CST) or from agricultural and industrial waste, their utilization as a synthon for the preparation of a bio-based polymers and properties obtained is reviewed in this paper. This review article is designed to acknowledge efforts of researchers towards 3C motto-not only trying to Create but also adapting the principles to Conserve, and Care for a sustainable environment. This review paper describes how extraction, separation and recovery of desired phenolic compounds occur recently? How substituted phenol compounds unmodified/modified act as monomer for polymerization? How the presences of sustainable phenolic material affect properties of polymer? There are about 600 references cited and still there is lot to unfold in this research area.

Journal Of Macromolecular Science, Part A, Dec 31, 2003

Macromolecules, Oct 7, 2021

Materials Research Innovations, Oct 1, 2002

A dendritic polyester based on pentaerythritol and 1,2,4-benzenetricarboxylic acid anhydride foll... more A dendritic polyester based on pentaerythritol and 1,2,4-benzenetricarboxylic acid anhydride followed by modification with glycidyl methacrylate was synthesised by using a divergent approach. The dendrimer (D-2) thus obtained had approximately eight double bonds. Several blends of D-2 with varying proportions of bismethacryloxy derivative of diglycidyl ether of bisphenol-A having styrene as a reactive diluent (VE resin) were prepared. The Brookfield viscosity of VE resin increased with an increase in D-2 content in the blends. Curing behaviour of these resins in the presence of AIBN was investigated by DSC. No significant change in curing exotherm was observed by addition of D-2 to the VE resin. Isothermal curing of resin samples in the presence of AIBN was done at 60°C for 5 h and then at 150°C for 90 mins. A significant improvement in char yield at 600°C in nitrogen atmosphere was observed in samples containing D-2. Mechanical properties of glass fiber reinforced laminates with 31 ± 3% of resin content (w/w) were also determined. Smoke density of laminates increased with decrease in D-2 content in the resin, whereas only a marginal effect on limiting oxygen index was observed.

Macromolecular Chemistry and Physics, May 6, 2016

FlatChem, 2019

Among 2-D nanostructures, graphene oxide is considered as the most attractive precursor nanomater... more Among 2-D nanostructures, graphene oxide is considered as the most attractive precursor nanomaterial for the utility of graphene in a variety of applications. There are problems associated with its mass production, which demands development of better and easier synthetic protocols. In addition, a chemical approach with a better control over degree of oxidation and nature of functionalities is simultaneously crucial for designing their structural modifications and the corresponding applications. Herein, three types of GOs are prepared by Hummers, Intermediate and Improved method. A primary reaction step in GO synthesis is the formation of graphite intercalation compounds (GICs). The efficiency of oxidation and intercalant efficiency, non-oxidative Bronsted acid H 3 PO 4 /H 2 SO 4 and H 2 SO 4 are studied and properties are compared with the classical intercalant, H 2 SO 4 /NaNO 3. A modulation in degree and nature of oxidative defects, flake size and stability of aqueous dispersion is observed, as supported by various analytical techniques. Depending upon the reaction conditions, the synthesized GOs revealed predominance of different type of oxidative functionalities and thereby reflected in associated physical properties, which is helpful to guide their usage for specific applications.

ACS Sustainable Chemistry & Engineering, Nov 28, 2017

We report on the preparation of hexa-functional cardanol (renewable phenolic compound) benzoxazin... more We report on the preparation of hexa-functional cardanol (renewable phenolic compound) benzoxazine with a phosphazene core (CPN) for use as a greener eco-friendly halogen-free flame retardant reactive additive for the formation of sustainable polyphosphazene polybenzoxazine networks for flame resistant applications. The structure and purity of the monomer was confirmed by fourier transform infrared (FTIR), nuclear magnetic resonance (1 H-, 13 C-, 31 P-NMR) and gel permeation chromatography (GPC) studies. The CPN monomer showed good compatibility with benzoxazine monomer (CPN0) as suggested by the co-curing studies. The thermal properties of the copolymer can be directly tuned by altering the composition of the monomer blend. The occurrence of phosphazene-phosphazane thermal rearrangement is also suggested for the thermal behaviour (thermogravimetry analysis, TGA) at higher loading of CPN in the monomer feed ratio. An improvement in mechanical properties of the copolymer with increase in glass transition Page 1 of 47 ACS Paragon Plus Environment ACS Sustainable Chemistry & Engineering 2 temperature was confirmed by enhancement in crosslink density as compared to neat polybenzoxazine. The reactive nature and presence of phosphazene core improved both the smoke density rating, vertical burning rating and led to higher limiting oxygen index (LOI). The FTIR and scanning electron microscopy (SEM) studies of residual char supported the formation of functionalities and morphologies favorable to support the flame resistance behavior of polymer by incorporation of reactive benzoxazine with phosphazene core. Finally, we demonstrate that incorporation of cardanol phosphazene network has good compatibility with the polybenzoxazine phenolic thermosets with improvement in flame retardancy. The higher cardanol (65.7%) and phosphorous content (3.4%), and reactive nature of synthesised compound is attractive as a sustainable additive with the scope of their utilisation with other polymeric resins.

