R. Lovato - Academia.edu (original) (raw)
Papers by R. Lovato
Reumatismo
The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory Drugs (NSAIDs) in p... more The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory Drugs (NSAIDs) in patients with a history of osteoporotic vertebral fractures. We investigated 119 patients with postmenopausal osteoporosis complicated by one or more non recent vertebral fractures. More than 60% of the patients took at least one dose of NSAID weekly. The most prescribed NSAID was nimesulide, at a dose with an exclusively antalgic effect. Patients with wedge fracture and those with a documented vertebral fracture in the last 12 months were those taking NSAIDs more frequently. 77% of the patients that used NSAIDs had concomitant features of osteoarthritis, mainly at the spine or at the knee. The use of NSAIDs was negatively related to the use of specific therapy for osteoporosis, particularly for oral daily tablets. This study highlights the significant use of NSAIDs in patients with osteoporotic vertebral fractures and the overlap between osteoporosis, osteoarthritis and related treatments.
Reumatismo, 2011
ca 80.000 ricoveri per fratture di femore, il 66% dei quali riguardava donne di età superiore ai ... more ca 80.000 ricoveri per fratture di femore, il 66% dei quali riguardava donne di età superiore ai 75 anni, in gran parte osteoporotiche (3); nel 2005 questi ricoveri sono risultati più di 94.000 (4). Si stima che per affrontare il problema delle fratture di femore degli anziani il Servizio Sanitario Nazionale sostenga annualmente una spesa di oltre 1 miliardo di euro, superiore a quella per infarto miocardio (IMA) (5). È noto anche che la frattura di femore, specie nella popolazione anziana, è causa non trascurabile di mortalità, di disabilità e di istituzionalizzazione (6-11). Circa il 5% dei pazienti muore per complicanze in fase acuta ed il 15-25% entro un anno (1). La disabilità deambulatoria è permanente nel 20%
SUMMARY Objective: The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory ... more SUMMARY Objective: The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory Drugs (NSAIDs) in patients with a history of osteoporotic vertebral fractures. Methods: We investigated 119 patients with postmenopausal osteoporosis complicated by one or more non recent ver- tebral fractures. Results: More than 60% of the patients took at least one dose of NSAID weekly.
Disability and Rehabilitation, 2011
Purpose. To evaluate retrospectively the efficiency of our rehabilitation programme for patients ... more Purpose. To evaluate retrospectively the efficiency of our rehabilitation programme for patients with Prader-Willi Syndrome. In total, 49 patients were examined, 21 female and 28 male, the youngest in their late teens. Prader-Willi syndrome is generally characterised by cognitive impairment, behavioural abnormalities, and hyperphagia. Patients are usually considerably adverse to any form of physical exercise, and despite hormonal therapy, weight control in adult patients can be difficult. Methods. Four times a year, disease-specific residential programmes were organised, each lasting 4 weeks. The patients were restricted to a 1500 Kcal diet. In addition, they were required to do 6.5 h of physical exercise daily, stamina being built up by using music therapy, psychomotor therapy, education and entertainment activities. Results. BMI decreased by 2.1 average points in every residential session. For three patients who attended our treatments regularly, a reduction of 8.9 points over 6 years was recorded. An attendance of at least three sessions per year seemed to be necessary to substantially reduce weight. Conclusions. A multidisciplinary approach and a daily calorie-counted diet can lead to significant weight loss in teenage and adult PWS patients. This approach would also be suitable in treating patients with other obesity syndromes with mental retardation.
Journal of Orthopaedics and Traumatology, 2004
Long-term survivorship of total hip arthroplasty is strictly related to the bone-host interaction... more Long-term survivorship of total hip arthroplasty is strictly related to the bone-host interaction, where bone remodeling is the main factor . The evaluation of bone mass surrounding the implant is the most reliable method, starting from the common observation that bone reacts to stable and well functioning implants with bone apposition according to Wolff's law, while bone resorption is the typical response to an unstable and mal-loading implant .
