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Papers by Marcela Contreras

Research paper thumbnail of Creutzfeldt-Jakob disease and blood transfusion

BMJ, Jul 20, 1991

Differences between peak flow meters on prescription.

Research paper thumbnail of Serum alanine aminotransferase (ALT) and gamma-glutamyltransferase (gamma-GT) activities in north London blood donors

Journal of Clinical Pathology, 1987

Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in... more Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in over 2000 north London blood donors. The results were compared with those from the United States. The percentage of the total donor population with ALT activities above 40 IU/l in 1986 was greater than that found in our earlier studies in 1973 and 1982 (4-6% compared with 2-8% and 3 1%, respectively). There was a noticeable difference in the ALT distribution between male and female donors: mean + 225 SD for male donors was 55-3 IU/1, while that for female donors was 30-8 IU/l at 37°C. In stability studies the optimal temperature for short term storage (10 days) was 4°C (6 4% loss of activity after 10 days). Surprisingly, storage at lower temperatures (-35°C and-80°C) resulted in greater loss of activity. 1340 copyright.

Research paper thumbnail of Blood donors at high risk of transmitting the acquired immune deficiency syndrome

Research paper thumbnail of Viral Infections Transmitted by Blood Transfusion

Journal of the Royal Society of Medicine, 1990

Research paper thumbnail of HLA-A, -B and -DR antigen frequencies of the London Cord Blood Bank units differ from those found in established bone marrow donor registries

Bone Marrow Transplantation, 2000

Patients requiring allogeneic stem cell transplantation who do not have an HLA-matched related do... more Patients requiring allogeneic stem cell transplantation who do not have an HLA-matched related donor can sometimes obtain an unrelated donor by searching volunteer registries. The majority of donors in the registries are Caucasoid, which results in a lower probability of a non-Caucasoid patient finding a suitable donor. Cord blood is increasingly used as a source of haematopoietic stem cells for allogeneic bone marrow reconstitution and so far the London Cord Blood Bank has banked almost 3000 cord blood units. An analysis of the first 1500 units banked showed that more than 30% of the London Cord Blood Bank units are derived from UK ethnic minorities compared with only 2% of individuals recruited locally for the British Bone Marrow Registry (BBMR). The HLA types found in these cord blood units reflect their ethnic diversity and include: HLA-A34, A36, A80, B75, B61, B53, B78, B81 and B82. The units stored by the London Cord Blood Bank show an HLA profile which differs considerably from that of locally typed adult volunteers for the BBMR panel and this should help to increase the chances of obtaining acceptably HLAmatched donors for patients from ethnic minorities. Bone Marrow Transplantation (2000) 25, 475-481.

Research paper thumbnail of Transfusion Microbiology: Preface

Research paper thumbnail of Transfusion Microbiology: Glossary

Research paper thumbnail of Processing and components: leucodepletion and pathogen reduction

Transfusion Microbiology, 2008

Research paper thumbnail of Prevention of Aids

Research paper thumbnail of Red cell transfusions and blood groups

Research paper thumbnail of The Detection of Alloantibodies against Red Cells in Patients with Warm-Type Autoimmune Haemolytic Anaemia

Research paper thumbnail of Abo Status and T-Cell Help

Research paper thumbnail of Editorial: allogeneic blood usage - risks and benefits

Transfusion Alternatives in Transfusion Medicine, 2008

Research paper thumbnail of ANTI-Rh(D) IMMUNOGLOBULIN FOR IMMUNE THROMBOCYTOPENIC PURPURA

Research paper thumbnail of II. Establecimiento del Banco de Sangre de Cuerda de Londres y Trasplante de Sangre de Cuerda

Research paper thumbnail of Cord blood banking in London: the first 1000 collections

Bone Marrow Transplantation, 1999

Research paper thumbnail of Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD

Nature

... Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD. Graham S. Jackson 1 , Jonathan A... more ... Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD. Graham S. Jackson 1 , Jonathan A. Beck 1 , Cristina Navarrete 2, 3 , Juliette Brown 2 , P. Margaret Sutton 4 , Marcela Contreras 2, 5 & John Collinge 1. Top of page Abstract. ...

Research paper thumbnail of Diagnosis and treatment of patients refractory to platelet transfusions

Blood Rev, 1998

... Diagnosis and treatment of patients refractory to platelet transfusions. Contreras M. Royal F... more ... Diagnosis and treatment of patients refractory to platelet transfusions. Contreras M. Royal Free and UCL Medical School, London and South East Zone of the National Blood Service, UK. PMID: 9950090 [PubMed - indexed for MEDLINE]. Publication Types: Review. MeSH Terms. ...

Research paper thumbnail of Frequency and Inheritance of the Bx a (Box) Antigen

Vox Sang, 1980

Two Bx (a+) families are described, and Bxa is shown to segregate independently from several gene... more Two Bx (a+) families are described, and Bxa is shown to segregate independently from several genetic markers. Anti-Bxa has so far only been detected as an antibody without an identifiable stimulus.

