Manish Trivedi - Academia.edu (original) (raw)
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Papers by Manish Trivedi
Antimicrobial agents and chemotherapy, Jan 31, 2015
We studied the clinical and economic impact of a protocol encouraging fidaxomicin first-line for ... more We studied the clinical and economic impact of a protocol encouraging fidaxomicin first-line for Clostridium difficile infection (CDI) in patients hospitalized during a two-year period. This study evaluated patients who received oral vancomycin or fidaxomicin for the treatment of CDI during a 2-year period. All included patients were eligible for fidaxomicin via a protocol that encouraged its use for select patients. The primary clinical endpoint was 90-day readmission with a diagnosis of CDI. Hospital charges and insurance reimbursements for readmissions were calculated along with the cost of CDI therapy to estimate the financial impact of the choice of therapy. Recurrences were seen in 10/49 (20.4%) fidaxomicin patients and 19/46 (41.3%) vancomycin patients (p=0.027). In a multivariate analysis that included severity of CDI, serum creatinine increases, and concomitant antibiotic use, only fidaxomicin was significantly associated with decreased recurrence (aOR 0.33, 95% CI 0.12-0.9...
Rainfall is a phenomenon, which directly or indirectly affects all the sectors like agriculture, ... more Rainfall is a phenomenon, which directly or indirectly affects all the sectors like agriculture, insurance, industry and other allied fields. Modeling data that correspond to rainfall accumulated over long periods presents the challenging problem of dealing with a random variable that has a point mass at zero, which corresponds to dry periods that occur with positive probability. One-way to overcome a difficulty that it is assumes that the data correspond to a normal variate that has been truncated and transformed. The dry periods correspond to the (unobserved) negative values and the wet periods correspond to some power of the positive ones. This manuscript identified the more comprehensive pattern of yearly extreme rainfall behavior based on the Markov Chain models. For this purpose, we derived annual maximum daily rainfall from 1956 to 2006 and frequency distribution table formed. The class interval treated as states and then uncertainty under various states occupied by formation...
The stratification in sample surveys needs the knowledge of strata size and stratum frames both. ... more The stratification in sample surveys needs the knowledge of strata size and stratum frames both. When any one of them is not available, the stratification is restricted. This paper presents a modified class of estimators for estimating the population mean under the setup of poststratified cluster sampling. Three proposed weighted cluster estimators are derived using the weight structure of Agarwal and Panda (1993) for the post stratified cluster design. Properties of these estimators are derived in the form of theorems and their mutual comparison are made. A new technique for pooled estimation is also incorporated.
Antimicrobial agents and chemotherapy, Jan 31, 2015
We studied the clinical and economic impact of a protocol encouraging fidaxomicin first-line for ... more We studied the clinical and economic impact of a protocol encouraging fidaxomicin first-line for Clostridium difficile infection (CDI) in patients hospitalized during a two-year period. This study evaluated patients who received oral vancomycin or fidaxomicin for the treatment of CDI during a 2-year period. All included patients were eligible for fidaxomicin via a protocol that encouraged its use for select patients. The primary clinical endpoint was 90-day readmission with a diagnosis of CDI. Hospital charges and insurance reimbursements for readmissions were calculated along with the cost of CDI therapy to estimate the financial impact of the choice of therapy. Recurrences were seen in 10/49 (20.4%) fidaxomicin patients and 19/46 (41.3%) vancomycin patients (p=0.027). In a multivariate analysis that included severity of CDI, serum creatinine increases, and concomitant antibiotic use, only fidaxomicin was significantly associated with decreased recurrence (aOR 0.33, 95% CI 0.12-0.9...
Rainfall is a phenomenon, which directly or indirectly affects all the sectors like agriculture, ... more Rainfall is a phenomenon, which directly or indirectly affects all the sectors like agriculture, insurance, industry and other allied fields. Modeling data that correspond to rainfall accumulated over long periods presents the challenging problem of dealing with a random variable that has a point mass at zero, which corresponds to dry periods that occur with positive probability. One-way to overcome a difficulty that it is assumes that the data correspond to a normal variate that has been truncated and transformed. The dry periods correspond to the (unobserved) negative values and the wet periods correspond to some power of the positive ones. This manuscript identified the more comprehensive pattern of yearly extreme rainfall behavior based on the Markov Chain models. For this purpose, we derived annual maximum daily rainfall from 1956 to 2006 and frequency distribution table formed. The class interval treated as states and then uncertainty under various states occupied by formation...
The stratification in sample surveys needs the knowledge of strata size and stratum frames both. ... more The stratification in sample surveys needs the knowledge of strata size and stratum frames both. When any one of them is not available, the stratification is restricted. This paper presents a modified class of estimators for estimating the population mean under the setup of poststratified cluster sampling. Three proposed weighted cluster estimators are derived using the weight structure of Agarwal and Panda (1993) for the post stratified cluster design. Properties of these estimators are derived in the form of theorems and their mutual comparison are made. A new technique for pooled estimation is also incorporated.