Materials advances, 2023

Electrochemical energy storage devices, including supercapacitors and metal-ion batteries, are so... more Electrochemical energy storage devices, including supercapacitors and metal-ion batteries, are some of the most sustainable energy technologies. The advancement of layered materials constantly improves the charge storage capacity of these devices by facilitating the intercalation/de-intercalation mechanism. In the present study, we have prepared a PANI/VS 2 composite material using a facile method and used it to fabricate quasi-solid-state supercapacitors (QSSCs) and zinc ion batteries (ZIBs). In situ growth of PANI on the layered VS 2 improved the conductivity and charge acceptor sites during the cycling process. The PANI/VS 2 composite showed an specific capacitance of 822 F g À1 at 2 A g À1 discharge current density due to the pseudocapacitance contribution from PANI. In addition, the observed nanowire network of PANI over the VS 2 surface facilitated the electrolyte accessibility. The assembled ZIB, with PANI/VS 2 as the cathode, showed a charge storage capacity of 219 mA h g À1 at a discharge rate of 0.1 A g À1 with a coulombic efficiency of B100% after 750 continuous cycles at 3 A g À1. The observed higher charge storage capacity and the cycling reversibility of the devices are attributed to the robustness of the prepared PANI/VS 2 composite material.

Frontiers in Oncology, Aug 16, 2022

Glioblastoma multiforme (GBM) is known as the primary malignant and most devastating form of tumo... more Glioblastoma multiforme (GBM) is known as the primary malignant and most devastating form of tumor found in the central nervous system of the adult population. The active pharmaceutical component in current chemotherapy regimens is mostly hydrophobic and poorly water-soluble, which hampers clinical implications. Nanodrug formulations using nanocarriers loaded with such drugs assisted in water dispersibility, improved cellular permeability, and drug efficacy at a low dose, thus adding to the overall practical value. Here, we successfully developed a water-dispersible and biocompatible nanocargo (GO-PEG) based on covalently modified graphene oxide (GO) with a 6armed poly(ethylene glycol) amine dendrimer for effective loading of the two hydrophobic anticancer drug molecules, CPI444 and vatalanib. These drug molecules target adenosine receptor (A2AR), vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), and type III stem cell receptor tyrosine kinase (c-KIT), which plays a crucial role in cancers. The effective cellular delivery of the drugs when loaded on GO-PEG is attributed to the increased permeability of the drug-nanoconjugate formulation. We observed that this combinatorial drug treatment with nanocargo resulted in a significant reduction in the overall cell survival as supported by reduced calcium levels and stem cell markers such as Oct4 and Nanog, which are two of the prime factors for GBM stem cell proliferation. Furthermore, reduced expression of CD24 upon treatment with nanoformulation impeded cellular migration. Cellular assays confirmed inhibition of cell proliferation, migration, and angiogenic potential of GBM treated with GO-PEG-Drug conjugates. Ultimately, GBM U87 cells assumed programmed cell death at a very low concentration due to nanocarriermediated drug delivery along with the chosen combination of drugs.

ACS Sustainable Chemistry & Engineering, Sep 5, 2022

ACS applied bio materials, Sep 27, 2020

Development of drugs to tackle with ever-increasing cases of cancer and many others including any... more Development of drugs to tackle with ever-increasing cases of cancer and many others including any pandemic is itself challenging. Repurposing existing drugs is an upcoming drug development strategy established on the reuse of existing licensed drugs to ensure accessible, sustainable and affordable care against cancer. Herein, we presented a nano-chemotherapeutic approach based on PEGylated graphene oxide (GO-PEG) loaded with superparamagnetic iron oxide NPs and sustainable origin drug, artesunate (ART) to kill the cancerous cells. GO-PEG provided a larger surface area to load the dual cargo at a high loading efficiency, iron oxide NPs (~40%) and ART (~13%), and simultaneously affected nanotization and crystallinity of iron oxide nanoparticles. Morphology and internalization of NPs was determined qualitatively

ACS applied bio materials, Jun 27, 2022