Marcela Contreras - Academia.edu (original) (raw)
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Papers by Marcela Contreras
BMJ, Jul 20, 1991
Differences between peak flow meters on prescription.
Journal of Clinical Pathology, 1987
Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in... more Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in over 2000 north London blood donors. The results were compared with those from the United States. The percentage of the total donor population with ALT activities above 40 IU/l in 1986 was greater than that found in our earlier studies in 1973 and 1982 (4-6% compared with 2-8% and 3 1%, respectively). There was a noticeable difference in the ALT distribution between male and female donors: mean + 225 SD for male donors was 55-3 IU/1, while that for female donors was 30-8 IU/l at 37°C. In stability studies the optimal temperature for short term storage (10 days) was 4°C (6 4% loss of activity after 10 days). Surprisingly, storage at lower temperatures (-35°C and-80°C) resulted in greater loss of activity. 1340 copyright.
Journal of the Royal Society of Medicine, 1990
Bone Marrow Transplantation, 2000
Patients requiring allogeneic stem cell transplantation who do not have an HLA-matched related do... more Patients requiring allogeneic stem cell transplantation who do not have an HLA-matched related donor can sometimes obtain an unrelated donor by searching volunteer registries. The majority of donors in the registries are Caucasoid, which results in a lower probability of a non-Caucasoid patient finding a suitable donor. Cord blood is increasingly used as a source of haematopoietic stem cells for allogeneic bone marrow reconstitution and so far the London Cord Blood Bank has banked almost 3000 cord blood units. An analysis of the first 1500 units banked showed that more than 30% of the London Cord Blood Bank units are derived from UK ethnic minorities compared with only 2% of individuals recruited locally for the British Bone Marrow Registry (BBMR). The HLA types found in these cord blood units reflect their ethnic diversity and include: HLA-A34, A36, A80, B75, B61, B53, B78, B81 and B82. The units stored by the London Cord Blood Bank show an HLA profile which differs considerably from that of locally typed adult volunteers for the BBMR panel and this should help to increase the chances of obtaining acceptably HLAmatched donors for patients from ethnic minorities. Bone Marrow Transplantation (2000) 25, 475-481.
Transfusion Microbiology, 2008
Transfusion Alternatives in Transfusion Medicine, 2008
Bone Marrow Transplantation, 1999
Nature
... Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD. Graham S. Jackson 1 , Jonathan A... more ... Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD. Graham S. Jackson 1 , Jonathan A. Beck 1 , Cristina Navarrete 2, 3 , Juliette Brown 2 , P. Margaret Sutton 4 , Marcela Contreras 2, 5 & John Collinge 1. Top of page Abstract. ...
Blood Rev, 1998
... Diagnosis and treatment of patients refractory to platelet transfusions. Contreras M. Royal F... more ... Diagnosis and treatment of patients refractory to platelet transfusions. Contreras M. Royal Free and UCL Medical School, London and South East Zone of the National Blood Service, UK. PMID: 9950090 [PubMed - indexed for MEDLINE]. Publication Types: Review. MeSH Terms. ...
Vox Sang, 1980
Two Bx (a+) families are described, and Bxa is shown to segregate independently from several gene... more Two Bx (a+) families are described, and Bxa is shown to segregate independently from several genetic markers. Anti-Bxa has so far only been detected as an antibody without an identifiable stimulus.
BMJ, Jul 20, 1991
Differences between peak flow meters on prescription.
Journal of Clinical Pathology, 1987
Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in... more Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in over 2000 north London blood donors. The results were compared with those from the United States. The percentage of the total donor population with ALT activities above 40 IU/l in 1986 was greater than that found in our earlier studies in 1973 and 1982 (4-6% compared with 2-8% and 3 1%, respectively). There was a noticeable difference in the ALT distribution between male and female donors: mean + 225 SD for male donors was 55-3 IU/1, while that for female donors was 30-8 IU/l at 37°C. In stability studies the optimal temperature for short term storage (10 days) was 4°C (6 4% loss of activity after 10 days). Surprisingly, storage at lower temperatures (-35°C and-80°C) resulted in greater loss of activity. 1340 copyright.
Journal of the Royal Society of Medicine, 1990
Bone Marrow Transplantation, 2000
Patients requiring allogeneic stem cell transplantation who do not have an HLA-matched related do... more Patients requiring allogeneic stem cell transplantation who do not have an HLA-matched related donor can sometimes obtain an unrelated donor by searching volunteer registries. The majority of donors in the registries are Caucasoid, which results in a lower probability of a non-Caucasoid patient finding a suitable donor. Cord blood is increasingly used as a source of haematopoietic stem cells for allogeneic bone marrow reconstitution and so far the London Cord Blood Bank has banked almost 3000 cord blood units. An analysis of the first 1500 units banked showed that more than 30% of the London Cord Blood Bank units are derived from UK ethnic minorities compared with only 2% of individuals recruited locally for the British Bone Marrow Registry (BBMR). The HLA types found in these cord blood units reflect their ethnic diversity and include: HLA-A34, A36, A80, B75, B61, B53, B78, B81 and B82. The units stored by the London Cord Blood Bank show an HLA profile which differs considerably from that of locally typed adult volunteers for the BBMR panel and this should help to increase the chances of obtaining acceptably HLAmatched donors for patients from ethnic minorities. Bone Marrow Transplantation (2000) 25, 475-481.
Transfusion Microbiology, 2008
Transfusion Alternatives in Transfusion Medicine, 2008
Bone Marrow Transplantation, 1999
Nature
... Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD. Graham S. Jackson 1 , Jonathan A... more ... Pathogenesis: HLA-DQ7 antigen and resistance to variant CJD. Graham S. Jackson 1 , Jonathan A. Beck 1 , Cristina Navarrete 2, 3 , Juliette Brown 2 , P. Margaret Sutton 4 , Marcela Contreras 2, 5 & John Collinge 1. Top of page Abstract. ...
Blood Rev, 1998
... Diagnosis and treatment of patients refractory to platelet transfusions. Contreras M. Royal F... more ... Diagnosis and treatment of patients refractory to platelet transfusions. Contreras M. Royal Free and UCL Medical School, London and South East Zone of the National Blood Service, UK. PMID: 9950090 [PubMed - indexed for MEDLINE]. Publication Types: Review. MeSH Terms. ...
Vox Sang, 1980
Two Bx (a+) families are described, and Bxa is shown to segregate independently from several gene... more Two Bx (a+) families are described, and Bxa is shown to segregate independently from several genetic markers. Anti-Bxa has so far only been detected as an antibody without an identifiable stimulus.