Research paper thumbnail of METHODS OF MEASUREMENT OF Rh HAEMOLYTIC DISEASE

Research paper thumbnail of Creutzfeldt-Jakob disease and blood transfusion

BMJ, Jul 20, 1991

Differences between peak flow meters on prescription.

Research paper thumbnail of Serum alanine aminotransferase (ALT) and gamma-glutamyltransferase (gamma-GT) activities in north London blood donors

Journal of Clinical Pathology, 1987

Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in... more Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in over 2000 north London blood donors. The results were compared with those from the United States. The percentage of the total donor population with ALT activities above 40 IU/l in 1986 was greater than that found in our earlier studies in 1973 and 1982 (4-6% compared with 2-8% and 3 1%, respectively). There was a noticeable difference in the ALT distribution between male and female donors: mean + 225 SD for male donors was 55-3 IU/1, while that for female donors was 30-8 IU/l at 37°C. In stability studies the optimal temperature for short term storage (10 days) was 4°C (6 4% loss of activity after 10 days). Surprisingly, storage at lower temperatures (-35°C and-80°C) resulted in greater loss of activity. 1340 copyright.

Research paper thumbnail of Blood donors at high risk of transmitting the acquired immune deficiency syndrome

Research paper thumbnail of Viral Infections Transmitted by Blood Transfusion

Journal of the Royal Society of Medicine, 1990

Research paper thumbnail of HLA-A, -B and -DR antigen frequencies of the London Cord Blood Bank units differ from those found in established bone marrow donor registries

Bone Marrow Transplantation, 2000

Patients requiring allogeneic stem cell transplantation who do not have an HLA-matched related do... more Patients requiring allogeneic stem cell transplantation who do not have an HLA-matched related donor can sometimes obtain an unrelated donor by searching volunteer registries. The majority of donors in the registries are Caucasoid, which results in a lower probability of a non-Caucasoid patient finding a suitable donor. Cord blood is increasingly used as a source of haematopoietic stem cells for allogeneic bone marrow reconstitution and so far the London Cord Blood Bank has banked almost 3000 cord blood units. An analysis of the first 1500 units banked showed that more than 30% of the London Cord Blood Bank units are derived from UK ethnic minorities compared with only 2% of individuals recruited locally for the British Bone Marrow Registry (BBMR). The HLA types found in these cord blood units reflect their ethnic diversity and include: HLA-A34, A36, A80, B75, B61, B53, B78, B81 and B82. The units stored by the London Cord Blood Bank show an HLA profile which differs considerably from that of locally typed adult volunteers for the BBMR panel and this should help to increase the chances of obtaining acceptably HLAmatched donors for patients from ethnic minorities. Bone Marrow Transplantation (2000) 25, 475-481.

Research paper thumbnail of Transfusion Microbiology: Preface

Research paper thumbnail of Transfusion Microbiology: Glossary

Research paper thumbnail of Processing and components: leucodepletion and pathogen reduction

Transfusion Microbiology, 2008

Research paper thumbnail of Prevention of Aids

Research paper thumbnail of Red cell transfusions and blood groups

Research paper thumbnail of The Detection of Alloantibodies against Red Cells in Patients with Warm-Type Autoimmune Haemolytic Anaemia

Research paper thumbnail of Abo Status and T-Cell Help

Research paper thumbnail of Editorial: allogeneic blood usage - risks and benefits

Transfusion Alternatives in Transfusion Medicine, 2008

Research paper thumbnail of ANTI-Rh(D) IMMUNOGLOBULIN FOR IMMUNE THROMBOCYTOPENIC PURPURA

Research paper thumbnail of II. Establecimiento del Banco de Sangre de Cuerda de Londres y Trasplante de Sangre de Cuerda

Research paper thumbnail of Cord blood banking in London: the first 1000 collections

Bone Marrow Transplantation, 1999

Research paper thumbnail of Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD

Nature

... Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD. Graham S. Jackson 1 , Jonathan A... more ... Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD. Graham S. Jackson 1 , Jonathan A. Beck 1 , Cristina Navarrete 2, 3 , Juliette Brown 2 , P. Margaret Sutton 4 , Marcela Contreras 2, 5 & John Collinge 1. Top of page Abstract. ...

Research paper thumbnail of Diagnosis and treatment of patients refractory to platelet transfusions

Blood Rev, 1998

... Diagnosis and treatment of patients refractory to platelet transfusions. Contreras M. Royal F... more ... Diagnosis and treatment of patients refractory to platelet transfusions. Contreras M. Royal Free and UCL Medical School, London and South East Zone of the National Blood Service, UK. PMID: 9950090 [PubMed - indexed for MEDLINE]. Publication Types: Review. MeSH Terms. ...

Research paper thumbnail of Frequency and Inheritance of the Bx a (Box) Antigen

Vox Sang, 1980

Two Bx (a+) families are described, and Bxa is shown to segregate independently from several gene... more Two Bx (a+) families are described, and Bxa is shown to segregate independently from several genetic markers. Anti-Bxa has so far only been detected as an antibody without an identifiable stimulus.

Research paper thumbnail of METHODS OF MEASUREMENT OF Rh HAEMOLYTIC DISEASE

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