Reumatismo
The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory Drugs (NSAIDs) in p... more The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory Drugs (NSAIDs) in patients with a history of osteoporotic vertebral fractures. We investigated 119 patients with postmenopausal osteoporosis complicated by one or more non recent vertebral fractures. More than 60% of the patients took at least one dose of NSAID weekly. The most prescribed NSAID was nimesulide, at a dose with an exclusively antalgic effect. Patients with wedge fracture and those with a documented vertebral fracture in the last 12 months were those taking NSAIDs more frequently. 77% of the patients that used NSAIDs had concomitant features of osteoarthritis, mainly at the spine or at the knee. The use of NSAIDs was negatively related to the use of specific therapy for osteoporosis, particularly for oral daily tablets. This study highlights the significant use of NSAIDs in patients with osteoporotic vertebral fractures and the overlap between osteoporosis, osteoarthritis and related treatments.
Reumatismo, 2011
ca 80.000 ricoveri per fratture di femore, il 66% dei quali riguardava donne di età superiore ai ... more ca 80.000 ricoveri per fratture di femore, il 66% dei quali riguardava donne di età superiore ai 75 anni, in gran parte osteoporotiche (3); nel 2005 questi ricoveri sono risultati più di 94.000 (4). Si stima che per affrontare il problema delle fratture di femore degli anziani il Servizio Sanitario Nazionale sostenga annualmente una spesa di oltre 1 miliardo di euro, superiore a quella per infarto miocardio (IMA) (5). È noto anche che la frattura di femore, specie nella popolazione anziana, è causa non trascurabile di mortalità, di disabilità e di istituzionalizzazione (6-11). Circa il 5% dei pazienti muore per complicanze in fase acuta ed il 15-25% entro un anno (1). La disabilità deambulatoria è permanente nel 20%
SUMMARY Objective: The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory ... more SUMMARY Objective: The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory Drugs (NSAIDs) in patients with a history of osteoporotic vertebral fractures. Methods: We investigated 119 patients with postmenopausal osteoporosis complicated by one or more non recent ver- tebral fractures. Results: More than 60% of the patients took at least one dose of NSAID weekly.
Disability and Rehabilitation, 2011
Purpose. To evaluate retrospectively the efficiency of our rehabilitation programme for patients ... more Purpose. To evaluate retrospectively the efficiency of our rehabilitation programme for patients with Prader-Willi Syndrome. In total, 49 patients were examined, 21 female and 28 male, the youngest in their late teens. Prader-Willi syndrome is generally characterised by cognitive impairment, behavioural abnormalities, and hyperphagia. Patients are usually considerably adverse to any form of physical exercise, and despite hormonal therapy, weight control in adult patients can be difficult. Methods. Four times a year, disease-specific residential programmes were organised, each lasting 4 weeks. The patients were restricted to a 1500 Kcal diet. In addition, they were required to do 6.5 h of physical exercise daily, stamina being built up by using music therapy, psychomotor therapy, education and entertainment activities. Results. BMI decreased by 2.1 average points in every residential session. For three patients who attended our treatments regularly, a reduction of 8.9 points over 6 years was recorded. An attendance of at least three sessions per year seemed to be necessary to substantially reduce weight. Conclusions. A multidisciplinary approach and a daily calorie-counted diet can lead to significant weight loss in teenage and adult PWS patients. This approach would also be suitable in treating patients with other obesity syndromes with mental retardation.
Journal of Orthopaedics and Traumatology, 2004
Long-term survivorship of total hip arthroplasty is strictly related to the bone-host interaction... more Long-term survivorship of total hip arthroplasty is strictly related to the bone-host interaction, where bone remodeling is the main factor . The evaluation of bone mass surrounding the implant is the most reliable method, starting from the common observation that bone reacts to stable and well functioning implants with bone apposition according to Wolff's law, while bone resorption is the typical response to an unstable and mal-loading implant .